6V3O
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6V6G
| Crystal structure of CTX-M-14 E166A/P167S/D240G beta-lactamase | 分子名称: | Beta-lactamase, DI(HYDROXYETHYL)ETHER, SODIUM ION | 著者 | Brown, C.A, Hu, L, Sankaran, B, Prasad, B.V.V, Palzkill, T.G. | 登録日 | 2019-12-05 | 公開日 | 2020-04-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Antagonism between substitutions in beta-lactamase explains a path not taken in the evolution of bacterial drug resistance. J.Biol.Chem., 295, 2020
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6V6P
| Crystal structure of CTX-M-14 E166A/D240G beta-lactamase | 分子名称: | Beta-lactamase, DI(HYDROXYETHYL)ETHER, SULFATE ION | 著者 | Brown, C.A, Hu, L, Sankaran, B, Prasad, B.V.V, Palzkill, T.G. | 登録日 | 2019-12-05 | 公開日 | 2020-04-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Antagonism between substitutions in beta-lactamase explains a path not taken in the evolution of bacterial drug resistance. J.Biol.Chem., 295, 2020
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3MBW
| Crystal structure of the human ephrin A2 LBD and CRD domains in complex with ephrin A1 | 分子名称: | Ephrin type-A receptor 2, Ephrin-A1, UNKNOWN ATOM OR ION, ... | 著者 | Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2010-03-26 | 公開日 | 2010-06-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Architecture of Eph receptor clusters. Proc.Natl.Acad.Sci.USA, 107, 2010
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8VUI
| Structure of FabS1CE-EPR-1, an elbow-locked Fab, in complex with the erythropoeitin receptor | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ... | 著者 | Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sidhu, S.S. | 登録日 | 2024-01-29 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones. Protein Sci., 33, 2024
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6UVK
| OXA-48 bound by inhibitor CDD-97 | 分子名称: | 1,2-ETHANEDIOL, 1-{4-[4-(2-ethoxyphenyl)piperazin-1-yl]-1,3,5-triazin-2-yl}piperidine-4-carboxylic acid, Beta-lactamase, ... | 著者 | Taylor, D.M, Hu, L, Prasad, B.V.V, Sankaran, B, Palzkill, T.G. | 登録日 | 2019-11-02 | 公開日 | 2020-05-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries. Acs Infect Dis., 6, 2020
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6VH7
| Doublet Tau Fibril from Corticobasal Degeneration Human Brain Tissue | 分子名称: | Microtubule-associated protein tau | 著者 | Arakhamia, T, Lee, C.E, Carlomagno, Y, Duong, D.M, Kundinger, S.R, Wang, K, Williams, D, DeTure, M, Dickson, D.W, Cook, C.N, Seyfried, N.T, Petrucelli, L, Fitzpatrick, A.W.P. | 登録日 | 2020-01-09 | 公開日 | 2020-03-04 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains. Cell, 180, 2020
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2ME4
| HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle | 分子名称: | Envelope glycoprotein gp160 | 著者 | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | 登録日 | 2013-09-20 | 公開日 | 2013-10-09 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41. J.Mol.Biol., 426, 2014
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6UPV
| Alpha-E-catenin ABD-F-actin complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Mei, L, Alushin, G.M. | 登録日 | 2019-10-18 | 公開日 | 2020-09-30 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Molecular mechanism for direct actin force-sensing by alpha-catenin. Elife, 9, 2020
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6UVN
| CryoEM structure of VcCascasde-TniQ complex | 分子名称: | Cas6, Cas7, Cas8/5, ... | 著者 | Chang, L, Li, Z, Zhang, H. | 登録日 | 2019-11-03 | 公開日 | 2020-01-29 | 最終更新日 | 2020-02-19 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structure of a type I-F CRISPR RNA guided surveillance complex bound to transposition protein TniQ. Cell Res., 30, 2020
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6ZM8
| Structure of muramidase from Acremonium alcalophilum | 分子名称: | muramidase | 著者 | Moroz, O.V, Blagova, E, Taylor, E, Turkenburg, J.P, Skov, L.K, Gippert, G.P, Schnorr, K.M, Ming, L, Ye, L, Klausen, M, Cohn, M.T, Schmidt, E.G.W, Nymand-Grarup, S, Davies, G.J, Wilson, K.S. | 登録日 | 2020-07-01 | 公開日 | 2021-07-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (0.78 Å) | 主引用文献 | Fungal GH25 muramidases: New family members with applications in animal nutrition and a crystal structure at 0.78 angstrom resolution. Plos One, 16, 2021
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6ZMV
| Structure of muramidase from Trichobolus zukalii | 分子名称: | GLYCEROL, SULFATE ION, muramidase | 著者 | Moroz, O.V, Blagova, E, Taylor, E, Turkenburg, J.P, Skov, L.K, Gippert, G.P, Schnorr, K.M, Ming, L, Ye, L, Klausen, M, Cohn, M.T, Schmidt, E.G.W, Nymand-Grarup, S, Davies, G.J, Wilson, K.S. | 登録日 | 2020-07-04 | 公開日 | 2021-07-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Fungal GH25 muramidases: New family members with applications in animal nutrition and a crystal structure at 0.78 angstrom resolution. Plos One, 16, 2021
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6V69
