3I68
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3I65
| Plasmodium falciparum dihydroorotate dehydrogenase bound with triazolopyrimidine-based inhibitor DSM1 | 分子名称: | 5-methyl-7-(naphthalen-2-ylamino)-1H-[1,2,4]triazolo[1,5-a]pyrimidine-3,8-diium, Dihydroorotate dehydrogenase homolog, mitochondrial, ... | 著者 | Deng, X, Phillips, M.A. | 登録日 | 2009-07-06 | 公開日 | 2009-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds. J.Biol.Chem., 284, 2009
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3Q3V
| Crystal structure of Phosphoglycerate Kinase from Campylobacter jejuni. | 分子名称: | FORMIC ACID, POTASSIUM ION, Phosphoglycerate kinase, ... | 著者 | Filippova, E.V, Wawrzak, Z, Onopriyenko, O, Edwards, A, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-12-22 | 公開日 | 2011-01-12 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.145 Å) | 主引用文献 | Crystal structures of putative phosphoglycerate kinases from B. anthracis and C. jejuni. J.Struct.Funct.Genom., 13, 2012
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2SNV
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2SNW
| SINDBIS VIRUS CAPSID PROTEIN, TYPE3 CRYSTAL FORM | 分子名称: | COAT PROTEIN C | 著者 | Choi, H.-K, Lee, S, Zhang, Y.-P, Mckinney, B.R, Wengler, G, Rossmann, M.G, Kuhn, R.J. | 登録日 | 1998-02-17 | 公開日 | 1998-04-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. J.Mol.Biol., 262, 1996
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4JRH
| Crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Vibrio Cholerae (space group P43) at 2.2 Angstrom | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 2, ACETATE ION | 著者 | Hou, J, Chruszcz, M, Shabalin, I.G, Zheng, H, Cooper, D.R, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2013-03-21 | 公開日 | 2013-04-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 |
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3QUS
| Crystal Structure of N10-Formyltetrahydrofolate Synthetase with ATPgS | 分子名称: | 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, Formate--tetrahydrofolate ligase, MALEIC ACID, ... | 著者 | Celeste, L.R, Chai, G, Bielak, M, Lovelace, L.L, Lebioda, L. | 登録日 | 2011-02-24 | 公開日 | 2011-12-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Crystal Strucutre of N10-Formyltetrahydrofolate Synthetase with ATPgS To be Published
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5TBO
| Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM421 | 分子名称: | 2-(1,1-difluoroethyl)-5-methyl-N-[6-(trifluoromethyl)pyridin-3-yl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | 著者 | Deng, X, Phillips, M. | 登録日 | 2016-09-12 | 公開日 | 2016-09-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.151 Å) | 主引用文献 | A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria. ACS Infect Dis, 2, 2016
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7SBG
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7SD2
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5FI8
| Crystal structure of plasmodium falciparum dihydroorotate dehydrogenase bounded with DSM422 (Tetrahydro-2-naphthyl and 2-indanyl triazolopyrimidine) | 分子名称: | 2-[1,1-bis(fluoranyl)ethyl]-~{N}-[(2~{S})-7-bromanyl-1,2,3,4-tetrahydronaphthalen-2-yl]-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | 著者 | Deng, X, Kokkonda, S, Tomchick, D, Phillips, M. | 登録日 | 2015-12-22 | 公開日 | 2016-05-18 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial Activity. J.Med.Chem., 59, 2016
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4ORM
| Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM338 (N-[3,5-difluoro-4-(trifluoromethyl)phenyl]-5-methyl-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine) | 分子名称: | Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ... | 著者 | Deng, X, Phillips, M.A. | 登録日 | 2014-02-11 | 公開日 | 2014-06-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Fluorine Modulates Species Selectivity in the Triazolopyrimidine Class of Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors. J.Med.Chem., 57, 2014
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2ID3
| Crystal structure of transcriptional regulator SCO5951 from Streptomyces coelicolor A3(2) | 分子名称: | CALCIUM ION, CHLORIDE ION, Putative transcriptional regulator | 著者 | Grabowski, M, Chruszcz, M, Koclega, K.D, Cymborowski, M, Gu, J, Xu, X, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2006-09-14 | 公開日 | 2006-10-17 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 |
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1WYK
| SINDBIS VIRUS CAPSID PROTEIN (114-264) | 分子名称: | 1,4-DIETHYLENE DIOXIDE, FORMYL GROUP, SINDBIS VIRUS CAPSID PROTEIN | 著者 | Lee, S, Kuhn, R.J, Rossmann, M.G. | 登録日 | 1998-01-12 | 公開日 | 1998-04-29 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Probing the potential glycoprotein binding site of sindbis virus capsid protein with dioxane and model building. Proteins, 33, 1998
