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6MNL
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BU of 6mnl by Molmil
NMR solution structures of second bromodomain of BRD4 with FOXO3a peptide
分子名称: Bromodomain-containing protein 4, FOXO3a peptide
著者Zeng, L, Zhou, M.-M.
登録日2018-10-02
公開日2018-10-31
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer.
Nat Commun, 9, 2018
2D82
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BU of 2d82 by Molmil
Target Structure-Based Discovery of Small Molecules that Block Human p53 and CREB Binding Protein (CBP) Association
分子名称: 9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE, CREB-binding protein
著者Sachchidanand, Resnick-Silverman, L, Yan, S, Mujtaba, S, Liu, W.J, Zeng, L, Manfredi, J.J, Zhou, M.M.
登録日2005-12-01
公開日2006-04-04
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Target structure-based discovery of small molecules that block human p53 and CREB binding protein association
Chem.Biol., 13, 2006
1XR0
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BU of 1xr0 by Molmil
Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors
分子名称: Basic fibroblast growth factor receptor 1, FGFR signalling adaptor SNT-1
著者Dhalluin, C, Yan, K.S, Plotnikova, O, Lee, K.W, Zeng, L, Kuti, M, Mujtaba, S, Goldfarb, M.P, Zhou, M.-M.
登録日2004-10-13
公開日2004-11-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors
Mol.Cell, 6, 2000
1JM4
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BU of 1jm4 by Molmil
NMR Structure of P/CAF Bromodomain in Complex with HIV-1 Tat Peptide
分子名称: HIV-1 Tat Peptide, P300/CBP-associated Factor
著者Mujtaba, S, He, Y, Zeng, L, Farooq, A, Carlson, J.E, Ott, M, Verdin, E, Zhou, M.-M.
登録日2001-07-17
公開日2002-07-17
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain
Mol.Cell, 9, 2002
2AQE
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BU of 2aqe by Molmil
Structural and functional analysis of ada2 alpha swirm domain
分子名称: Transcriptional adaptor 2, Ada2 alpha
著者Qian, C, Zhang, Q, Zeng, L, Zhou, M.-M.
登録日2005-08-17
公開日2005-12-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and chromosomal DNA binding of the SWIRM domain
Nat.Struct.Mol.Biol., 12, 2005
2AQF
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BU of 2aqf by Molmil
Structural and functional analysis of ADA2 alpha swirm domain
分子名称: transcriptional adaptor 2, Ada2 alpha
著者Qian, C, Zhang, Q, Zhou, M.-M, Zeng, L.
登録日2005-08-17
公開日2006-01-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and chromosomal DNA binding of the SWIRM domain.
Nat.Struct.Mol.Biol., 12, 2005
8TUX
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BU of 8tux by Molmil
Capsid of mature PP7 virion with 3'end region of PP7 genomic RNA
分子名称: 3'end of PP7 genomic RNA, Capsid protein, Maturation protein A
著者Thongchol, J, Zhang, J, Zeng, L.
登録日2023-08-17
公開日2024-03-13
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Removal of Pseudomonas type IV pili by a small RNA virus.
Science, 384, 2024
8TUW
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BU of 8tuw by Molmil
Type IV pilus from Pseudomonas PAO1 strain with PP7 Maturation protein
分子名称: Maturation protein A, Type IV major pilin protein PilA
著者Thongchol, J, Zhang, J, Zeng, L.
登録日2023-08-17
公開日2024-03-13
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Removal of Pseudomonas type IV pili by a small RNA virus.
Science, 384, 2024
8TUM
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BU of 8tum by Molmil
Type IV pilus from Pseudomonas PAO1 strain
分子名称: Type IV major pilin protein PilA
著者Thongchol, J, Zhang, J, Zeng, L.
登録日2023-08-16
公開日2024-03-13
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Removal of Pseudomonas type IV pili by a small RNA virus.
