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2VJU
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BU of 2vju by Molmil
Crystal structure of the IS608 transposase in complex with the complete Right end 35-mer DNA and manganese
分子名称: MANGANESE (II) ION, RIGHT END 35-MER, TRANSPOSASE ORFA
著者Barabas, O, Ronning, D.R, Guynet, C, Hickman, A.B, Ton-Hoang, B, Chandler, M, Dyda, F.
登録日2007-12-13
公開日2008-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mechanism of is200/is605 Family DNA Transposases: Activation and Transposon-Directed Target Site Selection.
Cell(Cambridge,Mass.), 132, 2008
1SHP
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BU of 1shp by Molmil
THE NMR SOLUTION STRUCTURE OF A KUNITZ-TYPE PROTEINASE INHIBITOR FROM THE SEA ANEMONE STICHODACTYLA HELIANTHUS
分子名称: TRYPSIN INHIBITOR
著者Antuch, W, Berndt, K, Chavez, M, Delfin, J, Wuthrich, K.
登録日1992-11-17
公開日1994-01-31
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献The NMR solution structure of a Kunitz-type proteinase inhibitor from the sea anemone Stichodactyla helianthus.
Eur.J.Biochem., 212, 1993
1SPY
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BU of 1spy by Molmil
REGULATORY DOMAIN OF HUMAN CARDIAC TROPONIN C IN THE CALCIUM-FREE STATE, NMR, 40 STRUCTURES
分子名称: TROPONIN C
著者Spyracopoulos, L, Li, M.X, Sia, S.K, Gagne, S.M, Chandra, M, Solaro, R.J, Sykes, B.D.
登録日1997-07-14
公開日1998-09-16
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Calcium-induced structural transition in the regulatory domain of human cardiac troponin C.
Biochemistry, 36, 1997
2LDD
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BU of 2ldd by Molmil
Solution structure of the estrogen receptor-binding stapled peptide SP6 (Ac-EKHKILXRLLXDS-NH2)
分子名称: Estrogen receptor-binding stapled peptide SP6
著者Phillips, C, Bazin, R, Bent, A, Davies, N, Moore, R, Pannifer, A, Pickford, A, Prior, S, Read, C, Roberts, L, Schade, M, Scott, A, Brown, D, Xu, B, Irving, S.
登録日2011-05-21
公開日2011-07-06
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Design and structure of stapled peptides binding to estrogen receptors.
J.Am.Chem.Soc., 133, 2011
2LDA
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BU of 2lda by Molmil
Solution structure of the estrogen receptor-binding stapled peptide SP2 (Ac-HKXLHQXLQDS-NH2)
分子名称: Estrogen receptor-binding stapled peptide SP2
著者Phillips, C, Bazin, R, Bent, A, Davies, N, Moore, R, Pannifer, A, Pickford, A, Prior, S, Read, C, Roberts, L, Schade, M, Scott, A, Brown, D, Xu, B, Irving, S.
登録日2011-05-20
公開日2011-07-06
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Design and structure of stapled peptides binding to estrogen receptors.
J.Am.Chem.Soc., 133, 2011
2K28
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BU of 2k28 by Molmil
Solution NMR structure of the chromo domain of the chromobox protein homolog 4
分子名称: E3 SUMO-protein ligase CBX4
著者Kaustov, L, Lemak, A, Quyang, H, Fares, C, Gutmanas, A, Ravichandran, M, Loppnau, P, Bountra, C, Weigelt, J, Edwards, A.M, Min, J, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
登録日2008-03-27
公開日2008-04-08
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution NMR structure of the chromo domain of the chromobox protein homolog 4.
To be Published
2K1B
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BU of 2k1b by Molmil
Solution NMR structure of the chromo domain of the chromobox protein homolog 7
分子名称: Chromobox protein homolog 7
著者Kaustov, L, Lemak, A, Quyang, H, Gutmanas, A, Fares, C, Bountra, C, Weigelt, J, Loppnau, P, Ravichandran, M, Edwards, A.M, Min, J, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
登録日2008-02-25
公開日2008-03-11
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution NMR structure of the chromobox protein homolog 7.
