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7JZ1
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BU of 7jz1 by Molmil
Crystal structure of broadly Plasmodium RIFIN reactive LAIR1-inserted antibody MGC34
分子名称: MGC34 heavy chain, MGC34 light chain
著者Xu, K, Kwong, P.D.
登録日2020-09-01
公開日2021-05-26
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.37 Å)
主引用文献Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
7JZI
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BU of 7jzi by Molmil
Crystal structure of LAIR1 ectodomain (from MGD21) in complex with Plasmodium RIFIN (PF3D7_1040300) V2 domain
分子名称: LAIR1 ectodomain from antibody MGD21, PLATINUM (II) ION, Rifin
著者Xu, K, Kwong, P.D.
登録日2020-09-02
公開日2021-05-26
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.707 Å)
主引用文献Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
7QWL
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BU of 7qwl by Molmil
TMEM106B filaments with Fold IIb from Multiple system atrophy (case 19)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-25
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QVC
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BU of 7qvc by Molmil
TMEM106B filaments with Fold I from Alzheimer's disease (case 1)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-21
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
6W03
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BU of 6w03 by Molmil
Crystal Structure of HIV-1 BG505 DS-SOSIP.3mut Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.3 Angstrom
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain, ...
著者Lai, Y.-T, Kwong, P.D.
登録日2020-02-28
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses.
J.Virol., 94, 2020
7QVF
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BU of 7qvf by Molmil
TMEM106B filaments with Fold I-d from Multiple system atrophy (case 18)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-21
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWG
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BU of 7qwg by Molmil
TMEM106B filaments with Fold IIa from Multiple system atrophy (case 19)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-25
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWM
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TMEM106B filaments with Fold III from Multiple system atrophy (case 17)
分子名称: Transmembrane protein 106B
著者Lovestam, S, Schweighauser, M, Scheres, S.H.W.
登録日2022-01-25
公開日2022-03-09
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
6VZI
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BU of 6vzi by Molmil
Crystal Structure of HIV-1 CAP256 RnS-3mut-2G-SOSIP.664 Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain, ...
著者Lai, Y.-T, Kwong, P.D.
登録日2020-02-28
公開日2020-04-15
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.716 Å)
主引用文献Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses.
J.Virol., 94, 2020
6WIX
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BU of 6wix by Molmil
Crystal Structure of HIV-1 MI369 RnS-DS.SOSIP Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Lai, Y.-T, Olia, A, Kwong, P.D.
登録日2020-04-10
公開日2020-11-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Automated Design by Structure-Based Stabilization and Consensus Repair to Achieve Prefusion-Closed Envelope Trimers in a Wide Variety of HIV Strains.
Cell Rep, 33, 2020
7LKG
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BU of 7lkg by Molmil
Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.151
分子名称: Circumsporozoite protein, m43.151 Fab Heavy Chain, m43.151 Fab Light chain
著者Xu, K, Kwong, P.D.
登録日2021-02-02
公開日2021-12-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
7LKB
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BU of 7lkb by Molmil
Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m42.127
分子名称: Circumsporozoite protein, SULFATE ION, m42.127 Fab heavy Chain, ...
著者Xu, K, Kwong, P.D.
登録日2021-02-02
公開日2021-12-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
7LPN
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BU of 7lpn by Molmil
Cryo-EM structure of llama J3 VHH antibody in complex with HIV-1 Env BG505 DS-SOSIP.664
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Gorman, J, Kwong, P.D.
登録日2021-02-12
公開日2022-02-23
最終更新日2023-03-29
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site.
Structure, 30, 2022
8DER
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BU of 8der by Molmil
Cryo-EM local refinement of antibody SKV16 in complex with VEEV alphavirus spike glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SKV16 Fab Heavy Chain, ...
著者Casner, R.G, Verardi, R, Roederer, M, Shapiro, L.
登録日2022-06-21
公開日2023-06-28
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
8DEQ
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BU of 8deq by Molmil
Cryo-EM local refinement of antibody SKV09 in complex with VEEV alphavirus spike glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SKV09 Fab Heavy Chain, SKV09 Fab Light Chain, ...
