3IMS
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![BU of 3ims by Molmil](/molmil-images/mine/3ims) | Transthyretin in complex with 2,6-dibromo-4-(2,6-dichlorophenethyl)phenol | 分子名称: | 2,6-dibromo-4-[2-(2,6-dichlorophenyl)ethyl]phenol, Transthyretin | 著者 | Connelly, S, Wilson, I.A. | 登録日 | 2009-08-11 | 公開日 | 2010-01-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity. J.Am.Chem.Soc., 132, 2010
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8EQC
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![BU of 8eqc by Molmil](/molmil-images/mine/8eqc) | |
3GBN
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![BU of 3gbn by Molmil](/molmil-images/mine/3gbn) | Crystal Structure of Fab CR6261 in Complex with the 1918 H1N1 influenza virus hemagglutinin | 分子名称: | 1,2-ETHANEDIOL, 2-ETHOXYETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Ekiert, D.C, Elsliger, M.A, Wilson, I.A. | 登録日 | 2009-02-20 | 公開日 | 2009-03-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Antibody recognition of a highly conserved influenza virus epitope. Science, 324, 2009
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7KKZ
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7KMD
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7KLC
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3GML
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![BU of 3gml by Molmil](/molmil-images/mine/3gml) | Structure of mouse CD1d in complex with C6Ph | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ... | 著者 | Schiefner, A, Wilson, I.A. | 登録日 | 2009-03-14 | 公開日 | 2009-11-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009
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3GMP
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![BU of 3gmp by Molmil](/molmil-images/mine/3gmp) | Structure of mouse CD1d in complex with PBS-25 | 分子名称: | (2S,3S,4R)-N-OCTANOYL-1-[(ALPHA-D-GALACTOPYRANOSYL)OXY]-2-AMINO-OCTADECANE-3,4-DIOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Schiefner, A, Wilson, I.A. | 登録日 | 2009-03-14 | 公開日 | 2009-11-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009
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3GMN
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![BU of 3gmn by Molmil](/molmil-images/mine/3gmn) | Structure of mouse CD1d in complex with C10Ph | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ... | 著者 | Schiefner, A, Wilson, I.A. | 登録日 | 2009-03-14 | 公開日 | 2009-11-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009
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7LMO
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![BU of 7lmo by Molmil](/molmil-images/mine/7lmo) | Structure of full-length human lambda-6A light chain JTO in complex with stabilizer 34 [3-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)-7-(1H-imidazole-5-carbonyl)-1,3,7-triazaspiro[4.4]nonane-2,4-dione] | 分子名称: | (5~{R})-3-[2-[7-(diethylamino)-4-methyl-2-oxidanylidene-chromen-3-yl]ethyl]-7-(1~{H}-imidazol-4-ylcarbonyl)-1,3,7-triazaspiro[4.4]nonane-2,4-dione, JTO light chain, PHOSPHATE ION | 著者 | Yan, N.L, Wilson, I.A, Kelly, J.W. | 登録日 | 2021-02-05 | 公開日 | 2021-05-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Discovery of Potent Coumarin-Based Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains Using Structure-Based Design. J.Med.Chem., 64, 2021
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7LMN
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7LMR
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7LMP
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![BU of 7lmp by Molmil](/molmil-images/mine/7lmp) | Structure of full-length human lambda-6A light chain JTO in complex with stabilizer 36 [3-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)-8-(1H-imidazole-4-carbonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione] | 分子名称: | 3-[2-[7-(diethylamino)-4-methyl-2-oxidanylidene-chromen-3-yl]ethyl]-8-(1~{H}-imidazol-5-ylcarbonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione, JTO light chain, PHOSPHATE ION | 著者 | Yan, N.L, Wilson, I.A, Kelly, J.W. | 登録日 | 2021-02-05 | 公開日 | 2021-05-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Discovery of Potent Coumarin-Based Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains Using Structure-Based Design. J.Med.Chem., 64, 2021
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7LMQ
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3GQ2
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3IMU
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3IMV
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3J5M
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![BU of 3j5m by Molmil](/molmil-images/mine/3j5m) | Cryo-EM structure of the BG505 SOSIP.664 HIV-1 Env trimer with 3 PGV04 Fabs | 分子名称: | BG505 SOSIP gp120, BG505 SOSIP gp41, PGV04 heavy chain, ... | 著者 | Lyumkis, D, Julien, J.-P, Wilson, I.A, Ward, A.B. | 登録日 | 2013-10-26 | 公開日 | 2013-11-13 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | 主引用文献 | Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer. Science, 342, 2013
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3GMO
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![BU of 3gmo by Molmil](/molmil-images/mine/3gmo) | Structure of mouse CD1d in complex with C8PhF | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8-(4-fluorophenyl)-N-{(1S,2S,3R)-1-[(alpha-D-galactopyranosyloxy)methyl]-2,3-dihydroxyheptadecyl}octanamide, ... | 著者 | Schiefner, A, Wilson, I.A. | 登録日 | 2009-03-14 | 公開日 | 2009-11-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009
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4NZT
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4O58
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4NM4
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4NUJ
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2ERJ
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![BU of 2erj by Molmil](/molmil-images/mine/2erj) | Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Debler, E.W, Stauber, D.J, Wilson, I.A. | 登録日 | 2005-10-25 | 公開日 | 2006-02-21 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2GJZ
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