5ABE
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![BU of 5abe by Molmil](/molmil-images/mine/5abe) | Structure of GH84 with ligand | 分子名称: | 2-[(2S,3S,4R,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)-1-pentyl-pyrrolidin-2-yl]-N-methyl-ethanamide, CALCIUM ION, O-GLCNACASE BT_4395 | 著者 | Bergeron-Brlek, M, Goodwin-Tindall, J, Cekic, N, Varghese, V, Zandberg, W.F, Shan, X, Roth, C, Chan, S, Davies, G.J, Vocadlo, D.J, Britton, R. | 登録日 | 2015-08-05 | 公開日 | 2015-11-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable Oga Inhibitors. Angew.Chem.Int.Ed.Engl., 54, 2015
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6M3W
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5ABF
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![BU of 5abf by Molmil](/molmil-images/mine/5abf) | Structure of GH84 with ligand | 分子名称: | 1,2-ETHANEDIOL, 2-[(2S,3R,4R,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)-1-pentyl-pyrrolidin-2-yl]-N-methyl-ethanamide, CALCIUM ION, ... | 著者 | Bergeron-Brlek, M, Goodwin-Tindall, J, Cekic, N, Varghese, V, Zandberg, W.F, Shan, X, Roth, C, Chan, S, Davies, G.J, Vocadlo, D.J, Britton, R. | 登録日 | 2015-08-05 | 公開日 | 2015-11-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable Oga Inhibitors. Angew.Chem.Int.Ed.Engl., 54, 2015
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7ZI4
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![BU of 7zi4 by Molmil](/molmil-images/mine/7zi4) | Cryo-EM structure of the human INO80 complex bound to a WT nucleosome | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Vance, N.R, Ayala, R, Willhoft, O, Tvardovskiy, A, McCormack, E.A, Bartke, T, Zhang, X, Wigley, D.B. | 登録日 | 2022-04-07 | 公開日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structure of the human INO80 complex bound to a WT nucleosome To Be Published
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5ABG
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![BU of 5abg by Molmil](/molmil-images/mine/5abg) | Structure of GH84 with ligand | 分子名称: | 1,2-ETHANEDIOL, 2-[(2R,3S,4R,5R)-1-[3-(4-fluorophenyl)propyl]-5-(hydroxymethyl)-3,4-bis(oxidanyl)pyrrolidin-2-yl]-N-methyl-ethanamide, CALCIUM ION, ... | 著者 | Bergeron-Brlek, M, Goodwin-Tindall, J, Cekic, N, Varghese, V, Zandberg, W.F, Shan, X, Roth, C, Chan, S, Davies, G.J, Vocadlo, D.J, Britton, R. | 登録日 | 2015-08-05 | 公開日 | 2015-11-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable Oga Inhibitors. Angew.Chem.Int.Ed.Engl., 54, 2015
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5AIY
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![BU of 5aiy by Molmil](/molmil-images/mine/5aiy) | R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 'RED' SUBSTATE, AVERAGE STRUCTURE | 分子名称: | PHENOL, PROTEIN (INSULIN) | 著者 | O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J. | 登録日 | 1998-12-29 | 公開日 | 2000-02-28 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure. J.Biomol.NMR, 16, 2000
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2KA9
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![BU of 2ka9 by Molmil](/molmil-images/mine/2ka9) | Solution structure of PSD-95 PDZ12 complexed with cypin peptide | 分子名称: | Disks large homolog 4, cypin peptide | 著者 | Wang, W.N, Weng, J.W, Zhang, X, Liu, M.L, Zhang, M.J. | 登録日 | 2008-11-03 | 公開日 | 2009-06-23 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Creating conformational entropy by increasing interdomain mobility in ligand binding regulation: a revisit to N-terminal tandem PDZ domains of PSD-95 J.Am.Chem.Soc., 131, 2009
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1DP4
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![BU of 1dp4 by Molmil](/molmil-images/mine/1dp4) | DIMERIZED HORMONE BINDING DOMAIN OF THE ATRIAL NATRIURETIC PEPTIDE RECEPTOR | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATRIAL NATRIURETIC PEPTIDE RECEPTOR A, ... | 著者 | van den Akker, F, Zhang, X, Miyagi, M, Huo, X, Misono, K.S, Yee, V.C. | 登録日 | 1999-12-23 | 公開日 | 2000-07-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the dimerized hormone-binding domain of a guanylyl-cyclase-coupled receptor. Nature, 406, 2000
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6MS7
