3QTI
| c-Met Kinase in Complex with NVP-BVU972 | 分子名称: | 6-{[6-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]methyl}quinoline, CHLORIDE ION, GLYCEROL, ... | 著者 | Appleton, B.A. | 登録日 | 2011-02-22 | 公開日 | 2011-07-06 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Drug Resistance Screen Using a Selective MET Inhibitor Reveals a Spectrum of Mutations That Partially Overlap with Activating Mutations Found in Cancer Patients. Cancer Res., 71, 2011
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3TDI
| yeast Cul1WHB-Dcn1P acetylated Ubc12N complex | 分子名称: | Defective in cullin neddylation protein 1, NEDD8-conjugating enzyme UBC12 | 著者 | Scott, D.C, Monda, J.K, Bennett, E.J, Harper, J.W, Schulman, B.A. | 登録日 | 2011-08-11 | 公開日 | 2011-10-12 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex. Science, 334, 2011
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3TDZ
| N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex: Structure of a human Cul1WHB-Dcn1P-stapled acetylated Ubc12N complex | 分子名称: | Cullin-1, DCN1-like protein 1, STAPLED PEPTIDE | 著者 | Scott, D.C, Monda, J.K, Bennett, E.J, Harper, J.W, Schulman, B.A. | 登録日 | 2011-08-11 | 公開日 | 2011-10-12 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex. Science, 334, 2011
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3T7F
| Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway | 分子名称: | Ubiquitin-like modifier-activating enzyme ATG7 | 著者 | Taherbhoy, A.M, Tait, S.W, Kaiser, S.E, Williams, A.H, Deng, A, Nourse, A, Hammel, M, Kurinov, I, Rock, C.O, Green, D.R, Schulman, B.A. | 登録日 | 2011-07-30 | 公開日 | 2011-11-23 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Atg8 transfer from atg7 to atg3: a distinctive e1-e2 architecture and mechanism in the autophagy pathway. Mol.Cell, 44, 2011
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3TEW
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3TFR
| Ternary complex structure of DNA polymerase beta with a gapped DNA substrate and a, b dAMP(CF2)PP in the active site | 分子名称: | 2'-deoxy-5'-O-[(S)-{difluoro[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}(hydroxy)phosphoryl]adenosine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*TP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | 著者 | Chamberlain, B.T, Batra, V.K, Beard, W.A, Kadina, A.P, Shock, D.D, Kashemirov, B.A, McKenna, C.E, Goodman, M.F, Wilson, S.H. | 登録日 | 2011-08-16 | 公開日 | 2012-03-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Stereospecific Formation of a Ternary Complex of (S)-alpha, beta-Fluoromethylene-dATP with DNA Pol beta. Chembiochem, 13, 2012
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3TDU
| N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex: Structure of a human Cul1WHB-Dcn1P-acetylated Ubc12N complex | 分子名称: | Cullin-1, DCN1-like protein 1, NEDD8-conjugating enzyme Ubc12 | 著者 | Scott, D.C, Monda, J.K, Bennett, E.J, Harper, J.W, Schulman, B.A. | 登録日 | 2011-08-11 | 公開日 | 2011-10-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex. Science, 334, 2011
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3TEZ
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3TEY
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3TFS
| Ternary complex structure of DNA polymerase beta with a gapped DNA substrate and a, b dAMP(CFH)PP in the active site: Stereoselective binding of (S) isomer | 分子名称: | 2'-deoxy-5'-O-[(S)-{(S)-fluoro[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}(hydroxy)phosphoryl]adenosine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*TP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | 著者 | Chamberlain, B.T, Batra, V.K, Beard, W.A, Kadina, A.P, Shock, D.D, Kashemirov, B.A, McKenna, C.E, Goodman, M.F, Wilson, S.H. | 登録日 | 2011-08-16 | 公開日 | 2012-03-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Stereospecific Formation of a Ternary Complex of (S)-alpha, beta-Fluoromethylene-dATP with DNA Pol beta. Chembiochem, 13, 2012
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3U4A
| From soil to structure: a novel dimeric family 3-beta-glucosidase isolated from compost using metagenomic analysis | 分子名称: | CALCIUM ION, JMB19063, beta-D-glucopyranose, ... | 著者 | McAndrew, R.P, Park, J.I, Reindl, W, Friedland, G.D, D'haeseleer, P, Northen, T, Sale, K.L, Simmons, B.A, Adams, P.D. | 登録日 | 2011-10-07 | 公開日 | 2013-04-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.196 Å) | 主引用文献 | From soil to structure: a novel dimeric family 3-beta--glucosidase isolated from compost using metagenomic analysis To be Published
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3U5Z
| Structure of T4 Bacteriophage clamp loader bound to the T4 clamp, primer-template DNA, and ATP analog | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ... | 著者 | Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J. | 登録日 | 2011-10-11 | 公開日 | 2012-01-04 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | How a DNA polymerase clamp loader opens a sliding clamp. Science, 334, 2011