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1SVP
| SINDBIS VIRUS CAPSID PROTEIN | 分子名称: | SINDBIS VIRUS CAPSID PROTEIN | 著者 | Lee, S, Rossmann, M.G. | 登録日 | 1996-03-22 | 公開日 | 1996-08-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Identification of a protein binding site on the surface of the alphavirus nucleocapsid and its implication in virus assembly. Structure, 4, 1996
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6CNY
| 2.3 Angstrom Structure of Phosphodiesterase treated Vivid (complex with FMN) | 分子名称: | FLAVIN MONONUCLEOTIDE, Vivid PAS protein VVD | 著者 | Zoltowski, B.D, Shabalin, I.G, Kowiel, M, Porebski, P.J, Crane, B.R, Bilwes, A.M. | 登録日 | 2018-03-09 | 公開日 | 2018-03-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Conformational switching in the fungal light sensor Vivid. Science, 316, 2007
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6CIG
| CRYSTAL STRUCTURE ANALYSIS OF SELENOMETHIONINE SUBSTITUTED ISOFLAVONE O-METHYLTRANSFERASE | 分子名称: | GLYCEROL, Isoflavone-7-O-methyltransferase 8, N-(TRIS(HYDROXYMETHYL)METHYL)-3-AMINOPROPANESULFONIC ACID, ... | 著者 | Zubieta, C, Dixon, R.A, Shabalin, I.G, Kowiel, M, Porebski, P.J, Noel, J.P. | 登録日 | 2018-02-23 | 公開日 | 2018-03-07 | 最終更新日 | 2022-03-23 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structures of two natural product methyltransferases reveal the basis for substrate specificity in plant O-methyltransferases. Nat. Struct. Biol., 8, 2001
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1VCP
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4OQV
| High resolution crystal structure of human dihydroorotate dehydrogenase bound with DSM338 (N-[3,5-difluoro-4-(trifluoromethyl)phenyl]-5-methyl-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine) | 分子名称: | ACETIC ACID, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | 著者 | Deng, X, Phillips, M.A. | 登録日 | 2014-02-10 | 公開日 | 2014-06-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | 主引用文献 | Fluorine Modulates Species Selectivity in the Triazolopyrimidine Class of Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors. J.Med.Chem., 57, 2014
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6COA
| 1.2 A Structure of Thaumatin Crystallized in Gel | 分子名称: | L(+)-TARTARIC ACID, Thaumatin-1 | 著者 | Sauter, C, Lorber, B, Shabalin, I.G, Porebski, P.J, Brzezinski, D, Giege, R. | 登録日 | 2018-03-12 | 公開日 | 2018-03-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Towards atomic resolution with crystals grown in gel: the case of thaumatin seen at room temperature. Proteins, 48, 2002
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4ORI
| Rat dihydroorotate dehydrogenase bound with DSM338 (N-[3,5-difluoro-4-(trifluoromethyl)phenyl]-5-methyl-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine) | 分子名称: | Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ... | 著者 | Deng, X, Phillips, M.A. | 登録日 | 2014-02-11 | 公開日 | 2014-06-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Fluorine Modulates Species Selectivity in the Triazolopyrimidine Class of Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors. J.Med.Chem., 57, 2014
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1CC0
| CRYSTAL STRUCTURE OF THE RHOA.GDP-RHOGDI COMPLEX | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, rho GDP dissociation inhibitor alpha, ... | 著者 | Longenecker, K.L, Read, P, Derewenda, U, Dauter, Z, Garrard, S, Walker, L, Somlyo, A.V, Somlyo, A.P, Nakamoto, R.K, Derewenda, Z.S. | 登録日 | 1999-03-03 | 公開日 | 2000-01-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (5 Å) | 主引用文献 | How RhoGDI binds Rho. Acta Crystallogr.,Sect.D, 55, 1999
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1YQC
| Crystal Structure of Ureidoglycolate Hydrolase (AllA) from Escherichia coli O157:H7 | 分子名称: | GLYOXYLIC ACID, Ureidoglycolate hydrolase | 著者 | Raymond, S, Tocilj, A, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | 登録日 | 2005-02-01 | 公開日 | 2005-10-18 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.709 Å) | 主引用文献 | Crystal structure of ureidoglycolate hydrolase (AllA) from Escherichia coli O157:H7 Proteins, 61, 2005
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3TZH
| Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG)(F187A) from Vibrio cholerae | 分子名称: | 3-oxoacyl-[acyl-carrier protein] reductase, GLYCEROL, SULFATE ION, ... | 著者 | Hou, J, Chruszcz, M, Zheng, H, Cooper, D.R, Osinski, T, Shumilin, I, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2011-09-27 | 公開日 | 2011-10-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 |
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1JFR
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