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![BU of 6ms7 by Molmil](/molmil-images/mine/6ms7) | Peroxisome proliferator-activated receptor gamma ligand binding domain in complex with a novel selective PPAR-gamma modulator VSP-77 | 分子名称: | PGC1 LXXLL motif, Peroxisome proliferator-activated receptor gamma, {[(1S)-1-(4-chlorophenyl)octyl]oxy}acetic acid | 著者 | Yi, W, Jiang, H, Zhou, X.E, Shi, J, Zhao, G, Zhang, X, Sun, Y, Suino-Powell, K, Li, J, Li, J, Melcher, K, Xu, H.E. | 登録日 | 2018-10-16 | 公開日 | 2019-10-23 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Identification and structural insight of an effective PPAR gamma modulator with improved therapeutic index for anti-diabetic drug discovery. Chem Sci, 11, 2020
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5A9G
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![BU of 5a9g by Molmil](/molmil-images/mine/5a9g) | Manganese Superoxide Dismutase from Sphingobacterium sp. T2 | 分子名称: | MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE | 著者 | Rashid, G.M.M, Taylor, C.R, Liu, Y, Zhang, X, Rea, D, Fulop, V, Bugg, T.D.H. | 登録日 | 2015-07-21 | 公開日 | 2015-08-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Identification of Manganese Superoxide Dismutase from Sphingobacterium Sp. T2 as a Novel Bacterial Enzyme for Lignin Oxidation. Acs Chem.Biol., 10, 2015
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4TOR
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![BU of 4tor by Molmil](/molmil-images/mine/4tor) | Crystal structure of Tankyrase 1 with IWR-8 | 分子名称: | 1-[(1-acetyl-5-bromo-1H-indol-6-yl)sulfonyl]-N-ethyl-N-(3-methylphenyl)piperidine-4-carboxamide, CHLORIDE ION, Tankyrase-1, ... | 著者 | Chen, H, Zhang, X, Lum, L, Chen, C. | 登録日 | 2014-06-06 | 公開日 | 2015-05-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | 主引用文献 | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells. Mol.Cell.Biol., 35, 2015
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5C98
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![BU of 5c98 by Molmil](/molmil-images/mine/5c98) | 1.45A resolution structure of SRPN18 from Anopheles gambiae | 分子名称: | AGAP007691-PB | 著者 | Lovell, S, Battaile, K.P, Gulley, M, Zhang, X, Meekins, D.A, Gao, F.P, Michel, K. | 登録日 | 2015-06-26 | 公開日 | 2016-09-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | 1.45 angstrom resolution structure of SRPN18 from the malaria vector Anopheles gambiae. Acta Crystallogr F Struct Biol Commun, 72, 2016
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3UT4
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![BU of 3ut4 by Molmil](/molmil-images/mine/3ut4) | Structural view of a non Pfam singleton and crystal packing analysis | 分子名称: | Putative uncharacterized protein | 著者 | Cheng, C, Shaw, N, Zhang, X, Zhang, M, Ding, W, Wang, B.C, Liu, Z.J. | 登録日 | 2011-11-25 | 公開日 | 2012-03-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structural view of a non pfam singleton and crystal packing analysis. Plos One, 7, 2012
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4TOS
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![BU of 4tos by Molmil](/molmil-images/mine/4tos) | Crystal structure of Tankyrase 1 with 355 | 分子名称: | Tankyrase-1, ZINC ION, trans-N-benzyl-4-({1-[(6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl]-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl}methyl)cyclohexanecarboxamide | 著者 | Chen, H, Zhang, X, Lum, l, Chen, C. | 登録日 | 2014-06-06 | 公開日 | 2015-05-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells. Mol.Cell.Biol., 35, 2015
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3PUS
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![BU of 3pus by Molmil](/molmil-images/mine/3pus) | PHF2 Jumonji-NOG-Ni(II) | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, N-OXALYLGLYCINE, ... | 著者 | Horton, J.R, Upadhyay, A.K, Hashimoto, H, Zhang, X, Cheng, X. | 登録日 | 2010-12-06 | 公開日 | 2011-01-26 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Structural basis for human PHF2 Jumonji domain interaction with metal ions. J.Mol.Biol., 406, 2011
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1SVU
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![BU of 1svu by Molmil](/molmil-images/mine/1svu) | Structure of the Q237W mutant of HhaI DNA methyltransferase: an insight into protein-protein interactions | 分子名称: | Modification methylase HhaI, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | 著者 | Dong, A, Zhou, L, Zhang, X, Stickel, S, Roberts, R.J, Cheng, X. | 登録日 | 2004-03-30 | 公開日 | 2004-06-29 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Structure of the Q237W mutant of HhaI DNA methyltransferase: an insight into protein-protein interactions Biol.Chem., 385, 2004
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2DHR
