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7VJN
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Crystal structure of anti-CRISPR-associated protein Aca1 in Pseudomonas phage JBD30
分子名称: anti-CRISPR-associated protein Aca1
著者Liu, Y.H, Zhang, L.S, Wu, B.X, Huang, H.D.
登録日2021-09-28
公開日2021-10-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Structural basis for anti-CRISPR repression mediated by bacterial operon proteins Aca1 and Aca2.
J.Biol.Chem., 297, 2021
7VJM
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BU of 7vjm by Molmil
Aca1 in complex with 19bp palindromic DNA substrate
分子名称: DNA (5'-D(*AP*TP*TP*AP*GP*GP*CP*AP*CP*AP*TP*TP*GP*TP*GP*CP*CP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*GP*GP*CP*AP*CP*AP*AP*TP*GP*TP*GP*CP*CP*TP*AP*A)-3'), anti-CRISPR-associated protein Aca1
著者Liu, Y.H, Zhang, L.S, Wu, B.X, Huang, H.D.
登録日2021-09-28
公開日2021-10-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for anti-CRISPR repression mediated by bacterial operon proteins Aca1 and Aca2.
J.Biol.Chem., 297, 2021
7VJP
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BU of 7vjp by Molmil
Selenomethionine-derived Pectobacterium phage ZF40 apo-Aca2
分子名称: SULFATE ION, anti-CRISPR-associated protein Aca2
著者Liu, Y.H, Zhang, L.S, Wu, B.X, Huang, H.D.
登録日2021-09-28
公開日2021-10-20
最終更新日2022-02-02
実験手法X-RAY DIFFRACTION (1.594 Å)
主引用文献Structural basis for anti-CRISPR repression mediated by bacterial operon proteins Aca1 and Aca2.
J.Biol.Chem., 297, 2021
4DV9
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BU of 4dv9 by Molmil
Crystal structure of BACE1 with its inhibitor
分子名称: Beta-secretase 1, METHYL (2S)-1-[(2R,5S,8S,12S,13S,16S,19S,22S)-16-(3-AMINO-3-OXOPROPYL)-2,13-DIBENZYL-12,22-DIHYDROXY-3,5,17-TRIMETHYL-8-(2-METHYLPROPYL)-4,7,10,15,18,21-HEXAOXO-19-(PROPAN-2-YL)-3,6,9,14,17,20-HEXAAZATRICOSAN-1-OYL]PYRROLIDINE-2-CARBOXYLATE (NON-PREFERRED NAME), SULFATE ION
著者Xu, Y.C, Chen, W.Y, Li, L, Chen, T.T.
登録日2012-02-23
公開日2013-01-16
最終更新日2021-09-15
実験手法X-RAY DIFFRACTION (2.076 Å)
主引用文献Cyanobacterial Peptides as a Prototype for the Design of Potent beta-Secretase Inhibitors and the Development of Selective Chemical Probes for Other Aspartic Proteases
J.Med.Chem., 55, 2012
5XZ3
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BU of 5xz3 by Molmil
The X-ray structure of Apis mellifera PGRP-SA
分子名称: Peptidoglycan-recognition protein, SULFATE ION
著者Liu, Y.J, Huang, J.X, Zhao, X.M, An, J.D.
登録日2017-07-11
公開日2018-07-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal structure of peptidoglycan recognition protein SA in Apis mellifera (Hymenoptera: Apidae).
Protein Sci., 27, 2018
7DV8
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BU of 7dv8 by Molmil
The crystal structure of rice immune receptor RGA5-HMA2.
分子名称: Disease resistance protein RGA5
著者Zhang, X, Liu, J.F.
登録日2021-01-12
公開日2021-10-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.447 Å)
主引用文献A designer rice NLR immune receptor confers resistance to the rice blast fungus carrying noncorresponding avirulence effectors.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CKK
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BU of 7ckk by Molmil
Structural complex of FTO bound with Dac51
分子名称: 2-{[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino}-N-hydroxybenzamide, Alpha-ketoglutarate-dependent dioxygenase FTO, N-OXALYLGLYCINE
著者Yang, C, Gan, J.
登録日2020-07-17
公開日2021-07-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance.
Cell Metab., 33, 2021
6LCG
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BU of 6lcg by Molmil
Structure of D-carbamoylase mutant from Nitratireductor indicus
分子名称: DI(HYDROXYETHYL)ETHER, N-carbamoyl-D-amino-acid hydrolase
著者Liu, Y.F, Ni, Y, Xu, G.C, Dai, W.
