5NQ3
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![BU of 5nq3 by Molmil](/molmil-images/mine/5nq3) | 'Porcine (Sus scrofa) Major Histocompatibility Complex, class I, with human beta2 micro globulin, presenting EFEDLTFLA | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLU-PHE-GLU-ASP-LEU-THR-PHE-LEU-ALA, ... | 著者 | Rizkallah, P.J, Tungatt, K, Sewell, A.K. | 登録日 | 2017-04-19 | 公開日 | 2018-04-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig. Plos Pathog., 14, 2018
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5NPZ
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![BU of 5npz by Molmil](/molmil-images/mine/5npz) | Porcine (Sus scrofa) Major Histocompatibility Complex, class I, presenting EFEDLTFLA | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | 著者 | Rizkallah, P.J, Tungatt, K, Sewell, A.K. | 登録日 | 2017-04-19 | 公開日 | 2018-05-02 | 最終更新日 | 2019-05-15 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig. Plos Pathog., 14, 2018
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5NQ1
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![BU of 5nq1 by Molmil](/molmil-images/mine/5nq1) | Porcine (Sus scrofa) Major Histocompatibility Complex, class I, with human beta2 micro globulin, presenting DFEREGYSL | 分子名称: | 1,2-ETHANEDIOL, ASP-PHE-GLU-ARG-GLU-GLY-TYR-SER-LEU, Beta-2-microglobulin, ... | 著者 | Rizkallah, P.J, Tungatt, K, Sewell, A.K. | 登録日 | 2017-04-19 | 公開日 | 2018-04-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig. Plos Pathog., 14, 2018
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2QP2
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![BU of 2qp2 by Molmil](/molmil-images/mine/2qp2) | Structure of a MACPF/perforin-like protein | 分子名称: | CALCIUM ION, Unknown protein | 著者 | Rosado, C.J, Buckle, A.M, Law, R.H.P, Butcher, R.E, Kan, W.T, Bird, C.H, Ung, K, Browne, K.A, Baran, K, Bashtannyk-Puhalovich, T.A, Faux, N.G, Wong, W, Porter, C.J, Pike, R.N, Ellisdon, A.M, Pearce, M.C, Bottomley, S.P, Emsley, J, Smith, A.I, Rossjohn, J, Hartland, E.L, Voskoboinik, I, Trapani, J.A, Bird, P.I, Dunstone, M.A, Whisstock, J.C. | 登録日 | 2007-07-22 | 公開日 | 2007-09-04 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A common fold mediates vertebrate defense and bacterial attack Science, 317, 2007
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6R7Q
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![BU of 6r7q by Molmil](/molmil-images/mine/6r7q) | Structure of XBP1u-paused ribosome nascent chain complex with Sec61. | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Shanmuganathan, V, Cheng, J, Braunger, K, Berninghausen, O, Beatrix, B, Beckmann, R. | 登録日 | 2019-03-29 | 公開日 | 2019-07-10 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural and mutational analysis of the ribosome-arresting human XBP1u. Elife, 8, 2019
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6R6G
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![BU of 6r6g by Molmil](/molmil-images/mine/6r6g) | Structure of XBP1u-paused ribosome nascent chain complex with SRP. | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Shanmuganathan, V, Cheng, J, Braunger, K, Berninghausen, O, Beatrix, B, Beckmann, R. | 登録日 | 2019-03-27 | 公開日 | 2019-07-10 | 最終更新日 | 2019-10-30 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural and mutational analysis of the ribosome-arresting human XBP1u. Elife, 8, 2019
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6DF1
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![BU of 6df1 by Molmil](/molmil-images/mine/6df1) | |
6DEZ
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![BU of 6dez by Molmil](/molmil-images/mine/6dez) | |
6DF0
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![BU of 6df0 by Molmil](/molmil-images/mine/6df0) | |
6DF2
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![BU of 6df2 by Molmil](/molmil-images/mine/6df2) | |
8T2R
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![BU of 8t2r by Molmil](/molmil-images/mine/8t2r) | Structure of a group II intron ribonucleoprotein in the pre-ligation (pre-2F) state | 分子名称: | 5'exon, AMMONIUM ION, CALCIUM ION, ... | 著者 | Xu, L, Liu, T, Chung, K, Pyle, A.M. | 登録日 | 2023-06-06 | 公開日 | 2023-11-22 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into intron catalysis and dynamics during splicing. Nature, 624, 2023
