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5H21
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BU of 5h21 by Molmil
Trimethoxy-ring inhibitor in complex with the first bromodomain of BRD4
分子名称: 3,4,5-trimethoxy-~{N}-(2-thiophen-2-ylethyl)benzamide, Bromodomain-containing protein 4
著者Zhang, H, Luo, C.
登録日2016-10-13
公開日2017-07-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.591 Å)
主引用文献Discovery of novel trimethoxy-ring BRD4 bromodomain inhibitors: AlphaScreen assay, crystallography and cell-based assay.
Medchemcomm, 8, 2017
1BMV
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BU of 1bmv by Molmil
PROTEIN-RNA INTERACTIONS IN AN ICOSAHEDRAL VIRUS AT 3.0 ANGSTROMS RESOLUTION
分子名称: PROTEIN (ICOSAHEDRAL VIRUS - A DOMAIN), PROTEIN (ICOSAHEDRAL VIRUS - B AND C DOMAIN), RNA (5'-R(*GP*GP*UP*CP*AP*AP*AP*AP*UP*GP*C)-3')
著者Chen, Z, Stauffacher, C, Li, Y, Schmidt, T, Bomu, W, Kamer, G, Shanks, M, Lomonossoff, G, Johnson, J.E.
登録日1989-10-09
公開日1989-10-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Protein-RNA interactions in an icosahedral virus at 3.0 A resolution.
Science, 245, 1989
3NBJ
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BU of 3nbj by Molmil
Crystal Structure of Y305F mutant of the copper amine oxidase from Hansenula polymorpha expressed in yeast
分子名称: COPPER (II) ION, PHOSPHATE ION, Peroxisomal primary amine oxidase
著者Chen, Z, Datta, S, DuBois, J.L, Klinman, J.P, Mathews, F.S.
登録日2010-06-03
公開日2010-08-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mutation at a strictly conserved, active site tyrosine in the copper amine oxidase leads to uncontrolled oxygenase activity.
Biochemistry, 49, 2010
3N9H
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BU of 3n9h by Molmil
Crystal Structural of mutant Y305A in the copper amine oxidase from hansenula polymorpha
分子名称: COPPER (II) ION, Peroxisomal primary amine oxidase
著者Chen, Z, Datta, S, DuBois, J.L, Klinman, J.P, Mathews, F.S.
登録日2010-05-30
公開日2010-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mutation at a strictly conserved, active site tyrosine in the copper amine oxidase leads to uncontrolled oxygenase activity.
Biochemistry, 49, 2010
3NBB
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BU of 3nbb by Molmil
Crystal structure of mutant Y305F expressed in E. coli in the copper amine oxidase from hansenula polymorpha
分子名称: COPPER (II) ION, Peroxisomal primary amine oxidase
著者Chen, Z, Datta, S, DuBois, J.L, Klinman, J.P, Mathews, F.S.
登録日2010-06-03
公開日2010-08-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Mutation at a strictly conserved, active site tyrosine in the copper amine oxidase leads to uncontrolled oxygenase activity.
Biochemistry, 49, 2010
6WI5
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BU of 6wi5 by Molmil
De novo designed protein Foldit4
分子名称: De novo designed protein Foldit4
著者Bera, A.K, Koepnick, B, Boykov, A, Baker, D.
登録日2020-04-08
公開日2020-04-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献De novo design of protein logic gates.
Science, 368, 2020
3DR9
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BU of 3dr9 by Molmil
Increased Distal Histidine Conformational Flexibility in the Deoxy Form of Dehaloperoxidase from Amphitrite ornata
分子名称: Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Chen, X, de Serrano, V.S, Betts, L, Franzen, S.
登録日2008-07-10
公開日2009-01-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Distal histidine conformational flexibility in dehaloperoxidase from Amphitrite ornata.
Acta Crystallogr.,Sect.D, 65, 2009
6L5M
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BU of 6l5m by Molmil
Crystal structure of human DEAD-box RNA helicase DDX21 in complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, Nucleolar RNA helicase 2
著者Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X.
登録日2019-10-24
公開日2020-06-17
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Adv Sci, 7, 2020
6K9M
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BU of 6k9m by Molmil
Human LXR-beta in complex with an agonist
分子名称: Oxysterols receptor LXR-beta, ~{tert}-butyl (2'~{S},3~{S})-2-oxidanylidene-2'-propan-2-yl-spiro[1~{H}-indole-3,3'-pyrrolidine]-1'-carboxylate
著者Zhang, Z, Zhou, H.
登録日2019-06-16
公開日2020-06-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Discovery of novel liver X receptor inverse agonists as lipogenesis inhibitors.
Eur.J.Med.Chem., 206, 2020
3CMW
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BU of 3cmw by Molmil
Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DT)-3'), MAGNESIUM ION, ...
著者Pavletich, N.P.
登録日2008-03-24
公開日2008-05-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures.