To be Published
2LDC
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BU of 2ldc by Molmil
Solution structure of the estrogen receptor-binding stapled peptide SP1 (Ac-HXILHXLLQDS-NH2)
分子名称: Estrogen receptor-binding stapled peptide SP1
著者Phillips, C, Bazin, R, Bent, A, Davies, N, Moore, R, Pannifer, A, Pickford, A, Prior, S, Read, C, Roberts, L, Schade, M, Scott, A, Brown, D, Xu, B, Irving, S.
登録日2011-05-20
公開日2011-07-06
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Design and structure of stapled peptides binding to estrogen receptors.
J.Am.Chem.Soc., 133, 2011
6XOG
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BU of 6xog by Molmil
Structure of SUMO1-ML786519 adduct bound to SAE
分子名称: SULFATE ION, SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ...
著者Sintchak, M, Lane, W, Bump, N.
登録日2020-07-07
公開日2021-03-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer.
J.Med.Chem., 64, 2021
6XOH
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BU of 6xoh by Molmil
Structure of SUMO1-ML00789344 adduct bound to SAE
分子名称: SULFATE ION, SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ...
著者Sintchak, M, Lane, W, Bump, N.
登録日2020-07-07
公開日2021-03-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.226 Å)
主引用文献Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer.
J.Med.Chem., 64, 2021
6XOI
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BU of 6xoi by Molmil
Structure of SUMO1-ML00752641 adduct bound to SAE
分子名称: SULFATE ION, SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ...
著者Sintchak, M, Lane, W, Bump, N.
登録日2020-07-07
公開日2021-03-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer.
J.Med.Chem., 64, 2021
8B3E
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BU of 8b3e by Molmil
Variant Surface Glycoprotein VSG397
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Variant surface glycoprotein 397
著者Zeelen, J.P, Stebbins, C.E, Dakovic, S, Foti, K.
登録日2022-09-16
公開日2023-01-25
最終更新日2023-04-19
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome.
Plos Negl Trop Dis, 17, 2023
6T3O
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BU of 6t3o by Molmil
Crystal structure of the human myomesin domain 10
分子名称: AZIDE ION, Myomesin-1
著者Duskova, J, Petrokova, H, Maly, P.
登録日2019-10-11
公開日2021-03-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Myomedin scaffold variants targeted to 10E8 HIV-1 broadly neutralizing antibody mimic gp41 epitope and elicit HIV-1 virus-neutralizing sera in mice.
Virulence, 12, 2021
7NE3
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BU of 7ne3 by Molmil
Human TET2 in complex with favourable DNA substrate.
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*AP*CP*AP*GP*GP*(5CM)P*GP*CP*CP*TP*G)-3'), ...
著者Rafalski, D, Bochtler, M.
登録日2021-02-03
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function.
Sci Adv, 8, 2022
7NE6
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BU of 7ne6 by Molmil
Human TET2 in complex with unfavourable DNA substrate.
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*AP*CP*AP*GP*GP*(5CM)P*GP*CP*CP*TP*G)-3'), ...
著者Rafalski, D, Bochtler, M.
登録日2021-02-03
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function.
Sci Adv, 8, 2022
5LSF
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BU of 5lsf by Molmil
Sacbrood honeybee virus
分子名称: CALCIUM ION, VP1, VP2, ...
著者Plevka, P, Veselikova, M.
登録日2016-08-26
公開日2018-08-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Virion structure and genome delivery mechanism of sacbrood honeybee virus.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7MZV
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BU of 7mzv by Molmil
Structure of yeast pseudouridine synthase 7 (PUS7)
分子名称: Multisubstrate pseudouridine synthase 7, SULFATE ION
著者Purchal, M, Koutmos, M.
