7WUQ
 
 | | Tethered peptide activation mechanism of adhesion GPCRs ADGRG2 and ADGRG4 | | 分子名称: | Adhesion G-protein coupled receptor G2,mCherry, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | He, Q.T, Guo, S.C, Xiao, P, Sun, J.P, Yu, X, Gou, L, Kong, L.L, Zhang, L. | | 登録日 | 2022-02-09 | | 公開日 | 2022-04-27 | | 最終更新日 | 2022-05-11 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4.
Nature, 604, 2022
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6FTU
 | | Structure of a Quadruplex forming sequence from D. discoideum | | 分子名称: | DNA (26-MER), POTASSIUM ION | | 著者 | Guedin, A, Linda, L, Armane, S, Lacroix, L, Mergny, J.L, Thore, S, Yatsunyk, L.A. | | 登録日 | 2018-02-23 | | 公開日 | 2018-04-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Quadruplexes in 'Dicty': crystal structure of a four-quartet G-quadruplex formed by G-rich motif found in the Dictyostelium discoideum genome.
Nucleic Acids Res., 46, 2018
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1YI3
 | | Crystal Structure of Pim-1 bound to LY294002 | | 分子名称: | 2-MORPHOLIN-4-YL-7-PHENYL-4H-CHROMEN-4-ONE, Proto-oncogene serine/threonine-protein kinase Pim-1 | | 著者 | Jacobs, M.D, Black, J, Futer, O, Swenson, L, Hare, B, Fleming, M, Saxena, K. | | 登録日 | 2005-01-11 | | 公開日 | 2005-01-25 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Pim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002.
J.Biol.Chem., 280, 2005
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6JCY
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3G39
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1ZJD
 | | Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with Kunitz Protease Inhibitor Domain of Protease Nexin II | | 分子名称: | Catalytic Domain of Coagulation Factor XI, Kunitz Protease Inhibitory Domain of Protease Nexin II | | 著者 | Jin, L, Navaneetham, D, Pandey, P, Strickler, J.E, Babine, R.E, Walsh, P.N, Abdel-Meguid, S.S. | | 登録日 | 2005-04-28 | | 公開日 | 2005-08-09 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and Mutational Analyses of the Molecular Interactions between the Catalytic Domain of Factor XIa and the Kunitz Protease Inhibitor Domain of Protease Nexin 2
J.Biol.Chem., 280, 2005
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7PLQ
 | | Crystal structure of the PARP domain of wheat SRO1 | | 分子名称: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, GLYCEROL, ... | | 著者 | Wirthmueller, L, Loll, B. | | 登録日 | 2021-09-01 | | 公開日 | 2021-10-27 | | 最終更新日 | 2022-11-09 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | The superior salinity tolerance of bread wheat cultivar Shanrong No. 3 is unlikely to be caused by elevated Ta-sro1 poly-(ADP-ribose) polymerase activity.
Plant Cell, 34, 2022
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1ZPX
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6HSW
 | | A CE15 glucuronoyl esterase from Teredinibacter turnerae T7901 | | 分子名称: | 1,2-ETHANEDIOL, BROMIDE ION, Carbohydrate esterase family 15 domain protein, ... | | 著者 | Mazurkewich, S, Lo Leggio, L, Navarro Poulsen, J.C, Larsbrink, J. | | 登録日 | 2018-10-02 | | 公開日 | 2019-03-20 | | 最終更新日 | 2019-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.14734387 Å) | | 主引用文献 | Structure-function analyses reveal that a glucuronoyl esterase fromTeredinibacter turneraeinteracts with carbohydrates and aromatic compounds.
