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4F02
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Crystal structure of the PABP-binding site of eIF4G in complex with RRM1-2 of PABP and poly(A)
分子名称: Eukaryotic translation initiation factor 4 gamma 1, Polyadenylate-binding protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')
著者Safaee, N, Kozlov, G, Gehring, K.B.
登録日2012-05-03
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.
Mol.Cell, 48, 2012
4F26
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Crystal structure of the second RRM domain of human PABPC1 a pH 9.0
分子名称: Polyadenylate-binding protein 1
著者Kozlov, G, Safaee, N, Gehring, K.
登録日2012-05-07
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.
Mol.Cell, 48, 2012
4F25
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BU of 4f25 by Molmil
Crystal structure of the second RRM domain of human PABPC1 at pH 6.0
分子名称: Polyadenylate-binding protein 1
著者Kozlov, G, Safaee, N, Gehring, K.
登録日2012-05-07
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.
Mol.Cell, 48, 2012
5DQG
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BU of 5dqg by Molmil
Crystal Structure of Human DNA Polymerase Eta Inserting dAMPNPP Opposite O4-Ethylthymidine
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(5EJ)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
著者Patra, A, OFlaherty, D.K, Egli, M.
登録日2015-09-14
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta.
Chem Sci, 7, 2016
5DLG
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BU of 5dlg by Molmil
Crystal Structure of Human DNA Polymerase Eta Inserting dGMPNPP Opposite O4-Methylhymidine
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(5DB)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
著者Patra, A, OFlaherty, D.K, Egli, M.
登録日2015-09-04
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.351 Å)
主引用文献Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta.
Chem Sci, 7, 2016
5DQH
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BU of 5dqh by Molmil
Crystal Structure of Human DNA Polymerase Eta Inserting dGMPNPP Opposite O4-Ethylthymidine
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(5EJ)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
著者Patra, A, OFlaherty, D.K, Egli, M.
登録日2015-09-14
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta.
Chem Sci, 7, 2016
5DLF
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BU of 5dlf by Molmil
Crystal Structure of Human DNA Polymerase Eta Inserting dATP Opposite O4-Methylhymidine
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
著者Patra, A, OFlaherty, D.K, Egli, M.
登録日2015-09-04
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta.
Chem Sci, 7, 2016
7SOT
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BU of 7sot by Molmil
LaM domain of human LARP1 in complex with AAAAAA oligonucleotide
分子名称: Isoform 2 of La-related protein 1, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3'), SULFATE ION
著者Kozlov, G, Gehring, K.
登録日2021-11-01
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOV
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BU of 7sov by Molmil
LaM domain of human LARP1 in complex with AAAAAAAAAAA RNA polynucleotide
分子名称: GLYCEROL, Isoform 2 of La-related protein 1, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ...
著者Kozlov, G, Gehring, K.
登録日2021-11-01
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOO
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LaM domain of human LARP1
分子名称: Isoform 2 of La-related protein 1, SODIUM ION, SULFATE ION
著者Kozlov, G, Gehring, K.
登録日2021-11-01
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOQ
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BU of 7soq by Molmil
LaM domain of human LARP1 in complex with AAA RNA
分子名称: Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*A)-3')
著者Kozlov, G, Gehring, K.
登録日2021-11-01
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOP
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BU of 7sop by Molmil
LaM domain of human LARP1 in complex with AAAUAA RNA
分子名称: Isoform 2 of La-related protein 1, RNA (5'-R(P*AP*AP*AP*UP*AP*A)-3')
著者Kozlov, G, Gehring, K.
登録日2021-11-01
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOR
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BU of 7sor by Molmil
LaM domain of human LARP1 in complex with AAA RNA
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Isoform 2 of La-related protein 1, ...
著者Kozlov, G, Gehring, K.
登録日2021-11-01
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOU
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BU of 7sou by Molmil
LaM domain of human LARP1 in complex with AAAAAA polynucleotide
分子名称: Isoform 2 of La-related protein 1, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3')
著者Kozlov, G, Gehring, K.
登録日2021-11-01
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOS
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BU of 7sos by Molmil
LaM domain of human LARP1 in complex with AAAA RNA
分子名称: Isoform 2 of La-related protein 1, POTASSIUM ION, RNA (5'-R(*AP*AP*AP*A)-3')
著者Kozlov, G, Gehring, K.
登録日2021-11-01
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
5TGG
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BU of 5tgg by Molmil
Solution structure of parallel stranded adenosine duplex
分子名称: RNA/DNA (5'-D(P*T)-R(*(A2M)P*(A2M)P*(A2M)P*(A2M))-D(P*A)-R(P*(A2M)P*(A2M)P*(A2M))-3')
著者Denisov, A, Noronha, A, Gehring, K, Wilds, C.
登録日2016-09-27
公開日2017-08-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Influence of nucleotide modifications at the C2' position on the Hoogsteen base-paired parallel-stranded duplex of poly(A) RNA.
Nucleic Acids Res., 45, 2017
5DQI
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BU of 5dqi by Molmil
Crystal Structure of Human DNA Polymerase Eta Extending an O4-Ethylthymidine : dA Pair By Inserting dCTP Opposite dG
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*AP*C)-3'), ...
