3JTT
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7CMW
| Complex structure of PARP1 catalytic domain with pamiparib | 分子名称: | (2R)-14-fluoro-2-methyl-6,9,10,19-tetrazapentacyclo[14.2.1.02,6.08,18.012,17]nonadeca-1(18),8,12(17),13,15-pentaen-11-one, GLYCEROL, Poly [ADP-ribose] polymerase 1 | 著者 | Feng, Y.C, Peng, H, Hong, Y, Liu, Y. | 登録日 | 2020-07-29 | 公開日 | 2020-12-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Discovery of Pamiparib (BGB-290), a Potent and Selective Poly (ADP-ribose) Polymerase (PARP) Inhibitor in Clinical Development. J.Med.Chem., 63, 2020
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8GPK
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8GP5
| Structure of X18 UFO protomer in complex with F6 Fab VHVL domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, F6 Fab VH domain, ... | 著者 | Niu, J, Xu, Y.W, Yang, B. | 登録日 | 2022-08-25 | 公開日 | 2023-08-09 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (4.05 Å) | 主引用文献 | Structures and immune recognition of Env trimers from two Asia prevalent HIV-1 CRFs. Nat Commun, 14, 2023
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8GPI
| HIV-1 Env X18 UFO in complex with 8ANC195 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 Fab heavy chain, ... | 著者 | Niu, J, Xu, Y.W, Yang, B. | 登録日 | 2022-08-26 | 公開日 | 2023-08-09 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structures and immune recognition of Env trimers from two Asia prevalent HIV-1 CRFs. Nat Commun, 14, 2023
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8GPJ
| HIV-1 Env X16 UFO in complex with 8ANC195 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 Fab heavy chain, ... | 著者 | Niu, J, Xu, Y.W, Yang, B. | 登録日 | 2022-08-26 | 公開日 | 2023-08-09 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structures and immune recognition of Env trimers from two Asia prevalent HIV-1 CRFs. Nat Commun, 14, 2023
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8GPG
| HIV-1 Env X18 UFO in complex with F6 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, F6 Fab heavy chain, ... | 著者 | Niu, J, Xu, Y.W, Yang, B. | 登録日 | 2022-08-26 | 公開日 | 2023-08-09 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structures and immune recognition of Env trimers from two Asia prevalent HIV-1 CRFs. Nat Commun, 14, 2023
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8WBO
| Crystal structure of cis-Epoxysuccinate Hydrolases RhCESH[L] mutant D18N complexed with sulfate ions | 分子名称: | Epoxide hydrolase, SULFATE ION | 著者 | Dong, S, Xuan, J.S, Feng, Y.G, Cui, Q. | 登録日 | 2023-09-10 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Deciphering the stereo-specific catalytic mechanisms of cis-epoxysuccinate hydrolases producing L(+)-tartaric acid. J.Biol.Chem., 300, 2024
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8WBT
| Crystal structure of cis-Epoxysuccinate Hydrolases KlCESH[L] mutant D48N complexed with L-TA | 分子名称: | (S)-2-haloacid dehalogenase, CALCIUM ION, GLYCEROL, ... | 著者 | Dong, S, Xuan, J.S, Feng, Y.G, Cui, Q. | 登録日 | 2023-09-10 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Deciphering the stereo-specific catalytic mechanisms of cis-epoxysuccinate hydrolases producing L(+)-tartaric acid. J.Biol.Chem., 300, 2024
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8WBS
| Crystal structure of cis-Epoxysuccinate Hydrolases KlCESH[L]-D48N complexed with sulfate ions | 分子名称: | (S)-2-haloacid dehalogenase, CALCIUM ION, SULFATE ION | 著者 | Dong, S, Xuan, J.S, Feng, Y.G, Cui, Q. | 登録日 | 2023-09-10 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Deciphering the stereo-specific catalytic mechanisms of cis-epoxysuccinate hydrolases producing L(+)-tartaric acid. J.Biol.Chem., 300, 2024
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8WBR
| Crystal structure of cis-Epoxysuccinate Hydrolases KlCESH[L] | 分子名称: | (S)-2-haloacid dehalogenase, CALCIUM ION | 著者 | Dong, S, Xuan, J.S, Feng, Y.G, Cui, Q. | 登録日 | 2023-09-10 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Deciphering the stereo-specific catalytic mechanisms of cis-epoxysuccinate hydrolases producing L(+)-tartaric acid. J.Biol.Chem., 300, 2024
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8WBK
