7CAH
 
 | | The interface of H014 Fab binds to SARS-CoV-2 S | | 分子名称: | Heavy chain of H014 Fab, Light chain of H014 Fab, Spike protein S1 | | 著者 | Zhe, L, Cao, L, Deng, Y, Sun, Y, Wang, N, Xie, L, Rao, Z, wang, Y, Qin, C, Wang, X. | | 登録日 | 2020-06-08 | | 公開日 | 2020-08-12 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody.
Science, 369, 2020
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7CAK
 | | SARS-CoV-2 S trimer with three RBD in the open state and complexed with three H014 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of H014 Fab, ... | | 著者 | Zhe, L, Cao, L, Deng, Y, Sun, Y, Wang, N, Xie, L, Wang, Y, Rao, Z, Qin, C, Wang, X. | | 登録日 | 2020-06-08 | | 公開日 | 2020-09-23 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody.
Science, 369, 2020
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9BQJ
 | | RO76 bound muOR-Gi1-scFv16 complex structure | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Wang, H, Majumdar, S, Kobilka, B.K. | | 登録日 | 2024-05-10 | | 公開日 | 2024-09-11 | | 最終更新日 | 2025-05-21 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Signaling Modulation Mediated by Ligand Water Interactions with the Sodium Site at mu OR.
Acs Cent.Sci., 10, 2024
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8VLF
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8VLD
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8VLH
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8CJ7
 | | HDAC6 selective degraded (difluoromethyl)-1,3,4-oxadiazole substrate inhibitor | | 分子名称: | 6-[(5-pyridin-2-yl-1,2$l^{4},3,4-tetrazacyclopenta-1,3-dien-2-yl)methyl]pyridine-3-carbohydrazide, Histone deacetylase 6, IODIDE ION, ... | | 著者 | Sandmark, J, Ek, M, Ripa, L. | | 登録日 | 2023-02-12 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Selective and Bioavailable HDAC6 2-(Difluoromethyl)-1,3,4-oxadiazole Substrate Inhibitors and Modeling of Their Bioactivation Mechanism.
J.Med.Chem., 66, 2023
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8W51
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8X7T
 | | MCM in the Apo state. | | 分子名称: | mini-chromosome maintenance complex 3 | | 著者 | Ma, J, Yi, G, Ye, M, MacGregor-Chatwin, C, Sheng, Y, Lu, Y, Li, M, Gilbert, R.J.C, Zhang, P. | | 登録日 | 2023-11-25 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Open architecture of archaea MCM and dsDNA complexes resolved using monodispersed streptavidin affinity CryoEM.
Nat Commun, 15, 2024
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8X7U
 | | MCM in complex with dsDNA in presence of ATP. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Ma, J, Yi, G, Ye, M, MacGregor-Chatwin, C, Sheng, Y, Lu, Y, Li, M, Gilbert, R.J.C, Zhang, P. | | 登録日 | 2023-11-25 | | 公開日 | 2024-01-17 | | 最終更新日 | 2025-01-01 | | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | | 主引用文献 | Open architecture of archaea MCM and dsDNA complexes resolved using monodispersed streptavidin affinity CryoEM.
Nat Commun, 15, 2024
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2GHG
 | | h-CHK1 complexed with A431994 | | 分子名称: | 5-{5-[(S)-2-AMINO-3-(1H-INDOL-3-YL)-PROPOXYL]-PYRIDIN-3-YL}-3-[1-(1H-PYRROL-2-YL)-METH-(Z)-YLIDENE]-1,3-DIHYDRO-INDOL-2-ONE, Serine/threonine-protein kinase Chk1 | | 著者 | Park, C. | | 登録日 | 2006-03-27 | | 公開日 | 2007-03-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Discovery and SAR of oxindole-pyridine-based protein kinase B/Akt inhibitors for treating cancers.
Bioorg.Med.Chem.Lett., 16, 2006
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3H00
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3H01
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3GWO
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2KGL
 | | NMR solution structure of MESD | | 分子名称: | Mesoderm development candidate 2 | | 著者 | Chen, J, Wang, J. | | 登録日 | 2009-03-12 | | 公開日 | 2010-03-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Two Structural and Functional Domains of MESD Required for Proper Folding and Trafficking of LRP5/6.
Structure, 19, 2011
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7E34
 | | Crystal structure of SUN1-Speedy A-CDK2 | | 分子名称: | Cyclin-dependent kinase 2, GLYCEROL, SUN domain-containing protein 1, ... | | 著者 | Chen, Y, Huang, C, Wu, J, Lei, M. | | 登録日 | 2021-02-08 | | 公開日 | 2021-04-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | | 主引用文献 | The SUN1-SPDYA interaction plays an essential role in meiosis prophase I.
Nat Commun, 12, 2021
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8XBD
 | | GH18 family chitinase from cold seep metagenome | | 分子名称: | GH18 chitinase-like superfamily protein | | 著者 | Yang, J. | | 登録日 | 2023-12-06 | | 公開日 | 2023-12-27 | | 最終更新日 | 2025-04-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Exploring the role of organotrophic microbes in geochemical cycling of cold seep sediments.
Innov Geosci, 3, 2025
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2L7B
 | | NMR Structure of full length apoE3 | | 分子名称: | Apolipoprotein E | | 著者 | Chen, J, Wang, J. | | 登録日 | 2010-12-07 | | 公開日 | 2011-08-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Topology of human apolipoprotein E3 uniquely regulates its diverse biological functions.
Proc.Natl.Acad.Sci.USA, 108, 2011
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5GM4
 | | Crystal structure of FI-CMCase from Aspergillus aculeatus F-50 in complex with cellotetrose | | 分子名称: | Endoglucanase-1, SULFATE ION, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Huang, J.W, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T. | | 登録日 | 2016-07-12 | | 公開日 | 2017-05-17 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Crystal structure and genetic modifications of FI-CMCase from Aspergillus aculeatus F-50
Biochem. Biophys. Res. Commun., 478, 2016
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5GM3
 | | Crystal structure of FI-CMCase from Aspergillus aculeatus F-50 | | 分子名称: | CACODYLATE ION, Endoglucanase-1, ZINC ION | | 著者 | Huang, J.W, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T. | | 登録日 | 2016-07-12 | | 公開日 | 2017-05-17 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Crystal structure and genetic modifications of FI-CMCase from Aspergillus aculeatus F-50
Biochem. Biophys. Res. Commun., 478, 2016
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5GM9
 | | Crystal structure of a glycoside hydrolase in complex with cellobiose | | 分子名称: | Glycoside hydrolase family 45 protein, beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Gao, J, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T. | | 登録日 | 2016-07-13 | | 公開日 | 2017-04-19 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Characterization and crystal structure of a thermostable glycoside hydrolase family 45 1,4-beta-endoglucanase from Thielavia terrestris
Enzyme Microb. Technol., 99, 2017
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5H31
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2MRI
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2MR3
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2MQW
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