2GJJ

Crystal structure of a single chain antibody scA21 against Her2/ErbB2

Summary for 2GJJ

• Entry DOI: 10.2210/pdb2gjj/pdb
• Descriptor: A21 single-chain antibody fragment against erbB2, GLYCEROL (3 entities in total)
• Functional Keywords: ig family, scfv, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 57284.81

Authors

Zhu, Z. (deposition date: 2006-03-31, release date: 2006-10-01, Last modification date: 2023-10-25)

• Primary citation: Hu, S.,Zhu, Z.,Li, L.,Chang, L.,Li, W.,Cheng, L.,Teng, M.,Liu, J.; Epitope mapping and structural analysis of an anti-ErbB2 antibody A21: Molecular basis for tumor inhibitory mechanism; Proteins, 70:938-949, 2007; PubMed: 17847085; DOI: 10.1002/prot.21551

Experimental method

X-RAY DIFFRACTION (2.1 Å)