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2GQM
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BU of 2gqm by Molmil
Solution structure of Human Cu(I)-Sco1
分子名称: COPPER (I) ION, SCO1 protein homolog, mitochondrial
著者Banci, L, Bertini, I, Calderone, V, Ciofi-Baffoni, S, Mangani, S, Palumaa, P, Martinelli, M, Wang, S, Structural Proteomics in Europe (SPINE)
登録日2006-04-21
公開日2006-06-06
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A hint for the function of human Sco1 from different structures.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3IZJ
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BU of 3izj by Molmil
Mm-cpn rls with ATP and AlFx
分子名称: Chaperonin
著者Douglas, N.R, Reissmann, S, Zhang, J, Chen, B, Jakana, J, Kumar, R, Chiu, W, Frydman, J.
登録日2010-10-29
公開日2011-02-02
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献Dual Action of ATP Hydrolysis Couples Lid Closure to Substrate Release into the Group II Chaperonin Chamber.
Cell(Cambridge,Mass.), 144, 2011
2GQL
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BU of 2gql by Molmil
Solution structure of Human Ni(II)-Sco1
分子名称: NICKEL (II) ION, SCO1 protein homolog, mitochondrial
著者Banci, L, Bertini, I, Calderone, V, Ciofi-Baffoni, S, Mangani, S, Palumaa, P, Martinelli, M, Wang, S, Structural Proteomics in Europe (SPINE)
登録日2006-04-21
公開日2006-06-06
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A hint for the function of human Sco1 from different structures.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3N30
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BU of 3n30 by Molmil
Crystal Structure of cubic Zn3-hUb (human ubiquitin) adduct
分子名称: Ubiquitin, ZINC ION
著者Siliqi, D, Caliandro, R, Arnesano, F, Natile, G, Falini, G, Fermani, S, Belviso, B.D.
登録日2010-05-19
公開日2011-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystallographic analysis of metal-ion binding to human ubiquitin.
Chemistry, 17, 2011
3LOS
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BU of 3los by Molmil
Atomic Model of Mm-cpn in the Closed State
分子名称: Chaperonin
著者Zhang, J, Baker, M.L, Schroeder, G, Douglas, N.R, Reissmann, S, Jakana, J, Dougherty, M, Fu, C.J, Levitt, M, Ludtke, S.J, Frydman, J, Chiu, W.
登録日2010-02-04
公開日2010-03-16
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Mechanism of folding chamber closure in a group II chaperonin
Nature, 463, 2010
6ZXO
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BU of 6zxo by Molmil
Crystal structure of His-tagged human thymidylate synthase (HT-hTS) in complex with FdUMP and Raltitrexed (Tomudex)
分子名称: 1,2-ETHANEDIOL, 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, TOMUDEX, ...
著者Pozzi, C, Mangani, S.
登録日2020-07-30
公開日2021-05-19
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Bases for the Synergistic Inhibition of Human Thymidylate Synthase and Ovarian Cancer Cell Growth by Drug Combinations.
Cancers (Basel), 13, 2021
3N32
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BU of 3n32 by Molmil
The crystal structure of human Ubiquitin adduct with Zeise's salt
分子名称: PLATINUM (II) ION, Ubiquitin
著者Siliqi, D, Caliandro, R, Falini, G, Fermani, S, Natile, G, Arnesano, F, Belviso, B.D.
登録日2010-05-19
公開日2011-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.795 Å)
主引用文献Crystallographic analysis of metal-ion binding to human ubiquitin.
Chemistry, 17, 2011
6HF5
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BU of 6hf5 by Molmil
Crystal Structure of the Acquired VIM-2 Metallo-beta-Lactamase in Complex with ANT-431 Inhibitor
分子名称: 5-(pyridin-3-ylsulfonylamino)-1,3-thiazole-4-carboxylic acid, ACETATE ION, Beta-lactamase class B VIM-2, ...
著者Docquier, J.D, Pozzi, C, De Luca, F, Benvenuti, M, Mangani, S.
登録日2018-08-21
公開日2018-12-05
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献SAR Studies Leading to the Identification of a Novel Series of Metallo-beta-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model.
