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6LU6
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BU of 6lu6 by Molmil
Crystal structure of BPTF-BRD with ligand DCBPin5-2 bound
分子名称: 6-[1-[3-(dimethylamino)propyl]indol-5-yl]-2-methylsulfonyl-N-propyl-pyrimidin-4-amine, Nucleosome-remodeling factor subunit BPTF
著者Lu, T, Lu, H.B, Wang, J, Lin, H, Lu, W, Luo, C.
登録日2020-01-26
公開日2021-04-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.970063 Å)
主引用文献Discovery and Optimization of Small-Molecule Inhibitors for the BPTF Bromodomains Proteins
To Be Published
8WDW
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BU of 8wdw by Molmil
Crystal structure of a novel PU plastic degradation urethanase UMG-SP2 from uncultured bacterium
分子名称: GLYCEROL, SULFATE ION, UMG-SP2, ...
著者Cong, L, Li, Z.S, Gao, J, Li, Q, Chen, Y.Y, Han, X, Gert, W, Wei, R, Liu, W.D, Bornscheuer, U.T.
登録日2023-09-16
公開日2024-09-18
最終更新日2025-04-23
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Structure-Guided Engineering of a Versatile Urethanase Improves Its Polyurethane Depolymerization Activity.
Adv Sci, 12, 2025
6IYA
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BU of 6iya by Molmil
Structure of the DNA binding domain of antitoxin CopASO
分子名称: Transcriptional regulator CopG family
著者Zhao, R, Li, F, Liu, L, Zhang, X.
登録日2018-12-14
公開日2019-01-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and allosteric coupling of type II antitoxin CopASO.
Biochem.Biophys.Res.Commun., 514, 2019
7X8G
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BU of 7x8g by Molmil
Crystal structure of ENL T1(H116P) mutant YEATS domain in complex with histone H3 acetylation at K27
分子名称: H3K27ac(24-27) peptide, Protein ENL
著者Li, Y, Peng, B, Li, H.
登録日2022-03-12
公開日2023-01-18
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer.
Mol.Cell, 82, 2022
7X8B
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BU of 7x8b by Molmil
Crystal structure of ENL T1 mutant YEATS domain in complex with histone H3 acetylation at K27
分子名称: H3K27ac(24-27) peptide, Protein ENL
著者Li, Y, Peng, B, Li, H.
登録日2022-03-11
公開日2023-01-18
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer.
Mol.Cell, 82, 2022
7X8F
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BU of 7x8f by Molmil
Crystal structure of ENL T4 mutant YEATS domain in complex with histone H3 acetylation at K27
分子名称: CHLORIDE ION, H3K27ac(24-27) peptide, Protein ENL
著者Li, Y, Peng, B, Li, H.
登録日2022-03-12
公開日2023-01-18
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer.
Mol.Cell, 82, 2022
7X88
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BU of 7x88 by Molmil
Crystal structure of ENL YEATS domain T2 mutant in complex with histone H3 acetylation at K27
分子名称: CITRIC ACID, Histone H3K27ac(24-27) peptide, Protein ENL
著者Li, Y.Y, Li, H.T.
登録日2022-03-11
公開日2023-01-18
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer.
Mol.Cell, 82, 2022
6INH
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BU of 6inh by Molmil
A glycosyltransferase with UDP and the substrate
分子名称: 1-O-[(8alpha,9beta,10alpha,13alpha)-13-(beta-D-glucopyranosyloxy)-18-oxokaur-16-en-18-yl]-beta-D-glucopyranose, GLYCEROL, UDP-glycosyltransferase 76G1, ...
著者Zhu, X.
登録日2018-10-25
公開日2019-07-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations.
Nat Commun, 10, 2019
5H33
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BU of 5h33 by Molmil
Structural basis for dimerization of the death effector domains of Caspase-8
分子名称: Caspase-8
著者Shen, C, Pei, J, Guo, X, Quan, J.
