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6ZLY
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BU of 6zly by Molmil
Crystal structure of the complex between PPARgamma LBD and the ligand NV1362 (7a)
分子名称: (2~{S})-2-[(4-hexoxyphenyl)carbonylamino]-3-methyl-butanoic acid, Peroxisome proliferator-activated receptor gamma
著者Pochetti, G, Montanari, R, Capelli, D.
登録日2020-07-01
公開日2020-11-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor gamma Binding Properties and Biological Activities.
J.Med.Chem., 63, 2020
1F88
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BU of 1f88 by Molmil
CRYSTAL STRUCTURE OF BOVINE RHODOPSIN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MERCURY (II) ION, RETINAL, ...
著者Okada, T, Palczewski, K, Stenkamp, R.E, Miyano, M.
登録日2000-06-29
公開日2000-08-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of rhodopsin: A G protein-coupled receptor.
Science, 289, 2000
6G52
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BU of 6g52 by Molmil
CRYSTAL STRUCTURE OF THE CNMP BINDING DOMAIN OF THE MAGNESIUM TRANSPORTER CNNM4
分子名称: Metal transporter CNNM4
著者Gimenez, P, Oyenarte, I, Hardy, S, Zubillaga, M, Merino, N, Blanco, F.J, Siliqi, D, Tremblay, M, Muller, D, Martinez-Cruz, L.A.
登録日2018-03-28
公開日2019-04-10
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (3.691 Å)
主引用文献Structural Insights into the Intracellular Region of the Human Magnesium Transport Mediator CNNM4.
Int J Mol Sci, 20, 2019
1HC1
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BU of 1hc1 by Molmil
CRYSTAL STRUCTURE OF HEXAMERIC HAEMOCYANIN FROM PANULIRUS INTERRUPTUS REFINED AT 3.2 ANGSTROMS RESOLUTION
分子名称: ARTHROPODAN HEMOCYANIN, COPPER (II) ION
著者Volbeda, A, Hol, W.G.J.
登録日1991-05-15
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of hexameric haemocyanin from Panulirus interruptus refined at 3.2 A resolution.
J.Mol.Biol., 209, 1989
1HCY
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BU of 1hcy by Molmil
CRYSTAL STRUCTURE OF HEXAMERIC HAEMOCYANIN FROM PANULIRUS INTERRUPTUS REFINED AT 3.2 ANGSTROMS RESOLUTION
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ARTHROPODAN HEMOCYANIN, COPPER (II) ION
著者Volbeda, A, Hol, W.G.J.
登録日1991-05-15
公開日1994-01-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of hexameric haemocyanin from Panulirus interruptus refined at 3.2 A resolution.
J.Mol.Biol., 209, 1989
6IG8
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BU of 6ig8 by Molmil
Crystal structure of CSF-1R kinase domain with a small molecular inhibitor, JTE-952
分子名称: (3-{4-[(4-cyclopropylphenyl)methoxy]-3-methoxyphenyl}azetidin-1-yl)(4-{[(2S)-2,3-dihydroxypropoxy]methyl}pyridin-2-yl)methanone, GLYCEROL, MAGNESIUM ION, ...
著者Doi, S, Adachi, T.
登録日2018-09-25
公開日2019-08-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery of a novel azetidine scaffold for colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors by the use of docking models.
Bioorg.Med.Chem.Lett., 29, 2019
1UGN
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BU of 1ugn by Molmil
Crystal structure of LIR1.02, one of the alleles of LIR1
分子名称: Leukocyte immunoglobulin-like receptor 1
著者Shiroishi, M, Rasubala, L, Kuroki, K, Amano, K, Tsuchiya, N, Tokunaga, K, Kohda, D, Maenaka, K.
登録日2003-06-17
公開日2004-08-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Extensive polymorphisms of LILRB1 (ILT2, LIR1) and their association with HLA-DRB1 shared epitope negative rheumatoid arthritis.
Hum.Mol.Genet., 14, 2005
4X9J
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BU of 4x9j by Molmil
EGR-1 with Doubly Methylated DNA
分子名称: DNA (5'-D(*AP*GP*(5CM)P*GP*TP*GP*GP*GP*(5CM)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*(5CM)P*GP*C)-3'), Early growth response protein 1, ...
著者White, M.A, Zandarashvili, L, Iwahara, J.
登録日2014-12-11
公開日2015-05-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.412 Å)
主引用文献Structural impact of complete CpG methylation within target DNA on specific complex formation of the inducible transcription factor Egr-1.
Febs Lett., 589, 2015
4XIC
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BU of 4xic by Molmil
ANTPHD WITH 15BP di-thioate modified DNA DUPLEX
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*(C2S)P*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ...