著者Patra, A, OFlaherty, D.K, Egli, M.
登録日2015-09-14
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta.
Chem Sci, 7, 2016
2H9S
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BU of 2h9s by Molmil
Crystal Structure of Homo-DNA and Nature's Choice of Pentose over Hexose in the Genetic System
分子名称: 5'-D(*(XCT)P*(XGU)P*(XAD)P*(XAD)P*(XTH)P*(XTH)P*(XCT)P*(XGU))-3', MAGNESIUM ION
著者Egli, M, Pallan, P.S.
登録日2006-06-11
公開日2006-12-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of homo-DNA and nature's choice of pentose over hexose in the genetic system.
J.Am.Chem.Soc., 128, 2006
1HO6
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BU of 1ho6 by Molmil
CHIMERIC ARABINONUCLEIC ACID (ANA) HAIRPIN WITH ANA/RNA HYBRID STEM
分子名称: DNA/RNA (5'-R(*GP*GP*AP*C)-D(P*TP*TP*CP*G)-(P*(GAO)P*(UAR)P*(CAR)P*(CAR)-3')
著者Denisov, A.Y, Gehring, K.
登録日2000-12-08
公開日2001-11-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of an arabinonucleic acid (ANA)/RNA duplex in a chimeric hairpin: comparison with 2'-fluoro-ANA/RNA and DNA/RNA hybrids.
Nucleic Acids Res., 29, 2001
1HOQ
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BU of 1hoq by Molmil
CHIMERIC RNA/DNA HAIRPIN
分子名称: DNA/RNA (5'-R(*GP*GP*AP*C)-D(P*TP*TP*CP*GP*GP*TP*CP*C)-3')
著者Denisov, A.Y, Gehring, K.
登録日2000-12-11
公開日2001-11-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of an arabinonucleic acid (ANA)/RNA duplex in a chimeric hairpin: comparison with 2'-fluoro-ANA/RNA and DNA/RNA hybrids.
Nucleic Acids Res., 29, 2001
2LSC
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BU of 2lsc by Molmil
Solution structure of 2'F-ANA and ANA self-complementary duplex
分子名称: DNA (5'-D(*(CFL)P*(GFL)P*(CFL)P*(GFL)P*(A5O)P*(A5O)P*(UAR)P*(UAR)P*(CFL)P*(GFL)P*(CFL)P*(GFL))-3')
著者Martin-Pintado, N, Yahyaee, M, Campos, R, Noronha, A, Wilds, C, Damha, M, Gonzalez, C.
登録日2012-04-26
公開日2012-07-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The solution structure of double helical arabino nucleic acids (ANA and 2'F-ANA): effect of arabinoses in duplex-hairpin interconversion.
Nucleic Acids Res., 40, 2012
5VXQ
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BU of 5vxq by Molmil
X-Ray crystallography structure of the parallel stranded duplex formed by 5-rA5-dA-rA5
分子名称: AMMONIUM ION, DNA/RNA (5'-R(*AP*AP*AP*AP*A)-D(P*A)-R(P*AP*AP*AP*AP*A)-3')
著者Xie, J, Chen, Y, Wei, X, Kozlov, G, Gehring, K.
登録日2017-05-23
公開日2017-08-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.002 Å)
主引用文献Influence of nucleotide modifications at the C2' position on the Hoogsteen base-paired parallel-stranded duplex of poly(A) RNA.
Nucleic Acids Res., 45, 2017
2GUN
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BU of 2gun by Molmil
RNA-Binding Affinities and Crystal Structure of Oligonucleotides containing Five-Atom Amide-Based Backbone Structures
分子名称: 5'-D(*TP*TP*CP*(T2T)P*(CBR)P*TP*TP*C)-3', 5'-R(*GP*AP*AP*GP*AP*AP*GP*AP*A)-3', COBALT (III) ION, ...
著者Pallan, P.S, Egli, M.
登録日2006-05-01
公開日2006-08-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献RNA-Binding Affinities and Crystal Structure of Oligonucleotides Containing Five-Atom Amide-Based Backbone Structures.
Biochemistry, 45, 2006
2FIH
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BU of 2fih by Molmil
Crystal Structure Analysis of the B-DNA Dodecamer CGCGAA-aU-TCGCG, with Incorporated Arabino-Uridine (aU)
分子名称: 5'-D(*CP*GP*CP*GP*AP*AP*(UAR)P*TP*CP*GP*CP*G)-3', MAGNESIUM ION
著者Egli, M, Li, F.
登録日2005-12-29
公開日2006-05-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.
Biochemistry, 45, 2006
2FII
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Crystal Structure Analysis of the B-DNA Dodecamer CGCGAAT-aU-CGCG, with Incorporated Arabino-Uridin (aU)
分子名称: 5'-D(*CP*GP*CP*GP*AP*AP*TP*(UAR)P*CP*GP*CP*G)-3', MAGNESIUM ION
著者Egli, M, Li, F.
登録日2005-12-29
公開日2006-05-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.
Biochemistry, 45, 2006

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件を2024-09-04に公開中

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