5USH
 
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5CEQ
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6BMZ
 | | Influenza A M2 transmembrane domain bound to a spiroadamantane inhibitor | | 分子名称: | (1r,1'S,3'S,5'S,7'S)-spiro[cyclohexane-1,2'-tricyclo[3.3.1.1~3,7~]decan]-4-amine, CHLORIDE ION, Matrix protein 2 | | 著者 | Thomaston, J.L, DeGrado, W.F. | | 登録日 | 2017-11-15 | | 公開日 | 2018-09-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.634 Å) | | 主引用文献 | Inhibitors of the M2 Proton Channel Engage and Disrupt Transmembrane Networks of Hydrogen-Bonded Waters.
J. Am. Chem. Soc., 140, 2018
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5YVT
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6BRS
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2OUH
 | | Crystal structure of the Thrombospondin-1 N-terminal domain in complex with fractionated Heparin DP10 | | 分子名称: | SULFATE ION, Thrombospondin-1 | | 著者 | Tan, K, Joachimiak, A, Wang, J, Lawler, J. | | 登録日 | 2007-02-11 | | 公開日 | 2008-01-08 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Heparin-induced cis- and trans-Dimerization Modes of the Thrombospondin-1 N-terminal Domain.
J.Biol.Chem., 283, 2008
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3L1L
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5WTJ
 | | Crystal structure of an endonuclease | | 分子名称: | CRISPR-associated endoribonuclease C2c2 | | 著者 | Liu, L, Wang, Y. | | 登録日 | 2016-12-13 | | 公開日 | 2017-02-08 | | 最終更新日 | 2017-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.503 Å) | | 主引用文献 | Two Distant Catalytic Sites Are Responsible for C2c2 RNase Activities
Cell, 168, 2017
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5W0K
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6CI4
 | | Crystal structure of the formyltransferase PseJ from Anoxybacillus kamchatkensis soaked with UDP-4-amino-4,6-dideoxy-L-AltNAc | | 分子名称: | (2R,3R,4S,5R,6S)-3-(acetylamino)-5-amino-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, formyltransferase PseJ | | 著者 | Harb, I, Reimer, J.M, Schmeing, T.M. | | 登録日 | 2018-02-23 | | 公開日 | 2018-10-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.824068 Å) | | 主引用文献 | Structural Insight into a Novel Formyltransferase and Evolution to a Nonribosomal Peptide Synthetase Tailoring Domain.
ACS Chem. Biol., 13, 2018
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3FH7
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5ZOV
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7LV8
 | | Structure of the Marseillevirus nucleosome | | 分子名称: | DNA (123-MER), Histone doublet Beta-Alpha (Alpha), Histone doublet Beta-Alpha (Beta), ... | | 著者 | Valencia-Sanchez, M.I, Abini-Agbomson, S, Armache, K.-J. | | 登録日 | 2021-02-24 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-05-26 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | The structure of a virus-encoded nucleosome.
Nat.Struct.Mol.Biol., 28, 2021
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7LV9
 | | Marseillevirus heterotrimeric (hexameric) nucleosome | | 分子名称: | DNA (96-MER), Histone doublet Beta-Alpha (Alpha), Histone doublet Beta-Alpha (Beta), ... | | 著者 | Valencia-Sanchez, M.I, Abini-Agbomson, S, Armache, K.-J. | | 登録日 | 2021-02-24 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-05-26 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | The structure of a virus-encoded nucleosome.
Nat.Struct.Mol.Biol., 28, 2021
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5X26
 | | Crystal structure of EGFR 696-1022 L858R in complex with SKLB(3) | | 分子名称: | CHLORIDE ION, Epidermal growth factor receptor, N2-[4-(4-methylpiperazin-1-yl)phenyl]-N8-phenyl-9-propan-2-yl-purine-2,8-diamine | | 著者 | Yun, C.H. | | 登録日 | 2017-01-31 | | 公開日 | 2018-02-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.951 Å) | | 主引用文献 | Structural insights into drug development strategy targeting EGFR T790M/C797S.
Oncotarget, 9, 2018
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5X2K
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7VLX
 | | Cryo-EM structures of Listeria monocytogenes man-PTS | | 分子名称: | Mannose/fructose/sorbose family PTS transporter subunit IIC, PTS mannose family transporter subunit IID, alpha-D-mannopyranose | | 著者 | Wang, J.W. | | 登録日 | 2021-10-05 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Structural Basis of Pore Formation in the Mannose Phosphotransferase System by Pediocin PA-1.
Appl.Environ.Microbiol., 88, 2022
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7VLY
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2PNT
 | | Crystal structure of the PDZ domain of human GRASP (GRP1) in complex with the C-terminal peptide of the metabotropic glutamate receptor type 1 | | 分子名称: | CHLORIDE ION, General receptor for phosphoinositides 1-associated scaffold protein | | 著者 | Elkins, J, Papagrigoriou, E, Cooper, C, Gileadi, C, Uppenberg, J, Bray, J, von Delft, F, Pike, A.C.W, Ugochukwu, E, Umeano, C, Gileadi, O, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) | | 登録日 | 2007-04-25 | | 公開日 | 2007-05-08 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.148 Å) | | 主引用文献 | Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms
Protein Sci., 19, 2010
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7VI9
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7VII
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5V2N
 | | Crystal Structure of APO Human SETD8 | | 分子名称: | 1,2-ETHANEDIOL, N-lysine methyltransferase KMT5A | | 著者 | Skene, R.J. | | 登録日 | 2017-03-05 | | 公開日 | 2018-03-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The dynamic conformational landscape of the protein methyltransferase SETD8.
Elife, 8, 2019
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7VIA
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5UKQ
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2PA1
 | | Structure of the PDZ domain of human PDLIM2 bound to a C-terminal extension from human beta-tropomyosin | | 分子名称: | CHLORIDE ION, PDZ and LIM domain protein 2 | | 著者 | Uppenberg, J, Shrestha, L, Elkins, J, Burgess-Brown, N, Salah, E, Bunkoczi, G, Papagrigoriou, E, Pike, A.C.W, Turnbull, A.P, Ugochukwu, E, Umeano, C, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) | | 登録日 | 2007-03-27 | | 公開日 | 2007-05-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms
Protein Sci., 19, 2010
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