登録日2019-11-18
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure-Guided Engineering of D-Carbamoylase Reveals a Key Loop at Substrate Entrance Tunnel
Acs Catalysis, 10, 2020
8H08
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BU of 8h08 by Molmil
SARS-CoV-2 BA.1 variants S ectodomain trimer in complex with neutralizing antibody 10-5B and 6-2C
分子名称: 10-5B H chain, 10-5B L chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wang, X, Wang, Z.
登録日2022-09-28
公開日2023-05-31
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Inactivated vaccine-elicited potent antibodies can broadly neutralize SARS-CoV-2 circulating variants.
Nat Commun, 14, 2023
8H07
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BU of 8h07 by Molmil
SARS-CoV-2 BA.4 variants S ectodomain trimer in complex with neutralizing antibody 10-5B and 6-2C
分子名称: 10-5B H chain, 10-5B L chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wang, X, Wang, Z.
登録日2022-09-28
公開日2023-05-31
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Inactivated vaccine-elicited potent antibodies can broadly neutralize SARS-CoV-2 circulating variants.
Nat Commun, 14, 2023
6LEI
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BU of 6lei by Molmil
Structure of D-carbamoylase from Nitratireductor indicus
分子名称: 1,2-ETHANEDIOL, N-carbamoyl-D-amino-acid hydrolase
著者Ni, Y, Liu, Y.F, Xu, G.C.
登録日2019-11-25
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-Guided Engineering of D-Carbamoylase Reveals a Key Loop at Substrate Entrance Tunnel
Acs Catalysis, 10, 2020
6LED
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BU of 6led by Molmil
Structure of D-carbamoylase mutant from Nitratireductor indicus
分子名称: 1,2-ETHANEDIOL, N-carbamoyl-D-amino-acid hydrolase
著者Ni, Y, Liu, Y.F, Xu, G.C.
登録日2019-11-25
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structure-Guided Engineering of D-Carbamoylase Reveals a Key Loop at Substrate Entrance Tunnel
Acs Catalysis, 10, 2020
6LE2
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BU of 6le2 by Molmil
Structure of D-carbamoylase mutant from Nitratireductor indicus
分子名称: 1,2-ETHANEDIOL, GLYCEROL, N-carbamoyl-D-amino-acid hydrolase
著者Ni, Y, Liu, Y.F, Xu, G.C, Dai, W.
登録日2019-11-23
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structure-Guided Engineering of D-Carbamoylase Reveals a Key Loop at Substrate Entrance Tunnel
Acs Catalysis, 10, 2020
3WKR
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BU of 3wkr by Molmil
Crystal structure of the SepCysS-SepCysE complex from Methanocaldococcus jannaschii
分子名称: O-phospho-L-seryl-tRNA:Cys-tRNA synthase, Uncharacterized protein MJ1481
著者Nakazawa, Y, Asano, N, Nakamura, A, Yao, M.
登録日2013-10-30
公開日2014-07-16
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献Ancient translation factor is essential for tRNA-dependent cysteine biosynthesis in methanogenic archaea.
Proc.Natl.Acad.Sci.USA, 111, 2014
3WKS
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BU of 3wks by Molmil
Crystal structure of the SepCysS-SepCysE N-terminal domain complex from
分子名称: O-phospho-L-seryl-tRNA:Cys-tRNA synthase, Uncharacterized protein MJ1481
著者Nakazawa, Y, Asano, N, Nakamura, A, Yao, M.
登録日2013-10-30
公開日2014-07-30
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (3.029 Å)
主引用文献Ancient translation factor is essential for tRNA-dependent cysteine biosynthesis in methanogenic archaea.
Proc.Natl.Acad.Sci.USA, 111, 2014
3S2X
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BU of 3s2x by Molmil
Structure of acetyl-Coenzyme A synthase Alpha subunit C-terminal domain
分子名称: NICKEL (II) ION, acetyl-CoA synthase subunit alpha
著者Li, P.
登録日2011-05-17
公開日2011-07-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Insights into the Mechanistic Role of the [Fe(4) S(4) ] Cubane in the A-Cluster {[Fe(4) S(4) ]-(SR)-[Ni(p) Ni(d) ]} of Acetyl-Coenzyme A Synthase.
Chembiochem, 12, 2011
6LHH
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BU of 6lhh by Molmil
Crystal structure of chicken 8mer-BF2*1501
分子名称: ARG-ARG-ARG-GLU-GLN-THR-ASP-TYR, Beta-2-microglobulin, MHC class I
著者Liu, Y.J, Xia, C.
登録日2019-12-08
公開日2020-12-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献The Combination of CD8 alpha alpha and Peptide-MHC-I in a Face-to-Face Mode Promotes Chicken gamma delta T Cells Response.
