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5J75
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Fluorogen Activating Protein AM2.2 in complex with ML342
分子名称: N,4-dimethyl-N-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}benzene-1-sulfonamide, PHOSPHATE ION, scFv AM2.2
著者Stanfield, R.L, Wilson, I.A, Wu, Y.
登録日2016-04-05
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair.
J Biomol Screen, 21, 2016
1GGI
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BU of 1ggi by Molmil
CRYSTAL STRUCTURE OF AN HIV-1 NEUTRALIZING ANTIBODY 50.1 IN COMPLEX WITH ITS V3 LOOP PEPTIDE ANTIGEN
分子名称: HIV-1 V3 LOOP PEPTIDE ANTIGEN, IGG2A 50.1 FAB (HEAVY CHAIN), IGG2A 50.1 FAB (LIGHT CHAIN)
著者Stanfield, R.L, Rini, J.M, Wilson, I.A.
登録日1993-04-02
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of a human immunodeficiency virus type 1 neutralizing antibody, 50.1, in complex with its V3 loop peptide antigen.
Proc.Natl.Acad.Sci.USA, 90, 1993
4NJ9
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BU of 4nj9 by Molmil
Crystal structure of Fab 8B10 in complex with MPTS
分子名称: 8-methoxypyrene-1,3,6-trisulfonic acid, 8B10 heavy chain, 8B10 light chain, ...
著者Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A.
登録日2013-11-08
公開日2014-11-12
最終更新日2017-06-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation.
Biochemistry, 54, 2015
4NJA
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BU of 4nja by Molmil
Crystal structure of Fab 6C8 in complex with MPTS
分子名称: 6C8 heavy chain, 6C8 light chain, 8-methoxypyrene-1,3,6-trisulfonic acid, ...
著者Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A.
登録日2013-11-08
公開日2014-11-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation.
Biochemistry, 54, 2015
8GJV
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BU of 8gjv by Molmil
Chemical synthesis of maxamycins: Intermediate compound 10
分子名称: Intermediate compound 10 for maxamycins synthesis, METHANOL
著者Stanfield, R.L, Moore, M.J, Boger, D.L.
登録日2023-03-16
公開日2023-06-21
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献Divergent Total Synthesis and Characterization of Maxamycins.
J.Am.Chem.Soc., 145, 2023
2OJZ
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BU of 2ojz by Molmil
Anti-DNA antibody ED10
分子名称: Fab ED10 heavy chain, Fab ED10 light chain
著者Stanfield, R.L, Sanguineti, S, Wilson, I.A, de Prat-Gay, G.
登録日2007-01-15
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Specific recognition of a DNA immunogen by its elicited antibody
J.Mol.Biol., 370, 2007
2OK0
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Fab ED10-DNA complex
分子名称: 5'-D(*TP*C)-3', Fab ED10 heavy chain, Fab ED10 light chain
著者Stanfield, R.L, Sanguineti, S, Wilson, I.A, de Prat-Gay, G.
登録日2007-01-15
公開日2007-06-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Specific recognition of a DNA immunogen by its elicited antibody
J.Mol.Biol., 370, 2007
8ECZ
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BU of 8ecz by Molmil
Bovine Fab 4C1
分子名称: 4C1 Fab heavy chain, 4C1 Fab light chain, PHOSPHATE ION
著者Stanfield, R.L, Wilson, I.A.
登録日2022-09-02
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ECQ
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BU of 8ecq by Molmil
Bovine Fab 2G3
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2G3 Fab Heavy chain, 2G3 Fab Light chain, ...
著者Stanfield, R.L, Wilson, I.A.
登録日2022-09-02
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ED1
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BU of 8ed1 by Molmil
Bovine Fab 5C1
分子名称: 5C1 Fab heavy chain, 5C1 Fab light chain, GLYCEROL, ...
著者Stanfield, R.L, Wilson, I.A.
登録日2022-09-02
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EDF
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Bovine Fab SKD in complex with Sars COV-2 receptor binding domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SKD Fab Light chain, SKD Fab heavy chain, ...
著者Stanfield, R.L, Wilson, I.A.
登録日2022-09-04
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ECV
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BU of 8ecv by Molmil
Bovine Fab 2F12
分子名称: 2F12 Fab Heavy chain, 2F12 Fab Light chain
著者Stanfield, R.L, Wilson, I.A.
登録日2022-09-02
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
6CXL
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anti-HIV-1 Fab 2G12 in complex with glycopeptide 10F5
分子名称: alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose, anti-HIV-1 Fab 2G12 heavy chain, anti-HIV-1 Fab 2G12 light chain
著者Stanfield, R.L, Wilson, I.A.
登録日2018-04-03
公開日2019-02-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.586 Å)
主引用文献Oligomannose Glycopeptide Conjugates Elicit Antibodies Targeting the Glycan Core Rather than Its Extremities.
ACS Cent Sci, 5, 2019
6CXG
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BU of 6cxg by Molmil
anti-HIV-1 Fab 2G12 in complex with glycopeptide 10V1S
分子名称: 10V1S glycopeptide, GLYCEROL, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose, ...
著者Stanfield, R.L, Wilson, I.A.
登録日2018-04-03
公開日2019-02-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.298 Å)
主引用文献Oligomannose Glycopeptide Conjugates Elicit Antibodies Targeting the Glycan Core Rather than Its Extremities.