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3TTZ
| Crystal structure of a topoisomerase ATPase inhibitor | 分子名称: | 2-[(3S,4R)-4-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}-3-fluoropiperidin-1-yl]-1,3-thiazole-5-carboxylic acid, DNA gyrase subunit B, MAGNESIUM ION | 著者 | Boriack-Sjodin, P.A, Read, J, Eakin, A.E, Sherer, B.A. | 登録日 | 2011-09-15 | 公開日 | 2011-11-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Pyrrolamide DNA gyrase inhibitors: Optimization of antibacterial activity and efficacy. Bioorg.Med.Chem.Lett., 21, 2011
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2L4K
| Water refined solution structure of the human Grb7-SH2 domain in complex with the 10 amino acid peptide pY1139 | 分子名称: | Growth factor receptor-bound protein 7, Receptor tyrosine-protein kinase erbB-2 | 著者 | Pias, S.C, Ivancic, M, Brescia, P.J, Johnson, D.L, Smith, D.E, Daly, R.J, Lyons, B.A. | 登録日 | 2010-10-07 | 公開日 | 2010-11-17 | 最終更新日 | 2012-10-03 | 実験手法 | SOLUTION NMR | 主引用文献 | Water-Refined Solution Structure of the Human Grb7-SH2 Domain in Complex with the erbB2 Receptor Peptide pY1139. Protein Pept.Lett., 19, 2012
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3TVI
| Crystal structure of Clostridium acetobutylicum aspartate kinase (CaAK): An important allosteric enzyme for industrial amino acids production | 分子名称: | ASPARTIC ACID, Aspartokinase, LYSINE | 著者 | Manjasetty, B.A, Chance, M.R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2011-09-20 | 公開日 | 2011-11-09 | 最終更新日 | 2021-02-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of Clostridium acetobutylicum Aspartate kinase (CaAK): An important allosteric enzyme for amino acids production. Biotechnol Rep (Amst), 3, 2014
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1VWB
| STREPTAVIDIN-CYCLO-AC-[CHPQFC]-NH2, PH 11.8 | 分子名称: | PEPTIDE LIGAND CONTAINING HPQ, STREPTAVIDIN | 著者 | Katz, B.A, Cass, R.T. | 登録日 | 1997-03-03 | 公開日 | 1998-03-18 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0. J.Biol.Chem., 272, 1997
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1VWA
| STREPTAVIDIN-FSHPQNT | 分子名称: | PEPTIDE LIGAND CONTAINING HPQ, STREPTAVIDIN | 著者 | Katz, B.A, Cass, R.T. | 登録日 | 1997-03-03 | 公開日 | 1998-03-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0. J.Biol.Chem., 272, 1997
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1VWJ
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1VWH
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1VWD
| STREPTAVIDIN-CYCLO-AC-[CHPQFC]-NH2, PH 3.0 | 分子名称: | PEPTIDE LIGAND CONTAINING HPQ, STREPTAVIDIN | 著者 | Katz, B.A, Cass, R.T. | 登録日 | 1997-03-03 | 公開日 | 1998-03-18 | 最終更新日 | 2011-11-16 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0. J.Biol.Chem., 272, 1997
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1VWC
| STREPTAVIDIN-CYCLO-AC-[CHPQFC]-NH2, PH 2.0 | 分子名称: | PEPTIDE LIGAND CONTAINING HPQ, STREPTAVIDIN | 著者 | Katz, B.A, Cass, R.T. | 登録日 | 1997-03-03 | 公開日 | 1998-03-18 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0. J.Biol.Chem., 272, 1997
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1VWG
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3LZ9
| The Crystal Structure of 5-epi-aristolochene synthase M4 mutant complexed with (2-trans,6-trans)-2-fluorofarnesyl diphosphate | 分子名称: | (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, Aristolochene synthase, MAGNESIUM ION | 著者 | Noel, J.P, Dellas, N, Faraldos, J.A, Zhao, M, Hess Jr, B.A, Smentek, L, Coates, R.M, O'Maille, P.E. | 登録日 | 2010-03-01 | 公開日 | 2010-04-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates. Acs Chem.Biol., 5, 2010
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3M00
| Crystal Structure of 5-epi-aristolochene synthase M4 mutant complexed with (2-cis,6-trans)-2-fluorofarnesyl diphosphate | 分子名称: | (2E,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, Aristolochene synthase, MAGNESIUM ION | 著者 | Noel, J.P, Dellas, N, Faraldos, J.A, Zhao, M, Hess Jr, B.A, Smentek, L, Coates, R.M, O'Maille, P.E. | 登録日 | 2010-03-02 | 公開日 | 2010-07-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates. Acs Chem.Biol., 5, 2010
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3M02
| The Crystal Structure of 5-epi-aristolochene synthase complexed with (2-cis,6-trans)-2-fluorofarnesyl diphosphate | 分子名称: | (2E,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, Aristolochene synthase, MAGNESIUM ION | 著者 | Noel, J.P, Dellas, N, Faraldos, J.A, Zhao, M, Hess Jr, B.A, Smentek, L, Coates, R.M, O'Maille, P.E. | 登録日 | 2010-03-02 | 公開日 | 2010-07-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates. Acs Chem.Biol., 5, 2010
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