8GRX
 
 | | APOE4 receptor in complex with APOE4 NTD | | 分子名称: | Apolipoprotein E, Leukocyte immunoglobulin-like receptor subfamily A member 6 | | 著者 | Zhou, J, Wang, Y, Huang, G, Shi, Y. | | 登録日 | 2022-09-02 | | 公開日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | LilrB3 is a putative cell surface receptor of APOE4.
Cell Res., 33, 2023
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2DXC
 | | Recombinant thiocyanate hydrolase, fully-matured form | | 分子名称: | COBALT (III) ION, L(+)-TARTARIC ACID, Thiocyanate hydrolase subunit alpha, ... | | 著者 | Arakawa, T, Kawano, Y, Katayama, Y, Yohda, M, Odaka, M. | | 登録日 | 2006-08-25 | | 公開日 | 2007-08-28 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Basis for Catalytic Activation of Thiocyanate Hydrolase Involving Metal-Ligated Cysteine Modification
J.Am.Chem.Soc., 131, 2009
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2QDW
 | | Structure of Cu(I) form of the M51A mutant of amicyanin | | 分子名称: | Amicyanin, COPPER (I) ION, PHOSPHATE ION | | 著者 | Ma, J.K, Wang, Y, Carrell, C.J, Mathews, F.S, Davidson, V.L. | | 登録日 | 2007-06-21 | | 公開日 | 2007-12-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (0.92 Å) | | 主引用文献 | A single methionine residue dictates the kinetic mechanism of interprotein electron transfer from methylamine dehydrogenase to amicyanin.
Biochemistry, 46, 2007
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8JIN
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1HYV
 | | HIV INTEGRASE CORE DOMAIN COMPLEXED WITH TETRAPHENYL ARSONIUM | | 分子名称: | CHLORIDE ION, INTEGRASE, SULFATE ION, ... | | 著者 | Molteni, V, Greenwald, J, Rhodes, D, Hwang, Y, Kwiatkowski, W, Bushman, F.D, Siegel, J.S, Choe, S. | | 登録日 | 2001-01-22 | | 公開日 | 2001-04-04 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain.
Acta Crystallogr.,Sect.D, 57, 2001
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1HYZ
 | | HIV INTEGRASE CORE DOMAIN COMPLEXED WITH A DERIVATIVE OF TETRAPHENYL ARSONIUM. | | 分子名称: | (3,4-DIHYDROXY-PHENYL)-TRIPHENYL-ARSONIUM, CHLORIDE ION, INTEGRASE, ... | | 著者 | Molteni, V, Greenwald, J, Rhodes, D, Hwang, Y, Kwiatkowski, W, Bushman, F.D, Siegel, J.S, Choe, S. | | 登録日 | 2001-01-22 | | 公開日 | 2001-04-04 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain.
Acta Crystallogr.,Sect.D, 57, 2001
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7V3L
 | | MERS S ectodomain trimer in complex with neutralizing antibody 6516 | | 分子名称: | Spike glycoprotein, antibody H, antibody L | | 著者 | Wang, X, Zhao, J, Wang, Z, Wang, Y, Zeng, J. | | 登録日 | 2021-08-10 | | 公開日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | MERS S ectodomain trimer in complex with neutralizing antibody 6516
to be published
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2POG
 | | Benzopyrans as Selective Estrogen Receptor b Agonists (SERBAs). Part 2: Structure Activity Relationship Studies on the Benzopyran Scaffold. | | 分子名称: | (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL, Estrogen receptor | | 著者 | Richardson, T.I, Norman, B.H, Lugar, C.W, Jones, S.A, Wang, Y, Durbin, J.D, Krishnan, V, Dodge, J.A. | | 登録日 | 2007-04-26 | | 公開日 | 2007-09-11 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 2: structure-activity relationship studies on the benzopyran scaffold.
