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5GGS
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BU of 5ggs by Molmil
PD-1 in complex with pembrolizumab Fab
分子名称: Programmed cell death protein 1, heavy chain, light chain
著者Heo, Y.S.
登録日2016-06-16
公開日2016-11-09
最終更新日2016-11-16
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
5GGT
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BU of 5ggt by Molmil
PD-L1 in complex with BMS-936559 Fab
分子名称: IGK@ protein, IgG H chain, Programmed cell death 1 ligand 1
著者Heo, Y.S.
登録日2016-06-16
公開日2016-11-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
5GGR
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BU of 5ggr by Molmil
PD-1 in complex with nivolumab Fab
分子名称: Programmed cell death protein 1, heavy chain, light chain
著者Heo, Y.S.
登録日2016-06-16
公開日2016-11-09
最終更新日2016-11-16
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
5GGQ
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BU of 5ggq by Molmil
Crystal structure of Nivolumab Fab fragment
分子名称: nivolumab heavy chain, nivolumab light chain
著者Heo, Y.S.
登録日2016-06-16
公開日2016-11-09
最終更新日2016-11-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
5GGV
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BU of 5ggv by Molmil
CTLA-4 in complex with tremelimumab Fab
分子名称: Cytotoxic T-lymphocyte protein 4, heavy chain, light chain
著者Heo, Y.S.
登録日2016-06-16
公開日2016-11-09
最終更新日2016-11-16
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
4I0H
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BU of 4i0h by Molmil
SPR and structural analysis yield insight towards mechanism of inhibition of BACE inhibitors.
分子名称: (2R)-5-{[(2S,3R)-4-{[1-(3-tert-butylphenyl)cyclohexyl]amino}-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]amino}-2-hydroxy-5-oxopentanoic acid, Beta-secretase 1
著者Yao, N, Brecht, E.
登録日2012-11-16
公開日2013-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献SPR and structural analysis yield insight towards mechanism of inhibition of BACE inhibitors
To be Published
2ZBI
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BU of 2zbi by Molmil
Crystal structure of a bacterial cell-surface flagellin
分子名称: Flagellin homolog
著者Maruyama, Y.
登録日2007-10-22
公開日2008-02-05
最終更新日2018-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a novel bacterial cell-surface flagellin binding to a polysaccharide
Biochemistry, 47, 2008
2ZZR
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BU of 2zzr by Molmil
Crystal structure of unsaturated glucuronyl hydrolase from Streptcoccus agalactiae
分子名称: GLYCEROL, SULFATE ION, Unsaturated glucuronyl hydrolase
著者Maruyama, Y.
登録日2009-02-24
公開日2009-04-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Substrate specificity of streptococcal unsaturated glucuronyl hydrolases for sulfated glycosaminoglycan
J.Biol.Chem., 284, 2009
4I0I
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BU of 4i0i by Molmil
SPR and structural analysis yield insight towards mechanism of inhibition of BACE inhibitors
分子名称: Beta-secretase 1, N-[(1S,2R)-1-(3,5-difluorobenzyl)-3-({1-[4-(2,2-dimethylpropyl)thiophen-2-yl]cyclopropyl}amino)-2-hydroxypropyl]acetamide
著者Yao, N, Brecht, E.
登録日2012-11-16
公開日2013-11-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献SPR and structural analysis yield insight towards mechanism of inhibition of BACE inhibitors
To be Published
1QAZ
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BU of 1qaz by Molmil
CRYSTAL STRUCTURE OF ALGINATE LYASE A1-III FROM SPHINGOMONAS SPECIES A1 AT 1.78A RESOLUTION
分子名称: PROTEIN (ALGINATE LYASE A1-III), SULFATE ION
著者Yoon, H.-J.
登録日1999-04-08
公開日1999-07-19
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal structure of alginate lyase A1-III from Sphingomonas species A1 at 1.78 A resolution.
J.Mol.Biol., 290, 1999
4OW5
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BU of 4ow5 by Molmil
Structural basis for the enhancement of virulence by entomopoxvirus fusolin and its in vivo crystallization into viral spindles
分子名称: 1,2-ETHANEDIOL, Fusolin
著者Hijnen, M, Boudes, M, Aizel, K, Coulibaly, F.
登録日2014-01-31
公開日2015-03-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the enhancement of virulence by viral spindles and their in vivo crystallization.
Proc.Natl.Acad.Sci.USA, 112, 2015
5X8M
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BU of 5x8m by Molmil
PD-L1 in complex with durvalumab
分子名称: Programmed cell death 1 ligand 1, durvalumab heavy chain, durvalumab light chain
著者Heo, Y.S, Lee, H.T.
