6DRX
 
 | | Structural Determinants of Activation and Biased Agonism at the 5-HT2B Receptor | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 5HT2B receptor, BRIL chimera, ... | | 著者 | McCorvy, J.D, Wacker, D, Wang, S, Agegnehu, B, Liu, J, Lansu, K, Tribo, A.R, Olsen, R.H.J, Che, T, Jin, J, Roth, B.L. | | 登録日 | 2018-06-13 | | 公開日 | 2018-08-29 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural determinants of 5-HT2Breceptor activation and biased agonism.
Nat. Struct. Mol. Biol., 25, 2018
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6DS0
 | | Structural Determinants of Activation and Biased Agonism at the 5-HT2B Receptor | | 分子名称: | (1S)-1-[(2-chloro-3,4-dimethoxyphenyl)methyl]-6-methyl-2,3,4,9-tetrahydro-1H-beta-carboline, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 5HT2B receptor, ... | | 著者 | McCorvy, J.D, Wacker, D, Wang, S, Agegnehu, B, Liu, J, Lansu, K, Tribo, A.R, Olsen, R.H.J, Che, T, Jin, J, Roth, B.L. | | 登録日 | 2018-06-13 | | 公開日 | 2018-08-29 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.188 Å) | | 主引用文献 | Structural determinants of 5-HT2Breceptor activation and biased agonism.
Nat. Struct. Mol. Biol., 25, 2018
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5TSB
 | | Crystal structure of the Zrt-/Irt-like protein from Bordetella bronchiseptica with bound Cd2+ | | 分子名称: | CADMIUM ION, Membrane protein | | 著者 | Zhang, T, Fellner, M, Sui, D, Liu, J, Hu, J. | | 登録日 | 2016-10-28 | | 公開日 | 2017-09-20 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway.
Sci Adv, 3, 2017
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5TSA
 | | Crystal structure of the Zrt-/Irt-like protein from Bordetella bronchiseptica with bound Zn2+ | | 分子名称: | CADMIUM ION, Membrane protein, ZINC ION | | 著者 | Zhang, T, Fellner, M, Sui, D, Liu, J, Hu, J. | | 登録日 | 2016-10-28 | | 公開日 | 2017-09-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway.
Sci Adv, 3, 2017
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5V9I
 | | Crystal structure of catalytic domain of G9a with MS0105 | | 分子名称: | GLYCEROL, Histone-lysine N-methyltransferase EHMT2, N~2~-cyclohexyl-N~4~-(1-ethylpiperidin-4-yl)-6,7-dimethoxy-N~2~-methylquinazoline-2,4-diamine, ... | | 著者 | Dong, A, Zeng, H, Liu, J, Xiong, Y, Babault, N, Jin, J, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Wu, H, Brown, P.J, Structural Genomics Consortium (SGC) | | 登録日 | 2017-03-23 | | 公開日 | 2018-03-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Crystal structure of catalytic domain of G9a with MS0105
to be published
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4FDB
 | | Three-dimensional structure of the protein prib from ralstonia solanacearum at the resolution 1.8a. northeast structural genomics consortium target rsr213c | | 分子名称: | ACETIC ACID, Probable primosomal replication protein n | | 著者 | Kuzin, A, Neely, H, Seetharaman, J, Wang, H, Sahdev, S, Foote, E.L, Xiao, R, Liu, J, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2012-05-27 | | 公開日 | 2013-02-13 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Three-dimensional structure of the protein prib from ralstonia solanacearum at the resolution 1.8a. northeast structural genomics consortium target rsr213c
To be Published
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5V9J
 | | Crystal structure of catalytic domain of GLP with MS0105 | | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, Histone-lysine N-methyltransferase EHMT1, ... | | 著者 | Dong, A, Zeng, H, Liu, J, Xiong, Y, Babault, N, Jin, J, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Wu, H, Brown, P.J, Structural Genomics Consortium (SGC) | | 登録日 | 2017-03-23 | | 公開日 | 2018-03-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Crystal structure of catalytic domain of GLP with MS0105
to be published
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5VSC
 | | Structure of human G9a SET-domain (EHMT2) in complex with inhibitor 13 | | 分子名称: | 6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)-N~2~-propylquinazoline-2,4-diamine, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ... | | 著者 | Babault, N, Xiong, Y, Liu, J, Jin, J. | | 登録日 | 2017-05-11 | | 公開日 | 2017-07-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure-activity relationship studies of G9a-like protein (GLP) inhibitors.
Bioorg. Med. Chem., 25, 2017
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1IMX
 | | 1.8 Angstrom crystal structure of IGF-1 | | 分子名称: | BROMIDE ION, Insulin-like Growth Factor 1A, N,N-BIS(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE | | 著者 | Vajdos, F.F, Ultsch, M, Schaffer, M.L, Deshayes, K.D, Liu, J, Skelton, N.J, de Vos, A.M. | | 登録日 | 2001-05-11 | | 公開日 | 2001-09-05 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Crystal structure of human insulin-like growth factor-1: detergent binding inhibits binding protein interactions.
Biochemistry, 40, 2001
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1LB2
 | | Structure of the E. coli alpha C-terminal domain of RNA polymerase in complex with CAP and DNA | | 分子名称: | 5'-D(*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*TP*TP*TP*AP*GP*GP*AP*AP*AP*AP*AP*AP*G)-3', 5'-D(*CP*TP*TP*TP*TP*TP*TP*CP*CP*TP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ... | | 著者 | Benoff, B, Yang, H, Lawson, C.L, Parkinson, G, Liu, J, Blatter, E, Ebright, Y.W, Berman, H.M, Ebright, R.H. | | 登録日 | 2002-04-01 | | 公開日 | 2002-09-06 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis of transcription activation: the CAP-alpha CTD-DNA complex.