登録日2016-10-20
公開日2017-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.600138 Å)
主引用文献Structural basis for dimerization of the death effector domains of Caspase-8
To Be Published
5GLY
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BU of 5gly by Molmil
Crystal structure of a glycoside hydrolase in complex with cellotetrose from Thielavia terrestris NRRL 8126
分子名称: Glycoside hydrolase family 45 protein, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose
著者Gao, J, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T.
登録日2016-07-12
公開日2017-04-19
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Characterization and crystal structure of a thermostable glycoside hydrolase family 45 1,4-beta-endoglucanase from Thielavia terrestris
Enzyme Microb. Technol., 99, 2017
5GLX
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BU of 5glx by Molmil
Crystal structure of a glycoside hydrolase from Thielavia terrestris NRRL 8126
分子名称: Glycoside hydrolase family 45 protein
著者Gao, J, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T.
登録日2016-07-12
公開日2017-04-19
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Characterization and crystal structure of a thermostable glycoside hydrolase family 45 1,4-beta-endoglucanase from Thielavia terrestris
Enzyme Microb. Technol., 99, 2017
5GM5
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BU of 5gm5 by Molmil
Crystal structure of FI-CMCase from Aspergillus aculeatus F-50 in complex with cellobiose
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endoglucanase-1, SULFATE ION, ...
著者Huang, J.W, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T.
登録日2016-07-12
公開日2017-05-17
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal structure and genetic modifications of FI-CMCase from Aspergillus aculeatus F-50
Biochem. Biophys. Res. Commun., 478, 2016
6INI
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BU of 6ini by Molmil
a glycosyltransferase complex with UDP and the product
分子名称: (8alpha,9beta,10alpha,13alpha)-13-{[beta-D-glucopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->3)]-beta-D-glucopyranosyl]oxy}kaur-16-en-18-oic acid, 1-O-[(8alpha,9beta,10alpha,13alpha)-13-(beta-D-glucopyranosyloxy)-18-oxokaur-16-en-18-yl]-beta-D-glucopyranose, GLYCEROL, ...
著者Zhu, X, Yang, T, Naismith, J.H.
登録日2018-10-25
公開日2019-07-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations.
Nat Commun, 10, 2019
7WIG
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BU of 7wig by Molmil
Cryo-EM structure of the L-054,264-bound human SSTR2-Gi1 complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Chen, L, Wang, W, Dong, Y, Shen, D, Guo, J, Qin, J, Zhang, H, Shen, Q, Zhang, Y, Mao, C.
登録日2022-01-03
公開日2022-06-01
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structures of the endogenous peptide- and selective non-peptide agonist-bound SSTR2 signaling complexes.
Cell Res., 32, 2022
7WIC
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BU of 7wic by Molmil
Cryo-EM structure of the SS-14-bound human SSTR2-Gi1 complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Chen, L, Wang, W, Dong, Y, Shen, D, Guo, J, Qin, J, Zhang, H, Shen, Q, Zhang, Y, Mao, C.
登録日2022-01-03
公開日2022-06-01
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structures of the endogenous peptide- and selective non-peptide agonist-bound SSTR2 signaling complexes.
Cell Res., 32, 2022
6JJS
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BU of 6jjs by Molmil
Crystal structure of an enzyme from Penicillium herquei in condition2
分子名称: ACETATE ION, PhnH
著者Fen, Y, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T.
登録日2019-02-26
公開日2020-01-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Crystal structure and proposed mechanism of an enantioselective hydroalkoxylation enzyme from Penicillium herquei.
Biochem.Biophys.Res.Commun., 516, 2019
6JJT
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BU of 6jjt by Molmil
Crystal structure of an enzyme from Penicillium herquei in condition1
分子名称: CITRIC ACID, DI(HYDROXYETHYL)ETHER, PhnH
著者Fen, Y, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T.
登録日2019-02-26
公開日2020-01-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Crystal structure and proposed mechanism of an enantioselective hydroalkoxylation enzyme from Penicillium herquei.
