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6DDM
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Crystal Structure Analysis of the Epitope of an Anti-MICA Antibody
分子名称: Anti-MICA Fab fragment heavy chain clone 1D5, Anti-MICA Fab fragment light chain clone 1D5, MHC class I polypeptide-related sequence A
著者Matsumoto, M.L.
登録日2018-05-10
公開日2018-10-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies.
MAbs, 11, 2019
6DDV
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BU of 6ddv by Molmil
Crystal Structure Analysis of the Epitope of an Anti-MICA Antibody
分子名称: Anti-MICA Fab fragment heavy chain clone 6E1, Anti-MICA Fab fragment light chain clone 6E1, MHC class I chain-related protein A
著者Matsumoto, M.L.
登録日2018-05-10
公開日2018-10-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies.
MAbs, 11, 2019
3QOD
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BU of 3qod by Molmil
Crystal Structure of Heterocyst Differentiation Protein, HetR from Fischerella mv11
分子名称: Heterocyst differentiation protein
著者Kim, Y, Joachimiak, G, Gornicki, P, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2011-02-09
公開日2011-04-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.38 Å)
主引用文献Structure of transcription factor HetR required for heterocyst differentiation in cyanobacteria.
Proc.Natl.Acad.Sci.USA, 108, 2011
3QOE
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BU of 3qoe by Molmil
Crystal Structure of Heterocyst Differentiation Protein, HetR from Fischerella mv11
分子名称: Heterocyst differentiation protein
著者Kim, Y, Joachimiak, G, Gornicki, P, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2011-02-09
公開日2011-04-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.004 Å)
主引用文献Structure of transcription factor HetR required for heterocyst differentiation in cyanobacteria.
Proc.Natl.Acad.Sci.USA, 108, 2011
5YU9
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BU of 5yu9 by Molmil
Crystal structure of EGFR 696-1022 T790M in complex with Ibrutinib
分子名称: 1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one, CHLORIDE ION, Epidermal growth factor receptor
著者Yan, X.E, Yun, C.H.
登録日2017-11-21
公開日2017-12-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation.
Oncotarget, 7, 2016
4J01
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BU of 4j01 by Molmil
Crystal Structure of Fischerella Transcription Factor HetR complexed with 29mer DNA target
分子名称: DNA (29-MER), SULFATE ION, Transcription Factor HetR
著者Kim, Y, Joachimiak, G, Gornicki, P, Joachimiak, A, MCSG, Midwest Center for Structural Genomics (MCSG)
登録日2013-01-30
公開日2013-03-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.246 Å)
主引用文献Structures of complexes comprised of Fischerella transcription factor HetR with Anabaena DNA targets.
Proc.Natl.Acad.Sci.USA, 110, 2013
4IZZ
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BU of 4izz by Molmil
Crystal Structure of Fischerella Transcription Factor HetR complexed with 21mer DNA target
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*TP*GP*AP*GP*GP*GP*GP*TP*TP*AP*AP*AP*CP*CP*CP*CP*TP*CP*AP*C)-3'), SULFATE ION, ...
著者Kim, Y, Joachimiak, G, Gornicki, P, Joachimiak, A, MCSG, Midwest Center for Structural Genomics (MCSG)
登録日2013-01-30
公開日2013-03-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Structures of complexes comprised of Fischerella transcription factor HetR with Anabaena DNA targets.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J00
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Crystal Structure of Fischerella Transcription Factor HetR complexed with 24mer DNA target
分子名称: DNA (5'-D(*TP*GP*GP*TP*GP*AP*GP*GP*GP*GP*TP*TP*AP*AP*AP*CP*CP*CP*CP*TP*CP*AP*CP*C)-3'), MAGNESIUM ION, Transcription Factor HetR
著者Kim, Y, Joachimiak, G, Gornicki, P, Joachimiak, A, MCSG, Midwest Center for Structural Genomics (MCSG)
登録日2013-01-30
公開日2013-03-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.004 Å)
主引用文献Structures of complexes comprised of Fischerella transcription factor HetR with Anabaena DNA targets.
Proc.Natl.Acad.Sci.USA, 110, 2013
1XHN
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The crystal structure of Cellular Repressor of E1A-stimulated Genes (CREG)
分子名称: Cellular Repressor of E1A-stimulated Genes
著者Sacher, M, Lunin, V.V, Cygler, M.
登録日2004-09-20
公開日2005-11-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The crystal structure of CREG, a secreted glycoprotein involved in cellular growth and differentiation
Proc.Natl.Acad.Sci.Usa, 102, 2005
8K60
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BU of 8k60 by Molmil
Cryo-EM structure of Streptomyces coelicolor transcription initiation complex with the global transcription factor AfsR
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Lin, W, Shi, J.
登録日2023-07-24
公開日2024-07-31
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights into transcription activation of the Streptomyces antibiotic regulatory protein, AfsR
Iscience, 27, 2024
8GXF
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Pseudomonas flexibilis GCN5 family acetyltransferase
分子名称: COENZYME A, GCN5 family acetyltransferase
著者Song, Y.J, Bao, R.
