7KHD
| Human GITR-GITRL complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 18, Tumor necrosis factor receptor superfamily member 18 | 著者 | Wang, F, Chau, B, West, S.M, Strop, P. | 登録日 | 2020-10-21 | 公開日 | 2021-03-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.956102 Å) | 主引用文献 | Structures of mouse and human GITR-GITRL complexes reveal unique TNF superfamily interactions. Nat Commun, 12, 2021
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7KHX
| Mouse GITR-GITRL complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 18, ... | 著者 | Wang, F, Chau, B, West, S.M, Strop, P. | 登録日 | 2020-10-22 | 公開日 | 2021-03-03 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.20569849 Å) | 主引用文献 | Structures of mouse and human GITR-GITRL complexes reveal unique TNF superfamily interactions. Nat Commun, 12, 2021
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5GGV
| CTLA-4 in complex with tremelimumab Fab | 分子名称: | Cytotoxic T-lymphocyte protein 4, heavy chain, light chain | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2016-11-16 | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGR
| PD-1 in complex with nivolumab Fab | 分子名称: | Programmed cell death protein 1, heavy chain, light chain | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2016-11-16 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGQ
| Crystal structure of Nivolumab Fab fragment | 分子名称: | nivolumab heavy chain, nivolumab light chain | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGT
| PD-L1 in complex with BMS-936559 Fab | 分子名称: | IGK@ protein, IgG H chain, Programmed cell death 1 ligand 1 | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGU
| Crystal structure of tremelimumab Fab | 分子名称: | heavy chain, light chain | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2016-11-16 | 実験手法 | X-RAY DIFFRACTION (2.292 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGS
| PD-1 in complex with pembrolizumab Fab | 分子名称: | Programmed cell death protein 1, heavy chain, light chain | 著者 | Heo, Y.S. | 登録日 | 2016-06-16 | 公開日 | 2016-11-09 | 最終更新日 | 2016-11-16 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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1QAZ
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6L49
| H3-CA-H3 tri-nucleosome with the 22 base-pair linker DNA | 分子名称: | DNA (485-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Takizawa, Y, Ho, C.-H, Tachiwana, H, Matsunami, H, Ohi, M, Wolf, M, Kurumizaka, H. | 登録日 | 2019-10-16 | 公開日 | 2019-12-04 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (18.9 Å) | 主引用文献 | Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome. Structure, 28, 2020
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4I0J
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8J8Z
| Structure of beta-arrestin1 in complex with D6Rpp | 分子名称: | Atypical chemokine receptor 2, Beta-arrestin-1, Fab30 Heavy Chain, ... | 著者 | Maharana, J, Sarma, P, Yadav, M.K, Chami, M, Banerjee, R, Shukla, A.K. | 登録日 | 2023-05-02 | 公開日 | 2023-12-27 | 最終更新日 | 2024-01-17 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8J9K
| Structure of basal beta-arrestin2 | 分子名称: | Beta-arrestin-2, Fab6 heavy chain, Fab6 light chain | 著者 | Maharana, J, Sarma, P, Yadav, M.K, Chami, M, Banerjee, R, Shukla, A.K. | 登録日 | 2023-05-03 | 公開日 | 2023-12-27 | 最終更新日 | 2024-01-17 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8J8V
| Structure of beta-arrestin2 in complex with D6Rpp (Local Refine) | 分子名称: | Atypical chemokine receptor 2, Beta-arrestin-2, Fab30 Heavy Chain, ... | 著者 | Maharana, J, Sarma, P, Yadav, M.K, Chami, M, Banerjee, R, Shukla, A.K. | 登録日 | 2023-05-02 | 公開日 | 2023-12-27 | 最終更新日 | 2024-01-17 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8JA3
| Structure of beta-arrestin1 in complex with C3aRpp | 分子名称: | Beta-arrestin-1, C3a anaphylatoxin chemotactic receptor, Fab30 heavy chain, ... | 著者 | Maharana, J, Sarma, P, Yadav, M.K, Chami, M, Banerjee, R, Shukla, A.K. | 登録日 | 2023-05-05 | 公開日 | 2023-12-27 | 最終更新日 | 2024-01-17 | 実験手法 | ELECTRON MICROSCOPY (3.94 Å) | 主引用文献 | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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6L4A
| H3-H3-H3 tri-nucleosome with the 22 base-pair linker DNA | 分子名称: | DNA (485-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Takizawa, Y, Ho, C.-H, Tachiwana, H, Matsunami, H, Ohi, M, Wolf, M, Kurumizaka, H. | 登録日 | 2019-10-16 | 公開日 | 2019-12-04 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (12.3 Å) | 主引用文献 | Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome. Structure, 28, 2020
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4I0H
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4I0I
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5X02
| Crystal structure of the FLT3 kinase domain bound to the inhibitor FF-10101 | 分子名称: | N-[(2S)-1-[5-[2-[(4-cyanophenyl)amino]-4-(propylamino)pyrimidin-5-yl]pent-4-ynylamino]-1-oxidanylidene-propan-2-yl]-4-(dimethylamino)-N-methyl-but-2-enamide, Receptor-type tyrosine-protein kinase FLT3, SULFATE ION | 著者 | Fujikawa, N, Hirano, D, Takasaki, M, Terada, D, Hagiwara, S, Park, S.-Y, Sugiyama, K. | 登録日 | 2017-01-19 | 公開日 | 2018-01-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | A novel irreversible FLT3 inhibitor, FF-10101, shows excellent efficacy against AML cells withFLT3mutations. Blood, 131, 2018
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2ZBI
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2ZZR
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2ME4
| HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle | 分子名称: | Envelope glycoprotein gp160 | 著者 | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | 登録日 | 2013-09-20 | 公開日 | 2013-10-09 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41. J.Mol.Biol., 426, 2014
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2ME1
| HIV-1 gp41 clade B double alanine mutant Membrane Proximal External Region peptide in DPC micelle | 分子名称: | Gp41 | 著者 | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | 登録日 | 2013-09-20 | 公開日 | 2013-10-09 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41. J.Mol.Biol., 426, 2014
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2ME2
| HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle | 分子名称: | Envelope glycoprotein gp160 | 著者 | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | 登録日 | 2013-09-20 | 公開日 | 2013-10-09 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41. J.Mol.Biol., 426, 2014
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2ME3
| HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle | 分子名称: | Envelope glycoprotein gp160 | 著者 | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | 登録日 | 2013-09-20 | 公開日 | 2013-10-09 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41. J.Mol.Biol., 426, 2014
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