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1XRU
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BU of 1xru by Molmil
Crystal Structure of 5-keto-4-deoxyuronate Isomerase from Eschericia coli
分子名称: 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, PENTAETHYLENE GLYCOL, ZINC ION
著者Crowther, R.L, Georgiadis, M.M.
登録日2004-10-15
公開日2005-04-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献The crystal structure of 5-keto-4-deoxyuronate isomerase from Escherichia coli
Proteins, 61, 2005
1KOO
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BU of 1koo by Molmil
THE CRYSTAL STRUCTURE AND MUTATIONAL ANALYSIS OF A NOVEL RNA-BINDING DOMAIN FOUND IN THE HUMAN TAP NUCLEAR MRNA EXPORT FACTOR
分子名称: TIP ASSOCIATING PROTEIN
著者Ho, D.N, Coburn, G.A, Kang, Y, Cullen, B.R, Georgiadis, M.M.
登録日2001-12-21
公開日2002-02-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor.
Proc.Natl.Acad.Sci.USA, 99, 2002
6B1Q
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BU of 6b1q by Molmil
Hydrogen Bonding Complementary, not size complementarity is key in the formation of the double helix
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*(CJ1)P*(CJ1)P*(CJ1))-3'), DNA (5'-D(P*(1AP)P*(1AP)P*(1AP)P*AP*TP*AP*AP*G)-3'), Reverse transcriptase
著者Singh, I, Georgiadis, M.M.
登録日2017-09-18
公開日2018-09-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献"Skinny" and "Fat" DNA: Two New Double Helices.
J. Am. Chem. Soc., 140, 2018
6B1S
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BU of 6b1s by Molmil
Hydrogen Bonding Complementary, not size complementarity is key in the formation of the double helix
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*AP*(CGY)P*(CGY)P*TP*TP*TP*AP*TP*AP*AP*G)-3'), Reverse transcriptase
著者Singh, I, Georgiadis, M.M.
登録日2017-09-18
公開日2018-09-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献"Skinny" and "Fat" DNA: Two New Double Helices.
J. Am. Chem. Soc., 140, 2018
6B1R
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BU of 6b1r by Molmil
Hydrogen Bonding Complementary, not size complementarity is key in the formation of the double helix
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(1WA))-3'), DNA (5'-D(P*(IGU)P*(IGU)P*(IGU)P*AP*TP*AP*AP*G)-3'), Reverse transcriptase
著者Singh, I, Georgiadis, M.M.
登録日2017-09-18
公開日2018-09-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献"Skinny" and "Fat" DNA: Two New Double Helices.
J. Am. Chem. Soc., 140, 2018
4MH8
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BU of 4mh8 by Molmil
The crystal structure of the monomeric reverse transcriptase from moloney murine leukemia virus
分子名称: Reverse transcriptase/ribonuclease H p80
著者Das, D, Georgiadis, M.M.
登録日2013-08-29
公開日2013-10-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The crystal structure of the monomeric reverse transcriptase from Moloney murine leukemia virus.
Structure, 12, 2004
7S03
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BU of 7s03 by Molmil
DNA-binding domain of human SETMAR in complex with Hsmar1 terminal inverted repeat (TIR) DNA
分子名称: Histone-lysine N-methyltransferase SETMAR, Hsmar1 terminal inverted repeats
著者Chen, Q, Georgiadis, M.M.
登録日2021-08-28
公開日2022-08-03
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structural and genome-wide analyses suggest that transposon-derived protein SETMAR alters transcription and splicing.
J.Biol.Chem., 298, 2022
1NND
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BU of 1nnd by Molmil
Arginine 116 is Essential for Nucleic Acid Recognition by the Fingers Domain of Moloney Murine Leukemia Virus Reverse Transcriptase
分子名称: Reverse Transcriptase
著者Crowther, R.L, Remeta, D.P, Minetti, C.A, Das, D, Montano, S.P, Georgiadis, M.M.
