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8J86
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Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in a DNA binding form
分子名称: CALCIUM ION, DNA (5'-D(P*AP*GP*CP*TP*GP*CP*TP*AP*TP*GP*TP*GP*AP*GP*AP*TP*TP*AP*AP*GP*TP*TP*AP*T)-3'), DNA (5'-D(P*GP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*GP*AP*TP*AP*AP*CP*TP*TP*AP*AP*TP*CP*TP*CP*AP*CP*AP*TP*AP*GP*CP*AP*GP*CP*TP*)-3'), ...
著者Xu, Y, Wu, Y, Wu, X, Zhang, Y, Yang, Y, Li, D, Yang, B, Gao, K, Zhang, Z, Dong, C.
登録日2023-04-30
公開日2024-05-01
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Structural basis of human mpox viral DNA replication inhibition by brincidofovir and cidofovir.
Int.J.Biol.Macromol., 270, 2024
8J8F
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Monkeypox virus DNA replication holoenzyme F8, A22 and E4 in complex with a DNA duplex and dCTP
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*AP*GP*CP*TP*GP*CP*TP*AP*TP*GP*AP*GP*AP*TP*TP*AP*AP*GP*TP*TP*AP*T)-3'), ...
著者Xu, Y, Wu, Y, Wu, X, Zhang, Y, Yang, Y, Li, D, Yang, B, Gao, K, Zhang, Z, Dong, C.
登録日2023-05-01
公開日2024-05-08
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Structural basis of human mpox viral DNA replication inhibition by brincidofovir and cidofovir.
Int.J.Biol.Macromol., 270, 2024
8GSB
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BU of 8gsb by Molmil
SARS-COV-2 BA.1 Spike incomplex with VacBB-665
分子名称: Light chain of VacBB-665, Spike protein S1, heavy chain of VacBB-665
著者Liu, C.C, Ju, B, Shen, S.L, Zhang, Z.
登録日2022-09-05
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (3.99 Å)
主引用文献Complex of SARS-COV-2 spike BA.1 and VacBB-665
To Be Published
8GS9
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SARS-CoV-2 BA.2 spike RBD in complex bound with VacBB-551
分子名称: Heavy chain of VacBB-551, Light chain of VacBB-551, Spike glycoprotein
著者Liu, C.C, Ju, B, Shen, S.L, Zhang, Z.
登録日2022-09-05
公開日2023-05-03
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献Omicron BQ.1.1 and XBB.1 unprecedentedly escape broadly neutralizing antibodies elicited by prototype vaccination.
Cell Rep, 42, 2023
7K0O
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BU of 7k0o by Molmil
Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 3
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0K
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa, 3KS-bound
分子名称: 3-Dehydrosphinganine, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0N
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 2
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0J
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa protomer
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0Q
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, myriocin-bound
分子名称: Myriocin, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0L
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BU of 7k0l by Molmil
Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa, myriocin-bound
分子名称: Myriocin, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0P
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BU of 7k0p by Molmil
Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 4
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0M
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BU of 7k0m by Molmil
Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 1
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0I
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BU of 7k0i by Molmil
Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
4PV7
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BU of 4pv7 by Molmil
Cocrystal structure of dipeptidyl-peptidase 4 with an indole scaffold inhibitor
分子名称: 1-[2-(2,4-dichlorophenyl)-1-(methylsulfonyl)-1H-indol-3-yl]methanamine, Dipeptidyl peptidase 4 soluble form
著者Xiao, P, Guo, R, Huang, S, Cui, H, Ye, S, Zhang, Z.
登録日2014-03-15
公開日2015-03-18
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Discovery of dipeptidyl peptidase IV (DPP4) inhibitors based on a novel indole scaffold
Chin.Chem.Lett., 25, 2014
5XRF
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BU of 5xrf by Molmil
Crystal structure of Da-36, a thrombin-like enzyme from Deinagkistrodon acutus
分子名称: DI(HYDROXYETHYL)ETHER, Snake venom serine protease Da-36, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Lin, C.-C, Wu, W.-G, Fan, Q, Tian, J, Zhang, Z, Zheng, Y.
