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Structure of human RyR2-S2808D in the closed state in the presence of ARM210
分子名称:	4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者	Miotto, M.C, Marks, A.R.
登録日	2023-10-23
公開日	2023-11-15
最終更新日	2024-10-02
実験手法	ELECTRON MICROSCOPY (3.18 Å)
主引用文献	Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024

8UQ4

Structure of human RyR2-S2808D in the subprimed state in the presence of H2O2/NOC-12/GSH
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者	Miotto, M.C, Marks, A.R.
登録日	2023-10-23
公開日	2023-11-15
最終更新日	2024-10-02
実験手法	ELECTRON MICROSCOPY (3.64 Å)
主引用文献	Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024

8UQ5

Structure of human RyR2-S2808D in the primed state in the presence of Rapamycin
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, Ryanodine receptor 2, ZINC ION
著者	Miotto, M.C, Marks, A.R.
登録日	2023-10-23
公開日	2023-11-15
最終更新日	2024-10-02
実験手法	ELECTRON MICROSCOPY (3.96 Å)
主引用文献	Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024

8UXE

Structure of PKA phosphorylated human RyR2-R420Q in the closed state in the presence of ARM210
分子名称:	4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者	Miotto, M.C, Marks, A.R.
登録日	2023-11-09
公開日	2023-11-22
最終更新日	2024-10-02
実験手法	ELECTRON MICROSCOPY (3.53 Å)
主引用文献	Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024

8UXC

Structure of PKA phosphorylated human RyR2-R420Q in the primed state
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者	Miotto, M.C, Marks, A.R.
登録日	2023-11-09
公開日	2023-11-22
最終更新日	2024-10-02
実験手法	ELECTRON MICROSCOPY (2.86 Å)
主引用文献	Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024

8UXG

Structure of PKA phosphorylated human RyR2-R420W in the closed state in the presence of ARM210
分子名称:	4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者	Miotto, M.C, Marks, A.R.
登録日	2023-11-09
公開日	2023-11-22
最終更新日	2024-10-02
実験手法	ELECTRON MICROSCOPY (3.08 Å)
主引用文献	Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024

8UXH

Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者	Miotto, M.C, Marks, A.R.
登録日	2023-11-09
公開日	2023-11-22
最終更新日	2024-10-02
実験手法	ELECTRON MICROSCOPY (3.52 Å)
主引用文献	Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024

8UXF

Structure of PKA phosphorylated human RyR2-R420W in the primed state
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者	Miotto, M.C, Marks, A.R.
登録日	2023-11-09
公開日	2023-11-22
最終更新日	2024-10-02
実験手法	ELECTRON MICROSCOPY (3.13 Å)
主引用文献	Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024

8UXL

Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium and calmodulin
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
著者	Miotto, M.C, Marks, A.R.
登録日	2023-11-09
公開日	2023-11-22
最終更新日	2024-10-02
実験手法	ELECTRON MICROSCOPY (3.12 Å)
主引用文献	Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024

8UXI

Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者	Miotto, M.C, Marks, A.R.
登録日	2023-11-09
公開日	2023-11-22
最終更新日	2024-10-02
実験手法	ELECTRON MICROSCOPY (3.29 Å)
主引用文献	Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024

8UXM

Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium and calmodulin
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
著者	Miotto, M.C, Marks, A.R.
登録日	2023-11-09
公開日	2023-11-22
最終更新日	2024-10-02
実験手法	ELECTRON MICROSCOPY (3.56 Å)
主引用文献	Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024

1KXA

SINDBIS VIRUS CAPSID, (WILD-TYPE) RESIDUES 106-264, TETRAGONAL CRYSTAL FORM
分子名称:	SINDBIS VIRUS CAPSID PROTEIN
著者	Choi, H.-K, Rossmann, M.G.
登録日	1996-05-05
公開日	1996-11-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (3.1 Å)
主引用文献	Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. J.Mol.Biol., 262, 1996

1KXF

SINDBIS VIRUS CAPSID, (WILD-TYPE) RESIDUES 1-264, TETRAGONAL CRYSTAL FORM (FORM II)
分子名称:	SINDBIS VIRUS CAPSID PROTEIN
著者	Choi, H.-K, Rossmann, M.G.
登録日	1996-05-05
公開日	1996-12-07
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.38 Å)
主引用文献	Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. J.Mol.Biol., 262, 1996

