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1IP0
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NMR STRUCTURE OF HUMAN BETACELLULIN-2
分子名称: BETACELLULIN
著者Miura, K, Doura, H, Aizawa, T, Tada, H, Seno, M, Yamada, H, Kawano, K.
登録日2001-04-19
公開日2002-07-31
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of betacellulin, a new member of EGF-family ligands.
Biochem.Biophys.Res.Commun., 294, 2002
1IOX
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BU of 1iox by Molmil
NMR Structure of human Betacellulin-2
分子名称: Betacellulin
著者Miura, K, Doura, H, Aizawa, T, Tada, H, Seno, M, Yamada, H, Kawano, K.
登録日2001-04-18
公開日2002-07-24
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of betacellulin, a new member of EGF-family ligands.
Biochem.Biophys.Res.Commun., 294, 2002
1LJZ
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BU of 1ljz by Molmil
NMR structure of an AChR-peptide (Torpedo Californica, alpha-subunit residues 182-202) in complex with alpha-Bungarotoxin
分子名称: Acetylcholine receptor protein, alpha-Bungarotoxin
著者Samson, A.O, Scherf, T, Eisenstein, M, Chill, J.H, Anglister, J.
登録日2002-04-23
公開日2002-07-17
最終更新日2013-07-24
実験手法SOLUTION NMR
主引用文献The mechanism for acetylcholine receptor inhibition by alpha-neurotoxins and species-specific resistance to alpha-bungarotoxin revealed by NMR.
Neuron, 35, 2002
1L4W
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BU of 1l4w by Molmil
NMR structure of an AChR-peptide (Torpedo Californica, alpha-subunit residues 182-202) in complex with alpha-Bungarotoxin
分子名称: Acetylcholine receptor protein, alpha-Bungarotoxin
著者Samson, A.O, Scherf, T, Rodriguez, E, Eisenstein, M, Anglister, J.
登録日2002-03-06
公開日2002-07-17
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献The mechanism for acetylcholine receptor inhibition by alpha-neurotoxins and species-specific resistance to alpha-bungarotoxin revealed by NMR.
Neuron, 35, 2002
1LO5
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BU of 1lo5 by Molmil
Crystal structure of the D227A variant of Staphylococcal enterotoxin A in complex with human MHC class II
分子名称: HLA class II histocompatibility antigen, DR alpha chain, DR-1 beta chain, ...
著者Petersson, K, Thunnissen, M, Forsberg, G, Walse, B.
登録日2002-05-06
公開日2002-12-18
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal Structure of a SEA Variant in Complex with MHC Class II Reveals the Ability of SEA to Crosslink MHC Molecules
Structure, 10, 2002
3DN5
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BU of 3dn5 by Molmil
Aldose Reductase in complex with novel biarylic inhibitor
分子名称: 3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Steuber, H, Klebe, G.
登録日2008-07-01
公開日2009-04-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure-Based Optimization of Aldose Reductase Inhibitors Originating from Virtual Screening
Chemmedchem, 4, 2009
2K37
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BU of 2k37 by Molmil
CsmA
分子名称: Chlorosome Protein A
著者Pedersen, M, Dittmer, J, Underhaug, J, Miller, M, Nielsen, N.C.
登録日2008-04-23
公開日2008-09-02
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献The three-dimensional structure of CsmA: A small antenna protein from the green sulfur bacterium Chlorobium tepidum.
Febs Lett., 582, 2008
2POX
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BU of 2pox by Molmil
Dark state structure of the reversibly switchable fluorescent protein Dronpa
分子名称: Fluorescent protein Dronpa
著者Trowitzsch, S, Weber, G, Wahl, M.C.
登録日2007-04-27
公開日2007-07-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.946 Å)
主引用文献Structural basis for reversible photoswitching in Dronpa
Proc.Natl.Acad.Sci.Usa, 104, 2007
7P2D
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BU of 7p2d by Molmil
Structure of alphaMbeta2/Cd11bCD18 headpiece in complex with a nanobody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Jensen, R.K, Andersen, G.R.
登録日2021-07-05
公開日2022-05-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural insights into the function-modulating effects of nanobody binding to the integrin receptor alpha M beta 2.
J.Biol.Chem., 298, 2022
7XIM
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BU of 7xim by Molmil
PROTEIN ENGINEERING OF XYLOSE (GLUCOSE) ISOMERASE FROM ACTINOPLANES MISSOURIENSIS. 1. CRYSTALLOGRAPHY AND SITE-DIRECTED MUTAGENESIS OF METAL BINDING SITES
分子名称: D-XYLOSE ISOMERASE
著者Janin, J.
登録日1992-04-03
公開日1993-07-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites.
Biochemistry, 31, 1992
3CHQ
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BU of 3chq by Molmil
Crystal structure of leukotriene a4 hydrolase in complex with N5-[4-(phenylmethoxy)phenyl]-L-glutamine
分子名称: (2S)-2-amino-5-oxo-5-[(4-phenylmethoxyphenyl)amino]pentanoic acid, IMIDAZOLE, Leukotriene A-4 hydrolase, ...
著者Thunnissen, M.M.G.M, Adler, M, Whitlow, M.
登録日2008-03-10
公開日2008-04-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase.
Bioorg.Med.Chem., 16, 2008
3CHR
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BU of 3chr by Molmil
Crystal structure of leukotriene A4 hydrolase in complex with 4-amino-N-[4-(phenylmethoxy)phenyl]-butanamide
分子名称: 4-amino-N-[4-(benzyloxy)phenyl]butanamide, IMIDAZOLE, Leukotriene A-4 hydrolase, ...
