4FMK
 
 | | Crystal structure of mouse nectin-2 extracellular fragment D1-D2 | | 分子名称: | CADMIUM ION, Poliovirus receptor-related protein 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Harrison, O.J, Brasch, J, Shapiro, L. | | 登録日 | 2012-06-17 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Nectin ectodomain structures reveal a canonical adhesive interface.
Nat.Struct.Mol.Biol., 19, 2012
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4FMT
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4FQP
 | | Crystal structure of human Nectin-like 5 full ectodomain (D1-D3) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Poliovirus receptor, ... | | 著者 | Harrison, O.J, Jin, X, Brasch, J, Shapiro, L. | | 登録日 | 2012-06-25 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Nectin ectodomain structures reveal a canonical adhesive interface.
Nat.Struct.Mol.Biol., 19, 2012
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4FOM
 | | Crystal structure of human nectin-3 full ectodomain (D1-D3) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Poliovirus receptor-related protein 3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Harrison, O.J, Jin, X, Brasch, J, Shapiro, L. | | 登録日 | 2012-06-20 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.93 Å) | | 主引用文献 | Nectin ectodomain structures reveal a canonical adhesive interface.
Nat.Struct.Mol.Biol., 19, 2012
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3BL8
 | | Crystal structure of the extracellular domain of neuroligin 2A from mouse | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuroligin-2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Jin, X, Koehnke, J, Shapiro, L. | | 登録日 | 2007-12-10 | | 公開日 | 2008-02-19 | | 最終更新日 | 2021-03-31 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Crystal structure of the extracellular cholinesterase-like domain from neuroligin-2.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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5IRY
 | | Crystal structure of human Desmocollin-1 ectodomain | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Brasch, J, Harrison, O.J, Shapiro, L. | | 登録日 | 2016-03-15 | | 公開日 | 2016-06-22 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.095 Å) | | 主引用文献 | Structural basis of adhesive binding by desmocollins and desmogleins.
Proc.Natl.Acad.Sci.USA, 113, 2016
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7TTX
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7TTM
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7TTY
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7THK
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6XSK
 | | Cryo-EM Structure of Vaccine-Elicited Rhesus Antibody 789-203-3C12 in Complex with Stabilized SI06 (A/Solomon Islands/3/06) Influenza Hemagglutinin Trimer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 789-203-3C12 Fab Heavy Chain, ... | | 著者 | Cerutti, G, Gorman, J, Kwong, P.D, Shapiro, L. | | 登録日 | 2020-07-15 | | 公開日 | 2021-07-21 | | 最終更新日 | 2023-02-01 | | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | | 主引用文献 | Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses.
Immunity, 55, 2022
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7TXD
 | | Cryo-EM structure of BG505 SOSIP HIV-1 Env trimer in complex with CD4 receptor (D1D2) and broadly neutralizing darpin bnD.9 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Broadly neutralizing darpin bnd.9, ... | | 著者 | Cerutti, G, Gorman, J, Kwong, P.D, Shapiro, L. | | 登録日 | 2022-02-08 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | | 主引用文献 | Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization.
Nat.Struct.Mol.Biol., 30, 2023
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2V0C
 | | LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A SULPHAMOYL ANALOGUE OF LEUCYL-ADENYLATE In the synthetic site and an adduct of AMP with 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (AN2690) in the editing site | | 分子名称: | AMINOACYL-TRNA SYNTHETASE, LEUCINE, SULFATE ION, ... | | 著者 | Rock, F, Mao, W, Yaremchuk, A, Tukalo, M, Crepin, T, Zhou, H, Zhang, Y, Hernandez, V, Akama, T, Baker, S, Plattner, J, Shapiro, L, Martinis, S.A, Benkovic, S.J, Cusack, S, Alley, M.R.K. | | 登録日 | 2007-05-14 | | 公開日 | 2007-07-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site.
Science, 316, 2007
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2V0G
 | | LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A tRNA(leu) transcript with 5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1- BENZOXABOROLE (AN2690) forming an adduct to the ribose of adenosine- 76 in the enzyme editing site. | | 分子名称: | AMINOACYL-TRNA SYNTHETASE, LEUCINE, MERCURY (II) ION, ... | | 著者 | Rock, F, Mao, W, Yaremchuk, A, Tukalo, M, Crepin, T, Zhou, H, Zhang, Y, Hernandez, V, Akama, T, Baker, S, Plattner, J, Shapiro, L, Martinis, S.A, Benkovic, S.J, Cusack, S, Alley, M.R.K. | | 登録日 | 2007-05-14 | | 公開日 | 2007-07-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site.