登録日2017-03-03
公開日2017-08-16
実験手法X-RAY DIFFRACTION (2.661 Å)
主引用文献Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab
Sci Rep, 7, 2017
5X8L
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BU of 5x8l by Molmil
PD-L1 in complex with atezolizumab
分子名称: Programmed cell death 1 ligand 1, atezolizumab heavy chain, atezolizumab light chain
著者Heo, Y.S, Lee, H.T.
登録日2017-03-03
公開日2017-08-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab
Sci Rep, 7, 2017
5WUX
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BU of 5wux by Molmil
TNFalpha-certolizumab Fab
分子名称: Tumor necrosis factor alpha, heavy, light
著者Heo, Y.S, Lee, J.U.
登録日2016-12-21
公開日2017-06-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Molecular Basis for the Neutralization of Tumor Necrosis Factor alpha by Certolizumab Pegol in the Treatment of Inflammatory Autoimmune Diseases
Int J Mol Sci, 18, 2017
6L49
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BU of 6l49 by Molmil
H3-CA-H3 tri-nucleosome with the 22 base-pair linker DNA
分子名称: DNA (485-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Takizawa, Y, Ho, C.-H, Tachiwana, H, Matsunami, H, Ohi, M, Wolf, M, Kurumizaka, H.
登録日2019-10-16
公開日2019-12-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (18.9 Å)
主引用文献Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome.
Structure, 28, 2020
6L4A
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BU of 6l4a by Molmil
H3-H3-H3 tri-nucleosome with the 22 base-pair linker DNA
分子名称: DNA (485-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Takizawa, Y, Ho, C.-H, Tachiwana, H, Matsunami, H, Ohi, M, Wolf, M, Kurumizaka, H.
登録日2019-10-16
公開日2019-12-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (12.3 Å)
主引用文献Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome.
Structure, 28, 2020
2ME4
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BU of 2me4 by Molmil
HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle
分子名称: Envelope glycoprotein gp160
著者Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W.
登録日2013-09-20
公開日2013-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
2ME1
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BU of 2me1 by Molmil
HIV-1 gp41 clade B double alanine mutant Membrane Proximal External Region peptide in DPC micelle
分子名称: Gp41
著者Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W.
登録日2013-09-20
公開日2013-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
2ME2
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BU of 2me2 by Molmil
HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle
分子名称: Envelope glycoprotein gp160
著者Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W.
登録日2013-09-20
公開日2013-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
2ME3
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BU of 2me3 by Molmil
HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle
分子名称: Envelope glycoprotein gp160
著者Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W.
登録日2013-09-20
公開日2013-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
7KHD
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BU of 7khd by Molmil
Human GITR-GITRL complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 18, Tumor necrosis factor receptor superfamily member 18
著者Wang, F, Chau, B, West, S.M, Strop, P.
登録日2020-10-21
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.956102 Å)
主引用文献Structures of mouse and human GITR-GITRL complexes reveal unique TNF superfamily interactions.
Nat Commun, 12, 2021
7KHX
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BU of 7khx by Molmil
Mouse GITR-GITRL complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 18, ...
著者Wang, F, Chau, B, West, S.M, Strop, P.
登録日2020-10-22
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.20569849 Å)
主引用文献Structures of mouse and human GITR-GITRL complexes reveal unique TNF superfamily interactions.
Nat Commun, 12, 2021
3WE7
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BU of 3we7 by Molmil
Crystal Structure of Diacetylchitobiose Deacetylase from Pyrococcus horikoshii
分子名称: ACETIC ACID, GLYCEROL, HEXANE-1,6-DIOL, ...
著者Mine, S, Nakamura, T, Fukuda, Y, Inoue, T, Uegaki, K, Sato, T.
登録日2013-07-01
公開日2014-05-07
最終更新日2014-08-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Expression from engineered Escherichia coli chromosome and crystallographic study of archaeal N,N'-diacetylchitobiose deacetylase
Febs J., 281, 2014
2DUC
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BU of 2duc by Molmil
Crystal structure of SARS coronavirus main proteinase(3CLPRO)
分子名称: Replicase polyprotein 1ab
著者Wang, H, Kim, Y.T, Muramatsu, T, Takemoto, C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-07-21
公開日2007-07-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献SARS-CoV 3CL protease cleaves its C-terminal autoprocessing site by novel subsite cooperativity
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
2E9B
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BU of 2e9b by Molmil
Crystal structure of pullulanase type I from Bacillus subtilis str. 168 complexed with maltose
分子名称: ACETATE ION, AmyX protein, CALCIUM ION, ...
著者Mikami, B, Malle, D, Utsumi, S, Iwamoto, H, Katsuya, Y.
登録日2007-01-24
公開日2008-02-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of pullulanase type I from Bacillus subtilis str. 168 in complex with maltose and alpha-cyclodextrin
To be Published

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