著者Thunnissen, M.M.G.M, Adler, M, Whitlow, M.
登録日2008-03-10
公開日2008-04-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase.
Bioorg.Med.Chem., 16, 2008
1VST
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BU of 1vst by Molmil
Symmetric Sulfolobus solfataricus uracil phosphoribosyltransferase with bound PRPP and GTP
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kadziola, A.
登録日2009-02-09
公開日2009-09-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and kinetic studies of the allosteric transition in Sulfolobus solfataricus uracil phosphoribosyltransferase: Permanent activation by engineering of the C-terminus
J.Mol.Biol., 393, 2009
6YO6
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BU of 6yo6 by Molmil
Structure of iC3b1
分子名称: hC3Nb1, iC3b1 alpha chain, iC3b1 beta chain
著者Jensen, R.K, Andersen, G.R.
登録日2020-04-14
公開日2021-02-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (6 Å)
主引用文献Complement Receptor 3 Forms a Compact High-Affinity Complex with iC3b.
J Immunol., 206, 2021
4X08
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BU of 4x08 by Molmil
Structure of H128N/ECP mutant in complex with sulphate anions at 1.34 Angstroms.
分子名称: Eosinophil cationic protein, SULFATE ION
著者Blanco, J.A, Garcia, J.M, Salazar, V.A, Sanchez, D, Moussauoi, M, Boix, E.
登録日2014-11-21
公開日2015-10-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Structure of H128N/ECP mutant in complex with sulphate anions at 1.34 Angstroms.
To Be Published
5LJM
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BU of 5ljm by Molmil
Structure of SPATA2 PUB domain
分子名称: GLYCEROL, Spermatogenesis-associated protein 2
著者Elliott, P.R, Komander, D.
登録日2016-07-18
公開日2016-08-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.454 Å)
主引用文献SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.
Mol.Cell, 63, 2016
6DCV
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BU of 6dcv by Molmil
Crystal structure of human anti-tau antibody CBTAU-27.1
分子名称: GLYCEROL, Light chain of CBTAU27.1 Fab, heavy chain of CBTAU-27.1 Fab
著者Zhu, X, Zhang, H, Wilson, I.A.
登録日2018-05-08
公開日2018-06-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.
Acta Neuropathol Commun, 6, 2018
6DCW
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Crystal structure of human anti-tau antibody CBTAU-27.1 Fab in complex with a human tau peptide
分子名称: Heavy chain of CBTAU27.1 Fab, Light chain of CBTAU27.1 Fab, tau peptide
著者Zhu, X, Zhang, H, Wilson, I.A.
登録日2018-05-08
公開日2018-06-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.
Acta Neuropathol Commun, 6, 2018
3T3P
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A Novel High Affinity Integrin alphaIIbbeta3 Receptor Antagonist That Unexpectedly Displaces Mg2+ from the beta3 MIDAS
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Zhu, J, Zhu, J, Springer, T.A.
登録日2011-07-25
公開日2012-03-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure-Guided Design of a High-Affinity Platelet Integrin alphaIIbbeta3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDAS
Sci Transl Med, 4, 2012
3T3M
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A Novel High Affinity Integrin alphaIIbbeta3 Receptor Antagonist That Unexpectedly Displaces Mg2+ from the beta3 MIDAS
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Zhu, J, Zhu, J, Springer, T.A.
登録日2011-07-25
公開日2012-03-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-Guided Design of a High-Affinity Platelet Integrin alphaIIbbeta3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDAS
Sci Transl Med, 4, 2012
8GCE
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BU of 8gce by Molmil
The Extracellular Domain of Integrin AlphaIIbBeta3 in Intermediate State
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Huo, T, Wu, H, Wang, Z.
登録日2023-03-01
公開日2024-03-06
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Full-length alpha IIb beta 3 cryo-EM structure reveals intact integrin initiate-activation intrinsic architecture.
Structure, 32, 2024
8GCD
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Full length Integrin AlphaIIbBeta3 in inactive state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Huo, T, Wu, H, Wang, Z.
登録日2023-03-01
公開日2024-03-06
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Full-length alpha IIb beta 3 cryo-EM structure reveals intact integrin initiate-activation intrinsic architecture.
Structure, 32, 2024
4UX9
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Crystal structure of JNK1 bound to a MKK7 docking motif
分子名称: DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 7, MITOGEN-ACTIVATED PROTEIN KINASE 8, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Kragelj, J, Palencia, A, Nanao, M.H, Maurin, D, Bouvignies, G, Blackledge, M, Ringkjobing-Jensen, M.
登録日2014-08-20
公開日2015-03-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Structure and Dynamics of the Mkk7-Jnk Signaling Complex.
Proc.Natl.Acad.Sci.USA, 112, 2015
9XIM
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BU of 9xim by Molmil
PROTEIN ENGINEERING OF XYLOSE (GLUCOSE) ISOMERASE FROM ACTINOPLANES MISSOURIENSIS. 1. CRYSTALLOGRAPHY AND SITE-DIRECTED MUTAGENESIS OF METAL BINDING SITES
分子名称: D-XYLOSE ISOMERASE, D-xylose, MANGANESE (II) ION
著者Janin, J.
登録日1992-04-03
公開日1993-07-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites.
Biochemistry, 31, 1992
7O6U
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Crystal structure of the VIN3 VEL polymerising domain (R554A R556D mutant)
分子名称: Protein VERNALIZATION INSENSITIVE 3
著者Fiedler, M, Franco-Echevarria, E, Dean, C, Bienz, M.
登録日2021-04-12
公開日2022-11-09
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Cell Rep, 41, 2022

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