1MIU
 
 | | Structure of a BRCA2-DSS1 complex | | 分子名称: | Breast Cancer type 2 susceptibility protein, Deleted in split hand/split foot protein 1, MERCURY (II) ION | | 著者 | Yang, H, Jeffrey, P.D, Miller, J, Kinnucan, E, Sun, Y, Thoma, N.H, Zheng, N, Chen, P.L, Lee, W.H, Pavletich, N.P. | | 登録日 | 2002-08-23 | | 公開日 | 2002-09-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA
structure
Science, 297, 2002
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1MJE
 | | STRUCTURE OF A BRCA2-DSS1-SSDNA COMPLEX | | 分子名称: | 5'-D(P*TP*TP*TP*TP*TP*T)-3', Deleted in split hand/split foot protein 1, breast cancer 2 | | 著者 | Yang, H, Jeffrey, P.D, Miller, J, Kinnucan, E, Sun, Y, Thoma, N.H, Zheng, N, Chen, P.L, Lee, W.H, Pavletich, N.P. | | 登録日 | 2002-08-27 | | 公開日 | 2002-09-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.
Science, 297, 2002
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1U6G
 | | Crystal Structure of The Cand1-Cul1-Roc1 Complex | | 分子名称: | Cullin homolog 1, RING-box protein 1, TIP120 protein, ... | | 著者 | Goldenberg, S.J, Shumway, S.D, Cascio, T.C, Garbutt, K.C, Liu, J, Xiong, Y, Zheng, N. | | 登録日 | 2004-07-29 | | 公開日 | 2004-12-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases
Cell(Cambridge,Mass.), 119, 2004
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6C1P
 | | HypoPP mutant | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHAPSO, Ion transport protein, ... | | 著者 | Catterall, W.A, Zheng, N, Jiang, D, Gamal El-Din, T.M. | | 登録日 | 2018-01-05 | | 公開日 | 2018-05-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis for gating pore current in periodic paralysis.
Nature, 557, 2018
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7TE8
 | | CA14-CBD-DB21 ternary complex | | 分子名称: | CA14, DB21, cannabidiol | | 著者 | Cao, S, Zheng, N. | | 登録日 | 2022-01-04 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | | 主引用文献 | Defining molecular glues with a dual-nanobody cannabidiol sensor.
Nat Commun, 13, 2022
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7T1Y
 | | Structure of the Fbw7-Skp1-MycCdegron complex | | 分子名称: | F-box/WD repeat-containing protein 7, Myc proto-oncogene protein C terminal degron, S-phase kinase-associated protein 1, ... | | 著者 | Wang, B, Rusnac, D.V, Clurman, B.E, Zheng, N. | | 登録日 | 2021-12-02 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor.
Sci Adv, 8, 2022
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7T1Z
 | | Structure of the Fbw7-Skp1-MycNdegron complex | | 分子名称: | F-box/WD repeat-containing protein 7, Myc proto-oncogene N terminal degron, S-phase kinase-associated protein 1, ... | | 著者 | Wang, B, Rusnac, D.V, Clurman, B.E, Zheng, N. | | 登録日 | 2021-12-02 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor.
Sci Adv, 8, 2022
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7MY4
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6BRT
 | | F-box protein CTH with hydrolase | | 分子名称: | (5R)-5-hydroxy-3-methylfuran-2(5H)-one, D3-CTH-D14-D-ring | | 著者 | Shabek, N, Zheng, N, Mao, H, Hinds, T.R, Ticchiarelli, F, Leyser, O. | | 登録日 | 2017-12-01 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.393 Å) | | 主引用文献 | Structural plasticity of D3-D14 ubiquitin ligase in strigolactone signalling.
Nature, 563, 2018
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6BRQ
 | | Crystal structure of rice ASK1-D3 ubiquitin ligase complex crystal form 3 | | 分子名称: | F-box/LRR-repeat MAX2 homolog, SKP1-like protein 1A | | 著者 | Shabek, N, Zheng, N, Mao, H, Hinds, T.R, Ticchiarelli, F, Leyser, O. | | 登録日 | 2017-11-30 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Structural plasticity of D3-D14 ubiquitin ligase in strigolactone signalling.
Nature, 563, 2018
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6DSZ
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6BRP
 | | F-box protein form 2 | | 分子名称: | F-box/LRR-repeat MAX2 homolog, SKP1-like protein 1A | | 著者 | Shabek, N, Zheng, N, Mao, H, Hinds, T.R, Ticchiarelli, F, Leyser, O. | | 登録日 | 2017-11-30 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Structural plasticity of D3-D14 ubiquitin ligase in strigolactone signalling.
Nature, 563, 2018
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6BRO
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4RGW
 | | Crystal Structure of a TAF1-TAF7 Complex in Human Transcription Factor IID | | 分子名称: | GLYCEROL, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 7 | | 著者 | Wang, H, Curran, E.C, Hinds, T.R, Wang, E.H, Zheng, N. | | 登録日 | 2014-09-30 | | 公開日 | 2014-12-03 | | 最終更新日 | 2014-12-17 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module.
