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8UQ5

Structure of human RyR2-S2808D in the primed state in the presence of Rapamycin

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Ryanodine receptor 2polymer4967565314.14UniProt (Q92736)
Pfam (PF08709)
Pfam (PF01365)
Pfam (PF02026)
Pfam (PF08454)
Pfam (PF06459)
Pfam (PF00520)
Pfam (PF02815)
Pfam (PF00622)
Pfam (PF21119)
Homo sapiens (human)
2E, H, K, N
(A, B, C, D)
ZINC IONnon-polymer65.44Chemie (ZN)
3F, G, I, J, L...
(A, B, C, D)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.28Chemie (ATP)
Sequence modifications
A, B, C, D: 1 - 4967 (UniProt: Q92736)
PDBExternal DatabaseDetails
Asp 2808Ser 2808engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight2261256.5
Non-Polymers*Number of molecules12
Total formula weight4319.1
All*Total formula weight2265575.6
*Water molecules are not included.

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PDB entries from 2025-07-02

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