Nature, 453, 2008
3CMX
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BU of 3cmx by Molmil
Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DA)-3'), DNA (5'-D(*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DT)-3'), ...
著者Pavletich, N.P.
登録日2008-03-24
公開日2008-05-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures.
Nature, 453, 2008
3CMV
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BU of 3cmv by Molmil
Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Protein recA
著者Pavletich, N.P.
登録日2008-03-24
公開日2008-05-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures.
Nature, 453, 2008
3CMU
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BU of 3cmu by Molmil
Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DT)-3'), MAGNESIUM ION, ...
著者Pavletich, N.P.
登録日2008-03-24
公開日2008-05-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures.
Nature, 453, 2008
7U9O
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BU of 7u9o by Molmil
SARS-CoV-2 spike trimer RBD in complex with Fab NE12
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NE12 Fab heavy chain, NE12 Fab light chain, ...
著者Tsybovsky, Y, Kwong, P.D, Farci, P.
登録日2022-03-11
公開日2022-11-23
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants.
Cell Rep, 41, 2022
7U9P
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BU of 7u9p by Molmil
SARS-CoV-2 spike trimer RBD in complex with Fab NA8
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NA8 Fab heavy chain, NA8 Fab light chain, ...
著者Tsybovsky, Y, Kwong, P.D, Farci, P.
登録日2022-03-11
公開日2022-11-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants.
Cell Rep, 41, 2022
6JZE
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BU of 6jze by Molmil
Crystal structure of VASH2-SVBP complex with the magic triangle I3C
分子名称: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 2
著者Chen, Z, Ling, Y, Zeyuan, G, Zhu, L.
登録日2019-05-01
公開日2019-08-07
最終更新日2023-04-05
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer.
Nat Commun, 10, 2019
6JZD
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BU of 6jzd by Molmil
Crystal structure of peptide-bound VASH2-SVBP complex
分子名称: GLU-GLY-GLU-GLU-TYR, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 2
著者Chen, Z, Ling, Y, Zeyuan, G, Zhu, L.
登録日2019-05-01
公開日2019-07-17
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.479 Å)
主引用文献Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer.
Nat Commun, 10, 2019
6JZC
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BU of 6jzc by Molmil
Structural basis of tubulin detyrosination
分子名称: GLYCEROL, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 2
著者Chen, Z, Ling, Y, Zeyuan, G, Zhu, L.
登録日2019-05-01
公開日2019-07-17
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer.
Nat Commun, 10, 2019
4QXH
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BU of 4qxh by Molmil
Crystal structure of histone demethylase KDM2A-H3K36ME1 with NOG
分子名称: Histone H3.2, Lysine-specific demethylase 2A, N-OXALYLGLYCINE, ...
著者Cheng, Z.J, Patel, D.J.
登録日2014-07-20
公開日2014-11-05
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QX7
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BU of 4qx7 by Molmil
Crystal structure of histone demethylase kdm2a-h3k36me2 with alpha-kg
分子名称: 2-OXOGLUTARIC ACID, Histone H3.2, Lysine-specific demethylase 2A, ...
著者Cheng, Z.J, Patel, D.J.
登録日2014-07-18
公開日2014-11-05
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
7CHJ
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BU of 7chj by Molmil
crystal structure of pco4
分子名称: CITRIC ACID, FE (III) ION, Plant cysteine oxidase 4
著者Guo, Q, Xu, C, Liao, S.
登録日2020-07-05
公開日2020-11-25
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana.
J.Struct.Biol., 213, 2021
7CHI
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BU of 7chi by Molmil
crystal structure of pco5
分子名称: FE (III) ION, Plant cysteine oxidase 5
著者Guo, Q, Xu, C, Liao, S.
登録日2020-07-05
公開日2020-11-25
最終更新日2021-03-31
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana.
J.Struct.Biol., 213, 2021
4QXC
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BU of 4qxc by Molmil
Crystal structure of histone demethylase KDM2A-H3K36ME2 with NOG
分子名称: Histone H3.2, Lysine-specific demethylase 2A, N-OXALYLGLYCINE, ...
著者Cheng, Z.J, Patel, D.J.
登録日2014-07-19
公開日2014-11-05
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QXB
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BU of 4qxb by Molmil
crystal structure of histone demethylase KDM2A-H3K36ME3 with NOG
分子名称: Histone H3.2, Lysine-specific demethylase 2A, N-OXALYLGLYCINE, ...
著者Cheng, Z.J, Patel, D.J.
登録日2014-07-19
公開日2014-11-05
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QWN
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BU of 4qwn by Molmil
Histone demethylase KDM2A-H3K36ME1-alpha-KG complex structure
分子名称: 2-OXOGLUTARIC ACID, Histone H3.2, Lysine-specific demethylase 2A, ...
著者Cheng, Z.J, Patel, D.J.
登録日2014-07-16
公開日2014-11-05
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014

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