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8UQ5

Structure of human RyR2-S2808D in the primed state in the presence of Rapamycin

This is a non-PDB format compatible entry.
Summary for 8UQ5
Entry DOI10.2210/pdb8uq5/pdb
EMDB information42461
DescriptorRyanodine receptor 2, ZINC ION, ADENOSINE-5'-TRIPHOSPHATE (3 entities in total)
Functional Keywordscalcium channel, membrane protein
Biological sourceHomo sapiens (human)
Total number of polymer chains4
Total formula weight2265575.58
Authors
Miotto, M.C.,Marks, A.R. (deposition date: 2023-10-23, release date: 2023-11-15)
Primary citationMiotto, M.C.
Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.96 Å)
Structure validation

218853

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