Front Immunol, 11, 2020
6LHF
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BU of 6lhf by Molmil
Crystal structure of chicken cCD8aa/pBF2*15:01
分子名称: Beta-2-microglobulin, CD8 alpha chain, MHC class I, ...
著者Liu, Y.J, Xia, C.
登録日2019-12-08
公開日2020-12-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Combination of CD8 alpha alpha and Peptide-MHC-I in a Face-to-Face Mode Promotes Chicken gamma delta T Cells Response.
Front Immunol, 11, 2020
3UQP
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BU of 3uqp by Molmil
Crystal structure of Bace1 with its inhibitor
分子名称: Beta-secretase 1, METHYL (2R)-1-[(6S,9S,12S,13S,17S,20S,23R)-9-(3-AMINO-3-OXOPROPYL)-12,23-DIBENZYL-13-HYDROXY-2,2,8,20,22-PENTAMETHYL-17-(2-METHYLPROPYL)-4,7,10,15,18,21,24-HEPTAOXO-6-(PROPAN-2-YL)-3-OXA-5,8,11,16,19,22-HEXAAZATETRACOSAN-24-YL]PYRROLIDINE-2-CARBOXYLATE, SULFATE ION
著者Chen, T.T, Chen, W.Y, Li, L, Xu, Y.C.
登録日2011-11-21
公開日2012-11-21
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Cyanobacterial Peptides as a Prototype for the Design of Potent beta-Secretase Inhibitors and the Development of Selective Chemical Probes for Other Aspartic Proteases
J.Med.Chem., 55, 2012
6LHG
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BU of 6lhg by Molmil
Crystal structure of chicken cCD8aa/pBF2*04:01
分子名称: Beta-2-microglobulin, CD8 alpha chain, IE8 peptide, ...
著者Liu, Y.J, Xia, C.
登録日2019-12-08
公開日2020-12-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Combination of CD8 alpha alpha and Peptide-MHC-I in a Face-to-Face Mode Promotes Chicken gamma delta T Cells Response.
Front Immunol, 11, 2020
3UQR
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BU of 3uqr by Molmil
Crystal structure of BACE1 with its inhibitor
分子名称: Beta-secretase 1, METHYL (2S)-1-[(2R,5S,8S,12S,13S)-2,13-DIBENZYL-12-HYDROXY-3,5-DIMETHYL-15-(3-[METHYL(METHYLSULFONYL)AMINO]-5-{[(1R)-1-PHENYLETHYL]CARBAMOYL}PHENYL)-8-(2-METHYLPROPYL)-4,7,10,15-TETRAOXO-3,6,9,14-TETRAAZAPENTADECAN-1-OYL]PYRROLIDINE-2-CARBOXYLATE
著者Chen, T.T, Chen, W.Y, Li, L, Xu, Y.C.
登録日2011-11-21
公開日2012-11-21
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.056 Å)
主引用文献Cyanobacterial Peptides as a Prototype for the Design of Potent beta-Secretase Inhibitors and the Development of Selective Chemical Probes for Other Aspartic Proteases
J.Med.Chem., 55, 2012
3VFN
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BU of 3vfn by Molmil
crystal structure of HLA B*3508LPEP151A, HLA mutant Ala151
分子名称: Beta-2-microglobulin, LPEP peptide from EBV, LPEPLPQGQLTAY, ...
著者Liu, Y, Rossjohn, J, Gras, S.
登録日2012-01-10
公開日2012-03-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
5VNP
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X-ray crystal structure of Halotag bound to the P1 benzoxadiazole fluorogenic ligand
分子名称: CHLORIDE ION, Haloalkane dehalogenase, N-{2-[2-(hexyloxy)ethoxy]ethyl}-N~2~-methyl-N~2~-{[7-(methylamino)-2,1,3-benzoxadiazol-4-yl]sulfonyl}glycinamide
著者Dunham, N.P, Boal, A.K.
登録日2017-05-01
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献AgHalo: A Facile Fluorogenic Sensor to Detect Drug-Induced Proteome Stress.
Angew. Chem. Int. Ed. Engl., 56, 2017
4QLI
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BU of 4qli by Molmil
A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation
分子名称: 14-3-3 protein sigma, GLYCEROL, MAGNESIUM ION, ...
著者Bier, D, Ottmann, C.
登録日2014-06-12
公開日2015-06-17
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation
To be Published
7X2H
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BU of 7x2h by Molmil
Crystal structure of SARS-CoV-2 spike receptor-binding domain bound with 6-2C Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-2C H chain, 6-2C L chain, ...
著者Wang, X, Wang, Z.
登録日2022-02-25
公開日2023-03-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Inactivated vaccine-elicited potent antibodies can broadly neutralize SARS-CoV-2 circulating variants.
Nat Commun, 14, 2023

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