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Structure of citryl-CoA lyase from Hydrogenobacter thermophilus
分子名称:	COENZYME A, Citryl-CoA lyase, SULFATE ION
著者	Verstraete, K, Verschueren, K.
登録日	2018-10-17
公開日	2019-04-10
最終更新日	2024-05-01
実験手法	X-RAY DIFFRACTION (1.45 Å)
主引用文献	Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019

6HXN

Structure of the citryl-CoA lyase core module of Chlorobium limicola ATP citrate lyase (space group P3121)
分子名称:	ATP-citrate lyase alpha-subunit, COENZYME A, SULFATE ION
著者	Verstraete, K, Verschueren, K.
登録日	2018-10-17
公開日	2019-04-10
最終更新日	2024-05-01
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019

6HXL

Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH (space group P21)
分子名称:	1,2-ETHANEDIOL, ATP-citrate synthase, CITRATE ANION, ...
著者	Verstraete, K, Verschueren, K.
登録日	2018-10-17
公開日	2019-04-10
最終更新日	2024-05-01
実験手法	X-RAY DIFFRACTION (1.35 Å)
主引用文献	Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019

6HXQ

Structure of citryl-CoA synthetase from Hydrogenobacter thermophilus
分子名称:	CITRATE ANION, COENZYME A, Citryl-CoA synthetase large subunit, ...
著者	Verstraete, K, Verschueren, K.
登録日	2018-10-17
公開日	2019-04-10
最終更新日	2024-01-24
実験手法	X-RAY DIFFRACTION (2.91 Å)
主引用文献	Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019

6HXK

Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate
分子名称:	1,2-ETHANEDIOL, ATP-citrate synthase, CITRATE ANION, ...
著者	Verstraete, K, Verschueren, K.
登録日	2018-10-17
公開日	2019-04-10
最終更新日	2024-05-01
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019

6HXM

Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH in space group C2221
分子名称:	ATP-citrate synthase, CITRATE ANION, COENZYME A
著者	Verstraete, K, Verschueren, K.
登録日	2018-10-17
公開日	2019-04-10
最終更新日	2024-05-01
実験手法	X-RAY DIFFRACTION (1.3 Å)
主引用文献	Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019

1AL3

COFACTOR BINDING FRAGMENT OF CYSB FROM KLEBSIELLA AEROGENES
分子名称:	CYS REGULON TRANSCRIPTIONAL ACTIVATOR CYSB, SULFATE ION
著者	Verschueren, K.H.G, Tyrrell, R, Wilkinson, A.J.
登録日	1997-06-10
公開日	1997-12-24
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	The structure of the cofactor-binding fragment of the LysR family member, CysB: a familiar fold with a surprising subunit arrangement. Structure, 5, 1997

1EDD

CRYSTALLOGRAPHIC AND FLUORESCENCE STUDIES OF THE INTERACTION OF HALOALKANE DEHALOGENASE WITH HALIDE IONS: STUDIES WITH HALIDE COMPOUNDS REVEAL A HALIDE BINDING SITE IN THE ACTIVE SITE
分子名称:	CHLORIDE ION, HALOALKANE DEHALOGENASE
著者	Verschueren, K.H.G, Dijkstra, B.W.
登録日	1993-05-13
公開日	1993-10-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.19 Å)
主引用文献	Crystallographic and fluorescence studies of the interaction of haloalkane dehalogenase with halide ions. Studies with halide compounds reveal a halide binding site in the active site. Biochemistry, 32, 1993

1EDE

REFINED X-RAY STRUCTURES OF HALOALKANE DEHALOGENASE AT PH 6.2 AND PH 8.2 AND IMPLICATIONS FOR THE REACTION MECHANISM
分子名称:	HALOALKANE DEHALOGENASE
著者	Verschueren, K.H.G, Dijkstra, B.W.
登録日	1993-05-13
公開日	1993-10-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Refined X-ray structures of haloalkane dehalogenase at pH 6.2 and pH 8.2 and implications for the reaction mechanism. J.Mol.Biol., 232, 1993

1EDB

CRYSTALLOGRAPHIC AND FLUORESCENCE STUDIES OF THE INTERACTION OF HALOALKANE DEHALOGENASE WITH HALIDE IONS: STUDIES WITH HALIDE COMPOUNDS REVEAL A HALIDE BINDING SITE IN THE ACTIVE SITE
分子名称:	CHLORIDE ION, HALOALKANE DEHALOGENASE
著者	Verschueren, K.H.G, Dijkstra, B.W.
登録日	1993-05-13
公開日	1993-10-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.01 Å)
主引用文献	Crystallographic and fluorescence studies of the interaction of haloalkane dehalogenase with halide ions. Studies with halide compounds reveal a halide binding site in the active site. Biochemistry, 32, 1993

2DHE

CRYSTALLOGRAPHIC ANALYSIS OF THE CATALYTIC MECHANISM OF HALOALKANE DEHALOGENASE
分子名称:	CHLORIDE ION, HALOALKANE DEHALOGENASE
著者	Verschueren, K.H.G, Dijkstra, B.W.
登録日	1993-06-24
公開日	1994-08-31
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.13 Å)
主引用文献	Crystallographic analysis of the catalytic mechanism of haloalkane dehalogenase. Nature, 363, 1993

2DHD

CRYSTALLOGRAPHIC ANALYSIS OF THE CATALYTIC MECHANISM OF HALOALKANE DEHALOGENASE
分子名称:	CHLORIDE ION, HALOALKANE DEHALOGENASE
著者	Verschueren, K.H.G, Dijkstra, B.W.
登録日	1993-09-08
公開日	1994-07-31
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (2.13 Å)
主引用文献	Crystallographic analysis of the catalytic mechanism of haloalkane dehalogenase. Nature, 363, 1993