Acs Infect Dis., 5, 2019
3U4R
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BU of 3u4r by Molmil
Novel HCV NS5B polymerase Inhibitors: Discovery of Indole C2 Acyl sulfonamides
分子名称: 1-[(2-aminopyridin-4-yl)methyl]-5-chloro-N-({3-[(methylsulfonyl)amino]phenyl}sulfonyl)-3-(2-oxo-1,2-dihydropyridin-3-yl)-1H-indole-2-carboxamide, RNA-directed RNA polymerase
著者Anilkumar, G.N, Selyutin, O, Rosenblum, S.B, Zeng, Q, Jiang, Y, Chan, T.-Y, Pu, H, Wang, L, Bennett, F, Chen, K.X, Lesburg, C.A, Duca, J.S, Gavalas, S, Huang, Y, Pinto, P, Sannagrahi, M, Velazquez, F, Venkataraman, S, Vilbubhan, B, Agrawal, S, Ferrari, E, Jiang, C.-K, Huang, H.-C, Shih, N.-Y, Njoroge, F.G, Kozlowski, J.A.
登録日2011-10-10
公開日2011-12-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献II. Novel HCV NS5B polymerase inhibitors: Discovery of indole C2 acyl sulfonamides.
Bioorg.Med.Chem.Lett., 22, 2012
3U4O
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BU of 3u4o by Molmil
Novel HCV NS5B polymerase Inhibitors: Discovery of Indole C2 Acyl sulfonamides
分子名称: 1-[(2-aminopyridin-4-yl)methyl]-5-chloro-3-(2-oxo-1,2-dihydropyridin-3-yl)-1H-indole-2-carboxylic acid, PHOSPHATE ION, RNA-directed RNA polymerase
著者Anilkumar, G.N, Selyutin, O, Rosenblum, S.B, Zeng, Q, Jiang, Y, Chan, T.-Y, Pu, H, Wang, L, Bennett, F, Chen, K.X, Lesburg, C.A, Duca, J.S, Gavalas, S, Huang, Y, Pinto, P, Sannigrahi, M, Velazquez, F, Venkataraman, S, Vilbubhan, B, Agrawal, S, Ferrari, E, Jiang, C.-K, Huang, H.-C, Shih, N.-Y, Njoroge, F.G, Kozlowski, J.A.
登録日2011-10-10
公開日2011-12-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献II. Novel HCV NS5B polymerase inhibitors: Discovery of indole C2 acyl sulfonamides.
Bioorg.Med.Chem.Lett., 22, 2012
2YII
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BU of 2yii by Molmil
Manipulating the regioselectivity of phenylalanine aminomutase: new insights into the reaction mechanism of MIO-dependent enzymes from structure-guided directed evolution
分子名称: BETA-MERCAPTOETHANOL, FORMIC ACID, GLYCEROL, ...
著者Wu, B, Szymanski, W, Wybenga, G.G, Heberling, M.M, Bartsch, S, Wildeman, S, Poelarends, G.J, Feringa, B.L, Dijkstra, B.W, Janssen, D.B.
登録日2011-05-13
公開日2011-11-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Mechanism-Inspired Engineering of Phenylalanine Aminomutase for Enhanced Beta-Regioselective Asymmetric Amination of Cinnamates.
Angew.Chem.Int.Ed.Engl., 51, 2012
3P43
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BU of 3p43 by Molmil
Structure and Activities of Archaeal Members of the LigD 3' Phosphoesterase DNA Repair Enzyme Superfamily
分子名称: CHLORIDE ION, MANGANESE (II) ION, PHOSPHATE ION, ...
著者Smith, P, Nair, P.A, Das, U, Shuman, S.
登録日2010-10-05
公開日2011-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures and activities of archaeal members of the LigD 3'-phosphoesterase DNA repair enzyme superfamily.
