4JM2
 
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4JPI
 | | Crystal structure of a putative VRC01 germline precursor Fab | | 分子名称: | GLYCEROL, Putative VRC01 germline Fab heavy chain, Putative VRC01 germline Fab light chain | | 著者 | Julien, J.-P, Diwanji, D.C, Jardine, J, Schief, W.R, Wilson, I.A. | | 登録日 | 2013-03-19 | | 公開日 | 2013-04-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Rational HIV immunogen design to target specific germline B cell receptors.
Science, 340, 2013
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4K3H
 | | Immunoglobulin lambda variable domain L5(L89S) fluorogen activationg protein in complex with malachite green | | 分子名称: | 4-{bis[4-(dimethylamino)phenyl]methyl}phenol, GLYCEROL, Immunoglobulin lambda variable domain L5(L89S), ... | | 著者 | Stanfield, R.L, Szent-Gyorgyi, C, Wilson, I.A. | | 登録日 | 2013-04-10 | | 公開日 | 2013-10-09 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Malachite Green Mediates Homodimerization of Antibody VL Domains to Form a Fluorescent Ternary Complex with Singular Symmetric Interfaces.
J.Mol.Biol., 425, 2013
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4K3D
 | | Crystal structure of bovine antibody BLV1H12 with ultralong CDR H3 | | 分子名称: | BOVINE ANTIBODY WITH ULTRALONG CDR H3, HEAVY CHAIN, LIGHT CHAIN, ... | | 著者 | Ekiert, D.C, Wang, F, Wilson, I.A. | | 登録日 | 2013-04-10 | | 公開日 | 2013-06-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Reshaping antibody diversity.
Cell(Cambridge,Mass.), 153, 2013
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4K3E
 | | Crystal structure of bovine antibody BLV5B8 with ultralong CDR H3 | | 分子名称: | BOVINE ANTIBODY WITH ULTRALONG CDR H3, HEAVY CHAIN, LIGHT CHAIN, ... | | 著者 | Ekiert, D.C, Wang, F, Wilson, I.A. | | 登録日 | 2013-04-10 | | 公開日 | 2013-06-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Reshaping antibody diversity.
Cell(Cambridge,Mass.), 153, 2013
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4K3X
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4JPK
 | | Crystal structure of the germline-targeting HIV-1 gp120 engineered outer domain eOD-GT6 in complex with a putative VRC01 germline precursor Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6, ... | | 著者 | Julien, J.-P, Jardine, J, Schief, W.R, Wilson, I.A. | | 登録日 | 2013-03-19 | | 公開日 | 2013-04-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Rational HIV immunogen design to target specific germline B cell receptors.
Science, 340, 2013
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3CFJ
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4JY6
 | | Crystal structure of human Fab PGT123, a broadly reactive and potent HIV-1 neutralizing antibody | | 分子名称: | GLYCEROL, PGT123 heavy chain, PGT123 light chain, ... | | 著者 | Julien, J.-P, Diwanji, D.C, Burton, D.R, Wilson, I.A. | | 登録日 | 2013-03-29 | | 公開日 | 2013-05-08 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans.
Plos Pathog., 9, 2013
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3CFD
 | | Purple-fluorescent antibody EP2-25C10 in complex with its stilbene hapten | | 分子名称: | 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID, GLYCEROL, PURPLE-FLUORESCENT ANTIBODY EP2-25C10-IGG2B HEAVY CHAIN, ... | | 著者 | Debler, E.W, Heine, A, Wilson, I.A. | | 登録日 | 2008-03-03 | | 公開日 | 2008-03-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
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3CFC
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3CN0
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4JY5
 | | Crystal structure of human Fab PGT122, a broadly reactive and potent HIV-1 neutralizing antibody | | 分子名称: | GLYCEROL, PGT122 heavy chain, PGT122 light chain | | 著者 | Julien, J.-P, Diwanji, D.C, Burton, D.R, Wilson, I.A. | | 登録日 | 2013-03-29 | | 公開日 | 2013-05-08 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.
Plos Pathog., 9, 2013
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3E6J
 | | Crystal Structure of Variable Lymphocyte Receptor (VLR) RBC36 in Complex with H-trisaccharide | | 分子名称: | GLYCEROL, SULFATE ION, Variable lymphocyte receptor diversity region, ... | | 著者 | Han, B.W, Herrin, B.R, Cooper, M.D, Wilson, I.A. | | 登録日 | 2008-08-15 | | 公開日 | 2008-10-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Antigen recognition by variable lymphocyte receptors.
Science, 321, 2008
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4JM4
 | | Crystal Structure of PGT 135 Fab | | 分子名称: | PGT 135 Heavy Chain, PGT 135 Light Chain | | 著者 | Kong, L, Wilson, I.A. | | 登録日 | 2013-03-13 | | 公開日 | 2013-05-29 | | 最終更新日 | 2013-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.751 Å) | | 主引用文献 | Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120.
Nat.Struct.Mol.Biol., 20, 2013
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4JPJ
 | | Crystal structure of the germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6 | | 著者 | Julien, J.-P, Jardine, J, Schief, W.R, Wilson, I.A. | | 登録日 | 2013-03-19 | | 公開日 | 2013-04-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Rational HIV immunogen design to target specific germline B cell receptors.
Science, 340, 2013
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4L1T
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3ESP
 | | Human transthyretin (TTR) complexed with N-(3,5-Dibromo-4-hydroxyphenyl)-3,5-dimethyl-4-hydroxybenzamide | | 分子名称: | N-(3,5-dibromo-4-hydroxyphenyl)-4-hydroxy-3,5-dimethylbenzamide, Transthyretin | | 著者 | Connelly, S, Wilson, I.A. | | 登録日 | 2008-10-06 | | 公開日 | 2009-04-07 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | | 主引用文献 | Toward optimization of the second aryl substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.
J.Med.Chem., 52, 2009
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4K3G
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3CN3
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4K3Y
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3CN1
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4KY2
 | | Transthyretin in complex with the fluorescent folding sensor (E)-7-hydroxy-3-(4-hydroxy-3,5-dimethylstyryl)-4-methyl-2H-chromen-2-one | | 分子名称: | 7-hydroxy-3-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]-4-methyl-2H-chromen-2-one, Transthyretin | | 著者 | Connelly, S, Wilson, I.A, Choi, S. | | 登録日 | 2013-05-28 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | | 主引用文献 | Bifunctional coumarin derivatives that inhibit transthyretin amyloidogenesis and serve as fluorescent transthyretin folding sensors.
Chem.Commun.(Camb.), 49, 2013
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4L1S
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3CFE
 | | Crystal structure of purple-fluorescent antibody EP2-25C10 | | 分子名称: | GLYCEROL, PURPLE-FLUORESCENT ANTIBODY EP2-25C10-IGG2B HEAVY CHAIN, PURPLE-FLUORESCENT ANTIBODY EP2-25C10-KAPPA LIGHT CHAIN, ... | | 著者 | Debler, E.W, Heine, A, Wilson, I.A. | | 登録日 | 2008-03-03 | | 公開日 | 2008-03-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
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