Search by PDB author

The Jak1 kinase domain in complex with inhibitor
分子名称:	1,2-ETHANEDIOL, 2-methyl-1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine, Tyrosine-protein kinase JAK1
著者	Lupardus, P.J, Steffek, M.
登録日	2012-04-04
公開日	2012-07-04
最終更新日	2013-01-23
実験手法	X-RAY DIFFRACTION (2.174 Å)
主引用文献	Discovery and optimization of C-2 methyl imidazopyrrolopyridines as potent and orally bioavailable JAK1 inhibitors with selectivity over JAK2. J.Med.Chem., 55, 2012

4EI4

JAK1 kinase (JH1 domain) in complex with compound 20
分子名称:	(1R,3R)-3-(2-methylimidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(8H)-yl)cyclohexanol, Tyrosine-protein kinase JAK1
著者	Eigenbrot, C, Steffek, M.
登録日	2012-04-04
公開日	2012-07-04
最終更新日	2023-12-06
実験手法	X-RAY DIFFRACTION (2.22 Å)
主引用文献	Discovery and optimization of C-2 methyl imidazopyrrolopyridines as potent and orally bioavailable JAK1 inhibitors with selectivity over JAK2. J.Med.Chem., 55, 2012

4F08

Discovery and Optimization of C-2 Methyl Imidazo-pyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2
分子名称:	1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine, Tyrosine-protein kinase JAK2
著者	Murray, J.M.
登録日	2012-05-03
公開日	2012-07-04
最終更新日	2023-12-06
実験手法	X-RAY DIFFRACTION (2.82 Å)
主引用文献	Discovery and Optimization of C-2 Methyl Imidazopyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2. J.Med.Chem., 55, 2012

4F09

Discovery and Optimization of C-2 Methyl Imidazo-pyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2
分子名称:	2-methyl-1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine, Tyrosine-protein kinase JAK2
著者	Murray, J.M.
登録日	2012-05-03
公開日	2012-07-04
最終更新日	2023-12-06
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Discovery and Optimization of C-2 Methyl Imidazopyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2. J.Med.Chem., 55, 2012

5Z9R

NMNAT as a specific chaperone antagonizing pathological condensation of phosphorylated tau
分子名称:	Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3
著者	Dou, S, Ma, X, Li, D, Liu, C.
登録日	2018-02-05
公開日	2019-02-06
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Nicotinamide mononucleotide adenylyltransferase uses its NAD+substrate-binding site to chaperone phosphorylated Tau. Elife, 9, 2020

6CB7

CRYSTAL STRUCTURE OF VACCINIA VIRUS A6 N-TERMINUS (SPACE GROUP C2)
分子名称:	NICKEL (II) ION, Protein A6
著者	Han, Y, Zhang, B, Deng, J.
登録日	2018-02-02
公開日	2018-12-12
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Structure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

6CB6

CRYSTAL STRUCTURE OF VACCINIA VIRUS A6 N-TERMINUS (SPACE GROUP C2)
分子名称:	Protein A6
著者	Han, Y, Zhang, B, Deng, J.
登録日	2018-02-02
公開日	2018-12-12
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Structure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

4QAU

Crystal structure of F43Y mutant of sperm whale myoglobin
分子名称:	Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
著者	Lin, Y, Tan, X, Li, W.
登録日	2014-05-06
公開日	2015-01-21
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (1.597 Å)
主引用文献	A Novel Tyrosine-Heme C-O Covalent Linkage in F43Y Myoglobin: A New Post-translational Modification of Heme Proteins Chembiochem, 16, 2015

6DJA

ZN-DEPENDENT 5/B/6 METALLO-BETA-LACTAMASE FROM BACILLUS CEREUS
分子名称:	Metallo-beta-lactamase type 2, ZINC ION
著者	Bui, A.A, Khan, N.H, Shaw, R.W, Sutton, R.B.
登録日	2018-05-24
公開日	2019-05-29
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.48 Å)
主引用文献	A DNA aptamer reveals an allosteric site for inhibition in metallo-beta-lactamases. Plos One, 14, 2019