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![BU of 2dhr by Molmil](/molmil-images/mine/2dhr) | Whole cytosolic region of ATP-dependent metalloprotease FtsH (G399L) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FtsH | 著者 | Suno, R, Niwa, H, Tsuchiya, D, Zhang, X, Yoshida, M, Morikawa, K. | 登録日 | 2006-03-24 | 公開日 | 2006-06-27 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Structure of the Whole Cytosolic Region of ATP-Dependent Protease FtsH Mol.Cell, 22, 2006
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3LOI
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![BU of 3loi by Molmil](/molmil-images/mine/3loi) | Crystal structures of Cupin superfamily BbDUF985 from Branchiostoma belcheri tsingtauense in the apo and GDP-bound forms | 分子名称: | Putative uncharacterized protein | 著者 | Zou, C.Z, Du, Y, He, Y.-X, Saren, G, Zhang, X, Chen, Y, Zhang, S.-C. | 登録日 | 2010-02-04 | 公開日 | 2010-06-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structures of the apo and GDP-bound forms of a cupin-like protein BbDUF985 from Branchiostoma belcheri tsingtauense Proteins, 2010
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3LNL
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![BU of 3lnl by Molmil](/molmil-images/mine/3lnl) | Crystal structure of Staphylococcus aureus protein SA1388 | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, UPF0135 protein SA1388, ZINC ION | 著者 | Singh, K.S, Chruszcz, M, Zhang, X, Minor, W, Zhang, H. | 登録日 | 2010-02-02 | 公開日 | 2010-03-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of a Conserved Hypothetical Protein Sa1388 from S. aureus Reveals a Capped Hexameric Toroid with Two Pii Domain Lids and a Dinuclear Metal Center. Bmc Struct.Biol., 6, 2006
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2DI4
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![BU of 2di4 by Molmil](/molmil-images/mine/2di4) | Crystal structure of the FtsH protease domain | 分子名称: | Cell division protein ftsH homolog, MERCURY (II) ION | 著者 | Suno, R, Niwa, H, Tsuchiya, D, Zhang, X, Yoshida, M, Morikawa, K. | 登録日 | 2006-03-28 | 公開日 | 2006-06-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Structure of the Whole Cytosolic Region of ATP-Dependent Protease FtsH Mol.Cell, 22, 2006
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3IG3
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5IHW
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![BU of 5ihw by Molmil](/molmil-images/mine/5ihw) | The crystal structure of SdrE from staphylococcus aureus | 分子名称: | Serine-aspartate repeat-containing protein E | 著者 | Zhang, S, Wei, J, Wu, S, Zhang, X, Luo, M, Wang, D. | 登録日 | 2016-02-29 | 公開日 | 2017-03-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | The crystal structure of SdrE from staphylococcus aureus To Be Published
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5IAY
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![BU of 5iay by Molmil](/molmil-images/mine/5iay) | NMR structure of UHRF1 Tandem Tudor Domains in a complex with Spacer peptide | 分子名称: | E3 ubiquitin-protein ligase UHRF1, Spacer | 著者 | Fang, J, Cheng, J, Wang, J, Zhang, Q, Liu, M, Gong, R, Wang, P, Zhang, X, Feng, Y, Lan, W, Gong, Z, Tang, C, Wong, J, Yang, H, Cao, C, Xu, Y. | 登録日 | 2016-02-22 | 公開日 | 2016-04-20 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition Nat Commun, 7, 2016
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3LZZ
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![BU of 3lzz by Molmil](/molmil-images/mine/3lzz) | Crystal structures of Cupin superfamily BbDUF985 from Branchiostoma belcheri tsingtauense in apo and GDP-bound forms | 分子名称: | ACETATE ION, GUANOSINE-5'-DIPHOSPHATE, Putative uncharacterized protein | 著者 | Du, Y, He, Y.-X, Saren, G, Zhang, X, Zhang, S.-C, Chen, Y, Zhou, C.-Z. | 登録日 | 2010-03-02 | 公開日 | 2010-06-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of the apo and GDP-bound forms of a cupin-like protein BbDUF985 from Branchiostoma belcheri tsingtauense Proteins, 2010
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3F8I
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![BU of 3f8i by Molmil](/molmil-images/mine/3f8i) | Mouse UHRF1 SRA domain bound with hemi-methylated CpG, crystal structure in space group P21 | 分子名称: | 5'-D(*DCP*DCP*DAP*DTP*DGP*(5CM)P*DGP*DCP*DTP*DGP*DAP*DC)-3', 5'-D(*DGP*DTP*DCP*DAP*DGP*DCP*DGP*DCP*DAP*DTP*DGP*DG)-3', E3 ubiquitin-protein ligase UHRF1 | 著者 | Hashimoto, H, Horton, J.R, Zhang, X, Cheng, X. | 登録日 | 2008-11-12 | 公開日 | 2009-01-06 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications. Epigenetics, 4, 2009
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