著者White, M.A, Zandarashvili, L, Iwahara, J.
登録日2015-01-06
公開日2015-11-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Entropic Enhancement of Protein-DNA Affinity by Oxygen-to-Sulfur Substitution in DNA Phosphate.
Biophys.J., 109, 2015
1RGN
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BU of 1rgn by Molmil
Structure of the reaction centre from Rhodobacter sphaeroides carotenoidless strain R-26.1 reconstituted with spheroidene
分子名称: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (III) ION, ...
著者Roszak, A.W, Frank, H.A, McKendrick, K, Mitchell, I.A, Cogdell, R.J, Isaacs, N.W.
登録日2003-11-12
公開日2004-04-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Protein Regulation of Carotenoid Binding: Gatekeeper and Locking Amino Acid Residues in Reaction Centers of Rhodobacter sphaeroides
STRUCTURE, 12, 2004
2ZJ3
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BU of 2zj3 by Molmil
Isomerase domain of human glucose:fructose-6-phosphate amidotransferase
分子名称: 6-O-phosphono-alpha-D-glucopyranose, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
著者Nakaishi, Y, Bando, M, Kondo, K, Tsuge, H.
登録日2008-02-29
公開日2009-01-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of human glutamine:fructose-6-phosphate amidotransferase, a key regulator in type 2 diabetes
Febs Lett., 583, 2009
2ZJ4
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BU of 2zj4 by Molmil
Isomerase domain of human glucose:fructose-6-phosphate amidotransferase
分子名称: 2-DEOXY-2-AMINO GLUCITOL-6-PHOSPHATE, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
著者Nakaishi, Y, Bando, M, Kondo, K, Tsuge, H.
登録日2008-02-29
公開日2009-01-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural analysis of human glutamine:fructose-6-phosphate amidotransferase, a key regulator in type 2 diabetes
Febs Lett., 583, 2009
1N5X
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BU of 1n5x by Molmil
Xanthine Dehydrogenase from Bovine Milk with Inhibitor TEI-6720 Bound
分子名称: 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE-CARBOXYLIC ACID, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ...
著者Okamoto, K, Eger, B.T, Nishino, T, Kondo, S, Pai, E.F, Nishino, T.
登録日2002-11-07
公開日2003-03-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献An Extremely Potent Inhibitor of Xanthine Oxidoreductase: Crystal Structure of the Enzyme-Inhibitor Complex and Mechanism of Inhibition
J.BIOL.CHEM., 278, 2003
1NOL
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BU of 1nol by Molmil
OXYGENATED HEMOCYANIN (SUBUNIT TYPE II)
分子名称: CALCIUM ION, COPPER (II) ION, HEMOCYANIN (SUBUNIT TYPE II), ...
著者Hazes, B, Hol, W.G.J.
登録日1995-10-17
公開日1996-03-08
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of deoxygenated Limulus polyphemus subunit II hemocyanin at 2.18 A resolution: clues for a mechanism for allosteric regulation.
Protein Sci., 2, 1993
7WKZ
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BU of 7wkz by Molmil
Crystal structure of the HSA complex with mycophenolate and aripiprazole
分子名称: 7-[4-[4-[2,3-bis(chloranyl)phenyl]piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one, MYCOPHENOLIC ACID, Serum albumin
著者Kawai, A, Yamasaki, K.
登録日2022-01-12
公開日2022-12-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.992 Å)
主引用文献Structural Basis of the Change in the Interaction Between Mycophenolic Acid and Subdomain IIA of Human Serum Albumin During Renal Failure.
J.Med.Chem., 66, 2023
5ZFU
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BU of 5zfu by Molmil
Structure of the ExbB/ExbD hexameric complex (ExbB6ExbD3TM)
分子名称: 22-mer peptide from Biopolymer transport protein ExbD, Biopolymer transport protein ExbB
著者Yonekura, K, Yamashita, Y, Matsuoka, R, Maki-Yonekura, S.
登録日2018-03-07
公開日2018-05-09
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献Hexameric and pentameric complexes of the ExbBD energizer in the Ton system.
Elife, 7, 2018
5ZFP
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BU of 5zfp by Molmil
Structure of the ExbB/ExbD hexameric complex
分子名称: Biopolymer transport protein ExbB
著者Maki-Yonekura, S, Matsuoka, R, Yonekura, K.
登録日2018-03-06
公開日2018-05-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Hexameric and pentameric complexes of the ExbBD energizer in the Ton system.