J.Biol.Chem., 294, 2019
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1XXS
 | | Structural insights for fatty acid binding in a Lys49 phospholipase A2: crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid | | 分子名称: | Phospholipase A2 homolog 2, STEARIC ACID, SULFATE ION | | 著者 | Watanabe, L, Soares, A.M, Ward, R.J, Fontes, M.R, Arni, R.K. | | 登録日 | 2004-11-08 | | 公開日 | 2005-03-29 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights for fatty acid binding in a Lys49-phospholipase A(2): crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid
Biochimie, 87, 2005
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6HA5
 | | AFGH61B L90V/D131S/M134L/A141W VARIANT | | 分子名称: | ACETATE ION, COPPER (II) ION, Endoglucanase, ... | | 著者 | Lo Leggio, L, Poulsen, J.C.N. | | 登録日 | 2018-08-07 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Structure of a lytic polysaccharide monooxygenase from Aspergillus fumigatus and an engineered thermostable variant.
Carbohydr. Res., 469, 2018
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1XOC
 | | The structure of the oligopeptide-binding protein, AppA, from Bacillus subtilis in complex with a nonapeptide. | | 分子名称: | Nonapeptide VDSKNTSSW, Oligopeptide-binding protein appA, ZINC ION | | 著者 | Levdikov, V.M, Blagova, E.V, Brannigan, J.A, Wright, L, Vagin, A.A, Wilkinson, A.J. | | 登録日 | 2004-10-06 | | 公開日 | 2005-01-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | The structure of the oligopeptide-binding protein, AppA, from Bacillus subtilis in complex with a nonapeptide.
J.Mol.Biol., 345, 2005
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6KIG
 | | Structure of cyanobacterial photosystem I-IsiA supercomplex | | 分子名称: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | | 著者 | Cao, P, Cao, D.F, Si, L, Su, X.D, Chang, W.R, Liu, Z.F, Zhang, X.Z, Li, M. | | 登録日 | 2019-07-18 | | 公開日 | 2020-02-12 | | 最終更新日 | 2020-03-04 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis for energy and electron transfer of the photosystem I-IsiA-flavodoxin supercomplex.
Nat.Plants, 6, 2020
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4CC3
 | | Complex of human Tuba C-terminal SH3 domain and Mena proline-rich peptide - H3 | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, CHLORIDE ION, DYNAMIN-BINDING PROTEIN, ... | | 著者 | Polle, L, Rigano, L, Julian, R, Ireton, K, Schubert, W.-D. | | 登録日 | 2013-10-17 | | 公開日 | 2013-10-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structural Details of Human Tuba Recruitment by Inlc of Listeria Monocytogenes Elucidate Bacterial Cell-Cell Spreading.
Structure, 22, 2014
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4CC7
 | | Crystal structure of the sixth or C-terminal SH3 domain of human Tuba in complex with proline-rich peptides of N-WASP. Space group P41 | | 分子名称: | CHLORIDE ION, DYNAMIN-BINDING PROTEIN, GLYCEROL, ... | | 著者 | Polle, L, Rigano, L, Julian, R, Ireton, K, Schubert, W.-D. | | 登録日 | 2013-10-18 | | 公開日 | 2013-10-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structural Details of Human Tuba Recruitment by Inlc of Listeria Monocytogenes Elucidate Bacterial Cell-Cell Spreading.
Structure, 22, 2014
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223D
 | | DIRECT OBSERVATION OF TWO BASE-PAIRING MODES OF A CYTOSINE-THYMINE ANALOGUE WITH GUANINE IN A DNA Z-FORM DUPLEX: SIGNIFICANCE FOR BASE ANALOGUE MUTAGENESIS | | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*(C46)P*G)-3') | | 著者 | Moore, M.H, Van Meervelt, L, Salisbury, S.A, Kong Thoo Lin, P, Brown, D.M. | | 登録日 | 1995-08-01 | | 公開日 | 1995-12-09 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Direct observation of two base-pairing modes of a cytosine-thymine analogue with guanine in a DNA Z-form duplex: significance for base analogue mutagenesis.