著者Casner, R.G, Verardi, R, Roederer, M, Shapiro, L.
登録日2022-06-21
公開日2023-06-28
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
6U63
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BU of 6u63 by Molmil
Mcl-1 bound to compound 17
分子名称: 2-{[(naphthalen-2-yl)sulfonyl]amino}-5-[(2-phenylethyl)sulfanyl]benzoic acid, Induced myeloid leukemia cell differentiation protein Mcl-1
著者Stuckey, J.A.
登録日2019-08-29
公開日2020-03-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Discovery and Characterization of 2,5-Substituted Benzoic Acid Dual Inhibitors of the Anti-apoptotic Mcl-1 and Bfl-1 Proteins.
J.Med.Chem., 63, 2020
6U65
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BU of 6u65 by Molmil
Mcl-1 bound to compound 19
分子名称: 1,2-ETHANEDIOL, 2-[({4-[(4-fluorophenyl)methyl]piperazin-1-yl}sulfonyl)amino]-5-[(2-phenylethyl)sulfanyl]benzoic acid, ACETATE ION, ...
著者Stuckey, J.A.
登録日2019-08-29
公開日2020-03-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Discovery and Characterization of 2,5-Substituted Benzoic Acid Dual Inhibitors of the Anti-apoptotic Mcl-1 and Bfl-1 Proteins.
J.Med.Chem., 63, 2020
6U64
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BU of 6u64 by Molmil
Mcl-1 bound to compound 17
分子名称: 5-[(2-phenylethyl)sulfanyl]-2-{[(4-phenylpiperazin-1-yl)sulfonyl]amino}benzoic acid, Induced myeloid leukemia cell differentiation protein Mcl-1
著者Stuckey, J.A.
登録日2019-08-29
公開日2020-03-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Discovery and Characterization of 2,5-Substituted Benzoic Acid Dual Inhibitors of the Anti-apoptotic Mcl-1 and Bfl-1 Proteins.
J.Med.Chem., 63, 2020
6U67
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BU of 6u67 by Molmil
Mcl-1 bound to compound 24
分子名称: 2-({[4-(4-tert-butylphenyl)piperazin-1-yl]sulfonyl}amino)-5-{[3-oxo-3-(phenylamino)propyl]sulfanyl}benzoic acid, BIPHENYL, Induced myeloid leukemia cell differentiation protein Mcl-1
著者Stuckey, J.A.
登録日2019-08-29
公開日2020-03-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Discovery and Characterization of 2,5-Substituted Benzoic Acid Dual Inhibitors of the Anti-apoptotic Mcl-1 and Bfl-1 Proteins.
J.Med.Chem., 63, 2020
8K11
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BU of 8k11 by Molmil
SID1 transmembrane family member 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 2
著者Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X.
登録日2023-07-10
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity.
Cell Res., 34, 2024
8K12
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BU of 8k12 by Molmil
SID1 transmembrane family member 2
分子名称: SID1 transmembrane family member 2
著者Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X.
登録日2023-07-10
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity.
Cell Res., 34, 2024
8K1B
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BU of 8k1b by Molmil
SID1 transmembrane family member 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 1
著者Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X.
登録日2023-07-10
公開日2024-07-10
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity.
Cell Res., 34, 2024
8K10
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BU of 8k10 by Molmil
SID1 transmembrane family member 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 2
著者Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X.
登録日2023-07-10
公開日2024-07-10
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity.
Cell Res., 34, 2024
8K13
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BU of 8k13 by Molmil
SID1 transmembrane family member 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 1
著者Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X.
登録日2023-07-10
公開日2024-07-10
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity.
Cell Res., 34, 2024
8K1D
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BU of 8k1d by Molmil
SID1 transmembrane family member 1
分子名称: SID1 transmembrane family member 1
著者Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X.
登録日2023-07-10
公開日2024-07-10
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity.
Cell Res., 34, 2024

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