Bioorg.Med.Chem.Lett., 17, 2007
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5XG7
 | | Galectin-13/Placental Protein 13 crystal structure | | 分子名称: | Galactoside-binding soluble lectin 13 | | 著者 | Su, J.Y, Wang, Y. | | 登録日 | 2017-04-12 | | 公開日 | 2018-01-31 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Galectin-13, a different prototype galectin, does not bind beta-galacto-sides and forms dimers via intermolecular disulfide bridges between Cys-136 and Cys-138
Sci Rep, 8, 2018
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2IS3
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2QDV
 | | Structure of the Cu(II) form of the M51A mutant of amicyanin | | 分子名称: | Amicyanin, COPPER (II) ION, PHOSPHATE ION | | 著者 | Carrell, C.J, Ma, J.K, Wang, Y, Davidson, V.L, Mathews, F.S. | | 登録日 | 2007-06-21 | | 公開日 | 2007-12-11 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (0.89 Å) | | 主引用文献 | A single methionine residue dictates the kinetic mechanism of interprotein electron transfer from methylamine dehydrogenase to amicyanin.
Biochemistry, 46, 2007
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2QE4
 | | Estrogen receptor alpha ligand-binding domain in complex with a benzopyran agonist | | 分子名称: | (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL, Estrogen receptor | | 著者 | Norman, B.H, Richardson, T.I, Dodge, J.A, Pfeifer, L.A, Durst, G.L, Wang, Y, Durbin, J.D, Krishnan, V, Dinn, S.R, Liu, S.Q, Reilly, J.E, Ryter, K.T. | | 登録日 | 2007-06-22 | | 公開日 | 2007-09-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 4: Functionalization of the benzopyran A-ring.
Bioorg.Med.Chem.Lett., 17, 2007
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2F96
 | | 2.1 A crystal structure of Pseudomonas aeruginosa rnase T (Ribonuclease T) | | 分子名称: | MAGNESIUM ION, Ribonuclease T | | 著者 | Zheng, H, Chruszcz, M, Cymborowski, M, Wang, Y, Gorodichtchenskaia, E, Skarina, T, Guthrie, J, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-12-05 | | 公開日 | 2006-02-14 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Crystal Structure of RNase T, an Exoribonuclease Involved in tRNA Maturation and End Turnover.
Structure, 15, 2007
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6M0X
 | | Crystal structure of Streptococcus thermophilus Cas9 in complex with AGGA PAM | | 分子名称: | BARIUM ION, CRISPR-associated endonuclease Cas9 1, DNA (28-MER), ... | | 著者 | Zhang, Y, Zhang, H, Xu, X, Wang, Y, Chen, W, Wang, Y, Wu, Z, Tang, N, Wang, Y, Zhao, S, Gan, J, Ji, Q. | | 登録日 | 2020-02-23 | | 公開日 | 2020-09-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.561 Å) | | 主引用文献 | Catalytic-state structure and engineering of Streptococcus thermophilus Cas9
Nat Catal, 2020
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6M0W
 | | Crystal structure of Streptococcus thermophilus Cas9 in complex with the AGAA PAM | | 分子名称: | CRISPR-associated endonuclease Cas9 1, DNA (28-MER), DNA (5'-D(*AP*AP*AP*GP*AP*AP*GP*C)-3'), ... | | 著者 | Zhang, Y, Zhang, H, Xu, X, Wang, Y, Chen, W, Wang, Y, Wu, Z, Tang, N, Wang, Y, Zhao, S, Gan, J, Ji, Q. | | 登録日 | 2020-02-23 | | 公開日 | 2020-09-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Catalytic-state structure and engineering of Streptococcus thermophilus Cas9
Nat Catal, 2020
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7V5K
 | | MERS S ectodomain trimer in complex with neutralizing antibody 0722 (state 1) | | 分子名称: | 0722 H, 0722 L, Spike glycoprotein | | 著者 | Wang, X, Zhao, J, Wang, Z, Zeng, J, Zhang, S, Wang, Y. | | 登録日 | 2021-08-17 | | 公開日 | 2022-08-24 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | MERS S ectodomain trimer in complex with neutralizing antibody 0722 (state 1)
to be published
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1WMS
 | | High resolution crystal structure of human Rab9 GTPase: a novel antiviral drug target | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-9A | | 著者 | Chen, L, DiGiammarino, E, Zhou, X.E, Wang, Y, Toh, D, Hodge, T.W, Meehan, E.J. | | 登録日 | 2004-07-16 | | 公開日 | 2004-09-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | High resolution crystal structure of human Rab9 GTPase: A novel antiviral drug target
