7S03

DNA-binding domain of human SETMAR in complex with Hsmar1 terminal inverted repeat (TIR) DNA

Summary for 7S03

Entry DOI	10.2210/pdb7s03/pdb
Descriptor	Histone-lysine N-methyltransferase SETMAR, Hsmar1 terminal inverted repeats, ... (4 entities in total)
Functional Keywords	setmar, dna-binding domain, hsmar1, helix-turn-helix, hth, terminal inverted repeat, tir, dna binding protein-dna complex, dna binding protein/dna
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	29391.67
Authors	Chen, Q.,Georgiadis, M.M. (deposition date: 2021-08-28, release date: 2022-08-03)
Primary citation	Chen, Q.,Bates, A.M.,Hanquier, J.N.,Simpson, E.,Rusch, D.B.,Podicheti, R.,Liu, Y.,Wek, R.C.,Cornett, E.M.,Georgiadis, M.M. Structural and genome-wide analyses suggest that transposon-derived protein SETMAR alters transcription and splicing. J.Biol.Chem., 298:101894-101894, 2022 Cited by PubMed: 35378129 DOI: 10.1016/j.jbc.2022.101894 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.37 Å)

Structure validation