Cell Res., 24, 2014
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6O60
 | | Crystal structure of GGTase3-FBXL2-SKP1 complex | | 分子名称: | F-box/LRR-repeat protein 2, Geranylgeranyl transferase type-2 subunit beta, Protein prenyltransferase alpha subunit repeat-containing protein 1, ... | | 著者 | Wang, H, Zheng, N. | | 登録日 | 2019-03-04 | | 公開日 | 2019-06-26 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | | 主引用文献 | GGTase3 is a newly identified geranylgeranyltransferase targeting a ubiquitin ligase.
Nat.Struct.Mol.Biol., 26, 2019
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6C1M
 | | NavAb NormoPP mutant | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-METHYLGUANIDINE, CHAPSO, ... | | 著者 | Catterall, W.A, Zheng, N, Jiang, D, Gamal El-Din, T.M. | | 登録日 | 2018-01-04 | | 公開日 | 2018-05-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.518 Å) | | 主引用文献 | Structural basis for gating pore current in periodic paralysis.
Nature, 557, 2018
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6DO4
 | | KLHDC2 ubiquitin ligase in complex with SelS C-end degron | | 分子名称: | Kelch domain-containing protein 2, SELS C-END DEGRON | | 著者 | Rusnac, D.V, Lin, H.C, Yen, H.C.S, Zheng, N. | | 登録日 | 2018-06-08 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase.
Mol. Cell, 72, 2018
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6DO3
 | | KLHDC2 ubiquitin ligase in complex with SelK C-end degron | | 分子名称: | Kelch domain-containing protein 2, SelK C-end Degron | | 著者 | Rusnac, D.V, Lin, H.C, Yen, H.C.S, Zheng, N. | | 登録日 | 2018-06-08 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.165 Å) | | 主引用文献 | Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase.
Mol. Cell, 72, 2018
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6CHG
 | | Crystal structure of the yeast COMPASS catalytic module | | 分子名称: | H3, Histone-lysine N-methyltransferase, H3 lysine-4 specific, ... | | 著者 | Hsu, P.L, Li, H, Zheng, N. | | 登録日 | 2018-02-22 | | 公開日 | 2018-08-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.985 Å) | | 主引用文献 | Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module.
Cell, 174, 2018
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6C1K
 | | HypoPP mutant with ligand1 | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GUANIDINE, Ion transport protein, ... | | 著者 | Catterall, W.A, Zheng, N, Jiang, D, Gamal El-Din, T.M. | | 登録日 | 2018-01-04 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for gating pore current in periodic paralysis.
Nature, 557, 2018
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6C1E
 | | NavAb NormoPP mutant | | 分子名称: | (3ALPHA,5ALPHA,7ALPHA,8ALPHA,12ALPHA,14BETA,17ALPHA)-3,7,12-TRIHYDROXYCHOL-1-EN-24-AMIDE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 5-BETA-24-NOR-CHOLANE-3(ALPHA),7(ALPHA),12(ALPHA)-TRIOL, ... | | 著者 | Catterall, W.A, Zheng, N, Jiang, D, Gamal El-Din, T.M. | | 登録日 | 2018-01-04 | | 公開日 | 2018-05-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | Structural basis for gating pore current in periodic paralysis.
Nature, 557, 2018
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6DO5
 | | KLHDC2 ubiquitin ligase in complex with USP1 C-end degron | | 分子名称: | Kelch domain-containing protein 2, USP1 C-END DEGRON | | 著者 | Rusnac, D.V, Lin, H.C, Yen, H.C.S, Zheng, N. | | 登録日 | 2018-06-08 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase.
Mol. Cell, 72, 2018
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6P6W
 | | Cryo-EM structure of voltage-gated sodium channel NavAb N49K/L109A/M116V/G94C/Q150C disulfide crosslinked mutant in the resting state | | 分子名称: | Fusion of Maltose-binding protein and voltage-gated sodium channel NavAb | | 著者 | Wisedchaisri, G, Tonggu, L, McCord, E, Gamal El-Din, T.M, Wang, L, Zheng, N, Catterall, W.A. | | 登録日 | 2019-06-04 | | 公開日 | 2019-08-14 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel.
Cell, 178, 2019
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5K19
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6P6Y
 | | Crystal structure of voltage-gated sodium channel NavAb V100C/Q150C disulfide crosslinked mutant in the activated state | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein | | 著者 | Wisedchaisri, G, Tonggu, L, McCord, E, Gamal El-din, T.M, Wang, L, Zheng, N, Catterall, W.A. | | 登録日 | 2019-06-04 | | 公開日 | 2019-08-14 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel.
Cell, 178, 2019
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