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3FDE
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BU of 3fde by Molmil
Mouse UHRF1 SRA domain bound with hemi-methylated CpG DNA, crystal structure in space group C222(1) at 1.4 A resolution
分子名称: 1,2-ETHANEDIOL, 5'-D(*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3', 5'-D(*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3', ...
著者Hashimoto, H, Horton, J.R, Zhang, X, Cheng, X.
登録日2008-11-25
公開日2009-01-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.
Epigenetics, 4, 2009
3F8J
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BU of 3f8j by Molmil
Mouse UHRF1 SRA domain bound with hemi-methylated CpG, crystal structure in space group C222(1)
分子名称: 5'-D(*DCP*DCP*DAP*DTP*DGP*(5CM)P*DGP*DCP*DTP*DGP*DAP*DC)-3', 5'-D(*DGP*DTP*DCP*DAP*DGP*DCP*DGP*DCP*DAP*DTP*DGP*DG)-3', E3 ubiquitin-protein ligase UHRF1, ...
著者Hashimoto, H, Horton, J.R, Zhang, X, Cheng, X.
登録日2008-11-12
公開日2009-01-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.
Epigenetics, 4, 2009
3SVM
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BU of 3svm by Molmil
Human MPP8 - human DNMT3AK47me2 peptide
分子名称: DNA (cytosine-5)-methyltransferase 3A, M-phase phosphoprotein 8
著者Chang, Y, Horton, J.R, Zhang, X, Cheng, X.
登録日2011-07-12
公開日2011-11-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Nat Commun, 2, 2011
4PBB
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BU of 4pbb by Molmil
The 5-Hydroxymethylcytosine-Specific Restriction Enzyme AbaSI
分子名称: SULFATE ION, Uncharacterized protein AbaSI
著者Horton, J.R, Cheng, X.
登録日2014-04-11
公開日2014-06-25
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.46 Å)
主引用文献Structure of 5-hydroxymethylcytosine-specific restriction enzyme, AbaSI, in complex with DNA.
Nucleic Acids Res., 42, 2014
4RTS
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BU of 4rts by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with AdoMet and a 5-bp non-canonical site (GTCTA)
分子名称: DNA (5'-D(*AP*CP*TP*TP*AP*GP*AP*CP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*GP*TP*CP*TP*AP*AP*G)-3'), DNA adenine methylase, ...
著者Horton, J.R, Cheng, X.
登録日2014-11-15
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
4RTR
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BU of 4rtr by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with AdoMet and a 5-bp non-canonical site (GTTTA )
分子名称: DNA (5'-D(*AP*CP*TP*TP*AP*AP*AP*CP*TP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*GP*TP*TP*TP*AP*AP*G)-3'), DNA adenine methylase, ...
著者Horton, J.R, Cheng, X.
登録日2014-11-15
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.393 Å)
主引用文献Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
4RTO
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BU of 4rto by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with Sinefungin and with DNA Containing Proximal Pap Regulon Sequence
分子名称: DNA (5'-D(*AP*CP*GP*AP*TP*CP*TP*TP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*AP*GP*AP*TP*CP*G)-3'), DNA adenine methylase, ...
著者Horton, J.R, Cheng, X.
登録日2014-11-15
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
3SWC
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BU of 3swc by Molmil
GLP (G9a-like protein) SET domain in complex with Dnmt3aK44me2 peptide
分子名称: DNA (cytosine-5)-methyltransferase 3A, Histone-lysine N-methyltransferase EHMT1, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Chang, Y, Horton, J.R, Zhang, X, Cheng, X.
登録日2011-07-13
公開日2011-11-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.332 Å)
主引用文献MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Nat Commun, 2, 2011
4RTJ
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BU of 4rtj by Molmil
A non-cognate complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with DNA and Sinefungin
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*TP*CP*TP*AP*GP*AP*TP*CP*TP*AP*GP*A)-3'), DNA adenine methylase, ...
著者Horton, J.R, Cheng, X.
登録日2014-11-15
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
4RTN
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BU of 4rtn by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with AdoHcy and with DNA Containing Proximal Pap Regulon Sequence
分子名称: DNA (5'-D(*AP*CP*GP*AP*TP*CP*TP*TP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*AP*GP*AP*TP*CP*G)-3'), DNA adenine methylase, ...
著者Horton, J.R, Cheng, X.
登録日2014-11-15
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
4RTQ
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BU of 4rtq by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with AdoHcy and a 5-bp non-canonical site (GTTTA )
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*TP*TP*AP*AP*AP*CP*TP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*GP*TP*TP*TP*AP*AP*G)-3'), ...
著者Horton, J.R, Cheng, X.
登録日2014-11-15
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
4RTM
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BU of 4rtm by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with AdoMet and with DNA Containing Distal Pap Regulon Sequence
分子名称: DNA (5'-D(*AP*CP*GP*AP*TP*CP*TP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*AP*GP*AP*TP*CP*G)-3'), DNA adenine methylase, ...
著者Horton, J.R, Cheng, X.
登録日2014-11-15
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
3SW9
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BU of 3sw9 by Molmil
GLP (G9a-like protein) SET domain in complex with Dnmt3aK44me0 peptide
分子名称: DNA (cytosine-5)-methyltransferase 3A, Histone-lysine N-methyltransferase EHMT1, SINEFUNGIN, ...
著者Chang, Y, Horton, J.R, Zhang, X, Cheng, X.
登録日2011-07-13
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Nat Commun, 2, 2011
3PU3
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BU of 3pu3 by Molmil
PHF2 Jumonji domain-NOG complex
分子名称: 1,2-ETHANEDIOL, GLYCEROL, N-OXALYLGLYCINE, ...