登録日2003-01-13
公開日2004-01-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and energetic characterization of nucleic acid-binding to the fingers domain of Moloney murine leukemia virus reverse transcriptase
Proteins, 57, 2004
2R2U
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BU of 2r2u by Molmil
Co(III)bleomycinB2 bithiazole/C-terminal tail domain bound to d(ATTTAGTTAACTAAAT) complexed with MMLV RT catalytic fragment
分子名称: DNA (5'-D(*DAP*DTP*DTP*DTP*DAP*DGP*DT)-3'), DNA (5'-D(P*DTP*DAP*DCP*DTP*DAP*DAP*DAP*DT)-3'), N-(4-{[amino(imino)methyl]amino}butyl)-2,4'-bi-1,3-thiazole-4-carboxamide, ...
著者Goodwin, K.D, Lewis, M.A, Long, E.C, Georgiadis, M.M.
登録日2007-08-27
公開日2008-07-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1I6J
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BU of 1i6j by Molmil
CRYSTAL STRUCTURE OF A PSEUDO-16-MER DNA WITH STACKED GUANINES AND TWO G-A MISPAIRS COMPLEXED WITH THE N-TERMINAL FRAGMENT OF MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE
分子名称: 5'-D(*AP*CP*GP*GP*GP*AP*CP*GP*AP*C)-3', 5'-D(*GP*TP*CP*GP*TP*C)-3', REVERSE TRANSCRIPTASE
著者Cote, M.L, Georgiadis, M.M.
登録日2001-03-02
公開日2001-09-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a pseudo-16-mer DNA with stacked guanines and two G-A mispairs complexed with the N-terminal fragment of Moloney murine leukemia virus reverse transcriptase.
Acta Crystallogr.,Sect.D, 57, 2001
1M6U
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Crystal Structure of a Novel DNA-binding domain from Ndt80, a Transcriptional Activator Required for Meiosis in Yeast
分子名称: Ndt80 protein, SULFATE ION
著者Montano, S.P, Cote, M.L, Fingerman, I, Pierce, M, Vershon, A.K, Georgiadis, M.M.
登録日2002-07-17
公開日2002-11-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the DNA-binding domain from Ndt80, a transcriptional activator required for meiosis in yeast
Proc.Natl.Acad.Sci.USA, 99, 2002
1M7U
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BU of 1m7u by Molmil
Crystal structure of a novel DNA-binding domain from Ndt80, a transcriptional activator required for meiosis in yeast
分子名称: Ndt80 protein
著者Montano, S.P, Cote, M.L, Fingerman, I, Pierce, M, Vershon, A.K, Georgiadis, M.M.
登録日2002-07-22
公開日2002-11-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the DNA-binding domain from Ndt80, a transcriptional activator required for meiosis in yeast
Proc.Natl.Acad.Sci.USA, 99, 2002
4OTN
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BU of 4otn by Molmil
Crystal structure of the C-terminal regulatory domain of murine GCN2
分子名称: 1,2-ETHANEDIOL, Eukaryotic translation initiation factor 2-alpha kinase 4, SULFATE ION
著者He, H, Georgiadis, M.M.
登録日2014-02-13
公開日2014-04-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures of GCN2 Protein Kinase C-terminal Domains Suggest Regulatory Differences in Yeast and Mammals.
J.Biol.Chem., 289, 2014
4OTM
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Crystal structure of the C-terminal domain from yeast GCN2
分子名称: Serine/threonine-protein kinase GCN2
著者He, H, Georgiadis, M.M.
登録日2014-02-13
公開日2014-04-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structures of GCN2 Protein Kinase C-terminal Domains Suggest Regulatory Differences in Yeast and Mammals.
J.Biol.Chem., 289, 2014
4QHE
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BU of 4qhe by Molmil
Crystal structure of Mg2+ bound human APE1
分子名称: 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION
著者He, H, Chen, Q, Georgiadis, M.M.
登録日2014-05-28
公開日2014-11-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I.
