7SIU
 
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2GJF
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6PBS
 | | Structure of ClpC1-NTD in complex with Ecumicin | | 分子名称: | ACETATE ION, ATP-dependent Clp protease ATP-binding subunit ClpC1, ecumicin | | 著者 | Abad-Zapatero, C, Wolf, N.M. | | 登録日 | 2019-06-14 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of the N-terminal domain of ClpC1 in complex with the antituberculosis natural product ecumicin reveals unique binding interactions.
Acta Crystallogr D Struct Biol, 76, 2020
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5XBK
 | | Crystal structure of human Importin4 | | 分子名称: | Importin-4, histone H3 | | 著者 | Song, J.J, Yoon, J. | | 登録日 | 2017-03-20 | | 公開日 | 2018-02-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.223 Å) | | 主引用文献 | Integrative Structural Investigation on the Architecture of Human Importin4_Histone H3/H4_Asf1a Complex and Its Histone H3 Tail Binding
J. Mol. Biol., 430, 2018
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5XAH
 | | Crystal structure of human Importin4 | | 分子名称: | Importin-4 | | 著者 | Song, J.J, Yoon, J. | | 登録日 | 2017-03-13 | | 公開日 | 2018-02-14 | | 最終更新日 | 2018-04-11 | | 実験手法 | X-RAY DIFFRACTION (3.004 Å) | | 主引用文献 | Integrative Structural Investigation on the Architecture of Human Importin4_Histone H3/H4_Asf1a Complex and Its Histone H3 Tail Binding
J. Mol. Biol., 430, 2018
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6CN8
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5ZXB
 | | Crystal structure of ACK1 with compound 10d | | 分子名称: | Activated CDC42 kinase 1, N-{3-[7-{[6-(4-acetylpiperazin-1-yl)pyridin-3-yl]amino}-1-methyl-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamide | | 著者 | Hong, E.M, Kim, H.L, Sim, T.B. | | 登録日 | 2018-05-18 | | 公開日 | 2018-09-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | | 主引用文献 | First SAR Study for Overriding NRAS Mutant Driven Acute Myeloid Leukemia.
J. Med. Chem., 61, 2018
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6PBA
 | | Structure of ClpC1-NTD | | 分子名称: | ATP-dependent Clp protease ATP-binding subunit ClpC1 | | 著者 | Abad-Zapatero, C, Wolf, N.M. | | 登録日 | 2019-06-13 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Structure of the N-terminal domain of ClpC1 in complex with the antituberculosis natural product ecumicin reveals unique binding interactions.
Acta Crystallogr D Struct Biol, 76, 2020
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6PBQ
 | | Structure of ClpC1-NTD | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ATP-dependent Clp protease ATP-binding subunit ClpC1, PHOSPHATE ION | | 著者 | Abad-Zapatero, C, Wolf, N.M. | | 登録日 | 2019-06-14 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of the N-terminal domain of ClpC1 in complex with the antituberculosis natural product ecumicin reveals unique binding interactions.
Acta Crystallogr D Struct Biol, 76, 2020
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6CHV
 | | Proteus vulgaris HigA antitoxin bound to DNA | | 分子名称: | Antitoxin HigA, MAGNESIUM ION, pHigCryst3, ... | | 著者 | Schureck, M.A, Hoffer, E.D, Onuoha, N, Dunham, C.M. | | 登録日 | 2018-02-23 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis of transcriptional regulation by the HigA antitoxin.
Mol.Microbiol., 111, 2019
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6CWJ
 | | Crystal structures of cyanuric acid hydrolase from Moorella thermoacetica complexed with 1,3-Acetone Dicarboxylic Acid | | 分子名称: | 1,3-PROPANDIOL, 3-oxopentanedioic acid, ACETATE ION, ... | | 著者 | Shi, K, Aihara, H. | | 登録日 | 2018-03-30 | | 公開日 | 2019-06-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.253 Å) | | 主引用文献 | Crystal structures of Moorella thermoacetica cyanuric acid hydrolase reveal conformational flexibility and asymmetry important for catalysis.
Plos One, 14, 2019
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6DHJ
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6AGO
 | | Crystal structure of MRG15-ASH1L Histone methyltransferase complex | | 分子名称: | Histone-lysine N-methyltransferase ASH1L, Mortality factor 4 like 1, S-ADENOSYLMETHIONINE, ... | | 著者 | Lee, Y, Song, J. | | 登録日 | 2018-08-13 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.103 Å) | | 主引用文献 | Structural Basis of MRG15-Mediated Activation of the ASH1L Histone Methyltransferase by Releasing an Autoinhibitory Loop.
Structure, 27, 2019
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6PGK
 | | Membrane Protein Megahertz Crystallography at the European XFEL, Photosystem I XFEL at 2.9 A | | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | | 著者 | Fromme, R, Gisriel, C, Fromme, P. | | 登録日 | 2019-06-24 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Membrane protein megahertz crystallography at the European XFEL.
Nat Commun, 10, 2019
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1COJ
 | | FE-SOD FROM AQUIFEX PYROPHILUS, A HYPERTHERMOPHILIC BACTERIUM | | 分子名称: | FE (III) ION, PROTEIN (SUPEROXIDE DISMUTASE) | | 著者 | Lim, J.H, Yu, Y.G, Kim, S.-H, Cho, S.-J, Ahn, B.Y, Han, Y.S, Cho, Y. | | 登録日 | 1999-05-28 | | 公開日 | 1999-06-14 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The crystal structure of an Fe-superoxide dismutase from the hyperthermophile Aquifex pyrophilus at 1.9 A resolution: structural basis for thermostability.
J.Mol.Biol., 270, 1997
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6CHZ
 | | Estrogen Receptor Alpha Y537S bound to antagonist H3B-9224. | | 分子名称: | 1,2-ETHANEDIOL, 4-[(2-{4-[(1E)-1-(1H-indazol-5-yl)-2-phenylbut-1-en-1-yl]phenoxy}ethyl)amino]-N,N-dimethylbutanamide, Estrogen receptor | | 著者 | Larsen, N.A. | | 登録日 | 2018-02-23 | | 公開日 | 2018-03-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ER alphaWTand ER alphaMUTBreast Cancer.
Cancer Discov, 8, 2018
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6BUN
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6BUP
 | | Crystal structures of cyanuric acid hydrolase from Moorella thermoacetica complexed with cyanuric acid | | 分子名称: | 1,3,5-triazine-2,4,6-triol, 1,3-PROPANDIOL, CALCIUM ION, ... | | 著者 | Shi, K, Aihara, H. | | 登録日 | 2017-12-11 | | 公開日 | 2019-06-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Crystal structures of Moorella thermoacetica cyanuric acid hydrolase reveal conformational flexibility and asymmetry important for catalysis.
Plos One, 14, 2019
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6BUR
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6BUO
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6BUQ
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1I69
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1I6A
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5K5B
 | | Wild-type PAS-GAF fragment from Deinococcus radiodurans BphP | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, ACETATE ION, ... | | 著者 | Takala, H, Edlund, P, Claesson, E, Ihalainen, J.A, Westenhoff, S. | | 登録日 | 2016-05-23 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | The room temperature crystal structure of a bacterial phytochrome determined by serial femtosecond crystallography.
Sci Rep, 6, 2016
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5CZV
 | | Crystal structure of Notch3 NRR in complex with 20350 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fab 20350 heavy chain, ... | | 著者 | Hu, T, Fryer, C, Chopra, R, Clark, K. | | 登録日 | 2015-08-01 | | 公開日 | 2016-06-01 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | | 主引用文献 | Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies.
Oncogene, 35, 2016
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