1KXC

SINDBIS VIRUS CAPSID (N190K MUTANT), TETRAGONAL CRYSTAL FORM
分子名称:	SINDBIS VIRUS CAPSID PROTEIN
著者	Choi, H.-K, Rossmann, M.G.
登録日	1996-05-05
公開日	1996-11-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (3.1 Å)
主引用文献	Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. J.Mol.Biol., 262, 1996

1KXD

SINDBIS VIRUS CAPSID (N222L MUTANT), TETRAGONAL CRYSTAL FORM
分子名称:	SINDBIS VIRUS CAPSID PROTEIN
著者	Choi, H.-K, Rossmann, M.G.
登録日	1996-05-05
公開日	1996-11-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. J.Mol.Biol., 262, 1996

1KXB

SINDBIS VIRUS CAPSID (S215A MUTANT), TETRAGONAL CRYSTAL FORM
分子名称:	SINDBIS VIRUS CAPSID PROTEIN
著者	Choi, H.-K, Rossmann, M.G.
登録日	1996-05-05
公開日	1996-11-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. J.Mol.Biol., 262, 1996

1KXE

SINDBIS VIRUS CAPSID (Y180S, E183G DOUBLE MUTANT), TETRAGONAL CRYSTAL FORM
分子名称:	SINDBIS VIRUS CAPSID PROTEIN
著者	Choi, H.-K, Rossmann, M.G.
登録日	1996-05-05
公開日	1996-11-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (3.2 Å)
主引用文献	Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. J.Mol.Biol., 262, 1996

2SNV

THE REFINED STRUCTURE OF SINDBIS VIRUS CORE PROTEIN IN COMPARISON WITH OTHER CHYMOTRYPSIN-LIKE SERINE PROTEINASE STRUCTURES
分子名称:	SINDBIS VIRUS COAT PROTEIN
著者	Tong, L, Rossmann, M.G.
登録日	1992-07-17
公開日	1993-10-31
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Refined structure of Sindbis virus core protein and comparison with other chymotrypsin-like serine proteinase structures. J.Mol.Biol., 230, 1993

4XWK

P-glycoprotein co-crystallized with BDE-100
分子名称:	2,4-dibromophenyl 2,4,6-tribromophenyl ether, Multidrug resistance protein 1A
著者	McGrath, A.P, Rees, S.D, Chang, G.
登録日	2015-01-28
公開日	2016-04-27
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (3.5 Å)
主引用文献	Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure. Sci Adv, 2, 2016

7UA4

Structure of PKA phosphorylated human RyR2-R2474S in the open state in the presence of Calmodulin
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
著者	Miotto, M.C, Marks, A.R.
登録日	2022-03-11
公開日	2022-08-03
実験手法	ELECTRON MICROSCOPY (2.93 Å)
主引用文献	Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Sci Adv, 8, 2022

7U9R

Structure of PKA phosphorylated human RyR2 in the open state
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者	Miotto, M.C, Marks, A.R.
登録日	2022-03-11
公開日	2022-08-03
実験手法	ELECTRON MICROSCOPY (3.69 Å)
主引用文献	Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Sci Adv, 8, 2022

7UA5

Structure of dephosphorylated human RyR2 in the closed state
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者	Miotto, M.C, Marks, A.R.
登録日	2022-03-11
公開日	2022-08-03
実験手法	ELECTRON MICROSCOPY (2.83 Å)
主引用文献	Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Sci Adv, 8, 2022

7U9Z

Structure of PKA phosphorylated human RyR2-R2474S in the open state
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者	Miotto, M.C, Marks, A.R.
登録日	2022-03-11
公開日	2022-08-03
最終更新日	2024-10-09
実験手法	ELECTRON MICROSCOPY (3.29 Å)
主引用文献	Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Sci Adv, 8, 2022

7U9Q

Structure of PKA phosphorylated human RyR2 in the closed state
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者	Miotto, M.C, Marks, A.R.
登録日	2022-03-11
公開日	2022-08-03
実験手法	ELECTRON MICROSCOPY (3.11 Å)
主引用文献	Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Sci Adv, 8, 2022

7U9X

Structure of PKA phosphorylated human RyR2-R2474S in the closed state
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者	Miotto, M.C, Marks, A.R.
登録日	2022-03-11
公開日	2022-08-03
最終更新日	2024-10-09
実験手法	ELECTRON MICROSCOPY (2.58 Å)
主引用文献	Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Sci Adv, 8, 2022

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