2HT4
 
 | | Structure of the Escherichia coli ClC chloride channel Y445W mutant and Fab complex | | 分子名称: | BROMIDE ION, Fab fragment, Heavy chain, ... | | 著者 | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | 登録日 | 2006-07-25 | | 公開日 | 2006-09-19 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
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3DET
 | | Structure of the E148A, Y445A doubly ungated mutant of E.coli CLC_Ec1, Cl-/H+ antiporter | | 分子名称: | Fab fragment, Heavy chain, Light chain, ... | | 著者 | Jayaram, H, Accardi, A, Wu, F, Williams, C, Miller, C. | | 登録日 | 2008-06-10 | | 公開日 | 2008-06-17 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger
Proc.Natl.Acad.Sci.USA, 105, 2008
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5LO4
 | | Engineering protein stability with atomic precision in a monomeric miniprotein | | 分子名称: | PPa-CH3 | | 著者 | Baker, E.G, Williams, C, Hudson, K.L, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N. | | 登録日 | 2016-08-08 | | 公開日 | 2017-05-17 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Engineering protein stability with atomic precision in a monomeric miniprotein.
Nat. Chem. Biol., 13, 2017
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7OUB
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5LO2
 | | Engineering protein stability with atomic precision in a monomeric miniprotein | | 分子名称: | PPaTyr | | 著者 | Baker, E.G, Hudson, K.L, Williams, C, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N. | | 登録日 | 2016-08-08 | | 公開日 | 2017-05-17 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Engineering protein stability with atomic precision in a monomeric miniprotein.
Nat. Chem. Biol., 13, 2017
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5LO3
 | | Engineering protein stability with atomic precision in a monomeric miniprotein | | 分子名称: | PPaOMe | | 著者 | Baker, E.G, Hudson, K.L, Williams, C, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N. | | 登録日 | 2016-08-08 | | 公開日 | 2017-05-17 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Engineering protein stability with atomic precision in a monomeric miniprotein.
Nat. Chem. Biol., 13, 2017
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3ND0
 | | X-ray crystal structure of a slow cyanobacterial Cl-/H+ antiporter | | 分子名称: | CHLORIDE ION, Sll0855 protein | | 著者 | Jayaram, H, Robertson, J, Wu, F, Williams, C, Miller, C. | | 登録日 | 2010-06-06 | | 公開日 | 2011-01-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure of a Slow CLC Cl(-)/H(+) Antiporter from a Cyanobacterium.
Biochemistry, 50, 2011
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3NCY
 | | X-ray crystal structure of an arginine agmatine antiporter (AdiC) in complex with a Fab fragment | | 分子名称: | AdiC, Fab Heavy chain, Fab Light chain | | 著者 | Fang, Y, Jayaram, H, Shane, T, Komalkova-Partensky, L, Wu, F, Williams, C, Xiong, Y, Miller, C. | | 登録日 | 2010-06-06 | | 公開日 | 2010-08-18 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure of a prokaryotic virtual proton pump at 3.2 A resolution.
Nature, 460, 2009
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4I8A
 | | Alanine-glyoxylate aminotransferase variant S187F | | 分子名称: | GLYCEROL, Serine-pyruvate aminotransferase | | 著者 | Fodor, K, Oppici, E, Williams, C, Cellini, B, Wilmanns, M. | | 登録日 | 2012-12-03 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of the S187F variant of human liver alanine: Aminotransferase associated with primary hyperoxaluria type I and its functional implications.
Proteins, 81, 2013
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8OJR
 | | Solution NMR Structure of Alpha-Synuclein 1-25 Peptide in 50% TFE. | | 分子名称: | Alpha-synuclein | | 著者 | Allen, S.G, Williams, C, Meade, R.M, Tang, T.M.S, Crump, M.P, Mason, J.M. | | 登録日 | 2023-03-24 | | 公開日 | 2023-08-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | An N-terminal alpha-Synuclein fragment binds lipid vesicles to modulate lipid induced aggregation
Cell Rep Phys Sci, 2023
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8OL8
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5IEI
 | | X-ray crystallographic structure of a high affinity IGF2 antagonist (Domain11 AB5 RHH) based on human IGF2R domain 11 | | 分子名称: | 1,2-ETHANEDIOL, Cation-independent mannose-6-phosphate receptor, GLYCEROL, ... | | 著者 | Nicholls, R.D, Williams, C, Strickland, M, Frago, S, Hassan, A.B, Crump, M.P. | | 登録日 | 2016-02-25 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist.
