4PVG

Crystal structure of protein tyrosine phosphatase Shp2 catalytic domain complex with small molecular compound L88N79

Summary for 4PVG

• Entry DOI: 10.2210/pdb4pvg/pdb
• Descriptor: Tyrosine-protein phosphatase non-receptor type 11, 2-[3-({4-[(1,3-benzodioxol-5-ylmethyl)amino]-4-oxobutanoyl}amino)phenyl]-6-hydroxy-3-iodo-1-methyl-1H-indole-5-carboxylic acid (3 entities in total)
• Functional Keywords: hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q06124
• Total number of polymer chains: 1
• Total formula weight: 35619.10

Authors

Zhang, Z.-Y.,Zeng, L.,Liu, D.,Yu, Z. (deposition date: 2014-03-17, release date: 2015-04-15, Last modification date: 2023-09-20)

• Primary citation: Zhang, Z.-Y.,Zeng, L.,Liu, D.,Yu, Z.; Crystal structure of protein tyrosine Shp2 catalytic domain complex with compound L88N79; To be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)