Elife, 7, 2018
5ZFV
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BU of 5zfv by Molmil
Structure of the ExbB/ExbD pentameric complex (ExbB5ExbD1TM)
分子名称: 22-mer peptide from Biopolymer transport protein ExbD, Biopolymer transport protein ExbB
著者Yonekura, K, Yamashita, Y, Matsuoka, R, Maki-Yonekura, S.
登録日2018-03-07
公開日2018-05-09
実験手法ELECTRON MICROSCOPY (7.1 Å)
主引用文献Hexameric and pentameric complexes of the ExbBD energizer in the Ton system.
Elife, 7, 2018
3AM2
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BU of 3am2 by Molmil
Clostridium perfringens enterotoxin
分子名称: GLYCEROL, Heat-labile enterotoxin B chain, UNKNOWN ATOM OR ION
著者Kitadokoro, K, Nishimura, K, Kamitani, S, Kimura, J, Fukui, A, Abe, H, Horiguchi, Y.
登録日2010-08-12
公開日2011-04-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Crystal Structure of Clostridium perfringens Enterotoxin Displays Features of {beta}-Pore-forming Toxins
J.Biol.Chem., 286, 2011
3WPN
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BU of 3wpn by Molmil
Kinesin spindle protein Eg5 in complex with ATP-competitive inhibitor PVZB1194
分子名称: 3'-fluoro-4'-(trifluoromethyl)biphenyl-4-sulfonamide, Kinesin-like protein KIF11
著者Yokoyama, H, Katoh, S, Fujii, S.
登録日2014-01-14
公開日2015-01-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of new allosteric inhibition in Kinesin spindle protein eg5
Acs Chem.Biol., 10, 2015
7DCF
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BU of 7dcf by Molmil
Crystal structure of EHMT2 SET domain in complex with compound 10
分子名称: 5'-methoxy-6'-(1-methyl-2,3,4,7-tetrahydroazepin-5-yl)spiro[cyclobutane-1,3'-indole]-2'-amine, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ...
著者Suzuki, M, Katayama, K.
登録日2020-10-26
公開日2021-02-10
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery of DS79932728: A Potent, Orally Available G9a/GLP Inhibitor for Treating beta-Thalassemia and Sickle Cell Disease.
Acs Med.Chem.Lett., 12, 2021
1LLA
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BU of 1lla by Molmil
CRYSTAL STRUCTURE OF DEOXYGENATED LIMULUS POLYPHEMUS SUBUNIT II HEMOCYANIN AT 2.18 ANGSTROMS RESOLUTION: CLUES FOR A MECHANISM FOR ALLOSTERIC REGULATION
分子名称: CHLORIDE ION, COPPER (II) ION, HEMOCYANIN (SUBUNIT TYPE II), ...
著者Hazes, B, Hol, W.G.J.
登録日1992-09-07
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Crystal structure of deoxygenated Limulus polyphemus subunit II hemocyanin at 2.18 A resolution: clues for a mechanism for allosteric regulation.
Protein Sci., 2, 1993
3AIX
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BU of 3aix by Molmil
Crystal structure of PCNA2-PCNA3 complex from Sulfolobus tokodaii (I222)
分子名称: DNA polymerase sliding clamp B, DNA polymerase sliding clamp C, SULFATE ION
著者Kawai, A, Higuchi, S, Miyamoto, S.
登録日2010-05-18
公開日2011-05-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A novel heterotetrameric structure of the crenarchaeal PCNA2-PCNA3 complex
J.Struct.Biol., 174, 2011
3AIZ
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BU of 3aiz by Molmil
Crystal structure of PCNA2-PCNA3 complex from Sulfolobus tokodaii (P21212)
分子名称: DNA polymerase sliding clamp B, DNA polymerase sliding clamp C, SULFATE ION
著者Kawai, A, Higuchi, S, Miyamoto, S.
登録日2010-05-18
公開日2011-05-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A novel heterotetrameric structure of the crenarchaeal PCNA2-PCNA3 complex
J.Struct.Biol., 174, 2011
2DXS
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BU of 2dxs by Molmil
Crystal structure of HCV NS5B RNA polymerase complexed with a tetracyclic inhibitor
分子名称: Genome polyprotein, N-[(13-CYCLOHEXYL-6,7-DIHYDROINDOLO[1,2-D][1,4]BENZOXAZEPIN-10-YL)CARBONYL]-2-METHYL-L-ALANINE
著者Adachi, T, Tsuruha, J, Doi, S, Murase, K, Ikegashira, K, Watanabe, S, Uehara, K, Orita, T, Nomura, A, Kamada, M.
登録日2006-08-30
公開日2006-12-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of Conformationally Constrained Tetracyclic Compounds as Potent Hepatitis C Virus NS5B RNA Polymerase Inhibitors
J.Med.Chem., 49, 2006

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