Proc.Natl.Acad.Sci.USA, 113, 2016
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6GWX
 | | Stabilising and Understanding a Miniprotein by Rational Design. | | 分子名称: | Optimised PPa-TYR | | 著者 | Porter Goff, K.L, Williams, C, Baker, E.G, Nicol, D, Samphire, J.L, Zieleniewski, F.L, Crump, M.P, Woolfson, D.N. | | 登録日 | 2018-06-26 | | 公開日 | 2019-07-10 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Stabilizing and Understanding a Miniprotein by Rational Redesign.
Biochemistry, 58, 2019
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6Z30
 | | Human cation-independent mannose 6-phosphate/ IGF2 receptor domains 9-10 | | 分子名称: | Cation-independent mannose-6-phosphate receptor, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Bochel, A.J, Williams, C, Crump, M.P. | | 登録日 | 2020-05-19 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7-11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9.
Structure, 28, 2020
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5NKZ
 | | Crystal structure of H. polymorpha ubiquitin conjugating enzyme Pex4p in complex with soluble domain of Pex22p | | 分子名称: | Peroxin 22, Ubiquitin-conjugating enzyme E2-21 kDa | | 著者 | Danda, N, Lunev, S, Ali, A, Groves, M.R, Williams, C. | | 登録日 | 2017-04-03 | | 公開日 | 2018-01-24 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex.
Biochem. Biophys. Res. Commun., 496, 2018
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6Z31
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6Z32
 | | Human cation-independent mannose 6-phosphate/IGF2 receptor domains 7-11 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cation-independent mannose-6-phosphate receptor, SULFATE ION, ... | | 著者 | Bochel, A.J, Williams, C, McCoy, A.J, Hoppe, H, Winter, A.J, Nicholls, R.D, Harlos, K, Jones, Y.E, Berger, I, Hassan, B, Crump, M.P. | | 登録日 | 2020-05-19 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.47 Å) | | 主引用文献 | Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7-11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9.
Structure, 28, 2020
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1Q1J
 | | Crystal Structure Analysis of anti-HIV-1 Fab 447-52D in complex with V3 peptide | | 分子名称: | Fab 447-52D, heavy chain, light chain, ... | | 著者 | Stanfield, R.L, Gorny, M.K, Williams, C, Zolla-Pazner, S, Wilson, I.A. | | 登録日 | 2003-07-21 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural rationale for the broad neutralization of HIV-1 by human monoclonal antibody 447-52D.
Structure, 12, 2004
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2K0X
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5NL8
 | | Pex4 of Hansenula Polymorpha | | 分子名称: | Ubiquitin-conjugating enzyme E2-21 kDa | | 著者 | Groves, M, Williams, C. | | 登録日 | 2017-04-04 | | 公開日 | 2018-01-24 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex.
Biochem. Biophys. Res. Commun., 496, 2018
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6G1N
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6G26
 | | The crystal structure of the Burkholderia pseudomallei HicAB complex | | 分子名称: | 1,2-ETHANEDIOL, HicA, HicB, ... | | 著者 | Winter, A.J, Isupov, M.N, Williams, C, Crump, M.P. | | 登録日 | 2018-03-22 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | The molecular basis of protein toxin HicA-dependent binding of the protein antitoxin HicB to DNA.
J. Biol. Chem., 293, 2018
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6FXD
 | | Crystal structure of MupZ from Pseudomonas fluorescens | | 分子名称: | MupZ | | 著者 | Wang, L, Parnell, A, Williams, C, Bakar, N.A, van der Kamp, M.W, Simpson, T.J, Race, P.R, Crump, M.P, Willis, C.L. | | 登録日 | 2018-03-08 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | A Rieske oxygenase/epoxide hydrolase-catalysed reaction cascade creates oxygen heterocycles in mupirocin biosynthesis
Nat Catal, 2018
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6G1C
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2CNR
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