Crystal Structure of Human Rab5a A30P mutant complex with GTP

Summary for 1N6L

Related1N6H 1N6I 1N6K 1N6N 1N6O 1N6P 1N6R
DescriptorRas-related protein Rab-5A, MAGNESIUM ION, GUANOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
Functional Keywordsrab, gtpase, protein transport
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Lipid-anchor; Cytoplasmic side (By similarity) P20339
Total number of polymer chains1
Total molecular weight19639.23
Zhu, G.,Liu, J.,Terzyan, S.,Zhai, P.,Li, G.,Zhang, X.C. (deposition date: 2002-11-11, release date: 2002-11-27, Last modification date: 2011-07-13)
Primary citation
Zhu, G.,Liu, J.,Terzyan, S.,Zhai, P.,Li, G.,Zhang, X.C.
High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop
J.Biol.Chem., 278:2452-2460, 2003
PubMed: 12433916 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M211042200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2037 1.2%0 3.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-12-02