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8T2T
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![BU of 8t2t by Molmil](/molmil-images/mine/8t2t) | Structure of a group II intron ribonucleoprotein in the post-ligation (post-2F) state | 分子名称: | AMMONIUM ION, Group II intron reverse transcriptase/maturase, MAGNESIUM ION, ... | 著者 | Xu, L, Liu, T, Chung, K, Pyle, A.M. | 登録日 | 2023-06-06 | 公開日 | 2023-11-22 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into intron catalysis and dynamics during splicing. Nature, 624, 2023
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8T2S
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![BU of 8t2s by Molmil](/molmil-images/mine/8t2s) | Structure of a group II intron ribonucleoprotein in the pre-branching (pre-1F) state | 分子名称: | AMMONIUM ION, CALCIUM ION, Group II intron reverse transcriptase/maturase, ... | 著者 | Xu, L, Liu, T, Chung, K, Pyle, A.M. | 登録日 | 2023-06-06 | 公開日 | 2023-11-22 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into intron catalysis and dynamics during splicing. Nature, 624, 2023
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6E74
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![BU of 6e74 by Molmil](/molmil-images/mine/6e74) | Structure of Human Transthyretin Leu55Pro Mutant in Complex with Tafamidis | 分子名称: | 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin | 著者 | Saelices, L, Chung, K, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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6E76
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![BU of 6e76 by Molmil](/molmil-images/mine/6e76) | Structure of Human Transthyretin Asp38Ala/Thr119Met Mutant | 分子名称: | ACETATE ION, GLYCEROL, SULFATE ION, ... | 著者 | Saelices, L, Chung, K, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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6E71
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![BU of 6e71 by Molmil](/molmil-images/mine/6e71) | Structure of Human Transthyretin Val30Met/Thr119Met Mutant | 分子名称: | DI(HYDROXYETHYL)ETHER, Transthyretin | 著者 | Saelices, L, Chung, K, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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6E77
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![BU of 6e77 by Molmil](/molmil-images/mine/6e77) | Structure of Human Transthyretin Asp38Ala Mutant in Complex with Tafamidis | 分子名称: | 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin | 著者 | Saelices, L, Chung, K, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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4AUA
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![BU of 4aua by Molmil](/molmil-images/mine/4aua) | Liganded X-ray crystal structure of cyclin dependent kinase 6 (CDK6) | 分子名称: | 1H-benzimidazol-2-yl(1H-pyrrol-2-yl)methanone, CYCLIN-DEPENDENT KINASE 6 | 著者 | Cho, Y.S, Angove, H, Brain, C, Chen, C.H.T, Cheng, R, Chopra, R, Chung, K, Congreve, M, Dagostin, C, Davis, D, Feltell, R, Giraldes, J, Hiscock, S, Kim, S, Kovats, S, Lagu, B, Lewry, K, Loo, A, Lu, Y, Luzzio, M, Maniara, W, Mcmenamin, R, Mortenson, P, Benning, R, O'Reilly, M, Rees, D, Shen, J, Smith, T, Wang, Y, Williams, G, Woolford, A, Wrona, W, Xu, M, Yang, F, Howard, S. | 登録日 | 2012-05-15 | 公開日 | 2013-02-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Fragment-Based Discovery of 7-Azabenzimidazoles as Potent, Highly Selective, and Orally Active CDK4/6 Inhibitors. ACS Med Chem Lett, 3, 2012
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5MC6
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![BU of 5mc6 by Molmil](/molmil-images/mine/5mc6) | Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Schmidt, C, Kowalinski, E, Shanmuganathan, V, Defenouillere, Q, Braunger, K, Heuer, A, Pech, M, Namane, A, Berninghausen, O, Fromont-Racine, M, Jacquier, A, Conti, E, Becker, T, Beckmann, R. | 登録日 | 2016-11-09 | 公開日 | 2017-01-18 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex. Science, 354, 2016
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5EBB