8I0C

Crystal structure of Aldo-keto reductase 1C3 complexed with compound S0703
分子名称:	1-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]cyclopropane-1-carboxylic acid, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者	Jiang, J, He, S, Liu, Y, Fang, P, Sun, H.
登録日	2023-01-10
公開日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.33 Å)
主引用文献	Development of Biaryl-Containing Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors for Reversing AKR1C3-Mediated Drug Resistance in Cancer Treatment. J.Med.Chem., 66, 2023

7Y1A

Lateral hexamer
分子名称:	B-phycoerythrin beta chain, LRH, PHYCOERYTHROBILIN, ...
著者	You, X, Zhang, X, Cheng, J, Xiao, Y.N, Sun, S, Sui, S.F.
登録日	2022-06-07
公開日	2023-01-18
最終更新日	2023-04-19
実験手法	ELECTRON MICROSCOPY (6.3 Å)
主引用文献	In situ structure of the red algal phycobilisome-PSII-PSI-LHC megacomplex. Nature, 616, 2023

7Y4L

PBS of PBS-PSII-PSI-LHCs from Porphyridium purpureum.
分子名称:	Allophycocyanin alpha subunit, Allophycocyanin beta 18 subunit, Allophycocyanin beta subunit, ...
著者	You, X, Zhang, X, Cheng, J, Xiao, Y.N, Sun, S, Sui, S.F.
登録日	2022-06-15
公開日	2023-01-18
最終更新日	2023-04-19
実験手法	ELECTRON MICROSCOPY (3.3 Å)
主引用文献	In situ structure of the red algal phycobilisome-PSII-PSI-LHC megacomplex. Nature, 616, 2023

4O0Y

Back pocket flexibility provides group-II PAK selectivity for type 1 kinase inhibitors
分子名称:	4-[1-(4-amino-1,3,5-triazin-2-yl)-2-(ethylamino)-1H-benzimidazol-6-yl]-2-methylbut-3-yn-2-ol, Serine/threonine-protein kinase PAK 4
著者	Rouge, L, Tam, C, Wang, W.
登録日	2013-12-14
公開日	2014-02-12
最終更新日	2014-02-26
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors. J.Med.Chem., 57, 2014

4O0T

Back pocket flexibility provides group-II PAK selectivity for type 1 kinase inhibitors
分子名称:	1-({1-(2-aminopyrimidin-4-yl)-2-[(2-methoxyethyl)amino]-1H-benzimidazol-6-yl}ethynyl)cyclohexanol, Serine/threonine-protein kinase PAK 1
著者	Oh, A, Tam, C, Wang, W.
登録日	2013-12-14
公開日	2014-02-12
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors. J.Med.Chem., 57, 2014

2MTE

Solution structure of Doc48S
分子名称:	CALCIUM ION, Cellulose 1,4-beta-cellobiosidase (reducing end) CelS
著者	Chen, C, Feng, Y.
登録日	2014-08-18
公開日	2014-10-15
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Revisiting the NMR solution structure of the Cel48S type-I dockerin module from Clostridium thermocellum reveals a cohesin-primed conformation. J.Struct.Biol., 188, 2014

4O0R

Back pocket flexibility provides group-II PAK selectivity for type 1 kinase inhibitors
分子名称:	PF-3758309, Serine/threonine-protein kinase PAK 1
著者	Rouge, L, Tam, C, Wang, W.
登録日	2013-12-14
公開日	2014-02-12
最終更新日	2019-01-30
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors. J.Med.Chem., 57, 2014

8HNC

Cryo-EM structure of human OATP1B1 in complex with bilirubin
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(Z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, ...
著者	Shan, Z, Yang, X, Liu, H, Nan, J, Yuan, Y, Zhang, Y.
登録日	2022-12-07
公開日	2023-09-13
最終更新日	2023-12-20
実験手法	ELECTRON MICROSCOPY (3.73 Å)
主引用文献	Cryo-EM structures of human organic anion transporting polypeptide OATP1B1. Cell Res., 33, 2023

