3CTB

Tethered PXR-LBD/SRC-1p apoprotein

Summary for 3CTB

• Entry DOI: 10.2210/pdb3ctb/pdb
• Related: 1ILG 1ILH 1NRL 3CTC
• Descriptor: Pregnane X receptor, Linker, Steroid receptor coactivator 1 (2 entities in total)
• Functional Keywords: pxr, src-1, tethered, engineered, drug-drug interactions, dna-binding, metal-binding, nucleus, receptor, transcription regulation, zinc-finger, transcription, transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : Q15788
• Total number of polymer chains: 2
• Total formula weight: 78368.07

Authors

Lesburg, C.A. (deposition date: 2008-04-11, release date: 2008-12-02, Last modification date: 2023-08-30)

• Primary citation: Wang, W.,Prosise, W.W.,Chen, J.,Taremi, S.S.,Le, H.V.,Madison, V.,Cui, X.,Thomas, A.,Cheng, K.C.,Lesburg, C.A.; Construction and characterization of a fully active PXR/SRC-1 tethered protein with increased stability; Protein Eng.Des.Sel., 21:425-433, 2008; PubMed: 18456871; DOI: 10.1093/protein/gzn017

Experimental method

X-RAY DIFFRACTION (2 Å)