J.Mol.Biol., 251, 1995
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3H0F
 | | Crystal structure of the human Fyn SH3 R96W mutant | | 分子名称: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, Proto-oncogene tyrosine-protein kinase Fyn | | 著者 | Ponchon, L, Hoh, F, Labesse, G, Dumas, C, Arold, S.T. | | 登録日 | 2009-04-09 | | 公開日 | 2010-04-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
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6KIF
 | | Structure of cyanobacterial photosystem I-IsiA-flavodoxin supercomplex | | 分子名称: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | | 著者 | Cao, P, Cao, D.F, Si, L, Su, X.D, Chang, W.R, Liu, Z.F, Zhang, X.Z, Li, M. | | 登録日 | 2019-07-18 | | 公開日 | 2020-02-12 | | 最終更新日 | 2020-03-04 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis for energy and electron transfer of the photosystem I-IsiA-flavodoxin supercomplex.
Nat.Plants, 6, 2020
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1YHS
 | | Crystal structure of Pim-1 bound to staurosporine | | 分子名称: | Proto-oncogene serine/threonine-protein kinase Pim-1, STAUROSPORINE | | 著者 | Jacobs, M.D, Black, J, Futer, O, Swenson, L, Hare, B, Fleming, M, Saxena, K. | | 登録日 | 2005-01-10 | | 公開日 | 2005-01-25 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Pim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002.
J.Biol.Chem., 280, 2005
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5OTM
 | | Crystal structure of human MTH1 in complex with O6-methyl-dGMP | | 分子名称: | 6-O-METHYL GUANOSINE-5'-MONOPHOSPHATE, 7,8-dihydro-8-oxoguanine triphosphatase, ACETATE ION, ... | | 著者 | Gustafsson, R, Henriksson, L, Jemth, A.-S, Brautigam, L, Carreras Puigvert, J, Homan, E, Warpman Berglund, U, Helleday, T, Stenmark, P. | | 登録日 | 2017-08-22 | | 公開日 | 2018-09-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | MutT homologue 1 (MTH1) catalyzes the hydrolysis of mutagenic O6-methyl-dGTP.
Nucleic Acids Res., 46, 2018
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208D
 | | HIGH-RESOLUTION STRUCTURE OF A DNA HELIX FORMING (C.G)*G BASE TRIPLETS | | 分子名称: | DNA (5'-D(*GP*CP*GP*AP*AP*TP*TP*CP*G)-3'), MAGNESIUM ION | | 著者 | Van Meervelt, L, Vlieghe, D, Dautant, A, Gallois, B, Precigoux, G, Kennard, O. | | 登録日 | 1995-04-26 | | 公開日 | 1995-09-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | High-resolution structure of a DNA helix forming (C.G)*G base triplets.
Nature, 374, 1995
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2A45
 | | Crystal structure of the complex between thrombin and the central "E" region of fibrin | | 分子名称: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Fibrinogen alpha chain, Fibrinogen beta chain, ... | | 著者 | Pechik, I, Madrazo, J, Gilliland, G.L, Medved, L. | | 登録日 | 2005-06-27 | | 公開日 | 2006-05-02 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | | 主引用文献 | Structural basis for sequential cleavage of fibrinopeptides upon fibrin assembly.
Biochemistry, 45, 2006
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6KPF
 | | Cryo-EM structure of a class A GPCR with G protein complex | | 分子名称: | 7-[(6aR,9R,10aR)-1-Hydroxy-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromen-3-yl]- 7-methyloctanenitrile, Cannabinoid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Li, X.T, Hua, T, Wu, L.J, Makriyannis, A, Shen, L, Wang, Y.X, Liu, Z.J. | | 登録日 | 2019-08-15 | | 公開日 | 2020-02-12 | | 最終更新日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-GiComplex Structures.
Cell, 180, 2020
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3H0Q
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2AAD
 | | THE ROLE OF HISTIDINE-40 IN RIBONUCLEASE T1 CATALYSIS: THREE-DIMENSIONAL STRUCTURES OF THE PARTIALLY ACTIVE HIS40LYS MUTANT | | 分子名称: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1 ISOZYME | | 著者 | Zegers, I, Verhelst, P, Choe, C.W, Steyaert, J, Heinemann, U, Wyns, L, Saenger, W. | | 登録日 | 1992-09-15 | | 公開日 | 1994-01-31 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Role of histidine-40 in ribonuclease T1 catalysis: three-dimensionalstructures of the partially active His40Lys mutant.
Biochemistry, 31, 1992
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