5IQP
| 14-3-3 PROTEIN TAU ISOFORM | 分子名称: | 14-3-3 protein theta, SULFATE ION | 著者 | Xiao, B, Smerdon, S.J, Gamblin, S.J. | 登録日 | 2016-03-11 | 公開日 | 2016-03-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | 主引用文献 | Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways Nature, 376, 1995
|
|
5AJM
| H5 (VN1194) Asn186Lys Mutant Haemagglutinin in Complex with Avian Receptor Analogue 3'SLN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ... | 著者 | Xiong, X, Xiao, H, Martin, S.R, Coombs, P.J, Liu, J, Collins, P.J, Vachieri, S.G, Walker, P.A, Lin, Y.P, McCauley, J.W, Gamblin, S.J, Skehel, J.J. | 登録日 | 2015-02-25 | 公開日 | 2015-03-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Enhanced Human Receptor Binding by H5 Haemagglutinins. Virology, 456, 2014
|
|
1LDN
| STRUCTURE OF A TERNARY COMPLEX OF AN ALLOSTERIC LACTATE DEHYDROGENASE FROM BACILLUS STEAROTHERMOPHILUS AT 2.5 ANGSTROMS RESOLUTION | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, L-LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Wigley, D.B, Gamblin, S.J, Turkenburg, J.P, Dodson, E.J, Piontek, K, Muirhead, H, Holbrook, J.J. | 登録日 | 1991-11-19 | 公開日 | 1994-01-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of a ternary complex of an allosteric lactate dehydrogenase from Bacillus stearothermophilus at 2.5 A resolution. J.Mol.Biol., 223, 1992
|
|
4Z4P
| Structure of the MLL4 SET Domain | 分子名称: | Histone-lysine N-methyltransferase 2D, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | 著者 | Zhang, Z, Mittal, A, Reid, J, Reich, S, Gamblin, S.J, Wilson, J.R. | 登録日 | 2015-04-02 | 公開日 | 2015-09-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Evolving Catalytic Properties of the MLL Family SET Domain. Structure, 23, 2015
|
|
4X3E
| |
5A3I
| Crystal Structure of a Complex formed between FLD194 Fab and Transmissible Mutant H5 Haemagglutinin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTI-HAEMAGGLUTININ HA1 FAB HEAVY CHAIN, ... | 著者 | Xiong, X, Corti, D, Liu, J, Pinna, D, Foglierini, M, Calder, L.J, Martin, S.R, Lin, Y.P, Walker, P.A, Collins, P.J, Monne, I, Suguitan Jr, A.L, Santos, C, Temperton, N.J, Subbarao, K, Lanzavecchia, A, Gamblin, S.J, Skehel, J.J. | 登録日 | 2015-06-01 | 公開日 | 2015-07-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Structures of Complexes Formed by H5 Influenza Hemagglutinin with a Potent Broadly Neutralizing Human Monoclonal Antibody. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
3EYJ
| Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion | 分子名称: | Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | 著者 | Russell, R.J, Kerry, P.S, Stevens, D.J, Steinahuer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. | 登録日 | 2008-10-21 | 公開日 | 2009-01-13 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion Proc.Natl.Acad.Sci.USA, 105, 2008
|
|
3EYK
| Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion | 分子名称: | 2-tert-butylbenzene-1,4-diol, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | 著者 | Russell, R.J, Kerry, P.S, Stevens, D.J, Steinhauer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. | 登録日 | 2008-10-21 | 公開日 | 2009-01-13 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion Proc.Natl.Acad.Sci.USA, 105, 2008
|
|
1TX4
| RHO/RHOGAP/GDP(DOT)ALF4 COMPLEX | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, P50-RHOGAP, ... | 著者 | Rittinger, K, Walker, P.A, Smerdon, S.J, Gamblin, S.J. | 登録日 | 1997-07-29 | 公開日 | 1998-09-16 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue. Nature, 389, 1997
|
|
3EYM
| Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion | 分子名称: | 2-tert-butylbenzene-1,4-diol, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | 著者 | Russell, R.J, Kerry, P.S, Stevens, D.A, Steinhauer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. | 登録日 | 2008-10-21 | 公開日 | 2009-01-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion Proc.Natl.Acad.Sci.USA, 105, 2008
|
|
3T4N
| Structure of the regulatory fragment of Saccharomyces cerevisiae AMPK in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Carbon catabolite-derepressing protein kinase, Nuclear protein SNF4, ... | 著者 | Mayer, F.V, Heath, R, Underwood, E, Sanders, M.J, Carmena, D, McCartney, R, Leiper, F.C, Xiao, B, Jing, C, Walker, P.A, Haire, L.F, Ogrodowicz, R, Martin, S.R, Schmdit, M.C, Gamblin, S.J, Carling, D. | 登録日 | 2011-07-26 | 公開日 | 2011-11-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase. Cell Metab, 14, 2011
|
|
3TE5
| structure of the regulatory fragment of sacchromyces cerevisiae ampk in complex with NADH | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Carbon catabolite-derepressing protein kinase, Nuclear protein SNF4, ... | 著者 | Mayer, F.V, Heath, R, Underwood, E, Sanders, M.J, Carmena, D, McCartney, R, Leiper, F.C, Xiao, B, Jing, C, Walker, P.A, Haire, L.F, Ogrodowicz, R, Martin, S.R, Schmidt, M.C, Gamblin, S.J, Carling, D. | 登録日 | 2011-08-12 | 公開日 | 2011-11-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase. Cell Metab, 14, 2011
