8H00
 
 | | SARS-CoV-2 Omicron BA.1 Spike glycoprotein in complex with rabbit monoclonal antibody 1H1 Fab in the class 1 conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X. | | 登録日 | 2022-09-27 | | 公開日 | 2023-04-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants.
Commun Biol, 6, 2023
|
|
8H01
 | | SARS-CoV-2 Omicron BA.1 Spike glycoprotein in complex with rabbit monoclonal antibody 1H1 Fab in class 2 conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X. | | 登録日 | 2022-09-27 | | 公開日 | 2023-04-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants.
Commun Biol, 6, 2023
|
|
4PQ6
 | |
4PQB
 | |
5TOZ
 | | JAK3 with covalent inhibitor PF-06651600 | | 分子名称: | 1-{(2S,5R)-2-methyl-5-[(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}propan-1-one, SULFATE ION, Tyrosine-protein kinase JAK3 | | 著者 | Vajdos, F.F. | | 登録日 | 2016-10-19 | | 公開日 | 2016-11-09 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition.
ACS Chem. Biol., 11, 2016
|
|
7XPQ
 | |
7XPO
 | | Crystal Structure of UDP-Glc/GlcNAc 4-Epimerase with NAD/UDP-Glc | | 分子名称: | GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase, ... | | 著者 | Chen, Y.H, Wang, X.C, Zhang, C.R. | | 登録日 | 2022-05-05 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | A maize epimerase modulates cell wall synthesis and glycosylation during stomatal morphogenesis.
Nat Commun, 14, 2023
|
|
7XPP
 | |
6OQ3
 | |
8IQF
 | | Cryo-EM structure of the dimeric human CAF1-H3-H4 complex | | 分子名称: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ... | | 著者 | Liu, C.P, Yu, Z.Y, Xu, R.M. | | 登録日 | 2023-03-16 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
|
|
8IQG
 | | Cryo-EM structure of the monomeric human CAF1-H3-H4 complex | | 分子名称: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ... | | 著者 | Liu, C.P, Yu, Z.Y, Xu, R.M. | | 登録日 | 2023-03-16 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
|
|
6OQ4
 | |
4PQC
 | |
1P6B
 | | X-ray structure of phosphotriesterase, triple mutant H254G/H257W/L303T | | 分子名称: | DIETHYL 4-METHYLBENZYLPHOSPHONATE, ETHYL DIHYDROGEN PHOSPHATE, Parathion hydrolase, ... | | 著者 | Hill, C.M, Li, W, Thoden, J.B, Holden, H.M, Raushel, F.M. | | 登録日 | 2003-04-29 | | 公開日 | 2003-09-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Enhanced degradation of chemical warfare agents through molecular engineering of the phosphotriesterase active site.
J.Am.Chem.Soc., 125, 2003
|
|
8IG7
 | |
8IG8
 | |
8IG5
 | | Crystal structure of SARS main protease in complex with GC376 | | 分子名称: | 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide | | 著者 | Lin, C, Zhang, J, Li, J. | | 登録日 | 2023-02-20 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
|
|
8IG4
 | |
8IG9
 | |
8IG6
 | |
8IGA
 | |
6A40
 | | complex structure of Alginate lyase AlyF-OU02 with G4 | | 分子名称: | alginate lyase AlyF-OU02, alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid | | 著者 | Liu, W.Z, Lyu, Q.Q, Zhang, K.K. | | 登録日 | 2018-06-18 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights into a novel Ca2+-independent PL-6 alginate lyase from Vibrio OU02 identify the possible subsites responsible for product distribution.
Biochim Biophys Acta Gen Subj, 1863, 2019
|
|
1P6C
 | | crystal structure of phosphotriesterase triple mutant H254G/H257W/L303T complexed with diisopropylmethylphosphonate | | 分子名称: | DIETHYL 4-METHYLBENZYLPHOSPHONATE, METHYLPHOSPHONIC ACID DIISOPROPYL ESTER, Parathion hydrolase, ... | | 著者 | Hill, C.M, Li, W, Thoden, J.B, Holden, H.M, Raushel, F.M. | | 登録日 | 2003-04-29 | | 公開日 | 2003-09-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Enhanced degradation of chemical warfare agents through molecular engineering of the phosphotriesterase active site.
J.Am.Chem.Soc., 125, 2003
|
|
7TEW
 | | Cryo-EM structure of SARS-CoV-2 Delta (B.1.617.2) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | | 著者 | Zhu, X, Saville, J.W, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Zhou, S, Tuttle, K.S, Subramaniam, S. | | 登録日 | 2022-01-06 | | 公開日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | | 主引用文献 | Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants.
Nat Commun, 13, 2022
|
|
7TEZ
 | | Cryo-EM structure of SARS-CoV-2 Kappa (B.1.617.1) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | | 著者 | Zhu, X, Saville, J.W, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Zhou, S, Tuttle, K.S, Subramaniam, S. | | 登録日 | 2022-01-06 | | 公開日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants.
Nat Commun, 13, 2022
|
|