ACS Cent Sci, 5, 2019
4K3H
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BU of 4k3h by Molmil
Immunoglobulin lambda variable domain L5(L89S) fluorogen activationg protein in complex with malachite green
分子名称: 4-{bis[4-(dimethylamino)phenyl]methyl}phenol, GLYCEROL, Immunoglobulin lambda variable domain L5(L89S), ...
著者Stanfield, R.L, Szent-Gyorgyi, C, Wilson, I.A.
登録日2013-04-10
公開日2013-10-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Malachite Green Mediates Homodimerization of Antibody VL Domains to Form a Fluorescent Ternary Complex with Singular Symmetric Interfaces.
J.Mol.Biol., 425, 2013
4K3G
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Immunoglobulin lambda variable domain L5(L89S) fluorogen activating protein
分子名称: alpha-D-mannopyranose, immunoglobulin lambda variable domain L5(L89S)
著者Stanfield, R.L, Szent-Gyorgyi, C, Wilson, I.A.
登録日2013-04-10
公開日2013-10-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Malachite Green Mediates Homodimerization of Antibody VL Domains to Form a Fluorescent Ternary Complex with Singular Symmetric Interfaces.
J.Mol.Biol., 425, 2013
5T3S
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BU of 5t3s by Molmil
HIV gp140 trimer MD39-10MUTA in complex with Fabs PGT124 and 35022
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Stanfield, R.L, Wilson, I.A.
登録日2016-08-26
公開日2016-09-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.
Immunity, 45, 2016
5U64
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BU of 5u64 by Molmil
Camel nanobody VHH-28
分子名称: VHH-28
著者Stanfield, R.L, Wilson, I.A.
登録日2016-12-07
公開日2017-09-20
実験手法X-RAY DIFFRACTION (1.153 Å)
主引用文献Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers.
Sci Rep, 7, 2017
5U65
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Camel Nanobody VHH-5
分子名称: SULFATE ION, VHH-5
著者Stanfield, R.L, Wilson, I.A.
登録日2016-12-07
公開日2017-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers.
Sci Rep, 7, 2017
1W72
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BU of 1w72 by Molmil
Crystal structure of HLA-A1:MAGE-A1 in complex with Fab-Hyb3
分子名称: BETA-2-MICROGLOBULIN, GLYCEROL, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
著者Hulsmeyer, M, Chames, P, Hillig, R.C, Stanfield, R.L, Held, G, Coulie, P.G, Alings, C, Wille, G, Saenger, W, Uchanska-Ziegler, B, Hoogenboom, H.R, Ziegler, A.
登録日2004-08-27
公開日2004-11-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A Major Histocompatibility Complex.Peptide- Restricted Antibody and T Cell Receptor Molecules Recognize Their Target by Distinct Binding Modes: Crystal Structure of Human Leukocyte Antigen (Hla)-A1.Mage-A1 in Complex with Fab-Hyb3
J.Biol.Chem., 280, 2005
8W1N
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Structure of transthyretin pathogenic mutation A120S
分子名称: Transthyretin
著者Ferguson, J.A, Stanfield, R.L, Wright, P.E.
登録日2024-02-16
公開日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The mispacked F87 sidechain drives aggregation-promoting conformational fluctuations in transthyretin
To Be Published
8W2W
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Structure of transthyretin synthetic mutation A120L
分子名称: Transthyretin
著者Yang, K, Sun, X, Ferguson, J.A, Stanfield, R.L, Wright, P.E.
登録日2024-02-21
公開日2024-02-28
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献The mispacked F87 sidechain drives aggregation-promoting conformational fluctuations in transthyretin
To Be Published
3C2A
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BU of 3c2a by Molmil
Antibody Fab fragment 447-52D in complex with UG1033 peptide
分子名称: Envelope glycoprotein, Fab 447-52D heavy chain, Fab 447-52D light chain
著者Dhillon, A.K, Stanfield, R.L, Wilson, I.A.
登録日2008-01-24
公開日2008-07-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure determination of an anti-HIV-1 Fab 447-52D-peptide complex from an epitaxially twinned data set
Acta Crystallogr.,Sect.D, 64, 2008
2QSC
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BU of 2qsc by Molmil
Crystal structure analysis of anti-HIV-1 V3-Fab F425-B4e8 in complex with a V3-peptide
分子名称: CHLORIDE ION, Envelope glycoprotein gp120, Fab F425-B4e8, ...
著者Bell, C.H, Schiefner, A, Stanfield, R.L, Wilson, I.A.
登録日2007-07-30
公開日2008-01-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization.
J.Mol.Biol., 375, 2008
4F6N
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Crystal structure of Kaiso zinc finger DNA binding protein in complex with methylated CpG site DNA
分子名称: DNA (5'-D(*CP*GP*TP*AP*TP*AP*GP*AP*(5CM)P*GP*(5CM)P*GP*GP*TP*GP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*CP*AP*CP*(5CM)P*GP*(5CM)P*GP*TP*CP*TP*AP*TP*AP*CP*G)-3'), GLYCEROL, ...
著者Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E.
登録日2012-05-15
公開日2012-09-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
Proc.Natl.Acad.Sci.USA, 109, 2012

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