Biochem.Biophys.Res.Commun., 516, 2019
6ING
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BU of 6ing by Molmil
A complex structure of H25A mutant of glycosyltransferase with UDP
分子名称: GLYCEROL, UDP-glycosyltransferase 76G1, URIDINE-5'-DIPHOSPHATE
著者Zhu, X, Naismith, J.H.
登録日2018-10-25
公開日2019-07-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations.
Nat Commun, 10, 2019
4RSE
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BU of 4rse by Molmil
Crystal structure of RPE65 in complex with MB-001 and palmitate
分子名称: (1R)-3-amino-1-{3-[(2,6,6-trimethylcyclohex-1-en-1-yl)methoxy]phenyl}propan-1-ol, FE (II) ION, PALMITIC ACID, ...
著者Kiser, P.D, Shi, W, Palczewski, K.
登録日2014-11-07
公開日2015-04-15
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Catalytic mechanism of a retinoid isomerase essential for vertebrate vision.
Nat.Chem.Biol., 11, 2015
2YPT
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BU of 2ypt by Molmil
Crystal structure of the human nuclear membrane zinc metalloprotease ZMPSTE24 mutant (E336A) in complex with a synthetic CSIM tetrapeptide from the C-terminus of prelamin A
分子名称: CAAX PRENYL PROTEASE 1 HOMOLOG, PRELAMIN-A/C, ZINC ION
著者Pike, A.C.W, Dong, Y.Y, Quigley, A, Dong, L, Savitsky, P, Cooper, C.D.O, Chaikuad, A, Goubin, S, Shrestha, L, Li, Q, Mukhopadhyay, S, Yang, J, Xia, X, Shintre, C.A, Barr, A.J, Berridge, G, Chalk, R, Bray, J.E, von Delft, F, Bullock, A, Bountra, C, Arrowsmith, C.H, Edwards, A, Burgess-Brown, N, Carpenter, E.P.
登録日2012-11-01
公開日2012-12-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献The Structural Basis of Zmpste24-Dependent Laminopathies.
Science, 339, 2013
4RSC
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BU of 4rsc by Molmil
Crystal structure of RPE65 in complex with emixustat and palmitate
分子名称: (1R)-3-amino-1-[3-(cyclohexylmethoxy)phenyl]propan-1-ol, FE (II) ION, PALMITIC ACID, ...
著者Kiser, P.D, Shi, W, Palczewski, K.
登録日2014-11-07
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Catalytic mechanism of a retinoid isomerase essential for vertebrate vision.
Nat.Chem.Biol., 11, 2015
6INF
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BU of 6inf by Molmil
a glycosyltransferase complex with UDP
分子名称: UDP-glycosyltransferase 76G1, URIDINE-5'-DIPHOSPHATE
著者Zhu, X, Yang, T, Naismith, J.H.
登録日2018-10-25
公開日2019-07-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations.
Nat Commun, 10, 2019
4HLR
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BU of 4hlr by Molmil
Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein
分子名称: Gp41, HEXANE-1,6-DIOL
著者Liu, J, Lu, M.
登録日2012-10-17
公開日2013-10-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein
To be Published
8XGC
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BU of 8xgc by Molmil
Structure of yeast replisome associated with FACT and histone hexamer, Composite map
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ...
著者Li, N, Gao, Y, Yu, D, Gao, N, Zhai, Y.
登録日2023-12-15
公開日2024-02-14
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Parental histone transfer caught at the replication fork.
Nature, 627, 2024
7E74
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BU of 7e74 by Molmil
Crystal structure of ENL YEATS domain T3 mutant in complex with histone H3 acetylation at K27
分子名称: ALA-ALA-ARG-ALY, Protein ENL
著者Li, Y, Li, H.
登録日2021-02-25
公開日2021-07-07
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer.
Mol.Cell, 82, 2022

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件を2025-07-09に公開中

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