|
|
3TDH
| Structure of the regulatory fragment of sccharomyces cerevisiae AMPK in complex with AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, Carbon catabolite-derepressing protein kinase, Nuclear protein SNF4, ... | 著者 | Mayer, F.V, Heath, R, Underwood, E, Sanders, M.J, Carmena, D, McCartney, R, Leiper, F.C, Xiao, B, Jing, C, Walker, P.A, Haire, L.F, Ogrodowicz, R, Martin, S.R, Schmidt, M.C, Gamblin, S.J, Carling, D. | 登録日 | 2011-08-11 | 公開日 | 2011-11-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase. Cell Metab, 14, 2011
|
|
1XQH
| Crystal structure of a ternary complex of the methyltransferase SET9 (also known as SET7/9) with a P53 peptide and SAH | 分子名称: | 9-mer peptide from tumor protein p53, Histone-lysine N-methyltransferase, H3 lysine-4 specific, ... | 著者 | Chuikov, S, Kurash, J.K, Wilson, J.R, Xiao, B, Justin, N, Ivanov, G.S, McKinney, K, Tempst, P, Prives, C, Gamblin, S.J, Barlev, N.A, Reinberg, D. | 登録日 | 2004-10-12 | 公開日 | 2004-11-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Regulation of p53 activity through lysine methylation Nature, 432, 2004
|
|
2AIO
| Metallo beta lactamase L1 from Stenotrophomonas maltophilia complexed with hydrolyzed moxalactam | 分子名称: | (2R)-2-((R)-CARBOXY{[CARBOXY(4-HYDROXYPHENYL)ACETYL]AMINO}METHOXYMETHYL)-5-METHYLENE-5,6-DIHYDRO-2H-1,3-OXAZINE-4-CARBO XYLIC ACID, Metallo-beta-lactamase L1, SULFATE ION, ... | 著者 | Spencer, J, Read, J, Sessions, R.B, Howell, S, Blackburn, G.M, Gamblin, S.J. | 登録日 | 2005-07-30 | 公開日 | 2005-10-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Antibiotic Recognition by Binuclear Metallo-beta-Lactamases Revealed by X-ray Crystallography J.Am.Chem.Soc., 127, 2005
|
|
5ISO
| STRUCTURE OF FULL LENGTH HUMAN AMPK (NON-PHOSPHORYLATED AT T-LOOP) IN COMPLEX WITH A SMALL MOLECULE ACTIVATOR, A BENZIMIDAZOLE DERIVATIVE (991) | 分子名称: | 5'-AMP-activated protein kinase catalytic subunit alpha-2, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... | 著者 | Xiao, B, Hubbard, J.A, Gamblin, S.J. | 登録日 | 2016-03-15 | 公開日 | 2017-03-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | STRUCTURE OF FULL LENGTH HUMAN AMPK (NON-PHOSPHORYLATED AT T-LOOP) IN COMPLEX WITH A SMALL MOLECULE ACTIVATOR, A BENZIMIDAZOLE DERIVATIVE (991) To Be Published
|
|
5JW5
| Structure of MEDI8852 Fab Fragment | 分子名称: | MEDI8852 Heavy chain, MEDI8852 Light chain, PHOSPHATE ION | 著者 | Neu, U, Collins, P.J, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J. | 登録日 | 2016-05-11 | 公開日 | 2016-08-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes. Cell, 166, 2016
|
|
5JW3
| Structure of MEDI8852 Fab Fragment in Complex with H7 HA | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | 著者 | Collins, P.J, Neu, U, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J. | 登録日 | 2016-05-11 | 公開日 | 2016-08-03 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.75 Å) | 主引用文献 | Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes. Cell, 166, 2016
|
|
5JW4
| Structure of MEDI8852 Fab Fragment in Complex with H5 HA | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | 著者 | Neu, U, Collins, P.J, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J. | 登録日 | 2016-05-11 | 公開日 | 2016-08-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes. Cell, 166, 2016
|
|
1MXE
| Structure of the Complex of Calmodulin with the Target Sequence of CaMKI | 分子名称: | CALCIUM ION, Calmodulin, Target Sequence of rat Calmodulin-Dependent Protein Kinase I | 著者 | Clapperton, J.A, Martin, S.R, Smerdon, S.J, Gamblin, S.J, Bayley, P.M. | 登録日 | 2002-10-02 | 公開日 | 2002-12-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of the Complex
of Calmodulin with the Target
Sequence of Calmodulin-Dependent
Protein Kinase I: Studies of the
Kinase Activation Mechanism Biochemistry, 41, 2002
|
|
7R10
| Dissociated S1 domain of Alpha Variant SARS-CoV-2 Spike bound to ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | 著者 | Benton, D.J, Wrobel, A.G, Gamblin, S.J. | 登録日 | 2022-02-02 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Evolution of the SARS-CoV-2 spike protein in the human host. Nat Commun, 13, 2022
|
|
7R15
| |
7R1A
| Furin Cleaved Alpha Variant SARS-CoV-2 Spike in complex with 3 ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Benton, D.J, Wrobel, A.G, Gamblin, S.J. | 登録日 | 2022-02-02 | 公開日 | 2022-03-02 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Evolution of the SARS-CoV-2 spike protein in the human host. Nat Commun, 13, 2022
|
|
7R18
| Mink Variant SARS-CoV-2 Spike in Closed conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Benton, D.J, Wrobel, A.G, Gamblin, S.J. | 登録日 | 2022-02-02 | 公開日 | 2022-03-09 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Evolution of the SARS-CoV-2 spike protein in the human host. Nat Commun, 13, 2022
|
|
7R17
| |