8I0W
 
 | | The cryo-EM structure of human C complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Coiled-coil domain-containing protein 94, ... | | 著者 | Zhan, X, Lu, Y, Shi, Y. | | 登録日 | 2023-01-11 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
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8I0R
 | | The cryo-EM structure of human Bact-I complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | | 著者 | Zhan, X, Lu, Y, Shi, Y. | | 登録日 | 2023-01-11 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
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8I0U
 | | The cryo-EM structure of human Bact-IV complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... | | 著者 | Zhan, X, Lu, Y, Shi, Y. | | 登録日 | 2023-01-11 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
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8I0T
 | | The cryo-EM structure of human Bact-III complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... | | 著者 | Zhan, X, Lu, Y, Shi, Y. | | 登録日 | 2023-01-11 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
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8I0S
 | | The cryo-EM structure of human Bact-II complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... | | 著者 | Zhan, X, Lu, Y, Shi, Y. | | 登録日 | 2023-01-11 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
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1L8Z
 | | Solution structure of HMG box 5 in human upstream binding factor | | 分子名称: | upstream binding factor 1 | | 著者 | Yang, W, Xu, Y, Wu, J, Zeng, W, Shi, Y. | | 登録日 | 2002-03-22 | | 公開日 | 2002-06-05 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and DNA binding property of the fifth HMG box domain in comparison with the first HMG box domain in human upstream binding factor
Biochemistry, 42, 2003
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6KLH
 | | Dimeric structure of Machupo virus polymerase bound to vRNA promoter | | 分子名称: | MANGANESE (II) ION, RNA (5'-R(*GP*CP*CP*UP*AP*GP*GP*AP*UP*CP*CP*AP*CP*UP*GP*UP*GP*CP*G)-3'), RNA-directed RNA polymerase L, ... | | 著者 | Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. | | 登録日 | 2019-07-30 | | 公開日 | 2020-03-18 | | 最終更新日 | 2021-12-08 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural insight into arenavirus replication machinery.
Nature, 579, 2020
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1L8Y
 | | Solution structure of HMG box 5 in human upstream binding factor | | 分子名称: | upstream binding factor 1 | | 著者 | Yang, W, Xu, Y, Wu, J, Zeng, W, Shi, Y. | | 登録日 | 2002-03-22 | | 公開日 | 2002-06-05 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and DNA binding property of the fifth HMG box domain in comparison with the first HMG box domain in human upstream binding factor
Biochemistry, 42, 2003
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1G73
 | | CRYSTAL STRUCTURE OF SMAC BOUND TO XIAP-BIR3 DOMAIN | | 分子名称: | INHIBITORS OF APOPTOSIS-LIKE PROTEIN ILP, SECOND MITOCHONDRIA-DERIVED ACTIVATOR OF CASPASES, ZINC ION | | 著者 | Wu, G, Chai, J, Suber, T.L, Wu, J.-W, Shi, Y. | | 登録日 | 2000-11-08 | | 公開日 | 2001-01-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis of IAP recognition by Smac/DIABLO.
Nature, 408, 2000
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6KLD
 | | Structure of apo Machupo virus polymerase | | 分子名称: | MANGANESE (II) ION, RNA-directed RNA polymerase L, ZINC ION | | 著者 | Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. | | 登録日 | 2019-07-30 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | Structural insight into arenavirus replication machinery.
Nature, 579, 2020
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6KLE
 | | Monomeric structure of Machupo virus polymerase bound to vRNA promoter | | 分子名称: | MANGANESE (II) ION, RNA (5'-R(*GP*CP*CP*UP*AP*GP*GP*AP*UP*CP*CP*AP*CP*UP*GP*UP*GP*CP*G)-3'), RNA-directed RNA polymerase L, ... | | 著者 | Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. | | 登録日 | 2019-07-30 | | 公開日 | 2020-03-18 | | 最終更新日 | 2021-12-08 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structural insight into arenavirus replication machinery.
Nature, 579, 2020
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1F0K
 | | THE 1.9 ANGSTROM CRYSTAL STRUCTURE OF E. COLI MURG | | 分子名称: | SULFATE ION, UDP-N-ACETYLGLUCOSAMINE-N-ACETYLMURAMYL-(PENTAPEPTIDE) PYROPHOSPHORYL-UNDECAPRENOL N-ACETYLGLUCOSAMINE TRANSFERASE | | 著者 | Ha, S, Walker, D, Shi, Y, Walker, S. | | 登録日 | 2000-05-16 | | 公開日 | 2000-07-27 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The 1.9 A crystal structure of Escherichia coli MurG, a membrane-associated glycosyltransferase involved in peptidoglycan biosynthesis.