登録日2017-06-08
公開日2018-06-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Da-36, a thrombin-like enzyme from Deinagkistrodon acutus
To Be Published
5Z09
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BU of 5z09 by Molmil
ST0452(Y97N)-UTP binding form
分子名称: Dual sugar-1-phosphate nucleotidylyltransferase, URIDINE 5'-TRIPHOSPHATE
著者Honda, Y, Nakano, S, Ito, S, Dadashipour, M, Zhang, Z, Kawarabayasi, Y.
登録日2017-12-19
公開日2018-10-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Improvement of ST0452N-Acetylglucosamine-1-Phosphate Uridyltransferase Activity by the Cooperative Effect of Two Single Mutations Identified through Structure-Based Protein Engineering
Appl. Environ. Microbiol., 84, 2018
5Z0A
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BU of 5z0a by Molmil
ST0452(Y97N)-GlcNAc binding form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Dual sugar-1-phosphate nucleotidylyltransferase
著者Honda, Y, Nakano, S, Ito, S, Dadashipour, M, Zhang, Z, Kawarabayasi, Y.
登録日2017-12-19
公開日2018-10-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Improvement of ST0452N-Acetylglucosamine-1-Phosphate Uridyltransferase Activity by the Cooperative Effect of Two Single Mutations Identified through Structure-Based Protein Engineering
Appl. Environ. Microbiol., 84, 2018
8JIN
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BU of 8jin by Molmil
The local refined map of XBB spike protein (S) in complex with bispecific antibody G7-Fc
分子名称: 7F3 Fv, GW01 Fv, Spike glycoprotein
著者Ma, Y, Mao, Q, Wang, Y, Zhang, Z.
登録日2023-05-27
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献Structure of XBB spike protein (S) di-trimer in complex with bispecific antibody G7-Fc at 3.75 Angstroms resolution.
To Be Published
8PKP
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BU of 8pkp by Molmil
Cryo-EM structure of the apo Anaphase-promoting complex/cyclosome (APC/C) at 3.2 Angstrom resolution
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D.
登録日2023-06-27
公開日2023-07-19
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1
To Be Published
8OVX
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BU of 8ovx by Molmil
Cryo-EM structure of yeast CENP-OPQU+ bound to the CENP-A N-terminus
分子名称: Inner kinetochore subunit AME1, Inner kinetochore subunit CTF19, Inner kinetochore subunit MCM21, ...
著者Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S.
登録日2023-04-26
公開日2023-08-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Sci Adv, 9, 2023
8OVW
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BU of 8ovw by Molmil
Cryo-EM structure of CBF1-CCAN bound topologically to centromeric DNA
分子名称: C0N3 DNA, Centromere-binding protein 1, Inner kinetochore subunit AME1, ...
著者Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S, Barford, D.
登録日2023-04-26
公開日2023-08-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Sci Adv, 9, 2023
8OW0
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BU of 8ow0 by Molmil
Cryo-EM structure of CBF1-CCAN bound topologically to a centromeric CENP-A nucleosome
分子名称: C0N3 DNA, Centromere-binding protein 1, Histone H2A.1, ...
著者Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S, Barford, D.
登録日2023-04-26
公開日2023-08-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Sci Adv, 9, 2023
8OW1
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BU of 8ow1 by Molmil
Cryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome.
分子名称: C0N3, Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, ...
著者Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S, Barford, D.
登録日2023-04-26
公開日2023-08-09
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Sci Adv, 9, 2023
7E8C
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BU of 7e8c by Molmil
SARS-CoV-2 S-6P in complex with 9 Fabs
分子名称: 368-2 H, 368-2 L, 604 H, ...
著者Du, S, Xiao, J, Zhang, Z.
登録日2021-03-01
公開日2021-06-09
最終更新日2021-07-14
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
7E8F
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BU of 7e8f by Molmil
SARS-CoV-2 NTD in complex with N9 Fab
分子名称: 368-2 H, 368-2 L, 604 H, ...
著者Du, S, Xiao, J, Zhang, Z.
登録日2021-03-01
公開日2021-06-09
最終更新日2021-07-14
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021

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件を2024-06-12に公開中

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