著者Horton, J.R, Upadhyay, A.K, Hashimoto, H, Zhang, X, Cheng, X.
登録日2010-12-03
公開日2011-01-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for human PHF2 Jumonji domain interaction with metal ions.
J.Mol.Biol., 406, 2011
4RTP
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BU of 4rtp by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with AdoMet and with DNA Containing Proximal Pap Regulon Sequence
分子名称: DNA (5'-D(*AP*CP*GP*AP*TP*CP*TP*TP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*AP*GP*AP*TP*CP*G)-3'), DNA adenine methylase, ...
著者Horton, J.R, Cheng, X.
登録日2014-11-15
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
4RTK
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BU of 4rtk by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with SAH and with DNA Containing Distal Pap Regulon Sequence
分子名称: DNA (5'-D(*AP*CP*GP*AP*TP*CP*TP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*AP*GP*AP*TP*CP*G)-3'), DNA adenine methylase, ...
著者Horton, J.R, Cheng, X.
登録日2014-11-15
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
4RTL
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BU of 4rtl by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with Sinefungin and with DNA Containing Distal Pap Regulon Sequence
分子名称: DNA (5'-D(*AP*CP*GP*AP*TP*CP*TP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*AP*GP*AP*TP*CP*G)-3'), DNA adenine methylase, ...
著者Horton, J.R, Cheng, X.
登録日2014-11-15
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.193 Å)
主引用文献Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
3RC0
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BU of 3rc0 by Molmil
Human SETD6 in complex with RelA Lys310 peptide
分子名称: 1,2-ETHANEDIOL, N-lysine methyltransferase SETD6, S-ADENOSYLMETHIONINE, ...
著者Chang, Y, Levy, D, Horton, J.R, Peng, J, Zhang, X, Gozani, O, Cheng, X.
登録日2011-03-30
公開日2011-05-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling.
Nucleic Acids Res., 39, 2011
3RDH
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BU of 3rdh by Molmil
X-ray induced covalent inhibition of 14-3-3
分子名称: 14-3-3 protein zeta/delta, 4-[(E)-{4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]pyridin-2-yl}diazenyl]benzoic acid, NICKEL (II) ION
著者Horton, J.R, Upadhyay, A.K, Fu, H, Cheng, X.
登録日2011-04-01
公開日2011-09-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor.
Proc.Natl.Acad.Sci.USA, 108, 2011
3U78
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BU of 3u78 by Molmil
E67-2 selectively inhibits KIAA1718, a human histone H3 lysine 9 Jumonji demethylase
分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, 7-[(5-aminopentyl)oxy]-N~4~-(1-benzylpiperidin-4-yl)-N~2~-[3-(dimethylamino)propyl]-6-methoxyquinazoline-2,4-diamine, ...
著者Upadhyay, A.K, Cheng, X.
登録日2011-10-13
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.689 Å)
主引用文献An Analog of BIX-01294 Selectively Inhibits a Family of Histone H3 Lysine 9 Jumonji Demethylases.
J.Mol.Biol., 416, 2012
4F7Z
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BU of 4f7z by Molmil
Conformational dynamics of exchange protein directly activated by cAMP
分子名称: GLYCEROL, Rap guanine nucleotide exchange factor 4
著者White, M.A, Tsalkova, T.N, Mei, F.C, Liu, T, Woods, V.L, Cheng, X.
登録日2012-05-16
公開日2012-10-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural analyses of a constitutively active mutant of exchange protein directly activated by cAMP.
Plos One, 7, 2012
3PVI
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BU of 3pvi by Molmil
D34G MUTANT OF PVUII ENDONUCLEASE COMPLEXED WITH COGNATE DNA SHOWS THAT ASP34 IS DIRECTLY INVOLVED IN DNA RECOGNITION AND INDIRECTLY INVOLVED IN CATALYSIS
分子名称: DNA (5'-D(*TP*GP*AP*CP*CP*AP*GP*CP*TP*GP*GP*TP*C)-3'), PROTEIN (PVUII ENDONUCLEASE)
著者Horton, J.R, Cheng, X.
登録日1998-10-09
公開日1998-10-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Asp34 of PvuII endonuclease is directly involved in DNA minor groove recognition and indirectly involved in catalysis.
J.Mol.Biol., 284, 1998
2H11
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BU of 2h11 by Molmil
Amino-terminal Truncated Thiopurine S-Methyltransferase Complexed with S-Adenosyl-L-Homocysteine
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, S-ADENOSYL-L-HOMOCYSTEINE, THIOCYANATE ION, ...
著者Horton, J.R, Cheng, X.
登録日2006-05-15
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structural basis of allele variation of human thiopurine-S-methyltransferase.
Proteins, 67, 2007
3MHT
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BU of 3mht by Molmil
TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH UNMODIFIED DNA AND ADOHCY
分子名称: DNA (5'-D(*GP*AP*TP*AP*GP*CP*GP*CP*TP*AP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*TP*AP*GP*CP*GP*CP*TP*AP*TP*C)-3'), PROTEIN (HHAI METHYLTRANSFERASE (E.C.2.1.1.73)), ...
著者O'Gara, M, Klimasauskas, S, Roberts, R.J, Cheng, X.
登録日1996-07-24
公開日1997-01-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes.
J.Mol.Biol., 261, 1996
3ICV
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BU of 3icv by Molmil
Structural Consequences of a Circular Permutation on Lipase B from Candida Antartica
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Lipase B
著者Horton, J.R, Qian, Z, Jia, D, Lutz, S, Cheng, X.
登録日2009-07-18
公開日2009-10-06
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Structural redesign of lipase B from Candida antarctica by circular permutation and incremental truncation.
J.Mol.Biol., 393, 2009

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