Protein Sci., 9, 2000
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4HYD
 | | Structure of a presenilin family intramembrane aspartate protease in C2221 space group | | 分子名称: | Putative uncharacterized protein | | 著者 | Li, X, Dang, S, Yan, C, Wang, J, Shi, Y. | | 登録日 | 2012-11-13 | | 公開日 | 2012-12-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Structure of a presenilin family intramembrane aspartate protease
Nature, 493, 2013
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4HYG
 | | Structure of a presenilin family intramembrane aspartate protease in C222 space group | | 分子名称: | Putative uncharacterized protein | | 著者 | Li, X, Dang, S, Yan, C, Wang, J, Shi, Y. | | 登録日 | 2012-11-13 | | 公開日 | 2012-12-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.32 Å) | | 主引用文献 | Structure of a presenilin family intramembrane aspartate protease
Nature, 493, 2013
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4HYC
 | | Structure of a presenilin family intramembrane aspartate protease in P2 space group | | 分子名称: | Putative uncharacterized protein | | 著者 | Li, X, Dang, S, Yan, C, Wang, J, Shi, Y. | | 登録日 | 2012-11-13 | | 公開日 | 2012-12-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.95 Å) | | 主引用文献 | Structure of a presenilin family intramembrane aspartate protease
Nature, 493, 2013
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8HG1
 | | The structure of MPXV polymerase holoenzyme in replicating state | | 分子名称: | DNA (25-MER), DNA (38-MER), DNA polymerase, ... | | 著者 | Peng, Q, Xie, Y.F, Kuai, L, Wang, H, Qi, J.X, Gao, F, Shi, Y. | | 登録日 | 2022-11-13 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structure of monkeypox virus DNA polymerase holoenzyme.
Science, 379, 2023
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8HMY
 | | Cryo-EM structure of the human pre-catalytic TSEN/pre-tRNA complex | | 分子名称: | Chromosome 1 open reading frame 19, isoform CRA_a, MAGNESIUM ION, ... | | 著者 | Zhang, X, Yang, F, Zhan, X, Shi, Y. | | 登録日 | 2022-12-06 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | | 主引用文献 | Structural basis of pre-tRNA intron removal by human tRNA splicing endonuclease.
Mol.Cell, 83, 2023
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8HMZ
 | | Cryo-EM structure of the human post-catalytic TSEN/pre-tRNA complex | | 分子名称: | Chromosome 1 open reading frame 19, isoform CRA_a, MAGNESIUM ION, ... | | 著者 | Zhang, X, Yang, F, Zhan, X, Shi, Y. | | 登録日 | 2022-12-06 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis of pre-tRNA intron removal by human tRNA splicing endonuclease.
Mol.Cell, 83, 2023
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4JU0
 | | Crystal structure of 2009 pandemic influenza virus hemagglutinin mutant D225E complexed with human receptor analogue LSTc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Zhang, W, Shi, Y, Qi, J, Gao, F, Li, Q, Fan, Z, Yan, J, Gao, G.F. | | 登録日 | 2013-03-24 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.908 Å) | | 主引用文献 | Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution
J.Virol., 87, 2013
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4JTV
 | | Crystal structure of 2009 pandemic influenza virus hemagglutinin complexed with human receptor analogue LSTc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Zhang, W, Shi, Y, Qi, J, Gao, F, Li, Q, Fan, Z, Yan, J, Gao, G.F. | | 登録日 | 2013-03-24 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.997 Å) | | 主引用文献 | Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution
J.Virol., 87, 2013
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1K88
 | | Crystal structure of procaspase-7 | | 分子名称: | procaspase-7 | | 著者 | Chai, J, Wu, Q, Shiozaki, E, Srinivasa, S.M, Alnemri, E.S, Shi, Y. | | 登録日 | 2001-10-23 | | 公開日 | 2001-11-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding
Cell(Cambridge,Mass.), 107, 2001
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4JTX
 | | Crystal structure of 2009 pandemic influenza virus hemagglutinin mutant D225E | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | | 著者 | Zhang, W, Shi, Y, Qi, J, Gao, F, Li, Q, Fan, Z, Yan, J, Gao, G.F. | | 登録日 | 2013-03-24 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.997 Å) | | 主引用文献 | Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution
J.Virol., 87, 2013
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4JUH
 | | Crystal structure of 1918 pandemic influenza virus hemagglutinin mutant D225G complexed with avian receptor analogue LSTa | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Zhang, W, Shi, Y, Qi, J, Gao, F, Li, Q, Fan, Z, Yan, J, Gao, G.F. | | 登録日 | 2013-03-24 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.805 Å) | | 主引用文献 | Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution
J.Virol., 87, 2013
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4KMN
 | | Structure of cIAP1-BIR3 and inhibitor | | 分子名称: | (2S)-N-{(2R)-1-[(2R,4S)-2-{[6,6'-difluoro-3'-({(2R,4S)-4-hydroxy-1-[(2S)-2-{[(2S)-2-(methylamino)propanoyl]amino}butanoyl]pyrrolidin-2-yl}methyl)-1H,1'H-2,2'-biindol-3-yl]methyl}-4-hydroxypyrrolidin-1-yl]-1-oxobutan-2-yl}-2-(methylamino)propanamide, Baculoviral IAP repeat-containing protein 2, PHOSPHATE ION, ... | | 著者 | Li, X, Wang, J, Condon, S.M, Shi, Y. | | 登録日 | 2013-05-08 | | 公開日 | 2014-05-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.523 Å) | | 主引用文献 | Structure of cIAP1-BIR3 and inhibitor
To be Published
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4KMP
 | | Structure of XIAP-BIR3 and inhibitor | | 分子名称: | (2S,2'S)-N,N'-[(6,6'-difluoro-1H,1'H-2,2'-biindole-3,3'-diyl)bis{methanediyl[(2R,4S)-4-hydroxypyrrolidine-2,1-diyl][(2S)-1-oxobutane-1,2-diyl]}]bis[2-(methylamino)propanamide], E3 ubiquitin-protein ligase XIAP, ZINC ION | | 著者 | Li, X, Wang, J, Condon, S.M, Shi, Y. | | 登録日 | 2013-05-08 | | 公開日 | 2014-05-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure of XIAP-BIR3 and inhibitor
To be Published
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