5UKE

NMR structure of monomeric human IRAK-M Death Domain R56D, Y61E mutant

Summary for 5UKE

• Entry DOI: 10.2210/pdb5uke/pdb
• NMR Information: BMRB: 30237
• Descriptor: Interleukin-1 receptor-associated kinase 3 (1 entity in total)
• Functional Keywords: irak-m, death domain, innate immunity, asthma, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 13467.16

Authors

Kwon, J.,Nicholson, L.K. (deposition date: 2017-01-20, release date: 2018-01-24, Last modification date: 2019-12-04)

• Primary citation: Nechama, M.,Kwon, J.,Wei, S.,Kyi, A.T.,Welner, R.S.,Ben-Dov, I.Z.,Arredouani, M.S.,Asara, J.M.,Chen, C.H.,Tsai, C.Y.,Nelson, K.F.,Kobayashi, K.S.,Israel, E.,Zhou, X.Z.,Nicholson, L.K.,Lu, K.P.; The IL-33-PIN1-IRAK-M axis is critical for type 2 immunity in IL-33-induced allergic airway inflammation.; Nat Commun, 9:1603-1603, 2018; PubMed: 29686383; DOI: 10.1038/s41467-018-03886-6

Experimental method

SOLUTION NMR