J.Biol.Chem., 279, 2004
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7V5J
 | | MERS S ectodomain trimer in complex with neutralizing antibody 0722(state 2) | | 分子名称: | 0722 H, 0722 L, Spike glycoprotein | | 著者 | Wang, X, Zhao, J, Wang, Z, Zeng, J, Zhang, S, Wang, Y. | | 登録日 | 2021-08-17 | | 公開日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | MERS S ectodomain trimer in complex with neutralizing antibody 0722(state 2)
to be published
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7V6N
 | | MERS S ectodomain trimer in complex with neutralizing antibody 111 state1 | | 分子名称: | 111 H, 111 L, Spike glycoprotein | | 著者 | Wang, X, Zhao, J, Wang, Z, Zeng, J, Zhang, S, Wang, Y. | | 登録日 | 2021-08-20 | | 公開日 | 2022-09-14 | | 実験手法 | ELECTRON MICROSCOPY (3.99 Å) | | 主引用文献 | MERS S ectodomain trimer in complex with neutralizing antibody 111 state1
to be published
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7V6O
 | | MERS S ectodomain trimer in complex with neutralizing antibody 111 (state 2) | | 分子名称: | 111 H, 111 L, Spike glycoprotein | | 著者 | Wang, X, Zhao, J, Wang, Z, Zeng, J, Zhang, S, Wang, Y. | | 登録日 | 2021-08-20 | | 公開日 | 2022-09-28 | | 実験手法 | ELECTRON MICROSCOPY (4.56 Å) | | 主引用文献 | MERS S ectodomain trimer in complex with neutralizing antibody 111 (state 2)
to be published
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6M0V
 | | Crsytal structure of streptococcus thermophilus Cas9 in complex with the GGAA PAM | | 分子名称: | BARIUM ION, CRISPR-associated endonuclease Cas9 1, DNA (28-MER), ... | | 著者 | Zhang, Y, Zhang, H, Xu, X, Wang, Y, Chen, W, Wang, Y, Wu, Z, Tang, N, Wang, Y, Zhao, S, Gan, J, Ji, Q. | | 登録日 | 2020-02-22 | | 公開日 | 2020-09-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Catalytic-state structure and engineering of Streptococcus thermophilus Cas9
Nat Catal, 2020
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1DX5
 | | Crystal structure of the thrombin-thrombomodulin complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FORMIC ACID, ... | | 著者 | Fuentes-Prior, P, Iwanaga, Y, Huber, R, Pagila, R, Rumennik, G, Seto, M, Morser, J, Light, D.R, Bode, W. | | 登録日 | 1999-12-20 | | 公開日 | 2000-04-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Basis for the Anticoagulant Activity of the Thrombin-Thrombomodulin Complex
Nature, 404, 2000
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6KFP
 | | Crystal structure of MavC ternary complex | | 分子名称: | MavC, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 N | | 著者 | Mu, Y, Wang, Y, Han, Y, Li, D, Feng, Y. | | 登録日 | 2019-07-08 | | 公開日 | 2020-04-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | | 主引用文献 | Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC.
Nat Commun, 11, 2020
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3IGC
 | | Smallpox virus topoisomerase-DNA transition state | | 分子名称: | 5'-D(*AP*TP*TP*CP*C)-3', 5'-D(*CP*GP*GP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*GP*TP*GP*TP*CP*GP*CP*CP*CP*TP*T)-3', ... | | 著者 | Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D. | | 登録日 | 2009-07-27 | | 公開日 | 2010-03-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Insights from the Structure of a Smallpox Virus Topoisomerase-DNA Transition State Mimic.
Structure, 18, 2010
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1X6N
 | | Crystal structure of S. marcescens chitinase A mutant W167A in complex with allosamidin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-allopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-allopyranose, ALLOSAMIZOLINE, Chitinase A | | 著者 | Aronson Jr, N.N, Halloran, B.A, Alexyev, M.F, Zhou, X.E, Wang, Y, Meehan, E.J, Chen, L. | | 登録日 | 2004-08-11 | | 公開日 | 2005-07-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Muation of Trp167 at the -3 subsite of the chitin-binding cleft of S. marcescens chitinase A causes enhanced transglycosylation
To be Published
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