Science, 384, 2024
1OY2
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BU of 1oy2 by Molmil
Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc
分子名称: SHC transforming protein
著者Farooq, A, Zeng, L, Yan, K.S, Ravichandran, K.S, Zhou, M.-M.
登録日2003-04-03
公開日2004-04-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc
Structure, 11, 2003
1OP4
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BU of 1op4 by Molmil
Solution Structure of Neural Cadherin Prodomain
分子名称: Neural-cadherin
著者Koch, A.W, Farooq, A, Shan, W, Zeng, L, Colman, D.R, Zhou, M.-M.
登録日2003-03-04
公開日2004-03-16
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Structure of the Neural (N-) Cadherin Prodomain Reveals a Cadherin Extracellular Domain-like Fold without Adhesive Characteristics
Structure, 12, 2004
1R4K
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BU of 1r4k by Molmil
Solution Structure of the Drosophila Argonaute 1 PAZ Domain
分子名称: Argonaute 1
著者Yan, K.S, Yan, S, Farooq, A, Han, A, Zeng, L, Zhou, M.-M.
登録日2003-10-07
公開日2003-12-09
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and conserved RNA binding of the PAZ domain
Nature, 426, 2003
1SZV
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BU of 1szv by Molmil
Structure of the Adaptor Protein p14 reveals a Profilin-like Fold with Novel Function
分子名称: Late endosomal/lysosomal Mp1 interacting protein
著者Qian, C, Zhang, Q, Wang, X, Zeng, L, Farooq, A, Zhou, M.M.
登録日2004-04-06
公開日2005-03-15
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the Adaptor Protein p14 Reveals a Profilin-like Fold with Distinct Function
J.Mol.Biol., 347, 2005
1JSP
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BU of 1jsp by Molmil
NMR Structure of CBP Bromodomain in complex with p53 peptide
分子名称: CREB-BINDING PROTEIN, tumor protein p53
著者He, Y, Mujtaba, S, Zeng, L, Yan, S, Zhou, M.-M.
登録日2001-08-17
公開日2002-08-17
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation.
Mol.Cell, 13, 2004
1N3H
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BU of 1n3h by Molmil
Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc
分子名称: SHC Transforming protein
著者Farooq, A, Zeng, L, Yan, K.S, Ravichandran, K.S, Zhou, M.-M.
登録日2002-10-28
公開日2003-10-28
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc
Structure, 11, 2003
1N3J
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BU of 1n3j by Molmil
Structure and Substrate of a Histone H3 Lysine Methyltransferase from Paramecium Bursaria Chlorella Virus 1
分子名称: Histone H3 Lysine Methyltransferase
著者Manzur, K.L, Farooq, A, Zeng, L, Plotnikova, O, Sachchidanand, Koch, A.W, Zhou, M.-M.
登録日2002-10-28
公開日2003-01-28
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A dimeric viral SET domain methyltransferase specific to Lys27 of histone H3.
Nat.Struct.Biol., 10, 2003
1N72
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BU of 1n72 by Molmil
Structure and Ligand of a Histone Acetyltransferase Bromodomain
分子名称: HISTONE ACETYLTRANSFERASE
著者Dhalluin, C, Carlson, J.E, Zeng, L, He, C, Aggarwal, A.K, Zhou, M.-M.
登録日2002-11-12
公開日2002-12-11
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and Ligand of a Histone Acetyltransferase Bromodomain
Nature, 399, 1999
7XFG
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BU of 7xfg by Molmil
NMR solution structures of p300 TAZ2 domain in complex with BRD4-NUT F1c domain binding motif #1
分子名称: Histone acetyltransferase p300, NUT family member 1, ZINC ION
著者Yu, D, Zeng, L, Zhou, M.-M.
登録日2022-04-01
公開日2023-04-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Mechanism of BRD4-NUT Fusion Protein in p300-Activated Hyperacetylation
To Be Published
7XEZ
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BU of 7xez by Molmil
NMR solution structures of p300 TAZ2 domain in complex with BRD4-NUT F1c domain binding motif #2
分子名称: Histone acetyltransferase p300,NUT family member 1, ZINC ION
著者Yu, D, Zeng, L, Zhou, M.-M.