| Crystal structure of cis-Epoxysuccinate Hydrolases RhCESH[L] | 分子名称: | Epoxide hydrolase, SULFATE ION | 著者 | Dong, S, Xuan, J.S, Feng, Y.G, Cui, Q. | 登録日 | 2023-09-10 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Deciphering the stereo-specific catalytic mechanisms of cis-epoxysuccinate hydrolases producing L(+)-tartaric acid. J.Biol.Chem., 300, 2024
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8WBP
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8WBQ
| Crystal structure of cis-Epoxysuccinate Hydrolases RhCESH[L] mutant E212Q complexed with L-TA. | 分子名称: | Epoxide hydrolase, L(+)-TARTARIC ACID | 著者 | Dong, S, Xuan, J.S, Feng, Y.G, Cui, Q. | 登録日 | 2023-09-10 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Deciphering the stereo-specific catalytic mechanisms of cis-epoxysuccinate hydrolases producing L(+)-tartaric acid. J.Biol.Chem., 300, 2024
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8WBN
| Crystal structure of cis-Epoxysuccinate Hydrolases RhCESH[L] mutant D193N | 分子名称: | Epoxide hydrolase, SULFATE ION | 著者 | Dong, S, Xuan, J.S, Feng, Y.G, Cui, Q. | 登録日 | 2023-09-10 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Deciphering the stereo-specific catalytic mechanisms of cis-epoxysuccinate hydrolases producing L(+)-tartaric acid. J.Biol.Chem., 300, 2024
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8WBL
| Crystal structure of cis-Epoxysuccinate Hydrolases RhCESH[L] complexed with sulfate ions | 分子名称: | Epoxide hydrolase, SULFATE ION | 著者 | Dong, S, Xuan, J.S, Feng, Y.G, Cui, Q. | 登録日 | 2023-09-10 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.941 Å) | 主引用文献 | Deciphering the stereo-specific catalytic mechanisms of cis-epoxysuccinate hydrolases producing L(+)-tartaric acid. J.Biol.Chem., 300, 2024
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8WBM
| Crystal structure of cis-Epoxysuccinate Hydrolases RhCESH[L] mutant D193A complexed with sulfate ions | 分子名称: | Epoxide hydrolase, SULFATE ION | 著者 | Dong, S, Xuan, J.S, Feng, Y.G, Cui, Q. | 登録日 | 2023-09-10 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Deciphering the stereo-specific catalytic mechanisms of cis-epoxysuccinate hydrolases producing L(+)-tartaric acid. J.Biol.Chem., 300, 2024
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7CGW
| Complex structure of PD-1 and tislelizumab Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of tislelizumab Fab, Light chain of tislelizumab Fab, ... | 著者 | Hong, Y, Feng, Y.C, Liu, Y. | 登録日 | 2020-07-02 | 公開日 | 2021-04-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Tislelizumab uniquely binds to the CC' loop of PD-1 with slow-dissociated rate and complete PD-L1 blockage. Febs Open Bio, 11, 2021
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8H02
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8K60
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7WWF
| Crystal structure of BioH3 from Mycolicibacterium smegmatis | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Esterase | 著者 | Yang, J, Xu, Y.C, Gan, J.H, Feng, Y.J. | 登録日 | 2022-02-12 | 公開日 | 2022-07-06 | 最終更新日 | 2023-01-18 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Three enigmatic BioH isoenzymes are programmed in the early stage of mycobacterial biotin synthesis, an attractive anti-TB drug target. Plos Pathog., 18, 2022
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8GZ9
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8GZ8
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8WZB
| RS head-neck monomer | 分子名称: | DPY30 domain containing 2, DnaJ homolog subfamily B member 13, Nucleoside diphosphate kinase homolog 5, ... | 著者 | Meng, X, Cong, Y. | 登録日 | 2023-11-01 | 公開日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Multi-scale structures of the mammalian radial spoke and divergence of axonemal complexes in ependymal cilia. Nat Commun, 15, 2024
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8X2U
| Radial spoke head-neck dimer | 分子名称: | DPY30 domain containing 2, DnaJ homolog subfamily B member 13, Nucleoside diphosphate kinase homolog 5, ... | 著者 | Meng, X, Cong, Y. | 登録日 | 2023-11-10 | 公開日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | 主引用文献 | Multi-scale structures of the mammalian radial spoke and divergence of axonemal complexes in ependymal cilia. Nat Commun, 15, 2024
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