登録日2021-05-24
公開日2022-02-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Pseudouridine synthase 7 is an opportunistic enzyme that binds and modifies substrates with diverse sequences and structures.
Proc.Natl.Acad.Sci.USA, 119, 2022
5WOE
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BU of 5woe by Molmil
Solution structure of the sorting nexin 25 phox-homology domain
分子名称: Sorting nexin-25
著者Chin, Y.K.Y, Mas, C, Mobli, M, Collins, B.M.
登録日2017-08-01
公開日2018-08-08
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Nat Commun, 10, 2019
5UKE
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BU of 5uke by Molmil
NMR structure of monomeric human IRAK-M Death Domain R56D, Y61E mutant
分子名称: Interleukin-1 receptor-associated kinase 3
著者Kwon, J, Nicholson, L.K.
登録日2017-01-20
公開日2018-01-24
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The IL-33-PIN1-IRAK-M axis is critical for type 2 immunity in IL-33-induced allergic airway inflammation.
Nat Commun, 9, 2018
5G1X
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BU of 5g1x by Molmil
Crystal structure of Aurora-A kinase in complex with N-Myc
分子名称: ADENOSINE-5'-DIPHOSPHATE, AURORA KINASE A, MAGNESIUM ION, ...
著者Richards, M.W, Burgess, S.G, Bayliss, R.
登録日2016-03-31
公開日2016-11-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Structural Basis of N-Myc Binding by Aurora-A and its Destabilization by Kinase Inhibitors
Proc.Natl.Acad.Sci.USA, 113, 2016
5C7G
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BU of 5c7g by Molmil
Crystal Structure of the b1 Domain of Human Neuropilin-1 in complex with a bicine molecule
分子名称: BICINE, Neuropilin-1, SODIUM ION
著者Didierjean, C, Jelsch, C.
登録日2015-06-24
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Design, synthesis and biological evaluation of new peptidomimetic compounds targeting NRP-1 receptor TO BE PUBLISHED
To Be Published
1EGZ
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BU of 1egz by Molmil
CELLULASE CEL5 FROM ERWINIA CHRYSANTHEMI, A FAMILY GH 5-2 ENZYME
分子名称: CALCIUM ION, ENDOGLUCANASE Z
著者Czjzek, M, El Hassouni, M, Py, B, Barras, F.
登録日1999-03-18
公開日1999-03-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Type II protein secretion in gram-negative pathogenic bacteria: the study of the structure/secretion relationships of the cellulase Cel5 (formerly EGZ) from Erwinia chrysanthemi
J.Mol.Biol., 310, 2001
4K3J
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BU of 4k3j by Molmil
Crystal structure of Onartuzumab Fab in complex with MET and HGF-beta
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hepatocyte growth factor, Hepatocyte growth factor beta chain, ...
著者Ma, X, Starovasnik, M.A.
登録日2013-04-10
公開日2013-08-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent.
Proc.Natl.Acad.Sci.USA, 110, 2013
1SHO
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BU of 1sho by Molmil
CRYSTAL STRUCTURE OF VANCOMYCIN AT ATOMIC RESOLUTION
分子名称: ACETATE ION, CHLORIDE ION, VANCOMYCIN, ...
著者Sheldrick, G.M.
登録日1997-07-23
公開日1997-12-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.09 Å)
主引用文献Crystal Structure of Vancomycin.
Structure, 4, 1996
5UTF
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BU of 5utf by Molmil
Crystal Structure of a Stabilized DS-SOSIP.6mut BG505 gp140 HIV-1 Env Trimer, Containing Mutations I201C-P433C (DS), L154M, Y177W, N300M, N302M, T320L, I420M in Complex with Human Antibodies PGT122 and 35O22 at 4.3 A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35022 Heavy chain, ...
著者Pancera, M, Chuang, G.-Y, Xu, K, Kwong, P.D.
登録日2017-02-14
公開日2017-03-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.503 Å)
主引用文献Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity.
J. Virol., 91, 2017

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