Biochemistry, 53, 2014
4QHD
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BU of 4qhd by Molmil
Crystal structure of apo human APE1
分子名称: 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) lyase
著者He, H, Chen, Q, Georgiadis, M.M.
登録日2014-05-28
公開日2014-11-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I.
Biochemistry, 53, 2014
4QH9
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BU of 4qh9 by Molmil
Crystal structure of Mn2+ bound human APE1
分子名称: 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) lyase, MANGANESE (II) ION
著者Chen, Q, He, H, Georgiadis, M.M.
登録日2014-05-27
公開日2014-11-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.175 Å)
主引用文献High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I.
Biochemistry, 53, 2014
4M95
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d(ATCCGTTATAACGGAT)complexed with Moloney Murine Leukemia virus reverse transcriptase catalytic fragment
分子名称: 1,2-ETHANEDIOL, 5' d(ATCCGTTA) 3', 5' d(TAACGGAT) 3', ...
著者Singh, I.
登録日2013-08-14
公開日2014-03-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献The structure of an authentic spore photoproduct lesion in DNA suggests a basis for recognition.
Acta Crystallogr.,Sect.D, 70, 2014
4M94
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d(ATCCGTTATAACGGAT) complexed with Moloney Murine Leukemia virus reverse transcriptase catalytic fragment
分子名称: 1,2-ETHANEDIOL, 5' d(ATCCGttA) 3', 5' d(TAACGGAT) 3', ...
著者Singh, I.
登録日2013-08-14
公開日2014-03-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献The structure of an authentic spore photoproduct lesion in DNA suggests a basis for recognition.
Acta Crystallogr.,Sect.D, 70, 2014
6X1Z
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Mre11 dimer in complex with small molecule modulator PFMJ
分子名称: (5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, ...
著者Arvai, A.S, Moiani, D, Tainer, J.A.
登録日2020-05-19
公開日2020-06-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response.
Prog.Biophys.Mol.Biol., 163, 2021
6X1Y
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Mre11 dimer in complex with small molecule modulator PFMI
分子名称: (5Z)-5-[(3-methoxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nuclease SbcCD subunit D
著者Arvai, A.S, Moiani, D, Tainer, J.A.
登録日2020-05-19
公開日2020-06-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response.
Prog.Biophys.Mol.Biol., 163, 2021
1G5P
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NITROGENASE IRON PROTEIN FROM AZOTOBACTER VINELANDII
分子名称: IRON/SULFUR CLUSTER, NITROGENASE IRON PROTEIN
著者Strop, P, Takahara, P.M, Chiu, H.J, Angove, H.C, Burgess, B.K, Rees, D.C.
登録日2000-11-01
公開日2001-01-31
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the all-ferrous [4Fe-4S]0 form of the nitrogenase iron protein from Azotobacter vinelandii.
Biochemistry, 40, 2001
1DE0
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MODULATING THE MIDPOINT POTENTIAL OF THE [4FE-4S] CLUSTER OF THE NITROGENASE FE PROTEIN
分子名称: IRON/SULFUR CLUSTER, NITROGENASE IRON PROTEIN
著者Jang, S.B, Seefeldt, L.C, Peters, J.W.
登録日1999-11-12
公開日2000-02-09
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Modulating the midpoint potential of the [4Fe-4S] cluster of the nitrogenase Fe protein.
Biochemistry, 39, 2000
2NIP
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NITROGENASE IRON PROTEIN FROM AZOTOBACTER VINELANDII
分子名称: IRON/SULFUR CLUSTER, NITROGENASE IRON PROTEIN
著者Komiya, H, Georgiadis, M.M, Chakrabarti, P, Woo, D, Kornuc, J.J, Rees, D.C.
登録日1998-05-11
公開日1998-11-11
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Conformational variability in structures of the nitrogenase iron proteins from Azotobacter vinelandii and Clostridium pasteurianum.
J.Mol.Biol., 280, 1998
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