8HND

Cryo-EM structure of human OATP1B1 in complex with estrone-3-sulfate
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier organic anion transporter family member 1B1, ...
著者	Shan, Z, Yang, X, Liu, H, Nan, J, Yuan, Y, Zhang, Y.
登録日	2022-12-07
公開日	2023-09-13
最終更新日	2023-12-20
実験手法	ELECTRON MICROSCOPY (3.19 Å)
主引用文献	Cryo-EM structures of human organic anion transporting polypeptide OATP1B1. Cell Res., 33, 2023

4O0V

Back pocket flexibility provides group-II PAK selectivity for type 1 kinase inhibitors
分子名称:	1-({1-(2-aminopyrimidin-4-yl)-2-[(2-methoxyethyl)amino]-1H-benzimidazol-6-yl}ethynyl)cyclohexanol, Serine/threonine-protein kinase PAK 4
著者	Rouge, L, Tam, C, Wang, W.
登録日	2013-12-14
公開日	2014-02-12
最終更新日	2014-02-26
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors. J.Med.Chem., 57, 2014

4O0X

Back pocket flexibility provides group-II PAK selectivity for type 1 kinase inhibitors
分子名称:	1-{[1-(4-amino-1,3,5-triazin-2-yl)-2-methyl-1H-benzimidazol-6-yl]ethynyl}cyclohexanol, Serine/threonine-protein kinase PAK 4
著者	Rouge, L, Tam, C, Wang, W.
登録日	2013-12-14
公開日	2014-02-12
最終更新日	2014-11-05
実験手法	X-RAY DIFFRACTION (2.483 Å)
主引用文献	Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors. J.Med.Chem., 57, 2014

7Y7A

In situ double-PBS-PSII-PSI-LHCs megacomplex from Porphyridium purpureum.
分子名称:	(1R,2S)-4-{(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl}-2,5,5-trimethylcyclohex-3-en-1-ol, (2S)-2,3-dihydroxypropyl octadecanoate, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ...
著者	You, X, Zhang, X, Cheng, J, Xiao, Y.N, Sun, S, Sui, S.F.
登録日	2022-06-22
公開日	2023-02-08
最終更新日	2024-07-03
実験手法	ELECTRON MICROSCOPY (4.3 Å)
主引用文献	In situ structure of the red algal phycobilisome-PSII-PSI-LHC megacomplex. Nature, 616, 2023

7Y5E

In situ single-PBS-PSII-PSI-LHCs megacomplex.
分子名称:	(1R,2S)-4-{(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl}-2,5,5-trimethylcyclohex-3-en-1-ol, (2S)-2,3-dihydroxypropyl octadecanoate, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ...
著者	You, X, Zhang, X, Cheng, J, Xiao, Y.N, Sui, S.F.
登録日	2022-06-17
公開日	2023-02-01
最終更新日	2024-07-03
実験手法	ELECTRON MICROSCOPY (3.3 Å)
主引用文献	In situ structure of the red algal phycobilisome-PSII-PSI-LHC megacomplex. Nature, 616, 2023

6BR9

Structure of A6 reveals a novel lipid transporter
分子名称:	(1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, Protein A6 homolog, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate
著者	Deng, J, Peng, S, Pathak, P.
登録日	2017-11-30
公開日	2018-06-20
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

6BR8

Structure of A6 reveals a novel lipid transporter
分子名称:	(1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, Protein A6 homolog, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate
著者	Deng, J, Peng, S, Pathak, P.
登録日	2017-11-30
公開日	2018-06-20
最終更新日	2019-12-11
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Structure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

8HTX

Crystal structure of BANP in complex with methylated DNA
分子名称:	DNA (5'-D(CPTPCPTP(5CM)PGPCPGPAPGPAPG)-3'), Protein BANP
著者	Zhang, J, Min, J, Liu, K.
登録日	2022-12-21
公開日	2023-05-24
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Structural insights into DNA recognition by the BEN domain of the transcription factor BANP. J.Biol.Chem., 299, 2023

<14 15 16 17 18 19 202122 23 24 25 26 27 28 29 >

全ヒット件数:	710
表示件数:	25
表示順	関連性が高い順