2DHC

CRYSTALLOGRAPHIC ANALYSIS OF THE CATALYTIC MECHANISM OF HALOALKANE DEHALOGENASE
分子名称:	1,2-DICHLOROETHANE, HALOALKANE DEHALOGENASE
著者	Verschueren, K.H.G, Dijkstra, B.W.
登録日	1993-09-08
公開日	1994-07-31
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Crystallographic analysis of the catalytic mechanism of haloalkane dehalogenase. Nature, 363, 1993

2EDC

CRYSTALLOGRAPHIC AND FLUORESCENCE STUDIES OF THE INTERACTION OF HALOALKANE DEHALOGENASE WITH HALIDE IONS: STUDIES WITH HALIDE COMPOUNDS REVEAL A HALIDE BINDING SITE IN THE ACTIVE SITE
分子名称:	HALOALKANE DEHALOGENASE, IODIDE ION
著者	Verschueren, K.H.G, Dijkstra, B.W.
登録日	1993-08-31
公開日	1994-01-31
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Crystallographic and fluorescence studies of the interaction of haloalkane dehalogenase with halide ions. Studies with halide compounds reveal a halide binding site in the active site. Biochemistry, 32, 1993

2EDA

CRYSTALLOGRAPHIC AND FLUORESCENCE STUDIES OF THE INTERACTION OF HALOALKANE DEHALOGENASE WITH HALIDE IONS: STUDIES WITH HALIDE COMPOUNDS REVEAL A HALIDE BINDING SITE IN THE ACTIVE SITE
分子名称:	HALOALKANE DEHALOGENASE, IODIDE ION
著者	Verschueren, K.H.G, Dijkstra, B.W.
登録日	1993-08-30
公開日	1993-10-31
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.19 Å)
主引用文献	Crystallographic and fluorescence studies of the interaction of haloalkane dehalogenase with halide ions. Studies with halide compounds reveal a halide binding site in the active site. Biochemistry, 32, 1993

7S5B

Unbound State of a De novo designed Protein Binder to the Human Interleukin-7 Receptor
分子名称:	Miniprotein Binder
著者	Walsh, S.T.R, Cao, L, Baker, D.
登録日	2021-09-10
公開日	2022-05-11
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (1.5 Å)
主引用文献	Design of protein-binding proteins from the target structure alone. Nature, 605, 2022

7RDH

Crystal structure of the de novo designed binding protein H3mb in complex with the 1968 influenza A virus hemagglutinin
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, De novo designed protein H3mb, ...
著者	Kadam, R.U, Wilson, I.A.
登録日	2021-07-09
公開日	2022-05-04
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.75 Å)
主引用文献	Design of protein-binding proteins from the target structure alone. Nature, 605, 2022

7Z3P

Crystal structure of the mouse leptin:LepR-CRH2 encounter complex to 1.95 A resolution.
分子名称:	CALCIUM ION, DI(HYDROXYETHYL)ETHER, Leptin, ...
著者	Tsirigotaki, A, Verschueren, K, Savvides, S.N, Verstraete, K.
登録日	2022-03-02
公開日	2023-03-22
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.943 Å)
主引用文献	Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023

7Z3R

Crystal structure of the mouse leptin:LepR-IgCRH2 complex to 2.95 A resolution.
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor
著者	Verstraete, K, Verschueren, K, Savvides, S.N, Tsirigotaki, A.
登録日	2022-03-02
公開日	2023-03-22
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.951 Å)
主引用文献	Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023

7Z3Q

Crystal structure of the human leptin:LepR-CRH2 encounter complex to 3.6 A resolution.
分子名称:	Leptin, Leptin receptor
著者	Verstraete, K, Verschueren, K, Alexandra, T, Savvides, S.N.
登録日	2022-03-02
公開日	2023-03-22
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (3.617 Å)
主引用文献	Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023

7N1J

Crystal structure of FGFR4 domain 3 in complex with a de novo-designed mini-binder
分子名称:	Binder, Fibroblast growth factor receptor 4
著者	Park, J.S, Lee, S.
登録日	2021-05-27
公開日	2022-04-06
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.99 Å)
主引用文献	Design of protein-binding proteins from the target structure alone. Nature, 605, 2022

7N1K

Crystal structure of a de novo-designed mini-protein targeting FGFR
分子名称:	Binder
著者	Park, J.S, Lee, S.
登録日	2021-05-27
公開日	2022-04-06
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (3.01 Å)
主引用文献	Design of protein-binding proteins from the target structure alone. Nature, 605, 2022

7N3T

TrkA ECD complex with designed miniprotein ligand
分子名称:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Jude, K.M, Cao, L, Garcia, K.C.
登録日	2021-06-01
公開日	2022-04-20
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (1.84 Å)
主引用文献	Design of protein-binding proteins from the target structure alone. Nature, 605, 2022

6GLX

Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 4E8
分子名称:	Fab 4E8 - Heavy chain, Fab 4E8 - Light chain, Galectin-10
著者	Verstraete, K, Verschueren, K, Savvides, S.N.
登録日	2018-05-23
公開日	2019-06-05
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (3.396 Å)
主引用文献	Protein crystallization promotes type 2 immunity and is reversible by antibody treatment. Science, 364, 2019

6GKU

Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 6F5
分子名称:	CALCIUM ION, Fab 6F5 - Heavy Chain, Fab 6F5 - Light chain, ...
著者	Verstraete, K, Verschueren, K, Savvides, S.N.
登録日	2018-05-21
公開日	2019-06-05
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (1.91 Å)
主引用文献	Protein crystallization promotes type 2 immunity and is reversible by antibody treatment. Science, 364, 2019

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