5HAD
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4FI9
| Structure of human SUN-KASH complex | 分子名称: | Nesprin-2, SUN domain-containing protein 2 | 著者 | Wang, W.J, Shi, Z.B. | 登録日 | 2012-06-08 | 公開日 | 2012-07-18 | 最終更新日 | 2013-03-06 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structural insights into SUN-KASH complexes across the nuclear envelope. Cell Res., 22, 2012
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8HF2
| Cryo-EM structure of WeiTsing | 分子名称: | PRA1 family protein | 著者 | Qin, L, Tang, L.H, Chen, Y.H. | 登録日 | 2022-11-09 | 公開日 | 2023-06-21 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (4.14 Å) | 主引用文献 | WeiTsing, a pericycle-expressed ion channel, safeguards the stele to confer clubroot resistance. Cell, 186, 2023
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7ZW4
| Crystal structure of Talin R7R8 domains with Caskin-2 LD-peptide | 分子名称: | Caskin-2, Talin-1 | 著者 | Celie, P.H.N, Joosten, R.P, Sonnenberg, A, Perrakis, A. | 登録日 | 2022-05-18 | 公開日 | 2023-05-31 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Caskin2 is a novel talin- and Abi1-binding protein that promotes cell motility. J.Cell.Sci., 137, 2024
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8XZG
| Cryo-EM structure of the [Pyr1]-apelin-13-bound human APLNR-Gi complex | 分子名称: | Apelin receptor, Apelin-13, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Wang, W, Ji, S, Zhang, Y. | 登録日 | 2024-01-21 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure-based design of non-hypertrophic apelin receptor modulator. Cell, 187, 2024
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8XZF
| Cryo-EM structure of the WN561-bound human APLNR-Gi complex | 分子名称: | Apelin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Wang, W, Ji, S, Zhang, Y. | 登録日 | 2024-01-21 | 公開日 | 2024-03-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure-based design of non-hypertrophic apelin receptor modulator. Cell, 187, 2024
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8XZJ
| Cryo-EM structure of the WN353-bound human APLNR-Gi complex | 分子名称: | Apelin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Wang, W, Ji, S, Zhang, Y. | 登録日 | 2024-01-21 | 公開日 | 2024-03-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure-based design of non-hypertrophic apelin receptor modulator. Cell, 187, 2024
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8XZI
| Cryo-EM structure of the CMF-019-bound human APLNR-Gi complex | 分子名称: | (3~{S})-5-methyl-3-[[1-pentan-3-yl-2-(thiophen-2-ylmethyl)benzimidazol-5-yl]carbonylamino]hexanoic acid, Apelin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Wang, W, Ji, S, Zhang, Y. | 登録日 | 2024-01-21 | 公開日 | 2024-03-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structure-based design of non-hypertrophic apelin receptor modulator. Cell, 187, 2024
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8XZH
| Cryo-EM structure of the MM07-bound human APLNR-Gi complex | 分子名称: | Apelin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Wang, W, Ji, S, Zhang, Y. | 登録日 | 2024-01-21 | 公開日 | 2024-03-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structure-based design of non-hypertrophic apelin receptor modulator. Cell, 187, 2024
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3RER
| Crystal structure of E. coli Hfq in complex with AU6A RNA and ADP | 分子名称: | 5'-R(*AP*UP*UP*UP*UP*UP*UP*A)-3', ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Wang, W.W, Wu, J.H, Shi, Y.Y. | 登録日 | 2011-04-05 | 公開日 | 2011-10-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Cooperation of Escherichia coli Hfq hexamers in DsrA binding. Genes Dev., 25, 2011
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3RES
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2REW
| Crystal Structure of PPARalpha ligand binding domain with BMS-631707 | 分子名称: | (2S,3S)-1-(4-METHOXYPHENYL)-3-(3-(2-(5-METHYL-2-PHENYLOXAZOL-4-YL)ETHOXY)BENZYL)-4-OXOAZETIDINE-2-CARBOXYLIC ACID, N,N-BIS(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE, Peroxisome proliferator-activated receptor alpha | 著者 | Muckelbauer, J. | 登録日 | 2007-09-27 | 公開日 | 2007-11-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Discovery of Azetidinone Acids as Conformationally-Constrained Dual (alpha/gamma) PPAR Activators To be Published
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3Q0T
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4HT9
| Crystal structure of E coli Hfq bound to two RNAs | 分子名称: | Protein hfq, RNA (5'-R(*AP*AP*AP*AP*AP*AP*A)-3'), RNA (5'-R(*AP*UP*UP*UP*UP*UP*UP*A)-3') | 著者 | Wang, W.W, Wang, L.J. | 登録日 | 2012-11-01 | 公開日 | 2013-04-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Hfq-bridged ternary complex is important for translation activation of rpoS by DsrA. Nucleic Acids Res., 41, 2013
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5VA2
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5VA3
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5ZND
| 8-mer nanotube derived from 24-mer rHuHF nanocage | 分子名称: | Ferritin heavy chain | 著者 | Wang, W.M, Wang, L.L, Zang, J.C, Chen, H, Zhao, G.H, Wang, H.F. | 登録日 | 2018-04-09 | 公開日 | 2018-11-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Selective Elimination of the Key Subunit Interfaces Facilitates Conversion of Native 24-mer Protein Nanocage into 8-mer Nanorings. J. Am. Chem. Soc., 140, 2018
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5VA1
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3CTB
| Tethered PXR-LBD/SRC-1p apoprotein | 分子名称: | Pregnane X receptor, Linker, Steroid receptor coactivator 1 | 著者 | Lesburg, C.A. | 登録日 | 2008-04-11 | 公開日 | 2008-12-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Construction and characterization of a fully active PXR/SRC-1 tethered protein with increased stability Protein Eng.Des.Sel., 21, 2008
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4HT8
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7FAS
| VAR2CSA 3D7 ectodomain core region | 分子名称: | Erythrocyte membrane protein 1, PfEMP1 | 著者 | Wang, L, Zhaoning, W. | 登録日 | 2021-07-07 | 公開日 | 2021-11-17 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum. Cell Discov, 7, 2021
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3SX4
| Crystal structure of human dpp-iv in complex with sa-(+)-3-(aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methoxyphenyl)- 2-methyl-5h-pyrrolo[3,4-b]pyridin-7(6h)-one | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methoxyphenyl)-2-methyl-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one, ... | 著者 | Klei, H.E. | 登録日 | 2011-07-14 | 公開日 | 2011-10-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | 7-Oxopyrrolopyridine-derived DPP4 inhibitors-mitigation of CYP and hERG liabilities via introduction of polar functionalities in the active site. Bioorg.Med.Chem.Lett., 21, 2011
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3SWW
| Crystal structure of human dpp-iv in complex with sa-(+)-3-(aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methoxyphenyl)- 2-methyl-5h-pyrrolo[3,4-b]pyridin-7(6h)-one | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methoxyethyl)-2-methyl-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one, ... | 著者 | Klei, H.E. | 登録日 | 2011-07-14 | 公開日 | 2011-10-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | 7-Oxopyrrolopyridine-derived DPP4 inhibitors-mitigation of CYP and hERG liabilities via introduction of polar functionalities in the active site. Bioorg.Med.Chem.Lett., 21, 2011
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4RUU
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6LGN
| The atomic structure of varicella zoster virus C-capsid | 分子名称: | Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ... | 著者 | Li, S, Zheng, Q. | 登録日 | 2019-12-05 | 公開日 | 2020-07-29 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | 主引用文献 | Near-atomic cryo-electron microscopy structures of varicella-zoster virus capsids. Nat Microbiol, 5, 2020
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