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![BU of 5ebb by Molmil](/molmil-images/mine/5ebb) | Structure of human sphingomyelinase phosphodiesterase like 3A (SMPDL3A) with Zn2+ | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3a, GLYCEROL, ... | 著者 | Lim, S.M, Yeung, K, Tresaugues, L, Teo, H.L, Nordlund, P. | 登録日 | 2015-10-19 | 公開日 | 2016-01-20 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The structure and catalytic mechanism of human sphingomyelin phosphodiesterase like 3a - an acid sphingomyelinase homologue with a novel nucleotide hydrolase activity. Febs J., 283, 2016
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5EBE
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![BU of 5ebe by Molmil](/molmil-images/mine/5ebe) | Structure of human sphingomyelinase phosphodiesterase like 3A (SMPDL3A) with 5' CMP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-O-phosphono-beta-D-ribofuranose, ... | 著者 | Lim, S.M, Yeung, K, Tresaugues, L, Teo, H.L, Nordlund, P. | 登録日 | 2015-10-19 | 公開日 | 2016-01-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The structure and catalytic mechanism of human sphingomyelin phosphodiesterase like 3a - an acid sphingomyelinase homologue with a novel nucleotide hydrolase activity. Febs J., 283, 2016
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4M8I
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![BU of 4m8i by Molmil](/molmil-images/mine/4m8i) | 1.43 Angstrom resolution crystal structure of cell division protein FtsZ (ftsZ) from Staphylococcus epidermidis RP62A in complex with GDP | 分子名称: | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION | 著者 | Halavaty, A.S, Minasov, G, Winsor, J, Dubrovska, I, Filippova, E.V, Olsen, D.B, Therien, A, Shuvalova, L, Young, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2013-08-13 | 公開日 | 2013-09-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | 1.43 Angstrom resolution crystal structure of cell division protein FtsZ (ftsZ) from Staphylococcus epidermidis RP62A in complex with GDP To be Published
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4ZZN
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![BU of 4zzn by Molmil](/molmil-images/mine/4zzn) | Human ERK2 in complex with an inhibitor | 分子名称: | 2-[[5-chloranyl-2-(oxan-4-ylamino)pyridin-4-yl]amino]-N-methyl-benzamide, MITOGEN-ACTIVATED PROTEIN KINASE 1, SULFATE ION | 著者 | Ward, R.A, Colclough, N, Challinor, M, Debreczeni, J.E, Eckersley, K, Fairley, G, Feron, L, Flemington, V, Graham, M.A, Greenwood, R, Hopcroft, P, Howard, T.D, James, M, Jones, C.D, Jones, C.R, Renshaw, J, Roberts, K, Snow, L, Tonge, M, Yeung, K. | 登録日 | 2015-04-10 | 公開日 | 2015-05-27 | 最終更新日 | 2015-08-26 | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | 主引用文献 | Structure-Guided Design of Highly Selective and Potent Covalent Inhibitors of Erk1/2. J.Med.Chem., 58, 2015
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4ZZO
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![BU of 4zzo by Molmil](/molmil-images/mine/4zzo) | Human ERK2 in complex with an irreversible inhibitor | 分子名称: | MITOGEN-ACTIVATED PROTEIN KINASE 1, N-[2-[[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]amino]phenyl]propanamide, SULFATE ION | 著者 | Ward, R.A, Colclough, N, Challinor, M, Debreczeni, J.E, Eckersley, K, Fairley, G, Feron, L, Flemington, V, Graham, M.A, Greenwood, R, Hopcroft, P, Howard, T.D, James, M, Jones, C.D, Jones, C.R, Renshaw, J, Roberts, K, Snow, L, Tonge, M, Yeung, K. | 登録日 | 2015-04-10 | 公開日 | 2015-05-27 | 最終更新日 | 2015-08-26 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Structure-Guided Design of Highly Selective and Potent Covalent Inhibitors of Erk1/2. J.Med.Chem., 58, 2015
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4ZZM
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![BU of 4zzm by Molmil](/molmil-images/mine/4zzm) | Human ERK2 in complex with an irreversible inhibitor | 分子名称: | 7-ethylsulfonyl-N-(oxan-4-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-amine, MITOGEN-ACTIVATED PROTEIN KINASE 1, SULFATE ION | 著者 | Ward, R.A, Colclough, N, Challinor, M, Debreczeni, J.E, Eckersley, K, Fairley, G, Feron, L, Flemington, V, Graham, M.A, Greenwood, R, Hopcroft, P, Howard, T.D, James, M, Jones, C.D, Jones, C.R, Renshaw, J, Roberts, K, Snow, L, Tonge, M, Yeung, K. | 登録日 | 2015-04-10 | 公開日 | 2015-05-27 | 最終更新日 | 2015-08-26 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structure-Guided Design of Highly Selective and Potent Covalent Inhibitors of Erk1/2. J.Med.Chem., 58, 2015
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