Nucleic Acids Res., 39, 2011
2GVP
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BU of 2gvp by Molmil
Solution structure of Human apo Sco1
分子名称: SCO1 protein homolog, mitochondrial
著者Banci, L, Bertini, I, Calderone, V, Ciofi-Baffoni, S, Mangani, S, Paulmaa, P, Martinelli, M, Wang, S, Structural Proteomics in Europe (SPINE)
登録日2006-05-03
公開日2006-06-06
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A hint for the function of human Sco1 from different structures.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2GT5
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BU of 2gt5 by Molmil
Solution structure of apo Human Sco1
分子名称: SCO1 protein homolog, mitochondrial
著者Banci, L, Bertini, I, Calderone, V, Ciofi-Baffoni, S, Mangani, S, Palumaa, P, Martinelli, M, Wang, S, Structural Proteomics in Europe (SPINE)
登録日2006-04-27
公開日2006-06-06
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A hint for the function of human Sco1 from different structures.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2GT6
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BU of 2gt6 by Molmil
Solution structure of Human Cu(I) Sco1
分子名称: COPPER (I) ION, SCO1 protein homolog, mitochondrial
著者Banci, L, Bertini, I, Calderone, V, Ciofi-Baffoni, S, Mangani, S, Palumaa, P, Martinelli, M, Wang, S, Structural Proteomics in Europe (SPINE)
登録日2006-04-27
公開日2006-06-06
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A hint for the function of human Sco1 from different structures.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1NBO
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BU of 1nbo by Molmil
The dual coenzyme specificity of photosynthetic glyceraldehyde-3-phosphate dehydrogenase interpreted by the crystal structure of A4 isoform complexed with NAD
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, glyceraldehyde-3-phosphate dehydrogenase A
著者Falini, G, Fermani, S, Ripamonti, A, Sabatino, P, Sparla, F, Pupillo, P, Trost, P.
登録日2002-12-03
公開日2003-05-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Dual Coenzyme Specificity of Photosynthetic Glyceraldehyde-3-phosphate Dehydrogenase Interpreted by the Crystal Structure of A(4) Isoform Complexed with NAD
Biochemistry, 42, 2003
6XZF
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BU of 6xzf by Molmil
Nanobody in complex with eGFP
分子名称: Nanobody targeted against eGFP, TERBIUM(III) ION, eGFP
著者Pompidor, G, Zimmermann, S, Loew, C, Schneider, T.
登録日2020-02-04
公開日2021-02-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Engineered nanobodies with a lanthanide binding motif for crystallographic phasing
To Be Published
6XYF
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BU of 6xyf by Molmil
Nanobody 22
分子名称: Nanobody 22, SODIUM ION
著者Pompidor, G, Zimmermann, S, Loew, C, Schneider, T.
登録日2020-01-30
公開日2021-02-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.11097 Å)
主引用文献Engineered nanobodies with a lanthanide binding motif for crystallographic phasing
To Be Published
6XYM
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BU of 6xym by Molmil
Nbe-LBM
分子名称: Nbe-LBM, TERBIUM(III) ION
著者Pompidor, G, Zimmermann, S, Loew, C, Schneider, T.
登録日2020-01-30
公開日2021-02-10
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Engineered nanobodies with a lanthanide binding motif for crystallographic phasing
To Be Published
1SNN
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BU of 1snn by Molmil
3,4-dihydroxy-2-butanone 4-phosphate synthase from Methanococcus jannaschii
分子名称: 3,4-dihydroxy-2-butanone 4-phosphate synthase, CALCIUM ION, RIBULOSE-5-PHOSPHATE, ...
著者Steinbacher, S, Schiffmann, S, Huber, R, Bacher, A, Fischer, M.
登録日2004-03-11
公開日2004-07-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Metal sites in 3,4-dihydroxy-2-butanone 4-phosphate synthase from Methanococcus jannaschii in complex with the substrate ribulose 5-phosphate.
Acta Crystallogr.,Sect.D, 60, 2004
8A5Q
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BU of 8a5q by Molmil
Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80 on straight DNA
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin related protein 4 (Arp4), ...
著者Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P.
登録日2022-06-15
公開日2022-12-14
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
8A5P
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BU of 8a5p by Molmil
Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80 on curved DNA
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin related protein 4 (Arp4), ...
著者Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P.
登録日2022-06-15
公開日2022-12-14
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
8A5A
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BU of 8a5a by Molmil
Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of INO80
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-like protein ARP8, ...
著者Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P.
登録日2022-06-14
公開日2022-12-14
最終更新日2023-03-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
8A5D
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BU of 8a5d by Molmil
Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80
分子名称: Actin, Actin related protein 4 (Arp4), Actin-related protein 8, ...
著者Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P.
登録日2022-06-14
公開日2022-12-28
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
2YXR
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BU of 2yxr by Molmil
The plug domain of the SecY protein stablizes the closed state of the translocation channel and maintains a membrane seal
分子名称: Preprotein translocase secG subunit, Preprotein translocase subunit secE, Preprotein translocase subunit secY
著者Li, W, Schulman, S.
登録日2007-04-27
公開日2007-08-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献The plug domain of the SecY protein stabilizes the closed state of the translocation channel and maintains a membrane seal
Mol.Cell, 26, 2007

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