Science, 316, 2007
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6WU5
 | | Human Calcium and Integrin Binding Protein 3 | | 分子名称: | CALCIUM ION, CHLORIDE ION, Calcium and integrin-binding family member 3, ... | | 著者 | Dionne, G, Shapiro, L. | | 登録日 | 2020-05-04 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells.
Neuron, 109, 2021
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7UKL
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8G4M
 | | Vaccine-elicited human antibody 2C06 in complex with HIV-1 envelope trimer BG505 DS-SOSIP | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | 著者 | Wang, S, Morano, N.C, Shapiro, L, Kwong, P.D. | | 登録日 | 2023-02-10 | | 公開日 | 2023-07-12 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide.
Cell Rep, 42, 2023
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7RW2
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8TNL
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8TOA
 | | CryoEM structure of H7 hemagglutinin from A/Shanghai2/2013 H7N9 in complex with a human neutralizing antibody H7.HK2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H7.HK2 Neutralizing Antibody Heavy Chain, H7.HK2 Neutralizing Antibody Light Chain, ... | | 著者 | Morano, N.C, Becker, J.E, Wu, X, Shapiro, L. | | 登録日 | 2023-08-03 | | 公開日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.69 Å) | | 主引用文献 | CryoEM structure of H7 hemagglutinin from A/Shanghai2/2013 H7N9 in complex with a human neutralizing antibody H7.HK1
To Be Published
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5ZJT
 | | Structure of AbdB/Exd complex bound to a 'Black14' DNA sequence | | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*GP*AP*TP*AP*AP*AP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*TP*TP*TP*AP*TP*CP*AP*TP*GP*C)-3'), Homeobox protein abdominal-B, ... | | 著者 | Zeiske, T, Baburajendran, N, Kaczynska, A, Mann, R, Honig, B, Shapiro, L, Palmer, A.G. | | 登録日 | 2018-03-22 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites.
Cell Rep, 24, 2018
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5ZJS
 | | Structure of AbdB/Exd complex bound to a 'Blue14' DNA sequence | | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*GP*AP*TP*TP*AP*AP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*TP*TP*AP*AP*TP*CP*AP*TP*GP*C)-3'), Homeobox protein abdominal-B, ... | | 著者 | Baburajendran, N, Zeiske, T, Kaczynska, A, Mann, R, Honig, B, Shapiro, L, Palmer, A.G. | | 登録日 | 2018-03-22 | | 公開日 | 2018-08-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.896 Å) | | 主引用文献 | Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites.
Cell Rep, 24, 2018
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5ZJR
 | | Structure of AbdB/Exd complex bound to a 'Magenta14' DNA sequence | | 分子名称: | DNA (5'-D(*GP*TP*CP*GP*TP*AP*AP*AP*TP*CP*AP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*TP*GP*AP*TP*TP*TP*AP*CP*GP*AP*C)-3'), Homeobox protein abdominal-B, ... | | 著者 | Zeiske, T, Baburajendran, N, Kaczynska, A, Mann, R, Honig, B, Shapiro, L, Palmer, A.G. | | 登録日 | 2018-03-22 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites.
Cell Rep, 24, 2018
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5ZJQ
 | | Structure of AbdB/Exd complex bound to a 'Red14' DNA sequence | | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*GP*AP*TP*TP*TP*AP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*TP*AP*AP*AP*TP*CP*AP*TP*GP*C)-3'), Homeobox protein abdominal-B, ... | | 著者 | Baburajendran, N, Zeiske, T, Kaczynska, A, Mann, R, Honig, B, Shapiro, L, Palmer, A.G. | | 登録日 | 2018-03-22 | | 公開日 | 2018-08-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.443 Å) | | 主引用文献 | Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites.
Cell Rep, 24, 2018
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7LSS
 | | Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-7 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 2-7 variable heavy chain, ... | | 著者 | Rapp, M, Shapiro, L. | | 登録日 | 2021-02-18 | | 公開日 | 2021-03-17 | | 最終更新日 | 2021-09-29 | | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | | 主引用文献 | Structural basis for accommodation of emerging B.1.351 and B.1.1.7 variants by two potent SARS-CoV-2 neutralizing antibodies.
Structure, 29, 2021
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