登録日2022-09-20
公開日2022-10-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献The novel type II toxin-antitoxin PacTA modulates Pseudomonas aeruginosa iron homeostasis by obstructing the DNA-binding activity of Fur.
Nucleic Acids Res., 50, 2022
8GXJ
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Pseudomonas aeruginosa N-acetyltransferase domain-containing protein PA3270
分子名称: N-acetyltransferase domain-containing protein
著者Song, Y.J, Bao, R.
登録日2022-09-20
公開日2022-10-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献The novel type II toxin-antitoxin PacTA modulates Pseudomonas aeruginosa iron homeostasis by obstructing the DNA-binding activity of Fur.
Nucleic Acids Res., 50, 2022
8GXK
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BU of 8gxk by Molmil
Pseudomonas jinjuensis N-acetyltransferase
分子名称: COENZYME A, Protein N-acetyltransferase, RimJ/RimL family
著者Song, Y.J, Bao, R.
登録日2022-09-20
公開日2022-10-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献The novel type II toxin-antitoxin PacTA modulates Pseudomonas aeruginosa iron homeostasis by obstructing the DNA-binding activity of Fur.
Nucleic Acids Res., 50, 2022
8IP0
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BU of 8ip0 by Molmil
Cryo-EM structure of type I-B Cascade bound to a PAM-containing dsDNA target at 3.6 angstrom resolution
分子名称: CRISPR associated protein Cas11b, DNA (41-MER), DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ...
著者Xiao, Y, Lu, M, Yu, C, Zhang, Y.
登録日2023-03-13
公開日2024-03-20
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure and genome editing of type I-B CRISPR-Cas.
Nat Commun, 15, 2024
8H67
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BU of 8h67 by Molmil
type I-B Cascade bound to a PAM-containing dsDNA target at 3.8 angstrom resolution.
分子名称: CRISPR RNA, CRISPR associated protein Cas11b, CRISPR associated protein Cas5, ...
著者Xiao, Y, Lu, M, Yu, C, Zhang, Y.
登録日2022-10-15
公開日2024-05-01
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure and genome editing of type I-B CRISPR-Cas.
Nat Commun, 15, 2024
1O77
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BU of 1o77 by Molmil
CRYSTAL STRUCTURE OF THE C713S MUTANT OF THE TIR DOMAIN OF HUMAN TLR2
分子名称: TOLL-LIKE RECEPTOR 2
著者Tao, X, Xu, Y, Ye, Z, Beg, A.A, Tong, L.
登録日2002-10-24
公開日2002-11-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献An Extensively Associated Dimer in the Structure of the C713S Mutant of the Tir Domain of Human Tlr2
Biochem.Biophys.Res.Commun., 299, 2002
7BPB
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BU of 7bpb by Molmil
Human AAA+ ATPase VCP mutant - T76E, AMP-PNP bound form, Conformation I
分子名称: ADENOSINE-5'-DIPHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Yang, C, Zhang, H.
登録日2020-03-22
公開日2021-03-31
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle.
Cell Death Differ., 2022
7BP9
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BU of 7bp9 by Molmil
Human AAA+ ATPase VCP mutant - T76E, ADP-bound form
分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
著者Yang, C, Zhang, H.
登録日2020-03-21
公開日2021-03-31
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle.
Cell Death Differ., 2022
7BP8
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BU of 7bp8 by Molmil
Human AAA+ ATPase VCP mutant - T76A, ADP-bound form
分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
著者Yang, C, Zhang, H.
登録日2020-03-21
公開日2021-03-31
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle.
Cell Death Differ., 2022
7BPA
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BU of 7bpa by Molmil
Human AAA+ ATPase VCP mutant - T76A, AMP-PNP-bound form, Conformation I
分子名称: ADENOSINE-5'-DIPHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Yang, C, Zhang, H.
登録日2020-03-21
公開日2021-03-31
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle.
Cell Death Differ., 2022
8Y6U
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BU of 8y6u by Molmil
Cryo-EM structure of E.coli transcription initiation complex with transcription factor GcvA
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Lin, W, Shi, J.
登録日2024-02-03
公開日2024-06-05
実験手法ELECTRON MICROSCOPY (3.97 Å)
主引用文献NMR analysis of a loop-bulge structure of UUCGA pentaloop.
Biochem.Biophys.Res.Commun., 691, 2024
8U31
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Crystal structure of PD-1 in complex with a Fab
分子名称: Fab heavy chain, Fab light chain, GLYCEROL, ...
著者Sun, D, Masureel, M.
登録日2023-09-07
公開日2024-06-19
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability.
Mabs, 16, 2024
8U32
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Crystal structure of PD-1 in complex with a Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ...
著者Sun, D, Masureel, M.
登録日2023-09-07
公開日2024-06-19
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability.
Mabs, 16, 2024
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件を2024-08-07に公開中

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