| Structures of GCP4 and GCP5 in the native human gamma-tubulin ring complex | 分子名称: | Gamma-tubulin complex component 4, Gamma-tubulin complex component 5 | 著者 | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | 登録日 | 2019-12-04 | 公開日 | 2020-01-01 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex. Cell, 180, 2020
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2ME1
| HIV-1 gp41 clade B double alanine mutant Membrane Proximal External Region peptide in DPC micelle | 分子名称: | Gp41 | 著者 | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | 登録日 | 2013-09-20 | 公開日 | 2013-10-09 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41. J.Mol.Biol., 426, 2014
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6URG
| Cryo-EM structure of human CPSF160-WDR33-CPSF30-CPSF100 PIM complex | 分子名称: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor subunit 4, ... | 著者 | Sun, Y, Zhang, Y, Walz, T, Tong, L. | 登録日 | 2019-10-23 | 公開日 | 2019-11-27 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural Insights into the Human Pre-mRNA 3'-End Processing Machinery. Mol.Cell, 77, 2020
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6RVA
| STRUCTURE OF [ASP58]-IGF-I ANALOGUE | 分子名称: | Insulin-like growth factor I | 著者 | Jiracek, J, Zakova, L, Socha, O. | 登録日 | 2019-05-31 | 公開日 | 2019-10-02 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Mutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2 result in receptor- and hormone-specific responses. J.Biol.Chem., 294, 2019
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5BO8
| Structure of human sialyltransferase ST8SiaIII | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ... | 著者 | Volkers, G, Worrall, L, Strynadka, N.C.J. | 登録日 | 2015-05-27 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation. Nat.Struct.Mol.Biol., 22, 2015
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6UYU
| Crystal structure of K45-acetylated SUMO1 in complex with phosphorylated PML-SIM | 分子名称: | Protein PML, Small ubiquitin-related modifier 1 | 著者 | Wahba, H.M, Gagnon, C, Mascle, X.H, Lussier-Price, M, Cappadocia, L, Sakaguchi, K, Omichinski, J.G. | 登録日 | 2019-11-14 | 公開日 | 2019-11-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx in a Protein-Specific Manner. Structure, 28, 2020
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6V36
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6V6C
| Structure of GCP6 in the native human gamma-tubulin ring complex | 分子名称: | Gamma-tubulin complex component 6 | 著者 | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | 登録日 | 2019-12-04 | 公開日 | 2020-01-01 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex. Cell, 180, 2020
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4HJK
| U7Ub7 Disulfide variant | 分子名称: | PHOSPHATE ION, Ubiquitin | 著者 | Murray, J.M, Rouge, L. | 登録日 | 2012-10-12 | 公開日 | 2012-11-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.784 Å) | 主引用文献 | Potent and selective inhibitors of USP7/HAUSP activity by protein conformational stabilization to be published
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4HLE
| Compound 21 (1-alkyl-substituted 1,2,4-triazoles) | 分子名称: | 2-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-4,5-dihydrothieno[3,2-d][1]benzoxepine-8-carboxamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 著者 | Murray, J.M, Rouge, L, Wu, P. | 登録日 | 2012-10-16 | 公開日 | 2013-01-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Cis-Amide isosteric replacement in thienobenzoxepin inhibitors of PI3-kinase. Bioorg.Med.Chem.Lett., 23, 2013
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6UOF
| 1.2 Angstrom Resolution Crystal Structure of CBS Domains of Transcriptional Regulator from Streptococcus pneumoniae | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... | 著者 | Minasov, G, Shuvalova, L, Dubrovska, I, Kiryukhina, O, Endres, M, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-10-14 | 公開日 | 2019-11-06 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | 1.2 Angstrom Resolution Crystal Structure of CBS Domains of Transcriptional Regulator from Streptococcus pneumoniae To Be Published
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3OAD
| Design and optimization of new piperidines as renin inhibitors | 分子名称: | (3S,4R)-N-[2-chloro-5-(2-methoxyethyl)benzyl]-N-cyclopropyl-4-{6-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]pyridin-3-yl}-4-hydroxypiperidine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin | 著者 | Prade, L. | 登録日 | 2010-08-05 | 公開日 | 2010-11-03 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Design and optimization of new piperidines as renin inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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2ME2
| HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle | 分子名称: | Envelope glycoprotein gp160 | 著者 | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | 登録日 | 2013-09-20 | 公開日 | 2013-10-09 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41. J.Mol.Biol., 426, 2014
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