8UXF

Structure of PKA phosphorylated human RyR2-R420W in the primed state

This is a non-PDB format compatible entry.

Summary for 8UXF

• Entry DOI: 10.2210/pdb8uxf/pdb
• EMDB information: 42762
• Descriptor: Ryanodine receptor 2, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... (4 entities in total)
• Functional Keywords: calcium channel, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 2312773.59

Authors

Miotto, M.C.,Marks, A.R. (deposition date: 2023-11-09, release date: 2023-11-22)

• Primary citation: Miotto, M.C.; Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.13 Å)