8CXC
| Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics | 分子名称: | 3F2 Antibody heavy chain, 3F2 Antibody light chain, Mesothelin, ... | 著者 | Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E. | 登録日 | 2022-05-20 | 公開日 | 2023-06-07 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (4.31 Å) | 主引用文献 | Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics Front. Drug Discov., 3, 2023
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8CZ8
| Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics | 分子名称: | Mesothelin, cleaved form, SULFATE ION, ... | 著者 | Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E. | 登録日 | 2022-05-24 | 公開日 | 2023-06-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics Front. Drug Discov., 3, 2023
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8CYH
| Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, A12 antibody heavy chain, A12 antibody light chain, ... | 著者 | Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E. | 登録日 | 2022-05-23 | 公開日 | 2023-06-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | 主引用文献 | Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics Front. Drug Discov., 3, 2023
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4LCI
| Anti canine CD28 antibody, 1C6 | 分子名称: | FORMIC ACID, GLYCEROL, SODIUM ION, ... | 著者 | Gewe, M.M, Rupert, P.B, Strong, R.K. | 登録日 | 2013-06-21 | 公開日 | 2014-06-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Anti canine CD28 antibody, 1C6 To be Published
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4LLV
| The structure of the unbound form of anti-HIV antibody 4E10 Fv | 分子名称: | 4E10 Fv heavy chain, 4E10 Fv light chain, GLYCEROL, ... | 著者 | Finton, K.A.K, Rupert, P.B, Strong, R.K. | 登録日 | 2013-07-09 | 公開日 | 2013-10-16 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Autoreactivity and Exceptional CDR Plasticity (but Not Unusual Polyspecificity) Hinder Elicitation of the Anti-HIV Antibody 4E10. Plos Pathog., 9, 2013
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7SRK
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7SR4
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7SR5
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7SR0
| Single chain trimer HLA-A*02:01 (H98L, Y108C) with HPV.16 E7 peptide YMLDLQPET | 分子名称: | PHOSPHATE ION, Protein E7 peptide,Beta-2-microglobulin,MHC class I antigen chimera, VHH | 著者 | Finton, K.A.K, Rupert, P.B. | 登録日 | 2021-11-07 | 公開日 | 2022-11-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Effects of HLA single chain trimer design on peptide presentation and stability. Front Immunol, 14, 2023
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7STG
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7ST3
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7SR3
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7SQP
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7SSH
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7U63
| Crystal Structure Anti-Oxycodone Antibody HY2-A12 Fab Complexed with Oxycodone | 分子名称: | 14-hydroxy-3-methoxy-17-methyl-5beta-4,5-epoxymorphinan-6-one, HY2-A12 Fab Heavy Chain, HY2-A12 Fab Light Chain | 著者 | Rodarte, J.V, Pancera, M.P, Weidle, C, Rupert, P.B, Strong, R.K. | 登録日 | 2022-03-03 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding. Structure, 31, 2023
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5JG9
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4JLR
| Crystal structure of a designed Respiratory Syncytial Virus Immunogen in complex with Motavizumab | 分子名称: | Motavizumab Fab heavy chain, Motavizumab Fab light chain, PENTAETHYLENE GLYCOL, ... | 著者 | Rupert, P.B, Correia, B, Schief, W, Strong, R.K. | 登録日 | 2013-03-12 | 公開日 | 2014-02-05 | 最終更新日 | 2014-12-17 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Proof of principle for epitope-focused vaccine design. Nature, 507, 2014
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7SNC
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7SND
| Pacifastin related protease inhibitors | 分子名称: | GLYCEROL, PHOSPHATE ION, Pacifastin-related peptide | 著者 | Gewe, M.M, Strong, R.K. | 登録日 | 2021-10-27 | 公開日 | 2022-08-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager. Sci Transl Med, 14, 2022
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3TNY
| Structure of YfiY from Bacillus cereus bound to the siderophore iron (III) schizokinen | 分子名称: | YfiY (ABC transport system substrate-binding protein), [2-(hydroxy-kappaO)-4-[(3-{(hydroxy-kappaO)[1-(hydroxy-kappaO)ethenyl]amino}propyl)amino]-2-{2-[(3-{(hydroxy-kappaO)[1- (hydroxy-kappaO)ethenyl]amino}propyl)amino]-2-oxoethyl}-4-oxobutanoato(6-)-kappaO]iron | 著者 | Clifton, M.C. | 登録日 | 2011-09-02 | 公開日 | 2012-09-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Parsing the functional specificity of Siderocalin / Lipocalin 2 / NGAL for siderophores and related small-molecule ligands To be Published
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3TZS
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3CMP
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3T1D
| The mutant structure of human Siderocalin W79A, R81A, Y106F bound to Enterobactin | 分子名称: | 2,3-DIHYDROXY-BENZOIC ACID, 2-(2,3-DIHYDROXY-BENZOYLAMINO)-3-HYDROXY-PROPIONIC ACID, CHLORIDE ION, ... | 著者 | Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2011-07-21 | 公開日 | 2011-08-17 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Parsing the functional specificity of Siderocalin/Lipocalin 2/NGAL for siderophores and related small-molecule ligands. J Struct Biol X, 2, 2019
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3TF6
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6ATS
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