Science, 297, 2002
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5GW0
 | | Crystal structure of SNX16 PX-Coiled coil | | 分子名称: | Sorting nexin-16 | | 著者 | Xu, J, Liu, J. | | 登録日 | 2016-09-08 | | 公開日 | 2017-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | SNX16 Regulates the Recycling of E-Cadherin through a Unique Mechanism of Coordinated Membrane and Cargo Binding.
Structure, 25, 2017
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5GW1
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1N6H
 | | Crystal Structure of Human Rab5a | | 分子名称: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | | 登録日 | 2002-11-11 | | 公開日 | 2002-11-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop
J.Biol.Chem., 278, 2003
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1N6I
 | | Crystal Structure of Human Rab5a A30P mutant Complex with GDP | | 分子名称: | BETA-MERCAPTOETHANOL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | | 登録日 | 2002-11-11 | | 公開日 | 2002-11-27 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop
J.Biol.Chem., 278, 2003
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1N6K
 | | Crystal Structure of Human Rab5a A30P mutant complex with GDP and aluminum fluoride | | 分子名称: | ALUMINUM FLUORIDE, BETA-MERCAPTOETHANOL, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | | 登録日 | 2002-11-11 | | 公開日 | 2002-11-27 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop
J.Biol.Chem., 278, 2003
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1N6L
 | | Crystal Structure of Human Rab5a A30P mutant complex with GTP | | 分子名称: | BETA-MERCAPTOETHANOL, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | | 登録日 | 2002-11-11 | | 公開日 | 2002-11-27 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop
J.Biol.Chem., 278, 2003
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1N6O
 | | Crystal Structure of Human Rab5a A30K mutant complex with GppNHp | | 分子名称: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | | 登録日 | 2002-11-11 | | 公開日 | 2002-11-27 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop
J.Biol.Chem., 278, 2003
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1N6N
 | | Crystal Structure of Human Rab5a A30R mutant complex with GppNHp | | 分子名称: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | | 登録日 | 2002-11-11 | | 公開日 | 2002-11-27 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop
J.Biol.Chem., 278, 2003
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1N6P
 | | Crystal Structure of Human Rab5a A30E mutant complex with GppNHp | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-5A | | 著者 | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | | 登録日 | 2002-11-11 | | 公開日 | 2002-11-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop
J.Biol.Chem., 278, 2003
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1N6R
 | | Crystal Structure of Human Rab5a A30L mutant complex with GppNHp | | 分子名称: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | | 登録日 | 2002-11-11 | | 公開日 | 2002-11-27 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop
J.Biol.Chem., 278, 2003
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4LLA
 | | Crystal structure of D3D4 domain of the LILRB2 molecule | | 分子名称: | Leukocyte immunoglobulin-like receptor subfamily B member 2 | | 著者 | Nam, G, Shi, Y, Ryu, M, Wang, Q, Song, H, Liu, J, Yan, J, Qi, J, Gao, G.F. | | 登録日 | 2013-07-09 | | 公開日 | 2013-09-11 | | 最終更新日 | 2013-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | | 主引用文献 | Crystal structures of the two membrane-proximal Ig-like domains (D3D4) of LILRB1/B2: alternative models for their involvement in peptide-HLA binding
Protein Cell, 4, 2013
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4LL9
 | | Crystal structure of D3D4 domain of the LILRB1 molecule | | 分子名称: | IODIDE ION, Leukocyte immunoglobulin-like receptor subfamily B member 1 | | 著者 | Nam, G, Shi, Y, Ryu, M, Wang, Q, Song, H, Liu, J, Yan, J, Qi, J, Gao, G.F. | | 登録日 | 2013-07-09 | | 公開日 | 2013-09-11 | | 最終更新日 | 2013-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.686 Å) | | 主引用文献 | Crystal structures of the two membrane-proximal Ig-like domains (D3D4) of LILRB1/B2: alternative models for their involvement in peptide-HLA binding
Protein Cell, 4, 2013
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2MWN
 | | Talin-F3 / RIAM N-terminal Peptide complex | | 分子名称: | Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, Talin-1 | | 著者 | Yang, J, Zhu, L, Zhang, H, Hirbawi, J, Fukuda, K, Dwivedi, P, Liu, J, Byzova, T, Plow, E.F, Wu, J, Qin, J. | | 登録日 | 2014-11-13 | | 公開日 | 2014-12-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Conformational activation of talin by RIAM triggers integrin-mediated cell adhesion.
Nat Commun, 5, 2014
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3SWV
 | | Crystal Structure of a domain of Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2) from Homo sapiens (Human), Northeast Structural Genomics Consortium target id HR5562A | | 分子名称: | Brefeldin A-inhibited guanine nucleotide-exchange protein 2 | | 著者 | Seetharaman, J, Su, M, Forouhar, F, Wang, D, Janjua, H, Cunningham, K, Owens, L, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2011-07-14 | | 公開日 | 2011-08-24 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal Structure of a domain of Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BrefeldinA-inhibited GEP 2) from Homo sapiens (Human), Northeast Structural Genomics Consortium target id HR5562A
To be Published
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3TJ0
 | | Crystal Structure of Influenza B Virus Nucleoprotein | | 分子名称: | Nucleoprotein | | 著者 | Ng, A.K.L, Zhang, H, Liu, J, Au, S.W.N, Wang, J, Shaw, P.C. | | 登録日 | 2011-08-23 | | 公開日 | 2012-06-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.233 Å) | | 主引用文献 | Structural basis for RNA binding and homo-oligomer formation by influenza B virus nucleoprotein
J.Virol., 86, 2012
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