登録日2022-03-31
公開日2023-04-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Mechanism of BRD4-NUT Fusion Protein in p300-Activated Hyperacetylation
To Be Published
7Y0I
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BU of 7y0i by Molmil
Solution structures of ASH1L PHD domain in complex with H3K4me2 peptide
分子名称: ALA-ARG-THR-MLY-GLN-THR-ALA-ARG-LYS-SER-THR-GLY-GLY-LYS-ALA, Histone-lysine N-methyltransferase ASH1L, ZINC ION
著者Yu, M, Zeng, L.
登録日2022-06-05
公開日2022-10-12
実験手法SOLUTION NMR
主引用文献Structural insight into ASH1L PHD finger recognizing methylated histone H3K4 and promoting cell growth in prostate cancer.
Front Oncol, 12, 2022
3LJW
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BU of 3ljw by Molmil
Crystal Structure of the Second Bromodomain of Human Polybromo
分子名称: ACETATE ION, Protein polybromo-1, SODIUM ION
著者Charlop-Powers, Z, Zhou, M.M, Zeng, L, Zhang, Q.
登録日2010-01-26
公開日2010-05-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献Structural insights into selective histone H3 recognition by the human Polybromo bromodomain 2.
Cell Res., 20, 2010
6BNH
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BU of 6bnh by Molmil
Solution NMR structures of BRD4 ET domain with JMJD6 peptide
分子名称: Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, Bromodomain-containing protein 4
著者Konuma, T, Yu, D, Zhao, C, Ju, Y, Sharma, R, Ren, C, Zhang, Q, Zhou, M.-M, Zeng, L.
登録日2017-11-16
公開日2017-12-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4.
Sci Rep, 7, 2017
4PVG
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BU of 4pvg by Molmil
Crystal structure of protein tyrosine phosphatase Shp2 catalytic domain complex with small molecular compound L88N79
分子名称: 2-[3-({4-[(1,3-benzodioxol-5-ylmethyl)amino]-4-oxobutanoyl}amino)phenyl]-6-hydroxy-3-iodo-1-methyl-1H-indole-5-carboxylic acid, Tyrosine-protein phosphatase non-receptor type 11
著者Zhang, Z.-Y, Zeng, L, Liu, D, Yu, Z.
登録日2014-03-17
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of protein tyrosine Shp2 catalytic domain complex with compound L88N79
To be Published
4LGB
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BU of 4lgb by Molmil
ABA-mimicking ligand N-(1-METHYL-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-6-YL)-1-(4-METHYLPHENYL)METHANESULFONAMIDE in complex with ABA receptor PYL2 and PP2C HAB1
分子名称: Abscisic acid receptor PYL2, MAGNESIUM ION, N-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-1-(4-methylphenyl)methanesulfonamide, ...
著者Zhou, X.E, Gao, M, Liu, X, Zhang, Y, Xue, X, Melcher, K, Gao, P, Wang, F, Zeng, L, Zhao, Y, Zhao, Y, Deng, P, Zhong, D, Zhu, J.-K, Xu, Y, Xu, H.E.
登録日2013-06-27
公開日2013-08-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献An ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants.
Cell Res., 23, 2013
4LG5
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ABA-mimicking ligand QUINABACTIN in complex with ABA receptor PYL2 and PP2C HAB1
分子名称: Abscisic acid receptor PYL2, MAGNESIUM ION, Protein phosphatase 2C 16, ...
著者Zhou, X.E, Gao, M, Liu, X, Zhang, Y, Xue, X, Melcher, K, Gao, P, Wang, F, Zeng, L, Zhao, Y, Zhao, Y, Deng, P, Zhong, D, Zhu, J.-K, Xu, Y, Xu, H.E.
登録日2013-06-27
公開日2013-08-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献An ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants.
Cell Res., 23, 2013

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